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CRLFGLHAGRDCVTATFWLLNAPDSLAAQSKRNPDGTGLGVFDDRGRPELHKQPIAAWQDADFAAEAHEM TGTTFIAHVRYATAGSHSVVNTHPFLQDGRIFAHNGTLGDLELLDTRLREVGTAGLVQGQTDSERVFALI TAAIRTHDGDVSAGLLDAMGWLAANVPIYAVNVLLSTATGMWALRYPESHNLYILDRRNGAPAPRREFHL RTKRIRARSEHLRTRPSVVFASQPMDDDPRWRLLDPGELVHVDVDLRITRSLALPDPPRHRLRLADLGPE VQEALHPPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4405 | - | - | 100% (290) | hypothetical protein MMAR_4405 |
| M. marinum M | MMAR_5213 | - | 5e-08 | 26.77% (269) | hypothetical protein MMAR_5213 |
| M. marinum M | MMAR_1114 | glmS | 8e-07 | 26.45% (155) | glucosamine-fructose-6-phosphate aminotransferase, GlmS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1090 | - | 1e-124 | 74.91% (291) | hypothetical protein Mb1090 |
| M. gilvum PYR-GCK | Mflv_2003 | - | 2e-98 | 61.11% (288) | glutamine amidotransferase, class-II |
| M. tuberculosis H37Rv | Rv1061 | - | 1e-124 | 74.91% (291) | hypothetical protein Rv1061 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0713 | - | 5e-06 | 25.09% (267) | amidophosphoribosyltransferase |
| M. avium 104 | MAV_1188 | - | 1e-115 | 70.73% (287) | glutamine amidotransferase, class-II |
| M. smegmatis MC2 155 | MSMEG_6248 | - | 2e-09 | 27.82% (248) | hypothetical protein MSMEG_6248 |
| M. thermoresistible (build 8) | TH_0065 | - | 2e-10 | 28.96% (221) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0220 | - | 1e-168 | 98.63% (292) | hypothetical protein MUL_0220 |
| M. vanbaalenii PYR-1 | Mvan_2921 | - | 6e-09 | 30.00% (180) | glutamine amidotransferase, class-II |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4405|M.marinum_M -MCRLFGLHAGRDCVTATFWLLNAPDSLAAQSKR---------NPDGTGL
MUL_0220|M.ulcerans_Agy99 -MCRLFGLHAGRDCVTATFWLLNAPDSLAAQSKR---------NPDGTGL
Mb1090|M.bovis_AF2122/97 -MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRR---------NPDGTGL
Rv1061|M.tuberculosis_H37Rv -MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRR---------NPDGTGL
MAV_1188|M.avium_104 -MCRLFGLHAGTRACTATFWLLDAPDSLAEQSRR---------NPDGTGL
Mflv_2003|M.gilvum_PYR-GCK -MCRLFGLHAG-RPVAATFWLLDAPNSLAQQSRR---------NPDGTGL
MSMEG_6248|M.smegmatis_MC2_155 -MCRHVAWLGAPRSLAD--LVLDPPQGLLVQSYAPRRQKHGLMNADGWGA
TH_0065|M.thermoresistible__bu -MCRHLGWLGRPRSIAE--LMLEPPYGLLVQSYAPRRQKYGLLNADGWGV
Mvan_2921|M.vanbaalenii_PYR-1 -MCRLLGVASTLPVSVADAVGETVLTDFLALTKI---------HGDGWGV
MAB_0713|M.abscessus_ATCC_1997 MTAQPIELENDPREECGVFGVWAPGEEVAKLTYYG----LYALQHRGQEA
.: . . : : *
MMAR_4405|M.marinum_M G-VFDDRGRPELHKQPIAAWQDADFAAEAHEMTGTTFIAHVRYATAGS-H
MUL_0220|M.ulcerans_Agy99 G-VFDDRGRPELHKQPIAAWQDADFAAEAHEMTGTTFIAHVRYATAGS-H
Mb1090|M.bovis_AF2122/97 G-VFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGS-L
Rv1061|M.tuberculosis_H37Rv G-VFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGS-L
MAV_1188|M.avium_104 A-VFDEHARPQLHKEPIAAWRDAAFAREAHQLTGTTVIAHVRYATTGS-L
Mflv_2003|M.gilvum_PYR-GCK G-VFGADGKPTVLKQPIPAWRDTSFATEARQMTGTTFVAHVRYATTGA-T
MSMEG_6248|M.smegmatis_MC2_155 G-FFDDEGVARRWRSDKPLWGDASFASVAPALRSRCVLAAVRSATIGMPI
TH_0065|M.thermoresistible__bu G-FFDDDGVARRWRSATPLWGDASFASIAPVLRSGCVVAAVRSATVGMPI
Mvan_2921|M.vanbaalenii_PYR-1 ASAVGADDTPRVDVSADSALDDTRFGTAVKEP-ARGSVVHLRWATNGLAV
MAB_0713|M.abscessus_ATCC_1997 AGIAVADGSQIVVFKDLGLVSQVFDEQTLAAMRGHVAVGHCRYSTTGS-V
. . :. . : * :* *
MMAR_4405|M.marinum_M SVVNTHPFL-----QDGRIFAHNG--------------------------
MUL_0220|M.ulcerans_Agy99 SVVNTHPFL-----QDGRIFAHNG--------------------------
Mb1090|M.bovis_AF2122/97 DIRNTHPFL-----QDGRIFAHNG--------------------------
Rv1061|M.tuberculosis_H37Rv DIRNTHPFL-----QDGRIFAHNG--------------------------
MAV_1188|M.avium_104 DVRNTHPFL-----QDGRIFAHNG--------------------------
Mflv_2003|M.gilvum_PYR-GCK EEENTHPFL-----QDDRIFAHNG--------------------------
MSMEG_6248|M.smegmatis_MC2_155 EPSASAPFS-----DGQWLLSHNG--------------------------
TH_0065|M.thermoresistible__bu EPSASAPFT-----DGHWLLSHNG--------------------------
Mvan_2921|M.vanbaalenii_PYR-1 QPENSHPFA-----ADGVAMAHNG--------------------------
MAB_0713|M.abscessus_ATCC_1997 TWENAQPVFRTTAAGTGVALGHNGNLVNTAELTERARDAGLINSKTPGMA
: *. :.***
MMAR_4405|M.marinum_M -------------------------------------TLGDLELLDTRLR
MUL_0220|M.ulcerans_Agy99 -------------------------------------TLGDLELLDTRLR
Mb1090|M.bovis_AF2122/97 -------------------------------------VVEGLDVLDERLR
Rv1061|M.tuberculosis_H37Rv -------------------------------------VVEGLDVLDERLR
MAV_1188|M.avium_104 -------------------------------------VLEGLDVIDARLR
Mflv_2003|M.gilvum_PYR-GCK -------------------------------------VVEGLDILDARLS
MSMEG_6248|M.smegmatis_MC2_155 -------------------------------------LVD----------
TH_0065|M.thermoresistible__bu -------------------------------------RVD----------
Mvan_2921|M.vanbaalenii_PYR-1 -------------------------------------SIKPMAALDALLE
MAB_0713|M.abscessus_ATCC_1997 TTDSDIMGALLAHGAADATLEQAAMTLLPTVRGAFCLVFADENTLYAARD
.
MMAR_4405|M.marinum_M EVGTAGLVQGQTDSERVFALITAAIRTHDGDVSAGLLD-----------A
MUL_0220|M.ulcerans_Agy99 EVGTAGLVQGQTDSERVFALITAAIRTHDGGVSAGLLD-----------A
Mb1090|M.bovis_AF2122/97 EVGADDLVLGQTDSERVFALITASIRARDGNESAGLID-----------A
Rv1061|M.tuberculosis_H37Rv EVGADDLVLGQTDSERVFALITASIRARDGNESAGLID-----------A
MAV_1188|M.avium_104 EVGVDGLVLGDTDSERVFALITAAIRARDGDITAGLVD-----------A
Mflv_2003|M.gilvum_PYR-GCK ELGVTDLVHGDTDSERVFAVITASIRRRDGDVDAGLAD-----------A
MSMEG_6248|M.smegmatis_MC2_155 -RGVLPLTGA-AESTVDSAIVAALIFSRG---LDALGA-----------T
TH_0065|M.thermoresistible__bu -RAVLDTAAARAESTVDSALLAATIFERG---LDRLGE-----------T
Mvan_2921|M.vanbaalenii_PYR-1 PRVVS-TLRGTTDSERYFALIRQHRRSAP-DLVESVRR-----------A
MAB_0713|M.abscessus_ATCC_1997 PHGVRPLCLGRLDTGWVVASETAALDIVGASFVRDIEPGELLAIDADGVR
. . :: * :
MMAR_4405|M.marinum_M MGWLAANVPIYAVNVLLSTAT--GMWALRYPESHNLYILDRRNGAPAPRR
MUL_0220|M.ulcerans_Agy99 MGWLAANVPIYAVNVLLSTATGIGMWALRYPESHNLYILDRRNGAPASRR
Mb1090|M.bovis_AF2122/97 LRWLAANVPIYAVNVLLSTAT--DVWALRYPESHELYILDRR-GDGA--P
Rv1061|M.tuberculosis_H37Rv LRWLAANVPIYAVNVLLSTAT--DVWALRYPESHELYILDRR-GDGA--P
MAV_1188|M.avium_104 VRWLAEQVPIYAVNLLLSTAT--EMWALRYPHTHQLYVLDRS-ADAARQP
Mflv_2003|M.gilvum_PYR-GCK LHWLSTHVPIYALNILLATAT--DLWALRYPDTHELYLRDRAAGESG---
MSMEG_6248|M.smegmatis_MC2_155 IAEVGELDPNARLNILAANGS-----------------------------
TH_0065|M.thermoresistible__bu LRDVAAADPDARLNILAGNGT-----------------------------
Mvan_2921|M.vanbaalenii_PYR-1 VAELRQMYPEASLNALILGEG-----QLIAVHAHARSVLLDEDIEEISAT
MAB_0713|M.abscessus_ATCC_1997 SSRFANATPKTCVFEYVYLARPDSMLDGRSVHSTRVEIGRRLAAEHSVDA
. * :
MMAR_4405|M.marinum_M EFHLRTKRIRARSEH------------------------LRTRPSVVFAS
MUL_0220|M.ulcerans_Agy99 EFHLRTKRIRARSEH------------------------LRTRPSVVFAS
Mb1090|M.bovis_AF2122/97 EFHLRSKRIRAHSTH------------------------LRERSSVVFAT
Rv1061|M.tuberculosis_H37Rv EFHLRSKRIRAHSTH------------------------LRERSSVVFAT
MAV_1188|M.avium_104 EFDLHTIRIHARSQQ------------------------LRTRPSVVFAT
Mflv_2003|M.gilvum_PYR-GCK RFSLRSNRIRTGSAH------------------------LENSPSVVFAS
MSMEG_6248|M.smegmatis_MC2_155 --RLLATTWGDTLSV------------------------LHRPDGVVLAS
TH_0065|M.thermoresistible__bu --RLLATTWGDTLSV------------------------LAGDDGVVLAS
Mvan_2921|M.vanbaalenii_PYR-1 DLPVEHLEDYFSLRV------------------------ARPDDATVVIG
MAB_0713|M.abscessus_ATCC_1997 DLVIGVPESGTPAAVGYAQGSGIPYGQGLMKNAYVGRTFIQPSQTIRQLG
:
MMAR_4405|M.marinum_M QPMDDDPRWRLLDPGELVHVDVDLRITRSLALPDPPRHRLRLADLGPEVQ
MUL_0220|M.ulcerans_Agy99 QPMDDDPRWRLLDPGELVHVDVDLRITRSLALPDPPRHRLRLADLGPEVQ
Mb1090|M.bovis_AF2122/97 EPMDDNPRWRLLDAGELVHVDAALRVNRSLVLPDPPRHPIRREDLSEPVL
Rv1061|M.tuberculosis_H37Rv EPMDDNPRWRLLDAGELVHVDAALRVNRSLVLPDPPRHPIRREDLSEPVL
MAV_1188|M.avium_104 ERMDADPRWRLLEPGELVHVDAGLRVTRRLVLPDPPRQLLRRDELSTPVR
Mflv_2003|M.gilvum_PYR-GCK EAMDDG-AWQLLEAGEVIHVGPDLTIHRRMVLPEPPAHRMERSDLTAAAA
MSMEG_6248|M.smegmatis_MC2_155 EPYDDDPGWSDIPDRHLVDVRDAHVVVTPL--------------------
TH_0065|M.thermoresistible__bu EPYDDDPRWRDVPDRHLVEVTGAGVEMMALEGTA----------------
Mvan_2921|M.vanbaalenii_PYR-1 STGFGDLDWSPLPPESVASVALDDLSMTVVPIMAD---------------
MAB_0713|M.abscessus_ATCC_1997 IRLKLNPLREVIRGKRLVVVDDSIVRGNTQRALVRMLREAGAAEVHVRIA
. : : *
MMAR_4405|M.marinum_M EALHPPA-------------------------------------------
MUL_0220|M.ulcerans_Agy99 EALHPPA-------------------------------------------
Mb1090|M.bovis_AF2122/97 HAQHTSA-------------------------------------------
Rv1061|M.tuberculosis_H37Rv HAQHTSA-------------------------------------------
MAV_1188|M.avium_104 DSQHALPDTRRAG-------------------------------------
Mflv_2003|M.gilvum_PYR-GCK SAQHPMG-------------------------------------------
MSMEG_6248|M.smegmatis_MC2_155 --------------------------------------------------
TH_0065|M.thermoresistible__bu --------------------------------------------------
Mvan_2921|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0713|M.abscessus_ATCC_1997 SPPVRWPCFYGIDFASPAELIANAVESDDEMLDAVRTAIGADSLGYISAE
MMAR_4405|M.marinum_M --------------------------------------------------
MUL_0220|M.ulcerans_Agy99 --------------------------------------------------
Mb1090|M.bovis_AF2122/97 --------------------------------------------------
Rv1061|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1188|M.avium_104 --------------------------------------------------
Mflv_2003|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6248|M.smegmatis_MC2_155 --------------------------------------------------
TH_0065|M.thermoresistible__bu --------------------------------------------------
Mvan_2921|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0713|M.abscessus_ATCC_1997 GMVAATQEPRSRLCCACFDGNYPIELPKETALGKNVVEHMLAATARETSS
MMAR_4405|M.marinum_M ---------
MUL_0220|M.ulcerans_Agy99 ---------
Mb1090|M.bovis_AF2122/97 ---------
Rv1061|M.tuberculosis_H37Rv ---------
MAV_1188|M.avium_104 ---------
Mflv_2003|M.gilvum_PYR-GCK ---------
MSMEG_6248|M.smegmatis_MC2_155 ---------
TH_0065|M.thermoresistible__bu ---------
Mvan_2921|M.vanbaalenii_PYR-1 ---------
MAB_0713|M.abscessus_ATCC_1997 ESSESVQAR