For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_3671 (-)

annotation: long (C50) chain Z-isoprenyl diphosphate synthase
coordinates: 4518808 - 4519698
length: 296

AKSARRLKSADFPQLPQAPDDYPTFPDTSSWPVVFPELPPSPDGGPRRPPQHISKTAAPRIPADRLPNHV
AIVMDGNGRWATERGLRRTEGHKMGEAVVIDIACGAVELGIKWLSLYAFSTENWKRSAEEVRFLMGFNRD
VVRRRRDVLNQMGVRIRWVGSRPRLWRSVINELAVAEAMTNNNDVITINYCVNYGGRTEIAEATRDIARE
VAAGRLNPERITESTIARHMQRPDIPDVDLFLRTSGEQRSSNFMLWQSAYAEYIFQDKLWPDYDRRDLWA
ACEEYASRNRRFGSA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3671--100% (296)long (C50) chain Z-isoprenyl diphosphate synthase
M. marinum MMMAR_2589-3e-4240.43% (235) Z-decaprenyl diphosphate synthase
M. marinum MMMAR_4380uppS4e-3335.17% (236) short (C15) chain Z-isoprenyl diphosphate synthase, UppS

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2382c-1e-15989.53% (296) long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl
M. gilvum PYR-GCKMflv_2714-1e-10876.09% (230) undecaprenyl diphosphate synthase
M. tuberculosis H37RvRv2361c-1e-15989.53% (296) long (C50) chain Z-isoprenyl diphosphate synthase (Z-decaprenyl
M. leprae Br4923MLBr_00634-1e-15586.49% (296) undecaprenyl pyrophosphate synthase
M. abscessus ATCC 19977MAB_1676-1e-10863.19% (288) undecaprenyl pyrophosphate synthetase
M. avium 104MAV_2034uppS1e-15385.14% (296) undecaprenyl diphosphate synthase
M. smegmatis MC2 155MSMEG_4490uppS1e-13576.06% (284) undecaprenyl diphosphate synthase
M. thermoresistible (build 8)TH_0839-1e-13777.46% (284) LONG (C50) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-DECAPRENYL
M. ulcerans Agy99MUL_3614-1e-176100.00% (296) long (C50) chain Z-isoprenyl diphosphate synthase
M. vanbaalenii PYR-1Mvan_3822-1e-11077.83% (230) undecaprenyl diphosphate synthase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4490|M.smegmatis_MC2_155      ---MATT--RGKKTYPQLPPAPDDY-PTFPDKSTWPVVFPEIPAGTNGRF
Mvan_3822|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_2714|M.gilvum_PYR-GCK          --------------------------------------------------
TH_0839|M.thermoresistible__bu      -------------VYPQLPAPPADY-PTFPDKSTWPVVFPELPPNTNGRF
MMAR_3671|M.marinum_M               MAKSARR--LKSADFPQLPQAPDDY-PTFPDTSSWPVVFPELPPSPDGGP
MUL_3614|M.ulcerans_Agy99           MAKSARR--LKSADFPQLPQAPDDY-PTFPDTSSWPVVFPELPPSPDGGP
Mb2382c|M.bovis_AF2122/97           MARDARK--RTSSNFPQLPPAPDDY-PTFPDTSTWPVVFPELPAAPYGGP
Rv2361c|M.tuberculosis_H37Rv        MARDARK--RTSSNFPQLPPAPDDY-PTFPDTSTWPVVFPELPAAPYGGP
MLBr_00634|M.leprae_Br4923          MVRNERT--LKSTDFPQLPPAPDDY-PTFPDKSTWPVVFPMLPPSPDGGP
MAV_2034|M.avium_104                MVRAERA--PKSTGFPQLPPAPDDY-PVFPDKSTWPVVFPELPPSPGGGP
MAB_1676|M.abscessus_ATCC_1997      MVKSSQPDPQQDKYYTDWADVPQGYNPTFPDKTVFPAVFPKLLPGVGPGG
                                                                                      

MSMEG_4490|M.smegmatis_MC2_155      ARP---PQHTSKAAAPKIPADQVPNHVAVVMDGNGRWATQRGLGRTEGHK
Mvan_3822|M.vanbaalenii_PYR-1       ----------------------MPNHVAVVMDGNGRWATQRGLGRTEGHK
Mflv_2714|M.gilvum_PYR-GCK          ----------------------MPQHVAVVMDGNGRWATQRGLGRTEGHK
TH_0839|M.thermoresistible__bu      ARP---PQHPSRAVAPRIPADQVPNHVAVVMDGNGRWATQRGLHRTEGHK
MMAR_3671|M.marinum_M               RRP---PQHISKTAAPRIPADRLPNHVAIVMDGNGRWATERGLRRTEGHK
MUL_3614|M.ulcerans_Agy99           RRP---PQHISKTAAPRIPADRLPNHVAIVMDGNGRWATERGLRRTEGHK
Mb2382c|M.bovis_AF2122/97           CRP---PQHTSKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHK
Rv2361c|M.tuberculosis_H37Rv        CRP---PQHTSKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHK
MLBr_00634|M.leprae_Br4923          RRP---PQHTSKAVAPRLSAAQLPTHVAIVMDGNGRWANQRGLHRTEGHK
MAV_2034|M.avium_104                SRP---PQHISKAAAPRIPADRLPNHVAIVMDGNGRWATERGMSRTDGHK
MAB_1676|M.abscessus_ATCC_1997      TRPHPAPKHPSGAVPPAIPKELIPRHVAVVMDGNGRWARARGLPRTEGHK
                                                          :* ***:*********  **: **:***

MSMEG_4490|M.smegmatis_MC2_155      MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSTEEVRFLMGFNREVVR
Mvan_3822|M.vanbaalenii_PYR-1       MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSTEEVRFLMGFNREVVR
Mflv_2714|M.gilvum_PYR-GCK          MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSTEEVRFLMGFNREVVR
TH_0839|M.thermoresistible__bu      MGEAVLIDITCGAIEIGIKHLTVYAFSTENWKRSPEEVRFLMGFNREVVR
MMAR_3671|M.marinum_M               MGEAVVIDIACGAVELGIKWLSLYAFSTENWKRSAEEVRFLMGFNRDVVR
MUL_3614|M.ulcerans_Agy99           MGEAVVIDIACGAVELGIKWLSLYAFSTENWKRSAEEVRFLMGFNRDVVR
Mb2382c|M.bovis_AF2122/97           MGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR
Rv2361c|M.tuberculosis_H37Rv        MGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR
MLBr_00634|M.leprae_Br4923          MGEAVVIDVACGAIELGIKWLSLYAFSTENWKRSVEEVRFLMGFNRDVVR
MAV_2034|M.avium_104                AGEAVVIDIVCGAIEIGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR
MAB_1676|M.abscessus_ATCC_1997      MGEATMMDMVCGAIEMGIPWLTTYAFSTENWRRPADEVRFLMGFNRDVVK
                                     ***.::*:.***:*:**  *: ********:*. :**********:**:

MSMEG_4490|M.smegmatis_MC2_155      RRRENLNDMGVRMRWVGSRPRMWRSVIKEFDIAEQMTVDNDVITINYCVN
Mvan_3822|M.vanbaalenii_PYR-1       RRRENLNDMGVRMRWVGSRPRMWRSVIKEFDIAEQMTVDNDVITINYCVN
Mflv_2714|M.gilvum_PYR-GCK          RRRENLNDMGVRMRWVGSRPRMWSSVIKEFDIAEQMTVDNDVITINYCVN
TH_0839|M.thermoresistible__bu      RRRENLNDMGVKMRWVGSRPRMWRSVIKEFEIAENMTLDNDVITINYCVN
MMAR_3671|M.marinum_M               RRRDVLNQMGVRIRWVGSRPRLWRSVINELAVAEAMTNNNDVITINYCVN
MUL_3614|M.ulcerans_Agy99           RRRDVLNQMGVRIRWVGSRPRLWRSVINELAVAEAMTNNNDVITINYCVN
Mb2382c|M.bovis_AF2122/97           RRRDTLKKLGVRIRWVGSRPRLWRSVINELAVAEEMTKSNDVITINYCVN
Rv2361c|M.tuberculosis_H37Rv        RRRDTLKKLGVRIRWVGSRPRLWRSVINELAVAEEMTKSNDVITINYCVN
MLBr_00634|M.leprae_Br4923          RRRENLKEMGVRIRWVGSRPRLWRSVINELAIAEHMTAGNDVITINYCVN
MAV_2034|M.avium_104                MRRVNLNTIGVKIRWVGSRPRLWRSVINELAIAEEMTKRNDVITVNYCVN
MAB_1676|M.abscessus_ATCC_1997      RRRHDLNNMGVRFRWAGQKTRLWSSVYKELEITEELTKNNSTLTLTTCIN
                                     **  *: :**::**.*.:.*:* ** :*: ::* :*  *..:*:. *:*

MSMEG_4490|M.smegmatis_MC2_155      YGGRTEIVEAARALAQEAVDGKINPARISEAMFAKHLHRADIPDVDLFIR
Mvan_3822|M.vanbaalenii_PYR-1       YGGRTEIVEAARELAQQAVDGKINPARITEATFAKHLHRADIPDVDLFIR
Mflv_2714|M.gilvum_PYR-GCK          YGGRTEIVEAARELAQQAVDGKIKPNRITEAQFAKHLHRSDIPDVDLFIR
TH_0839|M.thermoresistible__bu      YGGRAEITEAARSIAKEAVAGRINPDRITEKTVARHLHRPDIPDVDLFIR
MMAR_3671|M.marinum_M               YGGRTEIAEATRDIAREVAAGRLNPERITESTIARHMQRPDIPDVDLFLR
MUL_3614|M.ulcerans_Agy99           YGGRTEIAEATRDIAREVAAGRLNPERITESTIARHMQRPDIPDVDLFLR
Mb2382c|M.bovis_AF2122/97           YGGRTEITEATREIAREVAAGRLNPERITESTIARHLQRPDIPDVDLFLR
Rv2361c|M.tuberculosis_H37Rv        YGGRTEITEATREIAREVAAGRLNPERITESTIARHLQRPDIPDVDLFLR
MLBr_00634|M.leprae_Br4923          YGGRTEIAEATREIARLAAAGRLNPERITESTITRHLQRPDIPDVDLFVR
MAV_2034|M.avium_104                YGGRAEIAEATKEIARLAAAGRLNPERITESTVAHHLQRPDIPDVDLFLR
MAB_1676|M.abscessus_ATCC_1997      YGGRAEIAEATRRIARLVESGQLKPDRITEETIAKYLDEPDMPDVDLFLR
                                    ****:**.**:: :*: .  *:::* **:*  .::::...*:******:*

MSMEG_4490|M.smegmatis_MC2_155      TSGEQRASNFLLWQAAYAEYVFQDKLWPDYDRRDLWAACEEYVNRNRRFG
Mvan_3822|M.vanbaalenii_PYR-1       TSGEQRASNFLLWQAAYAEYVFQDKLWPDYDRRDLWAACEEYVNRNRRFG
Mflv_2714|M.gilvum_PYR-GCK          TSGEQRASNFLLWQAAYAEYVFQDKLWPDYDRRDLWAACEEYVHRNRRFG
TH_0839|M.thermoresistible__bu      TSGEQRASNFLLWQSAYAEFVFQDKLWPDYDRRDLWAACEEYVRRNRRFG
MMAR_3671|M.marinum_M               TSGEQRSSNFMLWQSAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFG
MUL_3614|M.ulcerans_Agy99           TSGEQRSSNFMLWQSAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFG
Mb2382c|M.bovis_AF2122/97           TSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRTRRFG
Rv2361c|M.tuberculosis_H37Rv        TSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRTRRFG
MLBr_00634|M.leprae_Br4923          TSGEQRSSNFMLWQAAYTEYIFQDKLWPDYDRRDLWAACEEYASRNRRFG
MAV_2034|M.avium_104                TSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACQEYASRNRRFG
MAB_1676|M.abscessus_ATCC_1997      PSGEFRSSNFMMWQSAYAEFVFQEKMYPDFDRRDLWAACLEYAQRDRRFG
                                    .*** *:***::**:**:*::**:*::**:********* **. * ****

MSMEG_4490|M.smegmatis_MC2_155      RA-
Mvan_3822|M.vanbaalenii_PYR-1       RAE
Mflv_2714|M.gilvum_PYR-GCK          RA-
TH_0839|M.thermoresistible__bu      RA-
MMAR_3671|M.marinum_M               SA-
MUL_3614|M.ulcerans_Agy99           SA-
Mb2382c|M.bovis_AF2122/97           SA-
Rv2361c|M.tuberculosis_H37Rv        SA-
MLBr_00634|M.leprae_Br4923          SA-
MAV_2034|M.avium_104                SA-
MAB_1676|M.abscessus_ATCC_1997      SA-
                                     *