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CRLFGLHAGRDCVTATFWLLNAPDSLAAQSKRNPDGTGLGVFDDRGRPELHKQPIAAWQDADFAAEAHEM TGTTFIAHVRYATAGSHSVVNTHPFLQDGRIFAHNGTLGDLELLDTRLREVGTAGLVQGQTDSERVFALI TAAIRTHDGGVSAGLLDAMGWLAANVPIYAVNVLLSTATGIGMWALRYPESHNLYILDRRNGAPASRREF HLRTKRIRARSEHLRTRPSVVFASQPMDDDPRWRLLDPGELVHVDVDLRITRSLALPDPPRHRLRLADLG PEVQEALHPPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0220 | - | - | 100% (292) | hypothetical protein MUL_0220 |
| M. ulcerans Agy99 | MUL_4286 | - | 6e-08 | 27.47% (273) | hypothetical protein MUL_4286 |
| M. ulcerans Agy99 | MUL_0872 | glmS | 4e-06 | 25.81% (155) | glucosamine--fructose-6-phosphate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1090 | - | 1e-122 | 74.40% (293) | hypothetical protein Mb1090 |
| M. gilvum PYR-GCK | Mflv_2003 | - | 3e-96 | 60.34% (290) | glutamine amidotransferase, class-II |
| M. tuberculosis H37Rv | Rv1061 | - | 1e-122 | 74.40% (293) | hypothetical protein Rv1061 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4405 | - | 1e-168 | 98.63% (292) | hypothetical protein MMAR_4405 |
| M. avium 104 | MAV_1188 | - | 1e-113 | 69.90% (289) | glutamine amidotransferase, class-II |
| M. smegmatis MC2 155 | MSMEG_6248 | - | 2e-09 | 28.05% (246) | hypothetical protein MSMEG_6248 |
| M. thermoresistible (build 8) | TH_0065 | - | 8e-10 | 28.25% (223) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_2921 | - | 1e-08 | 32.41% (145) | glutamine amidotransferase, class-II |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6248|M.smegmatis_MC2_155 MCRHVAWLGAPRSLAD--LVLDPPQGLLVQSYAPRRQKHGLMNADGWGAG
TH_0065|M.thermoresistible__bu MCRHLGWLGRPRSIAE--LMLEPPYGLLVQSYAPRRQKYGLLNADGWGVG
MUL_0220|M.ulcerans_Agy99 MCRLFGLHAGRDCVTATFWLLNAPDSLAAQSKR---------NPDGTGLG
MMAR_4405|M.marinum_M MCRLFGLHAGRDCVTATFWLLNAPDSLAAQSKR---------NPDGTGLG
Mb1090|M.bovis_AF2122/97 MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRR---------NPDGTGLG
Rv1061|M.tuberculosis_H37Rv MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRR---------NPDGTGLG
MAV_1188|M.avium_104 MCRLFGLHAGTRACTATFWLLDAPDSLAEQSRR---------NPDGTGLA
Mflv_2003|M.gilvum_PYR-GCK MCRLFGLHAG-RPVAATFWLLDAPNSLAQQSRR---------NPDGTGLG
Mvan_2921|M.vanbaalenii_PYR-1 MCRLLGVASTLPVSVADAVGETVLTDFLALTKI---------HGDGWGVA
*** .. . . .: : : ** * .
MSMEG_6248|M.smegmatis_MC2_155 -FFDDEGVARRWRSDKPLWGDASFASVAPALRSRCVLAAVRSATIGMPIE
TH_0065|M.thermoresistible__bu -FFDDDGVARRWRSATPLWGDASFASIAPVLRSGCVVAAVRSATVGMPIE
MUL_0220|M.ulcerans_Agy99 -VFDDRGRPELHKQPIAAWQDADFAAEAHEMTGTTFIAHVRYATAGS-HS
MMAR_4405|M.marinum_M -VFDDRGRPELHKQPIAAWQDADFAAEAHEMTGTTFIAHVRYATAGS-HS
Mb1090|M.bovis_AF2122/97 -VFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGS-LD
Rv1061|M.tuberculosis_H37Rv -VFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGS-LD
MAV_1188|M.avium_104 -VFDEHARPQLHKEPIAAWRDAAFAREAHQLTGTTVIAHVRYATTGS-LD
Mflv_2003|M.gilvum_PYR-GCK -VFGADGKPTVLKQPIPAWRDTSFATEARQMTGTTFVAHVRYATTGA-TE
Mvan_2921|M.vanbaalenii_PYR-1 SAVGADDTPRVDVSADSALDDTRFGTAVKEP-ARGSVVHLRWATNGLAVQ
.. . . . *: *. . . :. :* ** * .
MSMEG_6248|M.smegmatis_MC2_155 PSASAPFSDGQWLLSHNGLVD-----------RGVLPLTGA-AESTVDSA
TH_0065|M.thermoresistible__bu PSASAPFTDGHWLLSHNGRVD-----------RAVLDTAAARAESTVDSA
MUL_0220|M.ulcerans_Agy99 VVNTHPFLQDGRIFAHNGTLGDLELLDTRLREVGTAGLVQGQTDSERVFA
MMAR_4405|M.marinum_M VVNTHPFLQDGRIFAHNGTLGDLELLDTRLREVGTAGLVQGQTDSERVFA
Mb1090|M.bovis_AF2122/97 IRNTHPFLQDGRIFAHNGVVEGLDVLDERLREVGADDLVLGQTDSERVFA
Rv1061|M.tuberculosis_H37Rv IRNTHPFLQDGRIFAHNGVVEGLDVLDERLREVGADDLVLGQTDSERVFA
MAV_1188|M.avium_104 VRNTHPFLQDGRIFAHNGVLEGLDVIDARLREVGVDGLVLGDTDSERVFA
Mflv_2003|M.gilvum_PYR-GCK EENTHPFLQDDRIFAHNGVVEGLDILDARLSELGVTDLVHGDTDSERVFA
Mvan_2921|M.vanbaalenii_PYR-1 PENSHPFAADGVAMAHNGSIKPMAALDALLEPRVVS-TLRGTTDSERYFA
: ** . ::*** : . . ::* *
MSMEG_6248|M.smegmatis_MC2_155 IVAALIFSRG---LDALGATIAEVGELDPNARLNILAANGS---------
TH_0065|M.thermoresistible__bu LLAATIFERG---LDRLGETLRDVAAADPDARLNILAGNGT---------
MUL_0220|M.ulcerans_Agy99 LITAAIRTHDGGVSAGLLDAMGWLAANVPIYAVNVLLSTATGIGMWALRY
MMAR_4405|M.marinum_M LITAAIRTHDGDVSAGLLDAMGWLAANVPIYAVNVLLSTAT--GMWALRY
Mb1090|M.bovis_AF2122/97 LITASIRARDGNESAGLIDALRWLAANVPIYAVNVLLSTAT--DVWALRY
Rv1061|M.tuberculosis_H37Rv LITASIRARDGNESAGLIDALRWLAANVPIYAVNVLLSTAT--DVWALRY
MAV_1188|M.avium_104 LITAAIRARDGDITAGLVDAVRWLAEQVPIYAVNLLLSTAT--EMWALRY
Mflv_2003|M.gilvum_PYR-GCK VITASIRRRDGDVDAGLADALHWLSTHVPIYALNILLATAT--DLWALRY
Mvan_2921|M.vanbaalenii_PYR-1 LIRQHRRSAP-DLVESVRRAVAELRQMYPEASLNALILGEG---------
:: : :: : * :* *
MSMEG_6248|M.smegmatis_MC2_155 ----------------------RLLATTWGDTLSVLHRPDGVVLAS----
TH_0065|M.thermoresistible__bu ----------------------RLLATTWGDTLSVLAGDDGVVLAS----
MUL_0220|M.ulcerans_Agy99 PESHNLYILDRRNGAPASRREFHLRTKRIRARSEHLRTRPSVVFAS----
MMAR_4405|M.marinum_M PESHNLYILDRRNGAPAPRREFHLRTKRIRARSEHLRTRPSVVFAS----
Mb1090|M.bovis_AF2122/97 PESHELYILDRR-GDGA--PEFHLRSKRIRAHSTHLRERSSVVFAT----
Rv1061|M.tuberculosis_H37Rv PESHELYILDRR-GDGA--PEFHLRSKRIRAHSTHLRERSSVVFAT----
MAV_1188|M.avium_104 PHTHQLYVLDRS-ADAARQPEFDLHTIRIHARSQQLRTRPSVVFAT----
Mflv_2003|M.gilvum_PYR-GCK PDTHELYLRDRAAGESG---RFSLRSNRIRTGSAHLENSPSVVFAS----
Mvan_2921|M.vanbaalenii_PYR-1 ----------------------QLIAVHAHARSVLLDEDIEEISATDLPV
* : * : *:
MSMEG_6248|M.smegmatis_MC2_155 EPYDDDPGWSDIPDRHLVDVRDAHVVVTPL--------------------
TH_0065|M.thermoresistible__bu EPYDDDPRWRDVPDRHLVEVTGAGVEMMALEGTA----------------
MUL_0220|M.ulcerans_Agy99 QPMDDDPRWRLLDPGELVHVDVDLRITRSLALPDPPRHRLRLADLGPEVQ
MMAR_4405|M.marinum_M QPMDDDPRWRLLDPGELVHVDVDLRITRSLALPDPPRHRLRLADLGPEVQ
Mb1090|M.bovis_AF2122/97 EPMDDNPRWRLLDAGELVHVDAALRVNRSLVLPDPPRHPIRREDLSEPVL
Rv1061|M.tuberculosis_H37Rv EPMDDNPRWRLLDAGELVHVDAALRVNRSLVLPDPPRHPIRREDLSEPVL
MAV_1188|M.avium_104 ERMDADPRWRLLEPGELVHVDAGLRVTRRLVLPDPPRQLLRRDELSTPVR
Mflv_2003|M.gilvum_PYR-GCK EAMDDG-AWQLLEAGEVIHVGPDLTIHRRMVLPEPPAHRMERSDLTAAAA
Mvan_2921|M.vanbaalenii_PYR-1 EHLEDYFSLRVARPDDATVVIGSTGFG-DLDWSPLPPESVASVALDDLSM
: : . * :
MSMEG_6248|M.smegmatis_MC2_155 -------------
TH_0065|M.thermoresistible__bu -------------
MUL_0220|M.ulcerans_Agy99 EALHPPA------
MMAR_4405|M.marinum_M EALHPPA------
Mb1090|M.bovis_AF2122/97 HAQHTSA------
Rv1061|M.tuberculosis_H37Rv HAQHTSA------
MAV_1188|M.avium_104 DSQHALPDTRRAG
Mflv_2003|M.gilvum_PYR-GCK SAQHPMG------
Mvan_2921|M.vanbaalenii_PYR-1 TVVPIMAD-----