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EIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDGNRRWARDAGYDDVSYGYRMGAAKIAEMLRW CQEAGIEMTTVYLLSTENLQRDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV ESTPATAQFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDAVSVEGISENLYTSGQPDPDLVIR TSGEQRLSGFLLWQSAYSEMWFTEAHWPAFRRVDFLRALRDYSMRHRRYGK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4380 | uppS | - | 100% (262) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
| M. marinum M | MMAR_3671 | - | 3e-33 | 35.17% (236) | long (C50) chain Z-isoprenyl diphosphate synthase |
| M. marinum M | MMAR_2589 | - | 7e-23 | 30.80% (237) | Z-decaprenyl diphosphate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1115 | - | 1e-139 | 91.98% (262) | short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP |
| M. gilvum PYR-GCK | Mflv_2055 | - | 1e-126 | 81.75% (263) | undecaprenyl diphosphate synthase |
| M. tuberculosis H37Rv | Rv1086 | - | 1e-139 | 91.60% (262) | short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP |
| M. leprae Br4923 | MLBr_02467 | - | 1e-140 | 92.37% (262) | putative undecaprenyl pyrophosphate synthetase |
| M. abscessus ATCC 19977 | MAB_1209 | - | 1e-119 | 77.48% (262) | short-chain Z-isoprenyl diphosphate synthetase |
| M. avium 104 | MAV_1211 | - | 1e-139 | 91.60% (262) | short-chain Z-isoprenyl diphosphate synthetase |
| M. smegmatis MC2 155 | MSMEG_5256 | uppS | 1e-130 | 85.93% (263) | undecaprenyl diphosphate synthase |
| M. thermoresistible (build 8) | TH_2165 | uppS | 1e-129 | 83.71% (264) | undecaprenyl diphosphate synthase |
| M. ulcerans Agy99 | MUL_0193 | uppS | 1e-150 | 100.00% (262) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
| M. vanbaalenii PYR-1 | Mvan_4662 | - | 1e-128 | 84.03% (263) | undecaprenyl diphosphate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2055|M.gilvum_PYR-GCK ---------MDLIPRRLKEPMYRLYEMRLRQGLSVKRSELPRHIAVLCDG
Mvan_4662|M.vanbaalenii_PYR-1 -------MIVDLIPRRLKEPMYRLYELRLRQGLTASRSELPRHIAVLCDG
Mb1115|M.bovis_AF2122/97 ---------MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDG
Rv1086|M.tuberculosis_H37Rv ---------MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDG
MMAR_4380|M.marinum_M ---------MEIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDG
MUL_0193|M.ulcerans_Agy99 MRVTVVWILVEIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDG
MLBr_02467|M.leprae_Br4923 ---------MEIIPPRLKEPLYALYELRLRQGLTASESRLPRHIAVLCDG
MAV_1211|M.avium_104 -------MFVEIIPPRLKEPLYRIYEMRLRQELGAAKADLPRHIAVLCDG
MSMEG_5256|M.smegmatis_MC2_155 ---------MDIIPPRLKEPAYRIYEMRLRHELVRSKAQLPRHIAVLCDG
TH_2165|M.thermoresistible__bu ---------VDIIPPRLKEPAYRLYEMRLRQELARSKSQLPRHIAVLCDG
MAB_1209|M.abscessus_ATCC_1997 ---------MEIIPPRLKEPLYKLYEMRLRQELVKASK--PRHIAVLCDG
:::** ***** * :**:***: * **********
Mflv_2055|M.gilvum_PYR-GCK NRRWARETGHDDVAYGYRVGAGKIAEMLRWCQEAGIEMATVYLLSTENLQ
Mvan_4662|M.vanbaalenii_PYR-1 NRRWARESGHDDVSYGYRAGARKIAEMLRWCQEAGIEMATVYLLSTENLQ
Mb1115|M.bovis_AF2122/97 NRRWARSAGYDDVSYGYRMGAAKIAEMLRWCHEAGIELATVYLLSTENLQ
Rv1086|M.tuberculosis_H37Rv NRRWARSAGYDDVSYGYRMGAAKIAEMLRWCHEAGIELATVYLLSTENLQ
MMAR_4380|M.marinum_M NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MUL_0193|M.ulcerans_Agy99 NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MLBr_02467|M.leprae_Br4923 NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MAV_1211|M.avium_104 NRRWARDAGYDDVSYGYRMGAVKIAEMLRWCQAAGIEMTTVYLLSTENLQ
MSMEG_5256|M.smegmatis_MC2_155 NRRWARDAGYDDVSIGYRKGAAKIAEMLRWCQAAGIEMATIYLLSTENLQ
TH_2165|M.thermoresistible__bu NRRWARDAGHDDVSYGYRKGAAKIAEMLRWCQDTGIELATIYLLSTENLQ
MAB_1209|M.abscessus_ATCC_1997 NRRWARSAGYTDVSHGYRMGARKISEMLGWCQDAGVEMATVYLLSAENLT
******.:*: **: *** ** **:*** **: :*:*::*:****:***
Mflv_2055|M.gilvum_PYR-GCK REPEELSCLIEIITEVVEEICAPANQWSVRTVGDLELIGEDQARRLRDAV
Mvan_4662|M.vanbaalenii_PYR-1 RDTEELSALIEIITEVVEEICAPANQWSVRTVGDLELIGEESARRLRDAV
Mb1115|M.bovis_AF2122/97 RDPDELAALIEIITDVVEEICAPANHWSVRTVGDLGLIGEEPARRLRGAV
Rv1086|M.tuberculosis_H37Rv RDPDELAALIEIITDVVEEICAPANHWSVRTVGDLGLIGEEPARRLRGAV
MMAR_4380|M.marinum_M RDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV
MUL_0193|M.ulcerans_Agy99 RDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV
MLBr_02467|M.leprae_Br4923 RDPDELAALIEIITDVVEEICAPANRWSVRTVGDLELLGEEPACRLRGAV
MAV_1211|M.avium_104 RDPDELAGLIEIITDVVEEICAPANRWSVRTVGDLELLGEEPARRLRGAV
MSMEG_5256|M.smegmatis_MC2_155 RDPDELTALIEIITDVVEEICAPYNKWSVRTVGDLELLGDEPARRLREAV
TH_2165|M.thermoresistible__bu RDPDELTALIEIITEVVEEICAPANKWSVRTVGDLALLGEEPARRLREAV
MAB_1209|M.abscessus_ATCC_1997 RDPDQLTELLEIITDVVEELCAPQNKWSVRSVGDLDLLPDEVAERMRQAV
*:.::*: *:****:****:*** *:****:**** *: :: * *:* **
Mflv_2055|M.gilvum_PYR-GCK SSTDGNG--GAFHVNVAVGYGGRQEIVDAVRALLSKELANGATGDQLVEA
Mvan_4662|M.vanbaalenii_PYR-1 SSTDGNG--GTFHVNVAVGYGGRQEIVDAVRALLSKELANGLTGEQLIES
Mb1115|M.bovis_AF2122/97 ESTP-EV--ASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDA
Rv1086|M.tuberculosis_H37Rv ESTP-EV--ASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDA
MMAR_4380|M.marinum_M ESTP-AT--AQFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDA
MUL_0193|M.ulcerans_Agy99 ESTP-AT--AQFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDA
MLBr_02467|M.leprae_Br4923 ESTP-GV--APFHVNVAVGYGGRREIVGAVRALLGKELANGATAEELVEA
MAV_1211|M.avium_104 ESTP-VE--ASFHVNVAVGYGGRREIVDAVRSLLSKELANGATAEELIDA
MSMEG_5256|M.smegmatis_MC2_155 ESTTTKG--ANFHVNVAVAYGGRQEIVDAVRSLLSKELANGATAEQLIEA
TH_2165|M.thermoresistible__bu DRTETVADAAAFHVNVAVGYGGRQEIVDAVRALLSKELANGASPEQLIQS
MAB_1209|M.abscessus_ATCC_1997 KSAPSDA---GFHVNVAVGYGGRQEITDAVRTLLNKELANGASAEQLVQA
. : *******.****:**..***:**.****** : ::*:::
Mflv_2055|M.gilvum_PYR-GCK VTAEAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAYW
Mvan_4662|M.vanbaalenii_PYR-1 VTAEAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAYW
Mb1115|M.bovis_AF2122/97 VTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
Rv1086|M.tuberculosis_H37Rv VTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MMAR_4380|M.marinum_M VSVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MUL_0193|M.ulcerans_Agy99 VSVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MLBr_02467|M.leprae_Br4923 VTVEGIARNLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTETHW
MAV_1211|M.avium_104 VTVDAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MSMEG_5256|M.smegmatis_MC2_155 VTVDGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAYW
TH_2165|M.thermoresistible__bu VTIDAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MAB_1209|M.abscessus_ATCC_1997 VTVDAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTDAYW
*: :.*:.**************************************:::*
Mflv_2055|M.gilvum_PYR-GCK PEFRRVDFLRALRDYSARHRRYGR
Mvan_4662|M.vanbaalenii_PYR-1 PEFRRVDFLRALRDYSARHRRYGR
Mb1115|M.bovis_AF2122/97 PAFRHVDFLRALRDYSARHRRYGR
Rv1086|M.tuberculosis_H37Rv PAFRHVDFLRALRDYSARHRSYGR
MMAR_4380|M.marinum_M PAFRRVDFLRALRDYSMRHRRYGK
MUL_0193|M.ulcerans_Agy99 PAFRRVDFLRALRDYSMRHRRYGK
MLBr_02467|M.leprae_Br4923 PAFRRVDFLRALRDYSMRHRRYGK
MAV_1211|M.avium_104 PAFRRVDFLRALRDYSQRHRRYGK
MSMEG_5256|M.smegmatis_MC2_155 PAFRRVDFLRALRDYTARHRRFGK
TH_2165|M.thermoresistible__bu PAFRRVDFLRALRDYTRRHRRFGM
MAB_1209|M.abscessus_ATCC_1997 PEFRRVDFLRALRDYAARNRRFGQ
* **:**********: *:* :*