For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TARRFPLNVAVCPDGNGRWAAQRGLSAMEGHLAGGEVAFNRVRDACELGLTQFSLYGFSTENWGRASAEV SGLMDIFSTLFDRGIQALEPLGIRLKVVGARVGLPHNVLDAIDRAEAATAHNDRMTLFVALNYGGRQEVL DAAERYTGGGPEAFHRLLYAPEMQDPDLVIRTGGDRRLSNGFLWESAYSELLFLDELWPDFTREHLENAL IEFGQRVRTLGTSHREQSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2589 | - | - | 100% (230) | Z-decaprenyl diphosphate synthase |
| M. marinum M | MMAR_3671 | - | 2e-42 | 40.43% (235) | long (C50) chain Z-isoprenyl diphosphate synthase |
| M. marinum M | MMAR_4380 | uppS | 6e-23 | 30.80% (237) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2382c | - | 9e-43 | 40.85% (235) | long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl |
| M. gilvum PYR-GCK | Mflv_2714 | - | 2e-40 | 38.77% (227) | undecaprenyl diphosphate synthase |
| M. tuberculosis H37Rv | Rv2361c | - | 9e-43 | 40.85% (235) | long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl |
| M. leprae Br4923 | MLBr_00634 | - | 2e-42 | 40.43% (235) | undecaprenyl pyrophosphate synthase |
| M. abscessus ATCC 19977 | MAB_1676 | - | 1e-36 | 36.68% (229) | undecaprenyl pyrophosphate synthetase |
| M. avium 104 | MAV_2034 | uppS | 2e-40 | 39.24% (237) | undecaprenyl diphosphate synthase |
| M. smegmatis MC2 155 | MSMEG_4490 | uppS | 1e-40 | 38.20% (233) | undecaprenyl diphosphate synthase |
| M. thermoresistible (build 8) | TH_0839 | - | 3e-40 | 39.06% (233) | LONG (C50) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-DECAPRENYL |
| M. ulcerans Agy99 | MUL_3171 | - | 1e-133 | 100.00% (230) | Z-decaprenyl diphosphate synthase |
| M. vanbaalenii PYR-1 | Mvan_3822 | - | 3e-40 | 38.77% (227) | undecaprenyl diphosphate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2382c|M.bovis_AF2122/97 MARDARK--RTSSNFPQLPPAPDDY-PTFPDTSTWPVVFPELPAAPYGGP
Rv2361c|M.tuberculosis_H37Rv MARDARK--RTSSNFPQLPPAPDDY-PTFPDTSTWPVVFPELPAAPYGGP
MAV_2034|M.avium_104 MVRAERA--PKSTGFPQLPPAPDDY-PVFPDKSTWPVVFPELPPSPGGGP
MLBr_00634|M.leprae_Br4923 MVRNERT--LKSTDFPQLPPAPDDY-PTFPDKSTWPVVFPMLPPSPDGGP
MSMEG_4490|M.smegmatis_MC2_155 ---MATT--RGKKTYPQLPPAPDDY-PTFPDKSTWPVVFPEIPAGTNGRF
Mvan_3822|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2714|M.gilvum_PYR-GCK --------------------------------------------------
TH_0839|M.thermoresistible__bu -------------VYPQLPAPPADY-PTFPDKSTWPVVFPELPPNTNGRF
MAB_1676|M.abscessus_ATCC_1997 MVKSSQPDPQQDKYYTDWADVPQGYNPTFPDKTVFPAVFPKLLPGVGPGG
MMAR_2589|M.marinum_M --------------------------------------------------
MUL_3171|M.ulcerans_Agy99 --------------------------------------------------
Mb2382c|M.bovis_AF2122/97 CRP---PQHTSKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHK
Rv2361c|M.tuberculosis_H37Rv CRP---PQHTSKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHK
MAV_2034|M.avium_104 SRP---PQHISKAAAPRIPADRLPNHVAIVMDGNGRWATERGMSRTDGHK
MLBr_00634|M.leprae_Br4923 RRP---PQHTSKAVAPRLSAAQLPTHVAIVMDGNGRWANQRGLHRTEGHK
MSMEG_4490|M.smegmatis_MC2_155 ARP---PQHTSKAAAPKIPADQVPNHVAVVMDGNGRWATQRGLGRTEGHK
Mvan_3822|M.vanbaalenii_PYR-1 ----------------------MPNHVAVVMDGNGRWATQRGLGRTEGHK
Mflv_2714|M.gilvum_PYR-GCK ----------------------MPQHVAVVMDGNGRWATQRGLGRTEGHK
TH_0839|M.thermoresistible__bu ARP---PQHPSRAVAPRIPADQVPNHVAVVMDGNGRWATQRGLHRTEGHK
MAB_1676|M.abscessus_ATCC_1997 TRPHPAPKHPSGAVPPAIPKELIPRHVAVVMDGNGRWARARGLPRTEGHK
MMAR_2589|M.marinum_M -----------------MTARRFPLNVAVCPDGNGRWAAQRGLSAMEGHL
MUL_3171|M.ulcerans_Agy99 -----------------MTARRFPLNVAVCPDGNGRWAAQRGLSAMEGHL
.* :**: ******* **: :**
Mb2382c|M.bovis_AF2122/97 MGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR
Rv2361c|M.tuberculosis_H37Rv MGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR
MAV_2034|M.avium_104 AGEAVVIDIVCGAIEIGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR
MLBr_00634|M.leprae_Br4923 MGEAVVIDVACGAIELGIKWLSLYAFSTENWKRSVEEVRFLMGFNRDVVR
MSMEG_4490|M.smegmatis_MC2_155 MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSTEEVRFLMGFNREVVR
Mvan_3822|M.vanbaalenii_PYR-1 MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSTEEVRFLMGFNREVVR
Mflv_2714|M.gilvum_PYR-GCK MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSTEEVRFLMGFNREVVR
TH_0839|M.thermoresistible__bu MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSPEEVRFLMGFNREVVR
MAB_1676|M.abscessus_ATCC_1997 MGEATMMDMVCGAIEMGIPWLTTYAFSTENWRRPADEVRFLMGFNRDVVK
MMAR_2589|M.marinum_M AGGEVAFNRVRDACELGLTQFSLYGFSTENWGRASAEVSGLMDIFSTLFD
MUL_3171|M.ulcerans_Agy99 AGGEVAFNRVRDACELGLTQFSLYGFSTENWGRASAEVSGLMDIFSTLFD
* . :: . .* *:*: :: *.****** *. ** **.: :.
Mb2382c|M.bovis_AF2122/97 RRRDTLKKLGVRIRWVGSRPRLWRSVINELAVAEEMTKSNDVITINYCVN
Rv2361c|M.tuberculosis_H37Rv RRRDTLKKLGVRIRWVGSRPRLWRSVINELAVAEEMTKSNDVITINYCVN
MAV_2034|M.avium_104 MRRVNLNTIGVKIRWVGSRPRLWRSVINELAIAEEMTKRNDVITVNYCVN
MLBr_00634|M.leprae_Br4923 RRRENLKEMGVRIRWVGSRPRLWRSVINELAIAEHMTAGNDVITINYCVN
MSMEG_4490|M.smegmatis_MC2_155 RRRENLNDMGVRMRWVGSRPRMWRSVIKEFDIAEQMTVDNDVITINYCVN
Mvan_3822|M.vanbaalenii_PYR-1 RRRENLNDMGVRMRWVGSRPRMWRSVIKEFDIAEQMTVDNDVITINYCVN
Mflv_2714|M.gilvum_PYR-GCK RRRENLNDMGVRMRWVGSRPRMWSSVIKEFDIAEQMTVDNDVITINYCVN
TH_0839|M.thermoresistible__bu RRRENLNDMGVKMRWVGSRPRMWRSVIKEFEIAENMTLDNDVITINYCVN
MAB_1676|M.abscessus_ATCC_1997 RRRHDLNNMGVRFRWAGQKTRLWSSVYKELEITEELTKNNSTLTLTTCIN
MMAR_2589|M.marinum_M RGIQALEPLGIRLKVVGARVGLPHNVLDAIDRAEAATAHNDRMTLFVALN
MUL_3171|M.ulcerans_Agy99 RGIQALEPLGIRLKVVGARVGLPHNVLDAIDRAEAATAHNDRMTLFVALN
*: :*:::: .* : : .* . : :* * *. :*: .:*
Mb2382c|M.bovis_AF2122/97 YGGRTEITEATREIAREVAAGRLNPERITESTIARHLQRPDIPDVDLFLR
Rv2361c|M.tuberculosis_H37Rv YGGRTEITEATREIAREVAAGRLNPERITESTIARHLQRPDIPDVDLFLR
MAV_2034|M.avium_104 YGGRAEIAEATKEIARLAAAGRLNPERITESTVAHHLQRPDIPDVDLFLR
MLBr_00634|M.leprae_Br4923 YGGRTEIAEATREIARLAAAGRLNPERITESTITRHLQRPDIPDVDLFVR
MSMEG_4490|M.smegmatis_MC2_155 YGGRTEIVEAARALAQEAVDGKINPARISEAMFAKHLHRADIPDVDLFIR
Mvan_3822|M.vanbaalenii_PYR-1 YGGRTEIVEAARELAQQAVDGKINPARITEATFAKHLHRADIPDVDLFIR
Mflv_2714|M.gilvum_PYR-GCK YGGRTEIVEAARELAQQAVDGKIKPNRITEAQFAKHLHRSDIPDVDLFIR
TH_0839|M.thermoresistible__bu YGGRAEITEAARSIAKEAVAGRINPDRITEKTVARHLHRPDIPDVDLFIR
MAB_1676|M.abscessus_ATCC_1997 YGGRAEIAEATRRIARLVESGQLKPDRITEETIAKYLDEPDMPDVDLFLR
MMAR_2589|M.marinum_M YGGRQEVLDAA---ERYTGGG---PE-----AFHRLLYAPEMQDPDLVIR
MUL_3171|M.ulcerans_Agy99 YGGRQEVLDAA---ERYTGGG---PE-----AFHRLLYAPEMQDPDLVIR
**** *: :*: : . * * . : * .:: * **.:*
Mb2382c|M.bovis_AF2122/97 TSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRTRRFG
Rv2361c|M.tuberculosis_H37Rv TSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRTRRFG
MAV_2034|M.avium_104 TSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACQEYASRNRRFG
MLBr_00634|M.leprae_Br4923 TSGEQRSSNFMLWQAAYTEYIFQDKLWPDYDRRDLWAACEEYASRNRRFG
MSMEG_4490|M.smegmatis_MC2_155 TSGEQRASNFLLWQAAYAEYVFQDKLWPDYDRRDLWAACEEYVNRNRRFG
Mvan_3822|M.vanbaalenii_PYR-1 TSGEQRASNFLLWQAAYAEYVFQDKLWPDYDRRDLWAACEEYVNRNRRFG
Mflv_2714|M.gilvum_PYR-GCK TSGEQRASNFLLWQAAYAEYVFQDKLWPDYDRRDLWAACEEYVHRNRRFG
TH_0839|M.thermoresistible__bu TSGEQRASNFLLWQSAYAEFVFQDKLWPDYDRRDLWAACEEYVRRNRRFG
MAB_1676|M.abscessus_ATCC_1997 PSGEFRSSNFMMWQSAYAEFVFQEKMYPDFDRRDLWAACLEYAQRDRRFG
MMAR_2589|M.marinum_M TGGDRRLSNGFLWESAYSELLFLDELWPDFTREHLENALIEFGQRVRTLG
MUL_3171|M.ulcerans_Agy99 TGGDRRLSNGFLWESAYSELLFLDELWPDFTREHLENALIEFGQRVRTLG
..*: * ** ::*::**:* :* ::::**: *..* * *: * * :*
Mb2382c|M.bovis_AF2122/97 SA------
Rv2361c|M.tuberculosis_H37Rv SA------
MAV_2034|M.avium_104 SA------
MLBr_00634|M.leprae_Br4923 SA------
MSMEG_4490|M.smegmatis_MC2_155 RA------
Mvan_3822|M.vanbaalenii_PYR-1 RAE-----
Mflv_2714|M.gilvum_PYR-GCK RA------
TH_0839|M.thermoresistible__bu RA------
MAB_1676|M.abscessus_ATCC_1997 SA------
MMAR_2589|M.marinum_M TSHREQSP
MUL_3171|M.ulcerans_Agy99 TSHREQSP
: