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MCRLFGLHAGTRACTATFWLLDAPDSLAEQSRRNPDGTGLAVFDEHARPQLHKEPIAAWRDAAFAREAHQ LTGTTVIAHVRYATTGSLDVRNTHPFLQDGRIFAHNGVLEGLDVIDARLREVGVDGLVLGDTDSERVFAL ITAAIRARDGDITAGLVDAVRWLAEQVPIYAVNLLLSTATEMWALRYPHTHQLYVLDRSADAARQPEFDL HTIRIHARSQQLRTRPSVVFATERMDADPRWRLLEPGELVHVDAGLRVTRRLVLPDPPRQLLRRDELSTP VRDSQHALPDTRRAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1188 | - | - | 100% (295) | glutamine amidotransferase, class-II |
| M. avium 104 | MAV_4377 | glmS | 6e-07 | 27.81% (169) | D-fructose-6-phosphate amidotransferase |
| M. avium 104 | MAV_0401 | - | 1e-06 | 25.76% (264) | hypothetical protein MAV_0401 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1090 | - | 1e-125 | 75.52% (286) | hypothetical protein Mb1090 |
| M. gilvum PYR-GCK | Mflv_2003 | - | 1e-100 | 61.46% (288) | glutamine amidotransferase, class-II |
| M. tuberculosis H37Rv | Rv1061 | - | 1e-125 | 75.52% (286) | hypothetical protein Rv1061 |
| M. leprae Br4923 | MLBr_00371 | glmS | 2e-06 | 25.58% (172) | glucosamine--fructose-6-phosphate aminotransferase |
| M. abscessus ATCC 19977 | MAB_3743c | - | 6e-10 | 31.72% (145) | glucosamine--fructose-6-phosphate aminotransferase |
| M. marinum M | MMAR_4405 | - | 1e-115 | 70.73% (287) | hypothetical protein MMAR_4405 |
| M. smegmatis MC2 155 | MSMEG_6248 | - | 8e-07 | 27.49% (251) | hypothetical protein MSMEG_6248 |
| M. thermoresistible (build 8) | TH_0065 | - | 9e-09 | 27.27% (264) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0220 | - | 1e-113 | 69.90% (289) | hypothetical protein MUL_0220 |
| M. vanbaalenii PYR-1 | Mvan_2921 | - | 7e-11 | 31.37% (204) | glutamine amidotransferase, class-II |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1090|M.bovis_AF2122/97 MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRR---------NPDGTGLG
Rv1061|M.tuberculosis_H37Rv MCRLFGLHSGTDAVTATFWLLNASDSLAEQSRR---------NPDGTGLG
MAV_1188|M.avium_104 MCRLFGLHAGTRACTATFWLLDAPDSLAEQSRR---------NPDGTGLA
MMAR_4405|M.marinum_M MCRLFGLHAGRDCVTATFWLLNAPDSLAAQSKR---------NPDGTGLG
MUL_0220|M.ulcerans_Agy99 MCRLFGLHAGRDCVTATFWLLNAPDSLAAQSKR---------NPDGTGLG
Mflv_2003|M.gilvum_PYR-GCK MCRLFGLHAG-RPVAATFWLLDAPNSLAQQSRR---------NPDGTGLG
MSMEG_6248|M.smegmatis_MC2_155 MCRHVAWLGAPRSLAD--LVLDPPQGLLVQSYAPRRQKHGLMNADGWGAG
TH_0065|M.thermoresistible__bu MCRHLGWLGRPRSIAE--LMLEPPYGLLVQSYAPRRQKYGLLNADGWGVG
MLBr_00371|M.leprae_Br4923 MCGLVGYVGQRPACGVVMDALRRMEYRGYDSSG----------IALINGS
MAB_3743c|M.abscessus_ATCC_199 MCGIVGYVGHRDALSVVLEALRRLEYRGYDSAG----------VALADG-
Mvan_2921|M.vanbaalenii_PYR-1 MCRLLGVASTLPVSVADAVGETVLTDFLALTKIHG--------DGWGVAS
** .. . :
Mb1090|M.bovis_AF2122/97 VFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGS-LDI
Rv1061|M.tuberculosis_H37Rv VFDEHHQPRLHKQPIAAWQDADFATEAHELTGTTFVAHVRYATTGS-LDI
MAV_1188|M.avium_104 VFDEHARPQLHKEPIAAWRDAAFAREAHQLTGTTVIAHVRYATTGS-LDV
MMAR_4405|M.marinum_M VFDDRGRPELHKQPIAAWQDADFAAEAHEMTGTTFIAHVRYATAGS-HSV
MUL_0220|M.ulcerans_Agy99 VFDDRGRPELHKQPIAAWQDADFAAEAHEMTGTTFIAHVRYATAGS-HSV
Mflv_2003|M.gilvum_PYR-GCK VFGADGKPTVLKQPIPAWRDTSFATEARQMTGTTFVAHVRYATTGA-TEE
MSMEG_6248|M.smegmatis_MC2_155 FFDDEGVARRWRSDKPLWGDASFASVAPALRSRCVLAAVRSATIGMPIEP
TH_0065|M.thermoresistible__bu FFDDDGVARRWRSATPLWGDASFASIAPVLRSGCVVAAVRSATVGMPIEP
MLBr_00371|M.leprae_Br4923 AKSGNLTVRRRAGRLSNLESVLAEMVPASLAGNVGLGHIRWATHGR-PTD
MAB_3743c|M.abscessus_ATCC_199 --HGGLLVQRKAGRLANLESAIAESG-ESFAATTGMGHTRWATHGA-PTD
Mvan_2921|M.vanbaalenii_PYR-1 AVGADDTPRVDVSADSALDDTRFGTAVKEPARG-SVVHLRWATNGLAVQP
. .. : * ** *
Mb1090|M.bovis_AF2122/97 RNTHPFLQDG--RIFAHNGVVEGLDVLDERLREVGADDLVLGQTDSERVF
Rv1061|M.tuberculosis_H37Rv RNTHPFLQDG--RIFAHNGVVEGLDVLDERLREVGADDLVLGQTDSERVF
MAV_1188|M.avium_104 RNTHPFLQDG--RIFAHNGVLEGLDVIDARLREVGVDGLVLGDTDSERVF
MMAR_4405|M.marinum_M VNTHPFLQDG--RIFAHNGTLGDLELLDTRLREVGTAGLVQGQTDSERVF
MUL_0220|M.ulcerans_Agy99 VNTHPFLQDG--RIFAHNGTLGDLELLDTRLREVGTAGLVQGQTDSERVF
Mflv_2003|M.gilvum_PYR-GCK ENTHPFLQDD--RIFAHNGVVEGLDILDARLSELGVTDLVHGDTDSERVF
MSMEG_6248|M.smegmatis_MC2_155 SASAPFSDGQ--WLLSHNGLVD-----------RGVLPLTGA-AESTVDS
TH_0065|M.thermoresistible__bu SASAPFTDGH--WLLSHNGRVD-----------RAVLDTAAARAESTVDS
MLBr_00371|M.leprae_Br4923 RNAHPHRDATGKIAVVHNGIIENFPSLRHELEIAGVEFVSDTDTEVAVHL
MAB_3743c|M.abscessus_ATCC_199 RNAHPHQDATGKVAVVHNGIIENFAVLRAELESAGVEFASDTDSEVAVHL
Mvan_2921|M.vanbaalenii_PYR-1 ENSHPFAADG--VAMAHNGSIKPMAALDALLEPRVVS-TLRGTTDSERYF
: *. . *** : . ::
Mb1090|M.bovis_AF2122/97 ALITASIRARDGNESAGLIDALRWLA------------------------
Rv1061|M.tuberculosis_H37Rv ALITASIRARDGNESAGLIDALRWLA------------------------
MAV_1188|M.avium_104 ALITAAIRARDGDITAGLVDAVRWLA------------------------
MMAR_4405|M.marinum_M ALITAAIRTHDGDVSAGLLDAMGWLA------------------------
MUL_0220|M.ulcerans_Agy99 ALITAAIRTHDGGVSAGLLDAMGWLA------------------------
Mflv_2003|M.gilvum_PYR-GCK AVITASIRRRDGDVDAGLADALHWLS------------------------
MSMEG_6248|M.smegmatis_MC2_155 AIVAALIFSRG---LDALGATIAEVG------------------------
TH_0065|M.thermoresistible__bu ALLAATIFERG---LDRLGETLRDVA------------------------
MLBr_00371|M.leprae_Br4923 VAQAYCAGETAGDFVGSVLAVLRRLQGHFTLVFANADEPGTIVAARRSTP
MAB_3743c|M.abscessus_ATCC_199 VSRQFESGDTAGDFVASVQSVVRRLEGHFTLVFSHADDPGTIVAARRSTP
Mvan_2921|M.vanbaalenii_PYR-1 ALIRQH-RRSAPDLVESVRRAVAELR------------------------
. : .: :
Mb1090|M.bovis_AF2122/97 --------------------------------------------------
Rv1061|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1188|M.avium_104 --------------------------------------------------
MMAR_4405|M.marinum_M --------------------------------------------------
MUL_0220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2003|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6248|M.smegmatis_MC2_155 --------------------------------------------------
TH_0065|M.thermoresistible__bu --------------------------------------------------
MLBr_00371|M.leprae_Br4923 LVLGIGDGEMFVGSDVAAFIEHTRQAVELGQDQAVVITADGYRISDFDGN
MAB_3743c|M.abscessus_ATCC_199 LVVGIGDGEMFLGSDVAAFIEYTRDAVELGQDQVVVITADGYRITDFEGN
Mvan_2921|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1090|M.bovis_AF2122/97 -------------------------------ANVPIYAVNVLLSTAT---
Rv1061|M.tuberculosis_H37Rv -------------------------------ANVPIYAVNVLLSTAT---
MAV_1188|M.avium_104 -------------------------------EQVPIYAVNLLLSTAT---
MMAR_4405|M.marinum_M -------------------------------ANVPIYAVNVLLSTAT---
MUL_0220|M.ulcerans_Agy99 -------------------------------ANVPIYAVNVLLSTATGI-
Mflv_2003|M.gilvum_PYR-GCK -------------------------------THVPIYALNILLATAT---
MSMEG_6248|M.smegmatis_MC2_155 -------------------------------ELDPNARLNILAANGS---
TH_0065|M.thermoresistible__bu -------------------------------AADPDARLNILAGNGT---
MLBr_00371|M.leprae_Br4923 DDAVNARTFHIDWDLAAAEKGGYEYFMLKEIAEQPDAVVDTLLGHFTGGR
MAB_3743c|M.abscessus_ATCC_199 DDTGNARVFTIDWDLSAAEKGGYEYFMLKEIAEQPAAVSDTLLGHFDLDR
Mvan_2921|M.vanbaalenii_PYR-1 -------------------------------QMYPEASLNALILGEG---
* : *
Mb1090|M.bovis_AF2122/97 ------------------DVWALRYPESHELYILDRR-GDGA--PEFHLR
Rv1061|M.tuberculosis_H37Rv ------------------DVWALRYPESHELYILDRR-GDGA--PEFHLR
MAV_1188|M.avium_104 ------------------EMWALRYPHTHQLYVLDRS-ADAARQPEFDLH
MMAR_4405|M.marinum_M ------------------GMWALRYPESHNLYILDRRNGAPAPRREFHLR
MUL_0220|M.ulcerans_Agy99 ------------------GMWALRYPESHNLYILDRRNGAPASRREFHLR
Mflv_2003|M.gilvum_PYR-GCK ------------------DLWALRYPDTHELYLRDRAAGESG---RFSLR
MSMEG_6248|M.smegmatis_MC2_155 -----------------------------------------------RLL
TH_0065|M.thermoresistible__bu -----------------------------------------------RLL
MLBr_00371|M.leprae_Br4923 IVLDEQRLSDQELREIDKVFVVACGTAYHSGLLAKYTIEHWTRLPVEVEL
MAB_3743c|M.abscessus_ATCC_199 IVLDEQRLSDQELRDIDKVFVVACGTAFHSGLLAKYAIEHWTRLPVEIEL
Mvan_2921|M.vanbaalenii_PYR-1 -------------------QLIAVHAHARSVLLDEDIEEISATDLPVEHL
Mb1090|M.bovis_AF2122/97 SKRIRAHSTHLRERSSVVFATEPMDDNPRWRLLDAGE-------------
Rv1061|M.tuberculosis_H37Rv SKRIRAHSTHLRERSSVVFATEPMDDNPRWRLLDAGE-------------
MAV_1188|M.avium_104 TIRIHARSQQLRTRPSVVFATERMDADPRWRLLEPGE-------------
MMAR_4405|M.marinum_M TKRIRARSEHLRTRPSVVFASQPMDDDPRWRLLDPGE-------------
MUL_0220|M.ulcerans_Agy99 TKRIRARSEHLRTRPSVVFASQPMDDDPRWRLLDPGE-------------
Mflv_2003|M.gilvum_PYR-GCK SNRIRTGSAHLENSPSVVFASEAMDDG-AWQLLEAGE-------------
MSMEG_6248|M.smegmatis_MC2_155 ATTWGDTLSVLHRPDGVVLASEPYDDDPGWSDIPDRH-------------
TH_0065|M.thermoresistible__bu ATTWGDTLSVLAGDDGVVLASEPYDDDPRWRDVPDRH-------------
MLBr_00371|M.leprae_Br4923 ASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAICNTN
MAB_3743c|M.abscessus_ATCC_199 ASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAVCNTN
Mvan_2921|M.vanbaalenii_PYR-1 EDYFSLR--VARPDDATVVIGSTGFGDLDWSPLPPES-------------
.* . :
Mb1090|M.bovis_AF2122/97 ----------------------------LVHVDAALRVNRSLVLPDPPRH
Rv1061|M.tuberculosis_H37Rv ----------------------------LVHVDAALRVNRSLVLPDPPRH
MAV_1188|M.avium_104 ----------------------------LVHVDAGLRVTRRLVLPDPPRQ
MMAR_4405|M.marinum_M ----------------------------LVHVDVDLRITRSLALPDPPRH
MUL_0220|M.ulcerans_Agy99 ----------------------------LVHVDVDLRITRSLALPDPPRH
Mflv_2003|M.gilvum_PYR-GCK ----------------------------VIHVGPDLTIHRRMVLPEPPAH
MSMEG_6248|M.smegmatis_MC2_155 ----------------------------LVDVRDAHVVVTPL--------
TH_0065|M.thermoresistible__bu ----------------------------LVEVTGAGVEMMALEGTA----
MLBr_00371|M.leprae_Br4923 GSQIPRECDAVLYTRAGPEIGVASTKTFLAQVAANYLLGLALAQARGTKY
MAB_3743c|M.abscessus_ATCC_199 GSQIPRECDAVLYTRAGPEIGVAATKTFLAQVTANYIVGLALAQARGTKY
Mvan_2921|M.vanbaalenii_PYR-1 ----------------------------VASVALDDLSMTVVPIMAD---
: * :
Mb1090|M.bovis_AF2122/97 PIRRE----------DLSEPVLHAQHTSA---------------------
Rv1061|M.tuberculosis_H37Rv PIRRE----------DLSEPVLHAQHTSA---------------------
MAV_1188|M.avium_104 LLRRD----------ELSTPVRDSQHALPDTRRAG---------------
MMAR_4405|M.marinum_M RLRLA----------DLGPEVQEALHPPA---------------------
MUL_0220|M.ulcerans_Agy99 RLRLA----------DLGPEVQEALHPPA---------------------
Mflv_2003|M.gilvum_PYR-GCK RMERS----------DLTAAAASAQHPMG---------------------
MSMEG_6248|M.smegmatis_MC2_155 --------------------------------------------------
TH_0065|M.thermoresistible__bu --------------------------------------------------
MLBr_00371|M.leprae_Br4923 PDEVQREYRELEAMPDLVARVIAGMGPVADLAYRFAQSTTVLFLGRHVGY
MAB_3743c|M.abscessus_ATCC_199 PDEVAREYHELEAMPELIERVISQMDPVADLARQYAQSSSILFLGRHVGY
Mvan_2921|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1090|M.bovis_AF2122/97 --------------------------------------------------
Rv1061|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1188|M.avium_104 --------------------------------------------------
MMAR_4405|M.marinum_M --------------------------------------------------
MUL_0220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2003|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6248|M.smegmatis_MC2_155 --------------------------------------------------
TH_0065|M.thermoresistible__bu --------------------------------------------------
MLBr_00371|M.leprae_Br4923 PVALEGALKLKELAYMHAEGFAAGELKHGPIALIEENLPVIVVMPSPKGS
MAB_3743c|M.abscessus_ATCC_199 PVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVIVVMPSPKGM
Mvan_2921|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1090|M.bovis_AF2122/97 --------------------------------------------------
Rv1061|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1188|M.avium_104 --------------------------------------------------
MMAR_4405|M.marinum_M --------------------------------------------------
MUL_0220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2003|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6248|M.smegmatis_MC2_155 --------------------------------------------------
TH_0065|M.thermoresistible__bu --------------------------------------------------
MLBr_00371|M.leprae_Br4923 AMLHAKLLSNIREIQTRGAVTIVIAEEGDDTVRLYADHLIELPAVSTLLQ
MAB_3743c|M.abscessus_ATCC_199 GLLHSKLLSNIREIQARGARTIVIAEEGDETIRPYADHLIEIPAVSTLYQ
Mvan_2921|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1090|M.bovis_AF2122/97 ------------------------------------
Rv1061|M.tuberculosis_H37Rv ------------------------------------
MAV_1188|M.avium_104 ------------------------------------
MMAR_4405|M.marinum_M ------------------------------------
MUL_0220|M.ulcerans_Agy99 ------------------------------------
Mflv_2003|M.gilvum_PYR-GCK ------------------------------------
MSMEG_6248|M.smegmatis_MC2_155 ------------------------------------
TH_0065|M.thermoresistible__bu ------------------------------------
MLBr_00371|M.leprae_Br4923 PLLSTIPLQVFAASVAQARGYDVDKPRNLAKSVTVE
MAB_3743c|M.abscessus_ATCC_199 PLLSTIPMQVFAAAVAQARGYDVDKPRNLAKSVTVE
Mvan_2921|M.vanbaalenii_PYR-1 ------------------------------------