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VEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDGNRRWARSAGYDDVSYGYRMGAAKIAEMLR WCHEAGIELATVYLLSTENLQRDPDELAALIEIITDVVEEICAPANHWSVRTVGDLGLIGEEPARRLRGA VESTPEVASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDAVTVEGISENLYTSGQPDPDLVI RTSGEQRLSGFLLWQSAYSEMWFTEAHWPAFRHVDFLRALRDYSARHRSYGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1086 | - | - | 100% (262) | SHORT (C15) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-FPP SYNTHASE) (Z-FARNESYL DIPHOSPHATE SYNTHASE) (Z-FPP SYNTHETASE) (Z-FARNESYL DIPHOSPHATE SYNTHETASE) (GERANYLTRANSTRANSFERASE) (FARNESYL PYROPHOSPHATE SYNTHETASE) |
| M. tuberculosis H37Rv | Rv2361c | - | 9e-32 | 35.62% (233) | long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl |
| M. tuberculosis H37Rv | Rv1087A | - | 3e-13 | 47.12% (104) | hypothetical protein Rv1087A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1115 | - | 1e-151 | 99.62% (262) | short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP |
| M. gilvum PYR-GCK | Mflv_2055 | - | 1e-126 | 82.51% (263) | undecaprenyl diphosphate synthase |
| M. leprae Br4923 | MLBr_02467 | - | 1e-137 | 90.84% (262) | putative undecaprenyl pyrophosphate synthetase |
| M. abscessus ATCC 19977 | MAB_1209 | - | 1e-118 | 77.48% (262) | short-chain Z-isoprenyl diphosphate synthetase |
| M. marinum M | MMAR_4380 | uppS | 1e-139 | 91.60% (262) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
| M. avium 104 | MAV_1211 | - | 1e-137 | 90.08% (262) | short-chain Z-isoprenyl diphosphate synthetase |
| M. smegmatis MC2 155 | MSMEG_5256 | uppS | 1e-127 | 84.03% (263) | undecaprenyl diphosphate synthase |
| M. thermoresistible (build 8) | TH_2165 | uppS | 1e-128 | 84.09% (264) | undecaprenyl diphosphate synthase |
| M. ulcerans Agy99 | MUL_0193 | uppS | 1e-139 | 91.60% (262) | short (C15) chain Z-isoprenyl diphosphate synthase, UppS |
| M. vanbaalenii PYR-1 | Mvan_4662 | - | 1e-126 | 84.03% (263) | undecaprenyl diphosphate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2055|M.gilvum_PYR-GCK ---------MDLIPRRLKEPMYRLYEMRLRQGLSVKRSELPRHIAVLCDG
Mvan_4662|M.vanbaalenii_PYR-1 -------MIVDLIPRRLKEPMYRLYELRLRQGLTASRSELPRHIAVLCDG
Rv1086|M.tuberculosis_H37Rv ---------MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDG
Mb1115|M.bovis_AF2122/97 ---------MEIIPPRLKEPLYRLYELRLRQGLAASKSDLPRHIAVLCDG
MMAR_4380|M.marinum_M ---------MEIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDG
MUL_0193|M.ulcerans_Agy99 MRVTVVWILVEIIPPRLKEPLYRLYELRLRQGLAATSSELPRHIAVLCDG
MLBr_02467|M.leprae_Br4923 ---------MEIIPPRLKEPLYALYELRLRQGLTASESRLPRHIAVLCDG
MAV_1211|M.avium_104 -------MFVEIIPPRLKEPLYRIYEMRLRQELGAAKADLPRHIAVLCDG
MSMEG_5256|M.smegmatis_MC2_155 ---------MDIIPPRLKEPAYRIYEMRLRHELVRSKAQLPRHIAVLCDG
TH_2165|M.thermoresistible__bu ---------VDIIPPRLKEPAYRLYEMRLRQELARSKSQLPRHIAVLCDG
MAB_1209|M.abscessus_ATCC_1997 ---------MEIIPPRLKEPLYKLYEMRLRQELVKASK--PRHIAVLCDG
:::** ***** * :**:***: * **********
Mflv_2055|M.gilvum_PYR-GCK NRRWARETGHDDVAYGYRVGAGKIAEMLRWCQEAGIEMATVYLLSTENLQ
Mvan_4662|M.vanbaalenii_PYR-1 NRRWARESGHDDVSYGYRAGARKIAEMLRWCQEAGIEMATVYLLSTENLQ
Rv1086|M.tuberculosis_H37Rv NRRWARSAGYDDVSYGYRMGAAKIAEMLRWCHEAGIELATVYLLSTENLQ
Mb1115|M.bovis_AF2122/97 NRRWARSAGYDDVSYGYRMGAAKIAEMLRWCHEAGIELATVYLLSTENLQ
MMAR_4380|M.marinum_M NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MUL_0193|M.ulcerans_Agy99 NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MLBr_02467|M.leprae_Br4923 NRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQ
MAV_1211|M.avium_104 NRRWARDAGYDDVSYGYRMGAVKIAEMLRWCQAAGIEMTTVYLLSTENLQ
MSMEG_5256|M.smegmatis_MC2_155 NRRWARDAGYDDVSIGYRKGAAKIAEMLRWCQAAGIEMATIYLLSTENLQ
TH_2165|M.thermoresistible__bu NRRWARDAGHDDVSYGYRKGAAKIAEMLRWCQDTGIELATIYLLSTENLQ
MAB_1209|M.abscessus_ATCC_1997 NRRWARSAGYTDVSHGYRMGARKISEMLGWCQDAGVEMATVYLLSAENLT
******.:*: **: *** ** **:*** **: :*:*::*:****:***
Mflv_2055|M.gilvum_PYR-GCK REPEELSCLIEIITEVVEEICAPANQWSVRTVGDLELIGEDQARRLRDAV
Mvan_4662|M.vanbaalenii_PYR-1 RDTEELSALIEIITEVVEEICAPANQWSVRTVGDLELIGEESARRLRDAV
Rv1086|M.tuberculosis_H37Rv RDPDELAALIEIITDVVEEICAPANHWSVRTVGDLGLIGEEPARRLRGAV
Mb1115|M.bovis_AF2122/97 RDPDELAALIEIITDVVEEICAPANHWSVRTVGDLGLIGEEPARRLRGAV
MMAR_4380|M.marinum_M RDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV
MUL_0193|M.ulcerans_Agy99 RDADELAALIEIITDVVEEICAPANRWSVRTVGDLELLGDEPARRLREAV
MLBr_02467|M.leprae_Br4923 RDPDELAALIEIITDVVEEICAPANRWSVRTVGDLELLGEEPACRLRGAV
MAV_1211|M.avium_104 RDPDELAGLIEIITDVVEEICAPANRWSVRTVGDLELLGEEPARRLRGAV
MSMEG_5256|M.smegmatis_MC2_155 RDPDELTALIEIITDVVEEICAPYNKWSVRTVGDLELLGDEPARRLREAV
TH_2165|M.thermoresistible__bu RDPDELTALIEIITEVVEEICAPANKWSVRTVGDLALLGEEPARRLREAV
MAB_1209|M.abscessus_ATCC_1997 RDPDQLTELLEIITDVVEELCAPQNKWSVRSVGDLDLLPDEVAERMRQAV
*:.::*: *:****:****:*** *:****:**** *: :: * *:* **
Mflv_2055|M.gilvum_PYR-GCK SSTDGNG--GAFHVNVAVGYGGRQEIVDAVRALLSKELANGATGDQLVEA
Mvan_4662|M.vanbaalenii_PYR-1 SSTDGNG--GTFHVNVAVGYGGRQEIVDAVRALLSKELANGLTGEQLIES
Rv1086|M.tuberculosis_H37Rv ESTP-EV--ASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDA
Mb1115|M.bovis_AF2122/97 ESTP-EV--ASFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELVDA
MMAR_4380|M.marinum_M ESTP-AT--AQFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDA
MUL_0193|M.ulcerans_Agy99 ESTP-AT--AQFHVNVAVGYGGRREIVDAVRALLSKELANGATAEELIDA
MLBr_02467|M.leprae_Br4923 ESTP-GV--APFHVNVAVGYGGRREIVGAVRALLGKELANGATAEELVEA
MAV_1211|M.avium_104 ESTP-VE--ASFHVNVAVGYGGRREIVDAVRSLLSKELANGATAEELIDA
MSMEG_5256|M.smegmatis_MC2_155 ESTTTKG--ANFHVNVAVAYGGRQEIVDAVRSLLSKELANGATAEQLIEA
TH_2165|M.thermoresistible__bu DRTETVADAAAFHVNVAVGYGGRQEIVDAVRALLSKELANGASPEQLIQS
MAB_1209|M.abscessus_ATCC_1997 KSAPSDA---GFHVNVAVGYGGRQEITDAVRTLLNKELANGASAEQLVQA
. : *******.****:**..***:**.****** : ::*:::
Mflv_2055|M.gilvum_PYR-GCK VTAEAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAYW
Mvan_4662|M.vanbaalenii_PYR-1 VTAEAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAYW
Rv1086|M.tuberculosis_H37Rv VTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
Mb1115|M.bovis_AF2122/97 VTVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MMAR_4380|M.marinum_M VSVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MUL_0193|M.ulcerans_Agy99 VSVEGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MLBr_02467|M.leprae_Br4923 VTVEGIARNLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTETHW
MAV_1211|M.avium_104 VTVDAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MSMEG_5256|M.smegmatis_MC2_155 VTVDGISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAYW
TH_2165|M.thermoresistible__bu VTIDAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTEAHW
MAB_1209|M.abscessus_ATCC_1997 VTVDAISENLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTDAYW
*: :.*:.**************************************:::*
Mflv_2055|M.gilvum_PYR-GCK PEFRRVDFLRALRDYSARHRRYGR
Mvan_4662|M.vanbaalenii_PYR-1 PEFRRVDFLRALRDYSARHRRYGR
Rv1086|M.tuberculosis_H37Rv PAFRHVDFLRALRDYSARHRSYGR
Mb1115|M.bovis_AF2122/97 PAFRHVDFLRALRDYSARHRRYGR
MMAR_4380|M.marinum_M PAFRRVDFLRALRDYSMRHRRYGK
MUL_0193|M.ulcerans_Agy99 PAFRRVDFLRALRDYSMRHRRYGK
MLBr_02467|M.leprae_Br4923 PAFRRVDFLRALRDYSMRHRRYGK
MAV_1211|M.avium_104 PAFRRVDFLRALRDYSQRHRRYGK
MSMEG_5256|M.smegmatis_MC2_155 PAFRRVDFLRALRDYTARHRRFGK
TH_2165|M.thermoresistible__bu PAFRRVDFLRALRDYTRRHRRFGM
MAB_1209|M.abscessus_ATCC_1997 PEFRRVDFLRALRDYAARNRRFGQ
* **:**********: *:* :*