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M. marinum M MMAR_2840 (atsD_2)

annotation: arylsulfatase AtsD_2
coordinates: 3445237 - 3447564
length: 775

MVDLPRNEQPFGGVINPVVADSTPVTPSIDYPPDGAPNVVVVLLDDVGFGAPSTFGGPVPTPTLDRIAQA
GLRYNQFHTTALCSPTRAALLTGRNHHSAHMGTICEIAYGFPGYDSVLPQSTATIAQILRMNGYNTALFG
KAHFTPTWEIGPAGPFDRWPTGLGFERFYGFLGGDTSQYEPALFDQTTPVEPYVGRDDYHLTEDLADKAI
EWIQRQQTSAPDKPFLLYLAPGATHSPHHVWPEWSDRFAGQFDEGWDALREQTYARQLERGIIPPGTQLT
PRPEQIPAWADYDDRYKPVARRLMEVYAGFLAHTDAQIGRVVDAIDDLGQWENTLFIYICGDNGASAEGT
VHGAWSSPSFQNGLPEDPEWLLAHLADFGTVRCENHYNVGWAWALDSPFQWMKQVASHFGGTRNGMAVSW
PRGITCAGEQRSQFHHVIDVVPTILEAAGIEMPERVNGIEQKPIEGVSMRYSFDEADAHSRRRTQYFEIF
GNRAIYHEGWIASCFHGRLPWVRTQRTNPFGDSERWELYHLADDFSQGVDLAEQYPDKLAELQAVFDTEA
RKYDVYPLSDATLARALPANRPNLLAGRTSATYYPSHVRIPETSTLPYTSTSFELRAQLQIPRGGAQGVV
ICIGGSMGGWSLYLQDGIPTFAYNYLGHELTTVAATDPLPEGQITLALSFDYDGGGLGKGALVTLLVDGT
TVANGRVEQTVPFRFSMSGETLDVGLDTGSPVAPYEHSFPFTGRIHRIDASVSPRPADLAAALSDIEMRA
ALGSQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2840atsD_2-100% (775)arylsulfatase AtsD_2
M. marinum MMMAR_1375atsD_10.055.61% (748) arylsulfatase AtsD_1
M. marinum MMMAR_4950atsD0.053.67% (708) arylsulfatase AtsD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0682atsD0.051.48% (775) arylsulfatase AtsD
M. gilvum PYR-GCKMflv_5039-1e-15839.51% (772) sulfatase
M. tuberculosis H37RvRv0663atsD0.051.35% (775) arylsulfatase AtsD
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4307-1e-15640.19% (749) arylsulfatase AtsA
M. avium 104MAV_4461-1e-15338.56% (791) arylsulfatase
M. smegmatis MC2 155MSMEG_1451-1e-15639.74% (770) arylsulfatase
M. thermoresistible (build 8)TH_0315-1e-16240.86% (788) arylsulfatase
M. ulcerans Agy99MUL_2500atsD_10.055.49% (710) arylsulfatase AtsD_1
M. vanbaalenii PYR-1Mvan_4467-0.053.32% (737) sulfatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5039|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_1451|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4461|M.avium_104                --------------------------------------------------
TH_0315|M.thermoresistible__bu      --------------------------------------------------
MAB_4307|M.abscessus_ATCC_1997      MHIPGDDAPEPEQNAERGRLTRRSMLGGIAAAGMGVAAASALVAGCDDDS
MMAR_2840|M.marinum_M               --------------------------------------------------
MUL_2500|M.ulcerans_Agy99           --------------------------------------------------
Mb0682|M.bovis_AF2122/97            --------------------------------------------------
Rv0663|M.tuberculosis_H37Rv         --------------------------------------------------
Mvan_4467|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_5039|M.gilvum_PYR-GCK          ------------MTTEFNGKIALDIRDSEPDWGPFAAPTAQPEAPNVLYL
MSMEG_1451|M.smegmatis_MC2_155      ------------MAAEFNGKIELDIRDSEPDWGPFAAPTAAEGAPNVLYV
MAV_4461|M.avium_104                ------MVAGSGQSAEFSGRVELDIRDSEPDWGPYAAPTAPPNAPNILYL
TH_0315|M.thermoresistible__bu      -------------MADFGGKIELDIRDSEPDWGPFAAPTAPEGAPNILYV
MAB_4307|M.abscessus_ATCC_1997      SSRTDRSSAAEEANAGFNGKIELDVRDSKPDWTPYELKHAPDGAPNVLVV
MMAR_2840|M.marinum_M               ------MVDLPRNEQPFGGVINPVVADSTPVTPSID--YPPDGAPNVVVV
MUL_2500|M.ulcerans_Agy99           -------------------------------------------------M
Mb0682|M.bovis_AF2122/97            --MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLI
Rv0663|M.tuberculosis_H37Rv         --MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLI
Mvan_4467|M.vanbaalenii_PYR-1       ----MRRDILPIPDPQHVGLTTYDAKDPDTTYPPITPLRPPQGAPNVLIV
                                                                                     :

Mflv_5039|M.gilvum_PYR-GCK          VWDDIGIATWDCFGGLVDMPAMSRIAERGVRLSQFHTTALCSPTRASLLT
MSMEG_1451|M.smegmatis_MC2_155      VWDDIGIATWDCFGGLVEMPAMSRIAEHGVRLSQFHTTALCSPTRAALLT
MAV_4461|M.avium_104                VWDDTGIATWDCFGGLVEMPAMSRIAERGVRLSQFHTTALCSPTRAALLT
TH_0315|M.thermoresistible__bu      VWDDVGIGTWDCFGGLVEMPTMSRIAEQGVRLSQFHTTALCSPTRAALLT
MAB_4307|M.abscessus_ATCC_1997      LFDDTGMATWSPYGGRVNMPTLQRLADNGLTYSQWHTTALCSPTRSCLLT
MMAR_2840|M.marinum_M               LLDDVGFGAPSTFGGPVPTPTLDRIAQAGLRYNQFHTTALCSPTRAALLT
MUL_2500|M.ulcerans_Agy99           LLDDVGFGATATFGGPVETPAGDALAQEGLRYNRFHTTALCSPTRAALLT
Mb0682|M.bovis_AF2122/97            LLDDVGFGASSAFGGPCRTSTAELLAGNGLRYNRFHTTALCSPTRQALLT
Rv0663|M.tuberculosis_H37Rv         LLDDVGFGASSAFGGPCRTSTAELLAGNGLRYNRFHTTALCSPTRQALLT
Mvan_4467|M.vanbaalenii_PYR-1       LLDDVGFGASSAFGGPCATPTAERLAANGLKLNRFHTTALCSPTRQALLT
                                    : ** *:.:   :**    .: . :*  *:  .::********** .***

Mflv_5039|M.gilvum_PYR-GCK          GRNATTVGMATIEEFTDGFPNCNGRIPFDTALLSEVLSENGYNTYCIGKW
MSMEG_1451|M.smegmatis_MC2_155      GRNPTTVGMATIEEFTDGFPNCSGRIPFETALLPEVLAENGYNTYCIGKW
MAV_4461|M.avium_104                GRNATTVGMATIEEFTEGFPNANGRIPFDTALLSEALAEHGYNTYCVGKW
TH_0315|M.thermoresistible__bu      GRNPTTVGMATIEEFTDGFPNCSGRIPVDTGLISEVLAEHGWNTYCVGKW
MAB_4307|M.abscessus_ATCC_1997      GRNHHVNRFASITEGSDGYPGAAGRLPAQCATIGQVLQDNGYSTFWVGKN
MMAR_2840|M.marinum_M               GRNHHSAHMGTICEIAYGFPGYDSVLPQSTATIAQILRMNGYNTALFGKA
MUL_2500|M.ulcerans_Agy99           GRNHHVVNTGTITEFATGYDGYNCIIPKSAATVAETLRQNGYSTAAFGKW
Mb0682|M.bovis_AF2122/97            GRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKC
Rv0663|M.tuberculosis_H37Rv         GRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKC
Mvan_4467|M.vanbaalenii_PYR-1       GRNHHSVGMGGVTEIATSAPGYSSIRPKDKAPVAETLRLNGYSTSQFGKC
                                    ***      . : * : .  .     *   . : . *  :*:.*  .** 

Mflv_5039|M.gilvum_PYR-GCK          HLTPLEESNLAATKRHWPLS-RGFERFYGFMGGETDQWYPDLMYDNHPVA
MSMEG_1451|M.smegmatis_MC2_155      HLTPLEESNLASTKRHWPCS-RGFERFYGFMGGETDQWYPDLTYDNHPVD
MAV_4461|M.avium_104                HLTPLEESNMASTKRHWPTS-RGFERFYGFLGGETDQWYPDLVYDNHPVS
TH_0315|M.thermoresistible__bu      HLTPLEESNMAATKRHWPVS-RGFERFYGFLGGETDQWYPDLVHDNHPVA
MAB_4307|M.abscessus_ATCC_1997      HNVPQEDVSCGGSKSEWPLQ-KGFDRYYGFLGGETNNWYPDLVEDNRFIE
MMAR_2840|M.marinum_M               HFTPTWEIGPAGPFDRWPTG-LGFERFYGFLGGDTSQYEPALFDQTTPVE
MUL_2500|M.ulcerans_Agy99           HNTPVWEVSAAGPFDRWPTG-MGLEEFYGFMGGEAHQYNPGLYHGTTPIE
Mb0682|M.bovis_AF2122/97            HEVPVWQTSPVGPFDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVE
Rv0663|M.tuberculosis_H37Rv         HEVPVWQTSPVGPFDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVE
Mvan_4467|M.vanbaalenii_PYR-1       HEVPVWEVSPVGPFGQWPTG-SGFEHFYGFIGGEANQYYPGLYEGTKPVE
                                    * .*  : .  ..   **    *:: :***:**:: :: * *   .  : 

Mflv_5039|M.gilvum_PYR-GCK          PPATPEEGYHLSKDLADKTIEFIRDSKVIAPDKPWFSYVCPGAGHAPHHV
MSMEG_1451|M.smegmatis_MC2_155      PPATPEEGYHLSKDLADKTIEFIRDAKVVASDKPWFTYLCPGAGHAPHHV
MAV_4461|M.avium_104                PPATPEDGYHLSKDLADKTIEFIRDAKVIAPEKPWFSYVCPGAGHAPHHV
TH_0315|M.thermoresistible__bu      PPATPEDGYHLSKDLADKTIEFIRDAKVIAPDKPWFTYLCPGAGHAPHHA
MAB_4307|M.abscessus_ATCC_1997      QPTSPEQGYHLSKDLADQALRMLRDQRNTNPSKPWYMWFCPGANHAPHHS
MMAR_2840|M.marinum_M               PYVGRDD-YHLTEDLADKAIEWIQRQQTSAPDKPFLLYLAPGATHSPHHV
MUL_2500|M.ulcerans_Agy99           RPEDAED-YHLSTDLADRMIEWVHRQRAMAPDRPFFAYWAPGATHAPHHV
Mb0682|M.bovis_AF2122/97            VNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPGATHAPHHV
Rv0663|M.tuberculosis_H37Rv         VNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPGATHAPHHV
Mvan_4467|M.vanbaalenii_PYR-1       PEKTPEQGYTLTEDLADRAITWVRQQQALTPDKPFFMYFAPGATHAPHHV
                                         :: * :  *::*: :  :   :   ..:*:  : .*** *:*** 

Mflv_5039|M.gilvum_PYR-GCK          FKEWADRYAGRFDMGYEAYREIVLENQKRLGLVPPDTELSAVNPYLDVKG
MSMEG_1451|M.smegmatis_MC2_155      FKEWADRYKGRFDMGYERYREIVLENQKRMGLVPPDTELSPVNPYSEVTG
MAV_4461|M.avium_104                FKEWADRYAGRFDMGYERYREVVLERQKAMGIVPSDTELSPVNPYLDVTG
TH_0315|M.thermoresistible__bu      PRDWADRYAGRFDMGYERYREVVLENQKKLGIVPPDTELPPINPYQDVKG
MAB_4307|M.abscessus_ATCC_1997      PAEYADKYRGKFDDGYEAYREWVLARMIDKGIMPRETKLTPINPLPNDVA
MMAR_2840|M.marinum_M               WPEWSDRFAGQFDEGWDALREQTYARQLERGIIPPGTQLTPRP-------
MUL_2500|M.ulcerans_Agy99           APEWSDPFRGRFDQGWDVLREEIFARQKRLGVIPADAELTERH-------
Mb0682|M.bovis_AF2122/97            PREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARH-------
Rv0663|M.tuberculosis_H37Rv         PREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARH-------
Mvan_4467|M.vanbaalenii_PYR-1       PKQWSDKYRGKFDDGWDVLRESMLDNQKALGVVPEDAQLTARH-------
                                      :::* : *:** *::  **    .    *::*   :*.          

Mflv_5039|M.gilvum_PYR-GCK          PDGQDWPAQDTVRPWDSLSEDEKRLFARMAEVFAGFLSYTDAQIGRVLDY
MSMEG_1451|M.smegmatis_MC2_155      PDGQPWPAQDTVRPWDSLSDDEKALFCRMAEVFAGFLSYTDAQIGRVLDY
MAV_4461|M.avium_104                PSGEPWPLQDTVRPWDSLNDEEKKLFARMAEVFAGFLSYTDAQIGRILDY
TH_0315|M.thermoresistible__bu      PHGEPWPLQDTVRPWDSLSDAEKRLFCRMAEVFAGFLSYTDHQIGRVLDY
MAB_4307|M.abscessus_ATCC_1997      VEA------DSVRPWNTLNPDEKRLFSRMAEVFAGFSEYTDAQVGRVIDY
MMAR_2840|M.marinum_M               ---------EQIPAWADYDDRYKPVARRLMEVYAGFLAHTDAQIGRVVDA
MUL_2500|M.ulcerans_Agy99           ---------ESLPAWDSLPEQRQRIASRLMEVYAGFLAHTDHEVGRIMDA
Mb0682|M.bovis_AF2122/97            ---------AEIPAWDDMPEDLKPVLCRQMEVYAGFLEYTDHHVGRLVDG
Rv0663|M.tuberculosis_H37Rv         ---------AEIPAWDDMPEDLKPVLCRQMEVYAGFLEYTDHHVGRLVDG
Mvan_4467|M.vanbaalenii_PYR-1       ---------DEIPAWDDMPDVLKPVLARQMEIYAGFLEQTDHEIGRLVDA
                                               : .*       : :  *  *::***   ** .:**::* 

Mflv_5039|M.gilvum_PYR-GCK          LEESGQLDNTVIVVIS-DNGASGEGGPNGSVNEVKFFNGYI--DSAEESL
MSMEG_1451|M.smegmatis_MC2_155      LEESGQIDNTIIVVIS-DNGASGEGGPNGSVNETKFFNGYI--DTAEEGL
MAV_4461|M.avium_104                LEESGQLDDTIIVVIS-DNGASGEGGPNGSVNEGKFFNGYI--DTVEESM
TH_0315|M.thermoresistible__bu      LEESDQLDNTLIVVLS-DNGASGEGGPDGSVNEVKFFNGYV--DTVEESM
MAB_4307|M.abscessus_ATCC_1997      LEQTGQLDNTVVFYCA-DNGASGEGSPNGSVNENKFFNGYP--DDLAENM
MMAR_2840|M.marinum_M               IDDLGQWENTLFIYICGDNGASAEGTVHGAWSSPSFQNGLP--EDPEWLL
MUL_2500|M.ulcerans_Agy99           LKEIGVWDNTLFIYIIGDNGAAPGGGHGGVFNEMVTLNGLQ--EDVDVVL
Mb0682|M.bovis_AF2122/97            LQRLGVLDDTLVFYIIGDNGASAEGTINGTYNEMLNFNGLADIETPRFMT
Rv0663|M.tuberculosis_H37Rv         LQRLGVLDDTLVFYIIDDNGASAEGTINGTYNEMLNFNGLADIETPRFMT
Mvan_4467|M.vanbaalenii_PYR-1       IDDLGALDNTLIYYIIGDNGASAEGTPNGCFNEMCTLNGLAGIETPEFLL
                                    :.  .  ::*:.     ****:  *   *  ..    **    :      

Mflv_5039|M.gilvum_PYR-GCK          KVFDELGGPQTYNHYPIGWAMAFNTPYKLFKRYASHEGGIADTAIISWPK
MSMEG_1451|M.smegmatis_MC2_155      KFIDKLGGPQTYNHYPIGWAMAFNTPYKLFKRYASHEGGIADPAIISWPK
MAV_4461|M.avium_104                KLFDQLGGPQTYNHYPIGWAMAFNTPYKLYKRYASHEGGIADTAIISWPN
TH_0315|M.thermoresistible__bu      RFYDQLGGPQTYNHYPTGWAMAFNTPYKLFKRYASHEGGIADPAIISWPN
MAB_4307|M.abscessus_ATCC_1997      KYIDRLGTPDTYNHYPTGWAVAFSTPFQMFKRYSQFSGGTCDPLVIHWPK
MMAR_2840|M.marinum_M               AHLADFGTVRCENHYNVGWAWALDSPFQWMKQVASHFGGTRNGMAVSWPR
MUL_2500|M.ulcerans_Agy99           SKMDEIGGPRASNEYPVGFAWAMCTPFQFTKQFASHFGGTRNPMIVSWPA
Mb0682|M.bovis_AF2122/97            DRLDKFGGPESYNHYSVGWAHAMDTPYQWTKQVASHWGGTRNGTIVHWPN
Rv0663|M.tuberculosis_H37Rv         DRLDKFGGPESYNHYSVGWAHAMDTPYQWTKQVASHWGGTRNGTIVHWPN
Mvan_4467|M.vanbaalenii_PYR-1       SKIDDFGTPDAYNHYAVGWAHALCGPYQWTKQVASHWGGTRNGTIVHWPN
                                         :*     *.*  *:* *:  *::  *: :.. **  :   : ** 

Mflv_5039|M.gilvum_PYR-GCK          GIAAHGEIRDNYVNVADITPTVYDLLDITPPATVRGVAQKPLDGVSFKVA
MSMEG_1451|M.smegmatis_MC2_155      GIAARGEVRDNYVNVCDVTPTVYDMLGITPPATVRGVPQKPLDGVSFKAA
MAV_4461|M.avium_104                GIAAHGEIRDNYVNVCDITPTVYDLLGMSPPETVKGIAQKPLDGVSFKAA
TH_0315|M.thermoresistible__bu      GITARDAVCDRYINVVDVTPTVYELIGLTPPDTVRGVRQRPLEGVSFRAA
MAB_4307|M.abscessus_ATCC_1997      GIKAKGEVRHQYHHVTDIVPTILDVAGLTMPETYRGVDQFPVNGVSMRYT
MMAR_2840|M.marinum_M               GITCAGEQRSQFHHVIDVVPTILEAAGIEMPERVNGIEQKPIEGVSMRYS
MUL_2500|M.ulcerans_Agy99           RITDRGGLRSQFHHVVDIAPTILEAAGIPAPEIVNGVAQKPHDGISLMYT
Mb0682|M.bovis_AF2122/97            GIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMAYS
Rv0663|M.tuberculosis_H37Rv         GIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMAYS
Mvan_4467|M.vanbaalenii_PYR-1       GIAAKGETRNQFHHVIDVVPTILEAAKLPAPTVVNSIQQAPLEGVSMMST
                                     *   .    .: :* *:.**: :   :  *   ..: * * :*:*:  :

Mflv_5039|M.gilvum_PYR-GCK          LENPNAPTGKETQFYTMLGTRGIWHRGWFANTVHAASPAGWS-----HFD
MSMEG_1451|M.smegmatis_MC2_155      LADPDAPTGKETQFYAMLGTRGIWHKGWFANTVHAATPSGWG-----HFA
MAV_4461|M.avium_104                LDDPNADTGKTTQFYTMLGTRGIWHEGWFANTVHAATPAGWS-----HFD
TH_0315|M.thermoresistible__bu      LADPDADTGKRTQFYSMLGTRGIWSDGWFANTVHAASPAGWS-----NFD
MAB_4307|M.abscessus_ATCC_1997      FDDKDAATTKKRQYYAMLGTRGIWEDGWKASALHAP-ISGKG-----HFD
MMAR_2840|M.marinum_M               FDEADAHSRRRTQYFEIFGNRAIYHEGWIASCFHGRLPWVRTQRTNPFGD
MUL_2500|M.ulcerans_Agy99           FDDAEAADRRRTQYFEIGGLRGIYHEDWMACTYHGRILWRPGALP-AFSD
Mb0682|M.bovis_AF2122/97            FDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKH-KTPWILVGEQTVAFD
Rv0663|M.tuberculosis_H37Rv         FDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKH-KTPWILVGEQTVAFD
Mvan_4467|M.vanbaalenii_PYR-1       LRDRDADETHTVQYFEMFGNRGIYHKGWTAVTKH-RTPWIAD---QPPLD
                                    : : :*   :  *:: : * *.*:  .* *   *                

Mflv_5039|M.gilvum_PYR-GCK          DDRWELYHVDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLPLGDLD
MSMEG_1451|M.smegmatis_MC2_155      DDRWELFHIDADRSQCHDLAAEHPDRLEELKALWFSEADKYNGLPLGDLS
MAV_4461|M.avium_104                ADRWELFHIEADRSQCHDLAAENPDKLEELKALWFAEAARYNGLPLSDLN
TH_0315|M.thermoresistible__bu      ADRWELYHLESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLPLGDLN
MAB_4307|M.abscessus_ATCC_1997      QDKWELFHVDEDRSESTDLADQHPDKLKALIDAWFEEADNNFVLPLDDRL
MMAR_2840|M.marinum_M               SERWELYHLADDFSQGVDLAEQYPDKLAELQAVFDTEARKYDVYPLSD--
MUL_2500|M.ulcerans_Agy99           -DRWEFYDLFRDYSQAADLSAQFPDKLEQLKALFDAEGVKNNVFPLDDR-
Mb0682|M.bovis_AF2122/97            DDVWELYDTTKDWSQAKDLAKEMPEKLHELQRLWLIEATRYNVLPLDDDT
Rv0663|M.tuberculosis_H37Rv         DDVWELYDTTKDWSQAKDLAKEMPEKLHELQRLWLIEATRYNVLPLDDDT
Mvan_4467|M.vanbaalenii_PYR-1       EDVWELYAP-DDWTQAHDLAAEQPERLAALQRLWLIEAVKYNVVPLDDRS
                                     : **::    * ::  **: : *::*  *   :  *. .    **.*  

Mflv_5039|M.gilvum_PYR-GCK          ---IFETMSRWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLAEV
MSMEG_1451|M.smegmatis_MC2_155      ---ILETTTRWRPYLTGERTSYTYYPHTAEVGMGAVVELRGQSFKVLAEV
MAV_4461|M.avium_104                ---ILETMTRSRPYLVGERDSYVYYPDCADVGIGAAAEIRGRSFSVLAEA
TH_0315|M.thermoresistible__bu      ---LFETLGRWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLADV
MAB_4307|M.abscessus_ATCC_1997      ---PTELLTIERPQFEPRRNRYLYYPDASPVPEGVAVNIRGKSYKIVANT
MMAR_2840|M.marinum_M               -ATLARALPANRPNLLAGRTSATYYPSHVRIPETSTLPYTSTSFELRAQL
MUL_2500|M.ulcerans_Agy99           -GRLARALEP-RPTILGERTSISFRQGATRIPEDIIRSAFNRSYSITAVI
Mb0682|M.bovis_AF2122/97            ASRINPDLAG-RPVLIRG-NTQVLFSNMGRLSENCVLNLKNKSHTVTAEV
Rv0663|M.tuberculosis_H37Rv         ASRINPDLAG-RPVLIRG-NTQVLFSNMGRLSENCVLNLKNKSHTVTAEV
Mvan_4467|M.vanbaalenii_PYR-1       FERFNPDIAG-RPQLIKG-TTQTLFSGM-RLLENCVLNIKNRSHAVSALI
                                               ** :               :         . *. : *  

Mflv_5039|M.gilvum_PYR-GCK          EVDPGG-ANGVVVKHGGAHGGYVMYLQGGRLHFCYNFLGEYEQTLAAPDP
MSMEG_1451|M.smegmatis_MC2_155      TVDSAE-AQGVIFKHGGAHGGHVLFIADGHLHYVYNFLGEREQVLSAPDP
MAV_4461|M.avium_104                TVDTTG-AEGVLFKQGGAHGGHVLFIQDGRLHYVYNFLGERQQEVSSSVP
TH_0315|M.thermoresistible__bu      TVDAAG-AQGVIVKHGAGHGGYVLFLQDGRLHFVYNFMGEEEQRVSSADP
MAB_4307|M.abscessus_ATCC_1997      DIS-AQ-AQGVIFAHGSRFGGHVLFIKDGRLHYVYNFLGIKPEQEFISAP
MMAR_2840|M.marinum_M               QIPRGG-AQGVVICIGGSMGGWSLYLQDGIPTFAYNYLGHELTTVAATDP
MUL_2500|M.ulcerans_Agy99           DTPGGSTVEGVLLAAGGYFAGLSLYVQQGIPKFTYNYFGSTYTTVAATEA
Mb0682|M.bovis_AF2122/97            EVPETG-AEGVIVAQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADP
Rv0663|M.tuberculosis_H37Rv         EVPETG-AEGVIVAQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADP
Mvan_4467|M.vanbaalenii_PYR-1       SVPDSG-AQGVIVSQGGGVGGWCVYAHENTLKYCYNFFGIEYYFVTAELP
                                           .:**:.  *.  .*  ::   .   : **  *          .

Mflv_5039|M.gilvum_PYR-GCK          VPPGLHTLGFTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPGTF
MSMEG_1451|M.smegmatis_MC2_155      VPLGHHIFGVRYERTGTVPNSHTPVGVATLFVDGGAVADLADVQTHPAIF
MAV_4461|M.avium_104                VPLGRHLFGASYARTGTVPDSHTPLGDLTLFIDDEVVGTLAGVSTHPGTF
TH_0315|M.thermoresistible__bu      IPAGRHILGVSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPANF
MAB_4307|M.abscessus_ATCC_1997      LTPGNRTLGVEFVRRDKGQYGES-LGTTNLYVDGKLAATGP-MRTQVGTF
MMAR_2840|M.marinum_M               LPEGQITLALSFDYDG---GGLGKGALVTLLVDGTTVANGRVEQTVPFRF
MUL_2500|M.ulcerans_Agy99           LPAGKATVAMEFDYDG---GGLGKGGLVRLLLNGRDVGQSRIERTVPLGF
Mb0682|M.bovis_AF2122/97            LPAGAHQVRMEFAYAG---GGLGKGGEVTLYVDGQQVGEGHVEATLAIVF
Rv0663|M.tuberculosis_H37Rv         LPAGAHQVRMEFAYAG---GGLGKGGEVTLYVDGQQVGEGHVEATLAIVF
Mvan_4467|M.vanbaalenii_PYR-1       LPGGQHLVGFEFAYDG---GGLGKGGTVTLYCDGEPVGTGRVERTEPMAF
                                    :. *   .   :   .    .    .   *  :   ..      :    *

Mflv_5039|M.gilvum_PYR-GCK          GLAGASLSVGRNNGSPVSEAYHPPFAFAGGRIARVNIDTS-----GAPYV
MSMEG_1451|M.smegmatis_MC2_155      ALAGGGIAVGRNTGSGVSRSYRVPFPFTGGEIAQVTVDLS-----GEPYE
MAV_4461|M.avium_104                GLAGAGITVGRNGGSGVSSRFKAPFVFTGGTIARVTLDLS-----GRPYR
TH_0315|M.thermoresistible__bu      GLAGGGIAVGRNTGQPVSSAYRAPFAFTGGSIAKVIVDIS-----GTPYR
MAB_4307|M.abscessus_ATCC_1997      TLAGDGLCVGYDSGDNVSPQYTNPGRFTGGTIKVVAVDVS-----DESFI
MMAR_2840|M.marinum_M               SMSGETLDVGLDTGSPVAP-YEHSF-PFTGRIHRIDASVSPRPADLAAAL
MUL_2500|M.ulcerans_Agy99           SAD-EGVDIGMDCGTPAADTYEGTF-VFNATIEQVTIQLR----------
Mb0682|M.bovis_AF2122/97            SAD-DGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLV
Rv0663|M.tuberculosis_H37Rv         SAD-DGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLV
Mvan_4467|M.vanbaalenii_PYR-1       SAD-EACDVGSDTGSPTSPDYGPHGNGFNGRIDWVKIDIS--TDDHEHLI
                                            :* : *  .:  :        . *  :               

Mflv_5039|M.gilvum_PYR-GCK          DLERDFARAFARD
MSMEG_1451|M.smegmatis_MC2_155      DLVTRRATAFARD
MAV_4461|M.avium_104                DVETEIALAFSRD
TH_0315|M.thermoresistible__bu      DVEREAAMAFARD
MAB_4307|M.abscessus_ATCC_1997      DLEKEAQAAFARD
MMAR_2840|M.marinum_M               S-DIEMRAALGSQ
MUL_2500|M.ulcerans_Agy99           -------------
Mb0682|M.bovis_AF2122/97            DPEHAIRIALARQ
Rv0663|M.tuberculosis_H37Rv         DPEHAIRIALARQ
Mvan_4467|M.vanbaalenii_PYR-1       TPQDRFNISMARQ