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M. marinum M MMAR_4313 (-)

annotation: chalcone synthase
coordinates: 5304583 - 5305632
length: 349

VAGVAVKFPPNRYQQAEAIGALTEFAGPEFRRFALSSGVEARHTALPLERYAELSGFTEANDAFVDVALD
LGEQALRAALDEAKVRPSEVDVIFSTTVTGLAVPTLEARLAHRVGLREDVKRIPLFGLGCVAGAAGVARM
HDYLRGFPDQVGALLAVELCSLTIQRHDNSVANLVASSLFGDAAAAVVTKGAHRVRGAGAASNGYAGPRV
LATRSRIYPNTENVMGWKIGTSGFQIVLSVDVATVTEKYLGEDVRSFLADHGLTPEDVTTWVCHPGGPRV
IEAVETVLGLPEDALAHTRNSLRNNGNLSSVSILDVLRANLADPPPAGSIGLMIAMGPAFCSELVLLTW
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4313--100% (349)chalcone synthase
M. marinum MMMAR_2470pks10e-10153.67% (354) chalcone synthase, Pks10
M. marinum MMMAR_2474pks11_16e-9951.41% (354) chalcone synthase, Pks11_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1688pks101e-10254.24% (354) chalcone synthase
M. gilvum PYR-GCKMflv_5140-1e-10052.81% (356) chalcone/stilbene synthase domain-containing protein
M. tuberculosis H37RvRv1660pks101e-10254.24% (354) chalcone synthase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. avium 104MAV_1280-1e-15780.52% (349) transferase
M. smegmatis MC2 155MSMEG_0808-2e-9853.95% (354) chalcone synthase Pks10
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1656pks114e-9850.85% (354) chalcone synthase, Pks11
M. vanbaalenii PYR-1Mvan_1196-1e-10053.39% (354) chalcone/stilbene synthase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1688|M.bovis_AF2122/97            ----------MSVIAGVFGALPPYRYSQRELTDSFVSIPDFEGYEDIVRQ
Rv1660|M.tuberculosis_H37Rv         ----------MSVIAGVFGALPPYRYSQRELTDSFVSIPDFEGYEDIVRQ
MUL_1656|M.ulcerans_Agy99           ----------MSVIAGVFGALPPHRYSQSEITESFLEFPGLQEHEEIVRR
Mflv_5140|M.gilvum_PYR-GCK          ---MTDVHTPVSVIAGVQGALPPHRYSQAEVTDAFLAAPAFAEVGDLLRS
Mvan_1196|M.vanbaalenii_PYR-1       ------MNDRISVIAGVQGALPPYRYSQAEITERFVAVPAFAELEDVVRG
MSMEG_0808|M.smegmatis_MC2_155      MENTAFTPSGTCTIAGVHGVLPPHRYTQAEVTEALLDLPGYADFEGIVRS
MMAR_4313|M.marinum_M               -------------MAGVAVKFPPNRYQQAEAIGALTEFAG-----PEFRR
MAV_1280|M.avium_104                -------MGESPSITGVAVKFPPNRYTQSEAIRALTDIAG-----PEFRR
                                                 ::**   :** ** * *    :   .        .* 

Mb1688|M.bovis_AF2122/97            LHASAKVNSRHLVLPLEKYPKLTDFGEANKIFIEKAVDLGVQALAGALDE
Rv1660|M.tuberculosis_H37Rv         LHASAKVNSRHLVLPLEKYPKLTDFGEANKIFIEKAVDLGVQALAGALDE
MUL_1656|M.ulcerans_Agy99           MHAAAKVNSRQFVLPIEQYPALTDFGDTNEIFIEKAVDLGIEALMGALDE
Mflv_5140|M.gilvum_PYR-GCK          LHTNAKVDARHLVLPLEQYPDLLDFGDANDLYIHHAVELGCQALTAALDE
Mvan_1196|M.vanbaalenii_PYR-1       LHKHAKVDARHFVLPMDRYPTLVDFGETNDLYLEHSLDLACEALTAALDE
MSMEG_0808|M.smegmatis_MC2_155      LHKSAKVNSRYLTLPLEEYAALDDFGETNGLFIEHATELGCAALTGALDE
MMAR_4313|M.marinum_M               FALSSGVEARHTALPLERYAELSGFTEANDAFVDVALDLGEQALRAALDE
MAV_1280|M.avium_104                FAHSSGVEFRNTALRLPRYRELSGFSEANDAYLEVALDLGEQALVAALDR
                                    :   : *: *  .* : .*  * .* ::*  ::. : :*.  ** .***.

Mb1688|M.bovis_AF2122/97            SGLRPEDLDVLITATVTGLAVPSLDARIAGRLGLRADVRRVPLFGLGCVA
Rv1660|M.tuberculosis_H37Rv         SGLRPEDLDVLITATVTGLAVPSLDARIAGRLGLRADVRRVPLFGLGCVA
MUL_1656|M.ulcerans_Agy99           AGLTPQDIDLIITTTVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVA
Mflv_5140|M.gilvum_PYR-GCK          AGLAPSDLDVIMSTTVTGIAVPSLDARIAAKLGLRPDVRRVPLFGLGCVA
Mvan_1196|M.vanbaalenii_PYR-1       AGLGPRDLDMIMTTTVTGIAVPSLDARIADRLGLRPDVRRVPLFGLGCVA
MSMEG_0808|M.smegmatis_MC2_155      AGLRPEDVDLIITTTVTGAVVPSLDARIAGRVGLRPDVRRVPIFGLGCVA
MMAR_4313|M.marinum_M               AKVRPSEVDVIFSTTVTGLAVPTLEARLAHRVGLREDVKRIPLFGLGCVA
MAV_1280|M.avium_104                AKVKPSEVDIVFSTTVTGLAVPTLEARLATRVGLRPDVKRVPLFGLGCVA
                                    : : * ::*:::::**** .**:*:**:* ::*** **:*:*:*******

Mb1688|M.bovis_AF2122/97            GAAGVARLHDYLRGAPDGVAALVSVELCSLTYPGYKPTLPGLVGSALFAD
Rv1660|M.tuberculosis_H37Rv         GAAGVARLHDYLRGAPDGVAALVSVELCSLTYPGYKPTLPGLVGSALFAD
MUL_1656|M.ulcerans_Agy99           GAAGVARLHDYLRGAPDGVAVLIAVELCSLTYPAVKPTVSGIVGTALFGD
Mflv_5140|M.gilvum_PYR-GCK          GAAGIARMHDYLRGAPGHVAALISVELCSLTRPALAPTIGSLVGSALFGD
Mvan_1196|M.vanbaalenii_PYR-1       GAAGIARMHDYLRGAPDHIAALVSVELCSLTYPAVEPTMASLVGSALFGD
MSMEG_0808|M.smegmatis_MC2_155      GAAGVARLNDYLRGAPDKVAVLVSVELCSLTH-KHTPSMPTLVAGALFGD
MMAR_4313|M.marinum_M               GAAGVARMHDYLRGFPDQVGALLAVELCSLTIQRHDNSVANLVASSLFGD
MAV_1280|M.avium_104                GAAGVARMHDYLRAFPDQTAALLAVELCSLTIQRHDTSIANLVATSLFGD
                                    ****:**::****. *.  ..*::*******      ::  :*. :**.*

Mb1688|M.bovis_AF2122/97            GAAAVVAAGVKR-----AQDIGADGPDILDSRSHLYPDSLRTMGYDVGSA
Rv1660|M.tuberculosis_H37Rv         GAAAVVAAGVKR-----AQDIGADGPDILDSRSHLYPDSLRTMGYDVGSA
MUL_1656|M.ulcerans_Agy99           GAAAVVAVGDRR-----AEQIRAGGPDILDSRSRLYPESLDIMGWDVGSH
Mflv_5140|M.gilvum_PYR-GCK          GAAAVVAVGEER-----AGHIRASGPDVLDSRSRMYPDSLDIMGWSVNHN
Mvan_1196|M.vanbaalenii_PYR-1       GAAAVIAVGAER-----AETIGATGPEVLDTRSRMYPDSLDTMGWRVGAS
MSMEG_0808|M.smegmatis_MC2_155      GASAVVAVGAGR-----AEQLDPIGPDVLDSRSHLYPDSLHAMGWDIGTK
MMAR_4313|M.marinum_M               AAAAVVTKGAHRVRGAGAASNGYAGPRVLATRSRIYPNTENVMGWKIGTS
MAV_1280|M.avium_104                GAAAVITEGARR---AGAEHT---GPRILATRSRIYPDTEEVMGWKIGGD
                                    .*:**:: *  *     *      ** :* :**::**::   **: :.  

Mb1688|M.bovis_AF2122/97            GFELVLSRDLAAVVEQYLGNDVTTFLASHGLSTTDVGAWVTHPGGPKIIN
Rv1660|M.tuberculosis_H37Rv         GFELVLSRDLAAVVEQYLGNDVTTFLASHGLSTTDVGAWVTHPGGPKIIN
MUL_1656|M.ulcerans_Agy99           GLQLRLAPELTNLIEEYLPDDVDAFLAMHDLTKNDIGAWVSHPGGPKVLD
Mflv_5140|M.gilvum_PYR-GCK          GFQLVLSPELPALIERYLPDDMASFLGEHDLGIGDIATWVSHPGGPKVLE
Mvan_1196|M.vanbaalenii_PYR-1       GFQLILSPNLPELIERYLADDMAGFLGAHDLQIGDIAAWVSHPGGPKVME
MSMEG_0808|M.smegmatis_MC2_155      GFEIVLSAEVPGFVGRYLGDDVTEFLGEHGVATDDVSAWVSHPGGPKVIE
MMAR_4313|M.marinum_M               GFQIVLSVDVATVTEKYLGEDVRSFLADHGLTPEDVTTWVCHPGGPRVIE
MAV_1280|M.avium_104                GFRIVLSADVANIAEKYLGEDVRDFLADHGLAPRDVTTWVCHPGGPRVIE
                                    *:.: *: ::. .  .** :*:  **. *.:   *: :** *****::::

Mb1688|M.bovis_AF2122/97            AITETLDLSPQALELTWRSLGEIGNLSSASVLHVLRDTIAKPPPSGSPGL
Rv1660|M.tuberculosis_H37Rv         AITETLDLSPQALELTWRSLGEIGNLSSASVLHVLRDTIAKPPPSGSPGL
MUL_1656|M.ulcerans_Agy99           AIANSLGLPSDALELTWRSLGEIGNLSSASVLRILRDTIAKVPPSGSPGL
Mflv_5140|M.gilvum_PYR-GCK          AIASALDLPDDALELSWRSLAEIGNLSSSSVLHILRDTIAKKPPAATPGL
Mvan_1196|M.vanbaalenii_PYR-1       AISETLGLPDDALDLAWRSLAEVGNLSSSSVLHVLRDTRAKKPPAGTPGL
MSMEG_0808|M.smegmatis_MC2_155      AIIETLDLPSDALDLTWQSLAEVGNLSSSSVLHVLRDTIRKRPPAGTPGV
MMAR_4313|M.marinum_M               AVETVLGLPEDALAHTRNSLRNNGNLSSVSILDVLRANLADPPPAGSIGL
MAV_1280|M.avium_104                AVESVLDLPADALDHTRNSLRENGNLSSVSVLDVLAANLADPPAPGSIGL
                                    *:   *.*. :**  : .** : ***** *:* :*  .  . *...: *:

Mb1688|M.bovis_AF2122/97            MIAMGPGFCSELVLLRWH
Rv1660|M.tuberculosis_H37Rv         MIAMGPGFCSELVLLRWH
MUL_1656|M.ulcerans_Agy99           MLAMGPGFCAELVLLRWH
Mflv_5140|M.gilvum_PYR-GCK          LMAMGPGFCSELVLLRWH
Mvan_1196|M.vanbaalenii_PYR-1       LMAMGPGFCSELVLLRWR
MSMEG_0808|M.smegmatis_MC2_155      LMAMGPGFCSELVLLRWR
MMAR_4313|M.marinum_M               MIAMGPAFCSELVLLTW-
MAV_1280|M.avium_104                MIAMGPAFCSELVLLAF-
                                    ::****.**:***** :