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MSFVIANPEMLAAAATDLAGIRSAISAATAAAAAPTIQVAAAGADEVSLAISALFGQHAQAYQALSAQAT IFHDQFVQALTSGGNLYAAAESHTVEQMVLNAINAPTQTLFGRPLIGDGANGTAENPDGQNGGLLFGNGG NGFTQTTAGVAGGNGGSAGLIGNGGAGGIGGAGTGTGGHGGAGGAGGRAWLWGTGGAGGAGAAAIGNAVT PGGAGGAGGAGGDGGWLFGDGGAGGTGGNGGSGFNSLTSSVGGAGGAGGHAGLFGAGGTGGTGGIGGQNT ETGPAASNGGAGGAGGGGGYLVGDGGAGGTGGAGGKNSSGGATLTGGTGGTGGAGGAAGWLYGSGGAGGA GGLNNAGGATGGTGGTGGAGGSGAWLYGNGGAAGAGGNGGNNTSAGTGGVGASGGTGGNAGLIGAGGHGG AGGAGGNQTGGVGNGGAGGNGGAGGAGGQLYGNGGDGGNGGAGGANIAGGNGSDGGAAGHGGAGGSARLI GAGGHGGDGGAGGNTAGRRADAIAGTGGDGGNGGNGGLLSGNAGAGGHGGAGGSSTATTTTGTPPTGATG GNGGNGGAGGTAGFTGSGGIGGNGGAGGTGGNAGVALSVGSTGGLGGNGGSGGLGGGGGSLFGNGGAGGV GATGGNAGSGIGPASVGGNGGKGGVGAAGGLAGQIGNGGSGGSGGAGGNGGTGDTAGNGGNGGAGAVGGN AQLIGNGGNGGGGGNGGTGATPGTGGAGAAGGTGGTLFGAPGTTGADGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3420 | PE_PGRS52 | - | 100% (749) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 0.0 | 54.09% (867) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 0.0 | 49.71% (869) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-148 | 47.66% (663) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3388 | PE_PGRS52 | 0.0 | 93.45% (748) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 4e-12 | 36.67% (90) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-51 | 38.66% (388) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1208 | - | 0.0 | 50.00% (898) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 3e-23 | 40.59% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-135 | 42.03% (778) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 40.92% (303) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 46.25% (921) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-145 | 45.21% (710) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3420|M.bovis_AF2122/97 --------------------------------------------------
Rv3388|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 ----------MSFVIANPEMLAAAATDLAGIRSAISAATAAAAAPTIQVA
Rv3388|M.tuberculosis_H37Rv ----------MSFVIANPEMLAAAATDLAGIRSAISAATAAAAAPTIQVA
MMAR_1208|M.marinum_M ----------MAFVLVAPEMVTAAASDLANIGSAINTANTAVAAPTAELL
MUL_4367|M.ulcerans_Agy99 ----------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVL
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAAT
Mb3420|M.bovis_AF2122/97 AAGADEVSLAISALFGQHAQAYQALSAQATIFHDQFVQALTSGGNLYAAA
Rv3388|M.tuberculosis_H37Rv AAGADEVSLAISALFGQHAQAYQALSAQATIFHDQFVQALTSGGNLYAAA
MMAR_1208|M.marinum_M AAGTDEVSEAIASLFSGHALDYQSLGARMTAFHDQFVAALTAGGGLYSSA
MUL_4367|M.ulcerans_Agy99 PAAGDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRI
Mb3420|M.bovis_AF2122/97 ES--------------------------------------HTVEQMVLNA
Rv3388|M.tuberculosis_H37Rv ES--------------------------------------HTVEQMVLNA
MMAR_1208|M.marinum_M EAA------------------------------------AATPLQDLLNV
MUL_4367|M.ulcerans_Agy99 EALN--------------------------------MWPLQELEQQALGV
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PS---------------------------------------ILSPSLLSP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DN--------------------------------------VMLVSAFLAA
Mb3420|M.bovis_AF2122/97 IN--------------------APTQTLFG--------RPLIGDGANGTA
Rv3388|M.tuberculosis_H37Rv IN--------------------APTQTLFG--------RPLIGDGANGTA
MMAR_1208|M.marinum_M VN--------------------APTQALLG--------RPLIGDGADGTA
MUL_4367|M.ulcerans_Agy99 VN--------------------APSMALFG--------RPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD------------------------------------NDFLSHNDTDFA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AA---------------------------------------LAQNVGGAM
Mb3420|M.bovis_AF2122/97 E-NPDGQNGGLLFGNGGNGFTQTTAGVAGGNGGSAGLIG-NGGAGGIGGA
Rv3388|M.tuberculosis_H37Rv E-NPDGQNGGLLFGNGGNGFTQTTAGVAGGNGGSAGLIG-NGGAGGGGGA
MMAR_1208|M.marinum_M P-GQAGGAGGLLYGNGGNGAAGTNPGVAGGAGGAAGLIG-NGGAGGIGGA
MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGGLG-AAGANGGAGGSAGLIG-TGGVGGAGGV
Mflv_5091|M.gilvum_PYR-GCK Q-N-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG
Mvan_1264|M.vanbaalenii_PYR-1 Q-N-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG
MSMEG_0868|M.smegmatis_MC2_155 D-NPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA
TH_3810|M.thermoresistible__bu -----------VDGDGG----------SGGRTGLFSKLS-RGGDGGDGGL
MAB_4284c|M.abscessus_ATCC_199 S------HNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 G-----YERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG
Mb3420|M.bovis_AF2122/97 GTG--TGGHGGAGGAGGRAWLWGTGGAGGAGAAAIG-----N-----AVT
Rv3388|M.tuberculosis_H37Rv G------AAGGLGGNGG--WLYGNGGAGGIGGAGTG-----TGGHGGAGG
MMAR_1208|M.marinum_M G------GSGGAGGTGG--WLYGNGGAGGAGGAGAPGLVSFNGSNGGNGG
MUL_4367|M.ulcerans_Agy99 GAAGMTGGSGGAGGGGG--WLWGAGGSGGAAGAGGS-----GGSGGWLWG
Mflv_5091|M.gilvum_PYR-GCK G------GNGGNGGNAGAFALFGNGGNGGNGGVGVVG----ATGAVG--A
Mvan_1264|M.vanbaalenii_PYR-1 S------GDGGNGGDAGLFSLFGRGGNGGNGGVGIAG----ATGAVG--A
MSMEG_0868|M.smegmatis_MC2_155 G------LDGGNGGSGG--LLMGIGGAGGAGGVGADG----TSAHVDGGT
TH_3810|M.thermoresistible__bu G------GNGGHGGGTGIISLLSLAGNGGNGGNGYRT-------------
MAB_4284c|M.abscessus_ATCC_199 G-----DGAVAVGGSNSGPIASGQGSTAVNGDVRDSN-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPE
Mb3420|M.bovis_AF2122/97 PG------GAGGAGGAGGDG------------------------------
Rv3388|M.tuberculosis_H37Rv AGGRAWLWGTGGAGGAGGDG------------------------------
MMAR_1208|M.marinum_M NGGAAGWWGTGGAGGAGGEGGAAGGDPAGIAYGSTGGVGGNGGSGGNG--
MUL_4367|M.ulcerans_Agy99 NAGQTAGAGVGGAGGAGGAGDAGDQGVSGVAPGEAGAVGFAGGAGGAGGA
Mflv_5091|M.gilvum_PYR-GCK PGVAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG----
Mvan_1264|M.vanbaalenii_PYR-1 PGVAGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG----
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGF
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TALARGAALAAANAPLFASS------------------------------
Mb3420|M.bovis_AF2122/97 -----------GWLFGDGGAGGTGGNGGSGFNSLT----SSVGGAG----
Rv3388|M.tuberculosis_H37Rv -----------GWLFGDGGAGGTGGNGGSGFNSLT----SSVGGAG----
MMAR_1208|M.marinum_M -----------GWFAGNAGAGGNGGVGGDGNAADS----GLVGGAGG---
MUL_4367|M.ulcerans_Agy99 G-----GNGVGGGVNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDGG---
Mflv_5091|M.gilvum_PYR-GCK ----------AVGSAGAAGEAGETGTWG--NAGLPG-KAGDAGGAG----
Mvan_1264|M.vanbaalenii_PYR-1 ----------AVGSAGTAGSAGAPGVWG--NAGLPG-AAGAAGGAG----
MSMEG_0868|M.smegmatis_MC2_155 GYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPG-KGGGGGGGGGGAI
TH_3810|M.thermoresistible__bu -------------TDNNALDGGHGGNGGN---------------------
MAB_4284c|M.abscessus_ATCC_199 --------------IINADHGSNVGVDQSQTRVGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------TAALAYAQDPGTGAVDQYSLPDYLY--------------
Mb3420|M.bovis_AF2122/97 --------------GAGGHAG-------LFGAGGTGGTGG----------
Rv3388|M.tuberculosis_H37Rv --------------GAGGHAG-------LFGAGGTGGTGG----------
MMAR_1208|M.marinum_M ------------VGGAGGAAG-------LFGDGGAGGQGGDGAVS-DALA
MUL_4367|M.ulcerans_Agy99 ------------TGGAGGAAG-------VGGAAGTGGTGGAAGVAGTGGD
Mflv_5091|M.gilvum_PYR-GCK ------------AVGAAGAAG------TVGTAGATGGTG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ------------AIGTAGVAG------AAGTAGATGGTG-----------
MSMEG_0868|M.smegmatis_MC2_155 LIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEG-TGST
TH_3810|M.thermoresistible__bu -------------VGFFSLFN-------LGGAGGWGGSG-----------
MAB_4284c|M.abscessus_ATCC_199 --------------DYTNVSG--------HGSADIDKSVT----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------VPVDPEPG--------DDELAYSAVGE----------
Mb3420|M.bovis_AF2122/97 -----IGGQNTE--TGPAASNGGAG--------------GAGGGG-----
Rv3388|M.tuberculosis_H37Rv -----IGGQNTE--TGPAASNGGAG--------------GAGGGG-----
MMAR_1208|M.marinum_M ASHGGTGGDGGR--SGWLSGNAGAG--------------GAGGAGGSTNG
MUL_4367|M.ulcerans_Agy99 GGDGGAGGAGSD--ASLAGQAGFAG--------------GSGGAGG----
Mflv_5091|M.gilvum_PYR-GCK -----TGANGGAGGVGGVGGTGAAG--------------AAGGAGGL-GE
Mvan_1264|M.vanbaalenii_PYR-1 -----VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTA-GE
MSMEG_0868|M.smegmatis_MC2_155 AEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGD-GI
TH_3810|M.thermoresistible__bu -----------------VDGVDVVG-------------------------
MAB_4284c|M.abscessus_ATCC_199 -----VVDDHSQRNTTNINDSFNTDR------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------EDAESPTVVIEKLFLPE--------------DSEPRRRPVLL
Mb3420|M.bovis_AF2122/97 -GYLVGDGGAGGT--GGAG---GKNSSGGATLTG-------GTGGTGGAG
Rv3388|M.tuberculosis_H37Rv -GYLVGDGGAGGT--GGAG---GKNSSGGATLTG-------GTGGTGGAG
MMAR_1208|M.marinum_M IGNFAGNGGAGGN--GGAAGLFGNGAAGGAGGAGGASQTFTGAGGAGGTG
MUL_4367|M.ulcerans_Agy99 VGGSAGAGGVNGS--GGDG---GAGAAGGAGGASATVAGSGGVGGDGGAG
Mflv_5091|M.gilvum_PYR-GCK TGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTG-------AVGGVGGKG
Mvan_1264|M.vanbaalenii_PYR-1 TGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATG-------GAGGVGGKG
MSMEG_0868|M.smegmatis_MC2_155 DGGTGGAGGMGEIYSGADGEATGISAGGDGGSAT-------GADSLGGRG
TH_3810|M.thermoresistible__bu -GNPDG----------------GTPGAHGESHTP-------GVYTD----
MAB_4284c|M.abscessus_ATCC_199 -STNIGSGNTTNTEIGSHN----QANIGTSTSAG-------GSAAVGGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VGSGLAVVGISAVLALEIALAIGIRTTGTVALQP-------TPNQHLIVP
Mb3420|M.bovis_AF2122/97 G----AAG---------------WLYGSGGAGGAG---GLNNAG------
Rv3388|M.tuberculosis_H37Rv G----AAG---------------WLYGSGGAGGAGGAGGLNNAG------
MMAR_1208|M.marinum_M G----AGG---------------WLYGNGGAGGAG---GVGGAG------
MUL_4367|M.ulcerans_Agy99 G----AAGGG---------VGAASLGGDGGHAGAGGAGGEGLSGGFN---
Mflv_5091|M.gilvum_PYR-GCK ----IQGGQG-------------LQGGKGGDGGAGGKGGDADSMGS----
Mvan_1264|M.vanbaalenii_PYR-1 ----IQGGQG-------------LQGGQGGDGGTGGTGGDATSMGE----
MSMEG_0868|M.smegmatis_MC2_155 GTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATG
TH_3810|M.thermoresistible__bu ------------------------RQGEDGEDGTG---------------
MAB_4284c|M.abscessus_ATCC_199 G-----------------------LAGNAGLAGNAG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------TEQAPAPPPVQAS--------------
Mb3420|M.bovis_AF2122/97 ---------------GATGGTGGTGGAGGSG-------------------
Rv3388|M.tuberculosis_H37Rv ---------------GATGGTGGTGGAGGSG-------------------
MMAR_1208|M.marinum_M ---------------IGTGGLGSNGGNGGTGG------------------
MUL_4367|M.ulcerans_Agy99 --------------TGAAGGIGGAGGAGGTGGDSG--------------G
Mflv_5091|M.gilvum_PYR-GCK --------------AGATGGKGGNGGNGGRGGLFG---------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------AGATGGKGGNGGNGGRGSLFG---------------
MSMEG_0868|M.smegmatis_MC2_155 VATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAA
TH_3810|M.thermoresistible__bu ---------------TGIGGRGGNGGSSSGT-------------------
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGNAG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------APQPKISVPEPVAAPKP------------------
Mb3420|M.bovis_AF2122/97 -AWLYGNGGA----------------------AGAGG---NGGNNTSAG-
Rv3388|M.tuberculosis_H37Rv -AWLYGNGGA----------------------AGAGG---NGGNNTSAG-
MMAR_1208|M.marinum_M IGGLIGNGGA----------------------GGAGG---AGSASGPSGY
MUL_4367|M.ulcerans_Agy99 VGGVNGDGGA----------------------GGGGGRGGDGGSSTSTSG
Mflv_5091|M.gilvum_PYR-GCK KGGNAGNGAD----------------------GGTGG---AGGAGGTGG-
Mvan_1264|M.vanbaalenii_PYR-1 RGGNAGNGGN----------------------GGTGG---NGGNGGTGG-
MSMEG_0868|M.smegmatis_MC2_155 QGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGG---DGGFNGTGGA
TH_3810|M.thermoresistible__bu -HPMAEDGEH------------------------------VKALDGRPGL
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGN----------------------AGLAG---NAGLAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LSPPVAAPLP------------------------------AAPPPAAPPL
Mb3420|M.bovis_AF2122/97 TGGVGASGG-----------------TGGNAGL-IGAGGHG---GAGGAG
Rv3388|M.tuberculosis_H37Rv TGGVGASGG-----------------TGGNAGL-IGAGGHG---GAGGAG
MMAR_1208|M.marinum_M SGGNGGNGG-----------------NGGAAQL-IGAGGGGGVAGVGGAG
MUL_4367|M.ulcerans_Agy99 VGGAGGAGG-----------------NGGNAGFGVSAGGTGGSAGDGGAG
Mflv_5091|M.gilvum_PYR-GCK TGGAGGTGG-----------------TGGTGGI-GGAGSTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 TGGNGGTGG-----------------TGGTGGI-GGAGSTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 TGGRGGDGAGASVWKANGQHSTGQTDTGGNGGR-GGDGGTFVNAGANGNG
TH_3810|M.thermoresistible__bu DGGNGSHGG-----------------NGGHGGR-----------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGN------------------AGLAGN-AGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PEAPPIPAAP----------------PVVPVPVVVPPVPVPVPVRIPVPD
Mb3420|M.bovis_AF2122/97 GN------------QTGGVGNGGAG-------------------------
Rv3388|M.tuberculosis_H37Rv GN------------QTGGVGNGGAG-------------------------
MMAR_1208|M.marinum_M GTGA-------AAGVTGSAGASGVGGRLY--------SGNGIPDIFGRPL
MUL_4367|M.ulcerans_Agy99 GGAGGVDGVGGASGNGGAAGAGGAGGSGIGAGIDGGAGGAGGTGGAAGFP
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTG-GTGGTGGTGGTGGKGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG-GTGGTGGTGGTGGKGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155 GAGGAGGVSEGEGGTGGHGGDGGRGGDG----------------------
TH_3810|M.thermoresistible__bu ---------------GGFLG------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAG-------LAGNAGLAGNAGLAG------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVSPPQLLAPPRLSVPQPVQPPVRVP------------------------
Mb3420|M.bovis_AF2122/97 ---------GNGGAGGAG---------------------GQLYGNGGDGG
Rv3388|M.tuberculosis_H37Rv ---------GNGGAGGAG---------------------GQLYGNGGDGG
MMAR_1208|M.marinum_M IGDGADGAPGTGQAGGDG---------------------GWLYGNGGNGG
MUL_4367|M.ulcerans_Agy99 GGGGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK ---------GTGGAGGTG-------------------GDGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ---------GTGGDGGTG-------------------GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 ---------ALGGNGGTGGVGL---------------GNGGKGGNGGNGG
TH_3810|M.thermoresistible__bu ----------IGGSGGWG-------------------------GHGGNGG
MAB_4284c|M.abscessus_ATCC_199 ---------NAGLAGNAG-----------------------LAGNAGLAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------QPPSPPQVG-------------------------GTVPQSP
Mb3420|M.bovis_AF2122/97 ------------------NGGAG----------GANIAGGNGSDG-----
Rv3388|M.tuberculosis_H37Rv ------------------NGGAG----------GANIAGGNGSDG-----
MMAR_1208|M.marinum_M SGAAGQAGGAGGAAGLIGNGGAGGTG-------GSGAAGGNGGAGGWLFG
MUL_4367|M.ulcerans_Agy99 AGGSAAFNGVNGAGGAGGNGGAGGGGGAGASGIGAGVAGGDGGTGG----
Mflv_5091|M.gilvum_PYR-GCK TG---------GTGGTGGTGGAG------------DGTGGTGGTGG----
Mvan_1264|M.vanbaalenii_PYR-1 TG---------GTGGTGGTGGAG------------DGLGGTGGTGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTA-TGTATGGNGGNGGN---
TH_3810|M.thermoresistible__bu D---------------------------------TDADGGNGGDGG----
MAB_4284c|M.abscessus_ATCC_199 N----------------------------------AAVAGNAAVAG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PQ--------------------------------HQTPPGEGTPPK----
Mb3420|M.bovis_AF2122/97 --------------------GAAGHGGAGG-----------------SAR
Rv3388|M.tuberculosis_H37Rv --------------------GAAGHGGAGG-----------------SAR
MMAR_1208|M.marinum_M NGGNGGTGGDAVAGLPGLNGGNGGNGGAGG-----------------AAG
MUL_4367|M.ulcerans_Agy99 ------------TGGAAGTGGAAGTGGTGG-----------------AAG
Mflv_5091|M.gilvum_PYR-GCK ------------------TGGQGGQGGQGG-----------------TGG
Mvan_1264|M.vanbaalenii_PYR-1 ------------------TGGFGGQGGQGG-----------------TGG
MSMEG_0868|M.smegmatis_MC2_155 ---------------GDADGHRGGKGGDGGEALIRATVIGSNASGTATGG
TH_3810|M.thermoresistible__bu ---------------------NGGSAGRGG-----------------TGG
MAB_4284c|M.abscessus_ATCC_199 ------------------NAAVAGNAAVGG------------------VL
MLBr_01183|M.leprae_Br4923 -----------------------------------------------MPL
MAV_4827|M.avium_104 ---------------------PDGPGNYGG-------------------G
Mb3420|M.bovis_AF2122/97 LIGAGG-HGGDGGAGG-----------------------NTAGRRADAIA
Rv3388|M.tuberculosis_H37Rv LIGAGG-HGGDGGAGG-----------------------NTAGRRADAIA
MMAR_1208|M.marinum_M WWGHGG-IGGQGGTGGA-----------------AGGFANTAPSTNGLLG
MUL_4367|M.ulcerans_Agy99 AAGSAG-DGGAGGAGGAGD-------------DGSAGVVSGDPGTAGKAG
Mflv_5091|M.gilvum_PYR-GCK TGGQGG-LGGGGGTG-----------------------GQGGTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 TGGQGG-LGGVGGTG-----------------------GTGGTGGTGGQG
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHG
TH_3810|M.thermoresistible__bu LRGVFGINGGNGRAG------------------------------LGGRG
MAB_4284c|M.abscessus_ATCC_199 NTGVSGAIGGSSHVGG------------------------AINESLGGSG
MLBr_01183|M.leprae_Br4923 FLNAEP------------------------------------QALTAAAN
MAV_4827|M.avium_104 HVPTPG-AGGSGGSGG-------------------------GHVPTPGAG
Mb3420|M.bovis_AF2122/97 GTGGDGGNGGN----------GGLLSGNAGAGGHGGAGGSSTATTTTG-T
Rv3388|M.tuberculosis_H37Rv GTGGDGGNGGN----------GGLLSGNAGAGGHGGAGGSSTATTTTG-T
MMAR_1208|M.marinum_M GNGGNGGDGGA----------GGWLFGDAGAGGQGGTGGAANDPLVGGST
MUL_4367|M.ulcerans_Agy99 GAGGAGGVGGNG--------VAGGVNGSGGAGGAGGAGGTGGAGASGVPA
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQG
MSMEG_0868|M.smegmatis_MC2_155 GNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAA
TH_3810|M.thermoresistible__bu XXXXGGGVG------------AAVRSGNGVFSGGGGTPSAGFGVPTTIQF
MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVG------------GGAHTGVGGGVSTGVGVGSHVGGGISESL
MLBr_01183|M.leprae_Br4923 TLEGLSAAT-----------VASNAAAAQLTTEIAPPAADDVSILLAHFF
MAV_4827|M.avium_104 GSGGSGGGHVP-------------TPGTGGPGGTGGSGGGHVPTPGAGTP
. . .
Mb3420|M.bovis_AF2122/97 PPTGATGGNG--------GNGGAGGTAG----FTGSG-GIGGNGGAGGTG
Rv3388|M.tuberculosis_H37Rv PPTGATGGNG--------GNGGAGGTAG----FTGSG-GIGGNGGAGGTG
MMAR_1208|M.marinum_M GGSGGAGGNGGTAG--LFGAGGAGGTGG----TAGAGIAVGSNGGHGGQG
MUL_4367|M.ulcerans_Agy99 SVDGGDGGAGGAGG--AAGTGGSGGSAG----NTGAG-GAGGAGGAGGSA
Mflv_5091|M.gilvum_PYR-GCK GPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASG
Mvan_1264|M.vanbaalenii_PYR-1 GPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASG
MSMEG_0868|M.smegmatis_MC2_155 NPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATA
TH_3810|M.thermoresistible__bu PAGSCTSRAVSREG---IMPSSRAASAR-----------AGAACASSTSR
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGG------GAHTGVGG----GVSTGVGVGSHVGGGISE
MLBr_01183|M.leprae_Br4923 SGHGRQYQAHASQG----ATNHQDLIQS----------LLTSSSAYAGTE
MAV_4827|M.avium_104 GGSGGGHLPFPGAG------STPGGSGG------GHLPTPGAGTPGGGLG
.
Mb3420|M.bovis_AF2122/97 GNAGVAL--SVGSTGG-----LGGNGGSG----GLGGGGGS-----LFGN
Rv3388|M.tuberculosis_H37Rv GNAGVAL--SVGSTGG-----LGGNGGSG----GLGGGGGS-----LFGN
MMAR_1208|M.marinum_M GYGGWLG--GSGGAGG-----TGGTGGSGDIYAGAGGTGGSGGAARLFGT
MUL_4367|M.ulcerans_Agy99 ASTGVNGDGGAGGAGG-----VGGLGGDSAATAGGGGAGGDG------GK
Mflv_5091|M.gilvum_PYR-GCK GKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAG-----AA
Mvan_1264|M.vanbaalenii_PYR-1 GKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAG-----SA
MSMEG_0868|M.smegmatis_MC2_155 GKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAAT-----TA
TH_3810|M.thermoresistible__bu SRRSFCCSRA----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGGSTAVGG------GAHTGVGGGVNTGVGVGSHVG-------
MLBr_01183|M.leprae_Br4923 TANHDSL-------------------------------------------
MAV_4827|M.avium_104 GFGGGHAPAPGGGLGG-------GGGHAPAPGGGLGGFGG----------
Mb3420|M.bovis_AF2122/97 GGAGGVG-------------ATGGNAGSGIG--------PASVGGNGGKG
Rv3388|M.tuberculosis_H37Rv GGAGGVG-------------ATGGNGGSGIG--------PASVGGNGGKG
MMAR_1208|M.marinum_M GGTGGAGGV--GGASDFQFAGSGGSGGTGGA--------AGWLIGNGGSG
MUL_4367|M.ulcerans_Agy99 GGAGGAGVNG-VGGGDGGKGGTGGAGGAGGAGSDGIIPSNGGLGGNGGNG
Mflv_5091|M.gilvum_PYR-GCK GAAGSAG-----------TTGAQGSAGTNGA--------NGANGSQGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GVAGSAG-----------TTGAQGSAGTNGA--------NGANGSQGAAG
MSMEG_0868|M.smegmatis_MC2_155 GATGGAGGFSNIAAIHGAITDSTAISGHGGAG-------NGGNGGKGADG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------GGISESLGG--------SGSVGGSTAVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------GHSG-------------GGLGGLGGGH
Mb3420|M.bovis_AF2122/97 G---------VGAAGGLAG----------QIG--NGGSGGSGGAG-----
Rv3388|M.tuberculosis_H37Rv G---------VGAAGGLAG----------QIG--NGGSGGSGGAG-----
MMAR_1208|M.marinum_M G---------QGGLAGTAD----------PVTGLFGGTGGAGGAGGAAGW
MUL_4367|M.ulcerans_Agy99 GNGGQAFGDGVGGAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLGGATED
Mflv_5091|M.gilvum_PYR-GCK KAG-------ATGTTGATG------------AAGEDGDAGSGGSG-----
Mvan_1264|M.vanbaalenii_PYR-1 KAG-------ATGTTGATG------------AAGDAGDPGSEAVD-----
MSMEG_0868|M.smegmatis_MC2_155 WVQ-------AYDPAGPVGS----KIANSSAVAGNGGDGGVNGTGG----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G----------GAHTSAIN----------------DALGGSGSVG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 K-------------------------------------------------
Mb3420|M.bovis_AF2122/97 ------GNGGTGDTAGN--------------GGNGGAGAVGGNAQLIGNG
Rv3388|M.tuberculosis_H37Rv ------GNGGTGDTAGN--------------GGNGGAGAVGGNAQLIGNG
MMAR_1208|M.marinum_M ----LYGAGGSGGAGGAGTAS----VYPGLSGGNGGNGGNGGAAQVIGNG
MUL_4367|M.ulcerans_Agy99 GVGGVGCAGGAGGNGGRGDML----FTVGGSGGTGGDGGGGGSASGSGTG
Mflv_5091|M.gilvum_PYR-GCK ------INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE----
Mvan_1264|M.vanbaalenii_PYR-1 ------INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE----
MSMEG_0868|M.smegmatis_MC2_155 ------ASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------GSTAVGGG-----------AHTSAINESMNSSINASHSSSM
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 GN--GGGGGNGGTGATPGTGGAGAAGGTGGTLFG--APGTTGADGT----
Rv3388|M.tuberculosis_H37Rv GN--GGGGGNGGT----------------------------GADGT----
MMAR_1208|M.marinum_M GS--GGTAGTGGAGGPDDPPNNIPAGTDG-------QDGAGGAGGSGGLV
MUL_4367|M.ulcerans_Agy99 GS--GGTGGVGGIGGDGKLGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLG
Mflv_5091|M.gilvum_PYR-GCK ----GGAGGGGGAGGSGAGGAG--GAGGS--------GGSGGSGGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1 ----GGAGGSGGAGGSGTGGAG--GAGGS--------GGSGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 GNGAGGAGGNGGTGGTTAGGSGNGGNGGN--------GGNGGADGTPGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NESFGSSMGSHGAAGTGFEAQG---------------HAQGHASETAHTT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3420|M.bovis_AF2122/97 ---------------------
Rv3388|M.tuberculosis_H37Rv ---------------------
MMAR_1208|M.marinum_M FGDSGG---------------
MUL_4367|M.ulcerans_Agy99 GTGAGGAPSDKGINGEPGNPG
Mflv_5091|M.gilvum_PYR-GCK GAAGDSDD-------------
Mvan_1264|M.vanbaalenii_PYR-1 GAAGDSD--------------
MSMEG_0868|M.smegmatis_MC2_155 GTTGANNP-------------
TH_3810|M.thermoresistible__bu ---------------------
MAB_4284c|M.abscessus_ATCC_199 LPGAEHH--------------
MLBr_01183|M.leprae_Br4923 ---------------------
MAV_4827|M.avium_104 ---------------------