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VAGVAVKFPPNRYQQAEAIGALTEFAGPEFRRFALSSGVEARHTALPLERYAELSGFTEANDAFVDVALD LGEQALRAALDEAKVRPSEVDVIFSTTVTGLAVPTLEARLAHRVGLREDVKRIPLFGLGCVAGAAGVARM HDYLRGFPDQVGALLAVELCSLTIQRHDNSVANLVASSLFGDAAAAVVTKGAHRVRGAGAASNGYAGPRV LATRSRIYPNTENVMGWKIGTSGFQIVLSVDVATVTEKYLGEDVRSFLADHGLTPEDVTTWVCHPGGPRV IEAVETVLGLPEDALAHTRNSLRNNGNLSSVSILDVLRANLADPPPAGSIGLMIAMGPAFCSELVLLTW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4313 | - | - | 100% (349) | chalcone synthase |
M. marinum M | MMAR_2470 | pks10 | e-101 | 53.67% (354) | chalcone synthase, Pks10 |
M. marinum M | MMAR_2474 | pks11_1 | 6e-99 | 51.41% (354) | chalcone synthase, Pks11_1 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1688 | pks10 | 1e-102 | 54.24% (354) | chalcone synthase |
M. gilvum PYR-GCK | Mflv_5140 | - | 1e-100 | 52.81% (356) | chalcone/stilbene synthase domain-containing protein |
M. tuberculosis H37Rv | Rv1660 | pks10 | 1e-102 | 54.24% (354) | chalcone synthase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. avium 104 | MAV_1280 | - | 1e-157 | 80.52% (349) | transferase |
M. smegmatis MC2 155 | MSMEG_0808 | - | 2e-98 | 53.95% (354) | chalcone synthase Pks10 |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_1656 | pks11 | 4e-98 | 50.85% (354) | chalcone synthase, Pks11 |
M. vanbaalenii PYR-1 | Mvan_1196 | - | 1e-100 | 53.39% (354) | chalcone/stilbene synthase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1688|M.bovis_AF2122/97 ----------MSVIAGVFGALPPYRYSQRELTDSFVSIPDFEGYEDIVRQ Rv1660|M.tuberculosis_H37Rv ----------MSVIAGVFGALPPYRYSQRELTDSFVSIPDFEGYEDIVRQ MUL_1656|M.ulcerans_Agy99 ----------MSVIAGVFGALPPHRYSQSEITESFLEFPGLQEHEEIVRR Mflv_5140|M.gilvum_PYR-GCK ---MTDVHTPVSVIAGVQGALPPHRYSQAEVTDAFLAAPAFAEVGDLLRS Mvan_1196|M.vanbaalenii_PYR-1 ------MNDRISVIAGVQGALPPYRYSQAEITERFVAVPAFAELEDVVRG MSMEG_0808|M.smegmatis_MC2_155 MENTAFTPSGTCTIAGVHGVLPPHRYTQAEVTEALLDLPGYADFEGIVRS MMAR_4313|M.marinum_M -------------MAGVAVKFPPNRYQQAEAIGALTEFAG-----PEFRR MAV_1280|M.avium_104 -------MGESPSITGVAVKFPPNRYTQSEAIRALTDIAG-----PEFRR ::** :** ** * * : . .* Mb1688|M.bovis_AF2122/97 LHASAKVNSRHLVLPLEKYPKLTDFGEANKIFIEKAVDLGVQALAGALDE Rv1660|M.tuberculosis_H37Rv LHASAKVNSRHLVLPLEKYPKLTDFGEANKIFIEKAVDLGVQALAGALDE MUL_1656|M.ulcerans_Agy99 MHAAAKVNSRQFVLPIEQYPALTDFGDTNEIFIEKAVDLGIEALMGALDE Mflv_5140|M.gilvum_PYR-GCK LHTNAKVDARHLVLPLEQYPDLLDFGDANDLYIHHAVELGCQALTAALDE Mvan_1196|M.vanbaalenii_PYR-1 LHKHAKVDARHFVLPMDRYPTLVDFGETNDLYLEHSLDLACEALTAALDE MSMEG_0808|M.smegmatis_MC2_155 LHKSAKVNSRYLTLPLEEYAALDDFGETNGLFIEHATELGCAALTGALDE MMAR_4313|M.marinum_M FALSSGVEARHTALPLERYAELSGFTEANDAFVDVALDLGEQALRAALDE MAV_1280|M.avium_104 FAHSSGVEFRNTALRLPRYRELSGFSEANDAYLEVALDLGEQALVAALDR : : *: * .* : .* * .* ::* ::. : :*. ** .***. Mb1688|M.bovis_AF2122/97 SGLRPEDLDVLITATVTGLAVPSLDARIAGRLGLRADVRRVPLFGLGCVA Rv1660|M.tuberculosis_H37Rv SGLRPEDLDVLITATVTGLAVPSLDARIAGRLGLRADVRRVPLFGLGCVA MUL_1656|M.ulcerans_Agy99 AGLTPQDIDLIITTTVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVA Mflv_5140|M.gilvum_PYR-GCK AGLAPSDLDVIMSTTVTGIAVPSLDARIAAKLGLRPDVRRVPLFGLGCVA Mvan_1196|M.vanbaalenii_PYR-1 AGLGPRDLDMIMTTTVTGIAVPSLDARIADRLGLRPDVRRVPLFGLGCVA MSMEG_0808|M.smegmatis_MC2_155 AGLRPEDVDLIITTTVTGAVVPSLDARIAGRVGLRPDVRRVPIFGLGCVA MMAR_4313|M.marinum_M AKVRPSEVDVIFSTTVTGLAVPTLEARLAHRVGLREDVKRIPLFGLGCVA MAV_1280|M.avium_104 AKVKPSEVDIVFSTTVTGLAVPTLEARLATRVGLRPDVKRVPLFGLGCVA : : * ::*:::::**** .**:*:**:* ::*** **:*:*:******* Mb1688|M.bovis_AF2122/97 GAAGVARLHDYLRGAPDGVAALVSVELCSLTYPGYKPTLPGLVGSALFAD Rv1660|M.tuberculosis_H37Rv GAAGVARLHDYLRGAPDGVAALVSVELCSLTYPGYKPTLPGLVGSALFAD MUL_1656|M.ulcerans_Agy99 GAAGVARLHDYLRGAPDGVAVLIAVELCSLTYPAVKPTVSGIVGTALFGD Mflv_5140|M.gilvum_PYR-GCK GAAGIARMHDYLRGAPGHVAALISVELCSLTRPALAPTIGSLVGSALFGD Mvan_1196|M.vanbaalenii_PYR-1 GAAGIARMHDYLRGAPDHIAALVSVELCSLTYPAVEPTMASLVGSALFGD MSMEG_0808|M.smegmatis_MC2_155 GAAGVARLNDYLRGAPDKVAVLVSVELCSLTH-KHTPSMPTLVAGALFGD MMAR_4313|M.marinum_M GAAGVARMHDYLRGFPDQVGALLAVELCSLTIQRHDNSVANLVASSLFGD MAV_1280|M.avium_104 GAAGVARMHDYLRAFPDQTAALLAVELCSLTIQRHDTSIANLVATSLFGD ****:**::****. *. ..*::******* :: :*. :**.* Mb1688|M.bovis_AF2122/97 GAAAVVAAGVKR-----AQDIGADGPDILDSRSHLYPDSLRTMGYDVGSA Rv1660|M.tuberculosis_H37Rv GAAAVVAAGVKR-----AQDIGADGPDILDSRSHLYPDSLRTMGYDVGSA MUL_1656|M.ulcerans_Agy99 GAAAVVAVGDRR-----AEQIRAGGPDILDSRSRLYPESLDIMGWDVGSH Mflv_5140|M.gilvum_PYR-GCK GAAAVVAVGEER-----AGHIRASGPDVLDSRSRMYPDSLDIMGWSVNHN Mvan_1196|M.vanbaalenii_PYR-1 GAAAVIAVGAER-----AETIGATGPEVLDTRSRMYPDSLDTMGWRVGAS MSMEG_0808|M.smegmatis_MC2_155 GASAVVAVGAGR-----AEQLDPIGPDVLDSRSHLYPDSLHAMGWDIGTK MMAR_4313|M.marinum_M AAAAVVTKGAHRVRGAGAASNGYAGPRVLATRSRIYPNTENVMGWKIGTS MAV_1280|M.avium_104 GAAAVITEGARR---AGAEHT---GPRILATRSRIYPDTEEVMGWKIGGD .*:**:: * * * ** :* :**::**:: **: :. Mb1688|M.bovis_AF2122/97 GFELVLSRDLAAVVEQYLGNDVTTFLASHGLSTTDVGAWVTHPGGPKIIN Rv1660|M.tuberculosis_H37Rv GFELVLSRDLAAVVEQYLGNDVTTFLASHGLSTTDVGAWVTHPGGPKIIN MUL_1656|M.ulcerans_Agy99 GLQLRLAPELTNLIEEYLPDDVDAFLAMHDLTKNDIGAWVSHPGGPKVLD Mflv_5140|M.gilvum_PYR-GCK GFQLVLSPELPALIERYLPDDMASFLGEHDLGIGDIATWVSHPGGPKVLE Mvan_1196|M.vanbaalenii_PYR-1 GFQLILSPNLPELIERYLADDMAGFLGAHDLQIGDIAAWVSHPGGPKVME MSMEG_0808|M.smegmatis_MC2_155 GFEIVLSAEVPGFVGRYLGDDVTEFLGEHGVATDDVSAWVSHPGGPKVIE MMAR_4313|M.marinum_M GFQIVLSVDVATVTEKYLGEDVRSFLADHGLTPEDVTTWVCHPGGPRVIE MAV_1280|M.avium_104 GFRIVLSADVANIAEKYLGEDVRDFLADHGLAPRDVTTWVCHPGGPRVIE *:.: *: ::. . .** :*: **. *.: *: :** *****:::: Mb1688|M.bovis_AF2122/97 AITETLDLSPQALELTWRSLGEIGNLSSASVLHVLRDTIAKPPPSGSPGL Rv1660|M.tuberculosis_H37Rv AITETLDLSPQALELTWRSLGEIGNLSSASVLHVLRDTIAKPPPSGSPGL MUL_1656|M.ulcerans_Agy99 AIANSLGLPSDALELTWRSLGEIGNLSSASVLRILRDTIAKVPPSGSPGL Mflv_5140|M.gilvum_PYR-GCK AIASALDLPDDALELSWRSLAEIGNLSSSSVLHILRDTIAKKPPAATPGL Mvan_1196|M.vanbaalenii_PYR-1 AISETLGLPDDALDLAWRSLAEVGNLSSSSVLHVLRDTRAKKPPAGTPGL MSMEG_0808|M.smegmatis_MC2_155 AIIETLDLPSDALDLTWQSLAEVGNLSSSSVLHVLRDTIRKRPPAGTPGV MMAR_4313|M.marinum_M AVETVLGLPEDALAHTRNSLRNNGNLSSVSILDVLRANLADPPPAGSIGL MAV_1280|M.avium_104 AVESVLDLPADALDHTRNSLRENGNLSSVSVLDVLAANLADPPAPGSIGL *: *.*. :** : .** : ***** *:* :* . . *...: *: Mb1688|M.bovis_AF2122/97 MIAMGPGFCSELVLLRWH Rv1660|M.tuberculosis_H37Rv MIAMGPGFCSELVLLRWH MUL_1656|M.ulcerans_Agy99 MLAMGPGFCAELVLLRWH Mflv_5140|M.gilvum_PYR-GCK LMAMGPGFCSELVLLRWH Mvan_1196|M.vanbaalenii_PYR-1 LMAMGPGFCSELVLLRWR MSMEG_0808|M.smegmatis_MC2_155 LMAMGPGFCSELVLLRWR MMAR_4313|M.marinum_M MIAMGPAFCSELVLLTW- MAV_1280|M.avium_104 MIAMGPAFCSELVLLAF- ::****.**:***** :