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SVFGSAWFYWAVGIAAALPVLVVILTEVQRLLRRRQSALARQVGLLRNYVLPLGALLLLMVNATGVPAHD TAVRLLATVFGFLVLVLLLSGLNAAVFSGAPQGSWRRRLPVIFVDVARFVLIGAGLAVILSFVWGVRIGG LFTALGVTSVVIGLMLQNSVSQIVSGLFMLFEQPFQIDDWLDTTTTRGRIVEVNWRAVHIETGSGLRITP NSVLASTPFTNLSRPAGAYQLAIPTKFSDADAPDRVCALLSRVAAALPQLDGGFLVTTEPVGGTEYCTTI GLRSPAEESAARATFLRWIWYAARREGLHLNGADDDFSTTERVQHALKTVVAPVMRLSDTDQQALLSSAR IIRFAAGETMEYAGQVPAGMTFLITGRVRLTATAEDGSVVPVTTLHEGGFLGLTALTRQPNLAGAHALDE VTALEVDREHLEHLVMREPLLLQDFGHILEERQSKVRRVGGLN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3754 | - | - | 100% (464) | hypothetical protein MMAR_3754 |
| M. marinum M | MMAR_3756 | - | e-173 | 65.43% (460) | hypothetical protein MMAR_3756 |
| M. marinum M | MMAR_3542 | - | 2e-07 | 25.09% (291) | hypothetical protein MMAR_3542 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2460c | - | 1e-175 | 65.58% (459) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_2744 | - | 7e-07 | 27.78% (162) | MscS mechanosensitive ion channel |
| M. tuberculosis H37Rv | Rv2434c | - | 1e-175 | 65.58% (459) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3477c | - | 4e-06 | 29.20% (113) | MscS mechanosensitive ion channel |
| M. avium 104 | MAV_3202 | - | 1e-170 | 65.36% (459) | transmembrane protein |
| M. smegmatis MC2 155 | MSMEG_3579 | - | 1e-149 | 55.80% (457) | transmembrane protein |
| M. thermoresistible (build 8) | TH_2299 | - | 1e-149 | 56.95% (453) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3697 | - | 0.0 | 99.14% (464) | hypothetical protein MUL_3697 |
| M. vanbaalenii PYR-1 | Mvan_3795 | - | 3e-07 | 27.78% (162) | MscS mechanosensitive ion channel |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3754|M.marinum_M --MSVFGSAWFYWAVGIAAALPVLVVILTEVQRLLRRRQSALARQVGLLR
MUL_3697|M.ulcerans_Agy99 --MSVFGSAWFYWAVGIAAALPVLVVILTEVQRLLRRRQSALARQVGLLR
Mb2460c|M.bovis_AF2122/97 --MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLR
Rv2434c|M.tuberculosis_H37Rv --MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLR
MAV_3202|M.avium_104 --MSTFDSSSLYWATAVVFGLPLLLIVLTEWHQSLVRKHSPLARPAFLLR
MSMEG_3579|M.smegmatis_MC2_155 -MRSVLEANWFYWALSVAVGLPIGLVLLTELHNTLARHGSYLARPVSLLR
TH_2299|M.thermoresistible__bu -VSLALDGAWLYWAIGVAVGFPAALILLTELHDAMVRRNSIMARPVQLLR
Mflv_2744|M.gilvum_PYR-GCK MDVSSLAFEWTDTSRHWLIEVPIRIVVYIAVALVIRYLVHRMIDRATTGR
Mvan_3795|M.vanbaalenii_PYR-1 MDVSLLAFEWTDTSRHWLIEVPIRIVAYLTVALVIRFVVHRMIDRATTSR
MAB_3477c|M.abscessus_ATCC_199 -----MIRAAEFSAGGLRLAERWNSFWSSQIGRWLLDNG-----------
: : . :
MMAR_3754|M.marinum_M NYVLPLGALLLLMVNATGVPAHDTAVRLLATVFGFLVLVLLLSGLNAAVF
MUL_3697|M.ulcerans_Agy99 NYVLPLGALLLLLVNATGVPAHDTAVRLLATVFGFLVLVLLLSGLNAAVF
Mb2460c|M.bovis_AF2122/97 NYLLPLGAVLLLLVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLF
Rv2434c|M.tuberculosis_H37Rv NYLLPLGAVLLLLVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLF
MAV_3202|M.avium_104 SYLIPLGALLVLLVNVARMPAQFTSVRVLATAFGFVVVVLLLSGLNATIF
MSMEG_3579|M.smegmatis_MC2_155 NYILPLAALLILLVKGSEISAEATPVRIVATGFGFVVIILLLSGLNATLF
TH_2299|M.thermoresistible__bu NYLLPLAALLILLVQAVEVSTEATPVRIVATAFSFAVLILLLSGLNATLF
Mflv_2744|M.gilvum_PYR-GCK ------------TRKNRGGGEDARPQRTPPLVRRLRDRVPSSTTSEQIIA
Mvan_3795|M.vanbaalenii_PYR-1 ------------TRKDK----DAAGARTPPLVRKLRDRVPSSASSEQVIA
MAB_3477c|M.abscessus_ATCC_199 ------------LQIVIAILGAMILVRFINWGAQKITRRLDRSFTQSDAL
* : :
MMAR_3754|M.marinum_M SGAPQGSWRRRLPVIFVDVARFVLIGAGLAVILSFVWGVRIGGLFTALGV
MUL_3697|M.ulcerans_Agy99 SGAPQGSWRRRLPVIFVDVARFVLIGAGLAVILSFVWGVRIGGLFTALGV
Mb2460c|M.bovis_AF2122/97 QGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYIWGVRVGGLFAALGV
Rv2434c|M.tuberculosis_H37Rv QGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYIWGVRVGGLFAALGV
MAV_3202|M.avium_104 EGAPEGSWRQRVPGIFLDVTRFVLIGVGLAVIFSYVWGVRVGGLFTALGV
MSMEG_3579|M.smegmatis_MC2_155 QGAPEGSWRKRIPSIFLDVARFALIAVGVGMIMAYVWGANVGGLFTALGV
TH_2299|M.thermoresistible__bu HGAPEDTWRKRIPTIFVDVARFALIAVGLALILAYIWGANVGGLFTALGV
Mflv_2744|M.gilvum_PYR-GCK R---RQQRAQTIGSVLKSTVSIVLLVWVVLAVLN-VVGVNIAPFIASAGV
Mvan_3795|M.vanbaalenii_PYR-1 R---RQQRAQTIGSVLKSTVSIVLLVWVVLAVLN-VLGVNIAPFIASAGV
MAB_3477c|M.abscessus_ATCC_199 VRSEASKHRQALASVISWIIVVLVVVLTTVHVVG-VLGISVGGLAGPAAV
: : :: . :: :. : * :. : . .*
MMAR_3754|M.marinum_M TSVVIGLMLQNSVSQIVSGLFMLFEQPFQIDDWLDT------TTTRGRIV
MUL_3697|M.ulcerans_Agy99 TSVVIGLMLQNSVSQIVSGLFMLFEQPFQIDDWLDT------TTTRGRIV
Mb2460c|M.bovis_AF2122/97 TSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLET------PTARGRVV
Rv2434c|M.tuberculosis_H37Rv TSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLET------PTARGRVV
MAV_3202|M.avium_104 TSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGDWLDT------PAARGRIV
MSMEG_3579|M.smegmatis_MC2_155 TSIVLGLALQNAVGQIISGLLLLFEQPFQLGDWLDT------PSARGRVV
TH_2299|M.thermoresistible__bu SSIVLGLALQNAVGQIVSGLLVLFEQPFQIGDWVDT------PSARGKVV
Mflv_2744|M.gilvum_PYR-GCK VGLAIGFGAQNLVRDFVTGVFMLLEDQYGVGDTVDL------GEAVGEVE
Mvan_3795|M.vanbaalenii_PYR-1 VGLAIGFGAQNLVRDFVTGVFMLLEDQYGVGDTVDL------GEAVGEVE
MAB_3477c|M.abscessus_ATCC_199 LGGALGFGAQRVVQDLLSGFFLITEKQYGFGDLVELYVQGQTTESRGTVE
. .:*: *. * ::::*.::: *. : ..* :: : * :
MMAR_3754|M.marinum_M EVNWRAVHIETGSGLRITPNSVLASTPFTNLSRPAGAYQLAIPTKFSDAD
MUL_3697|M.ulcerans_Agy99 EVNWRAVRIETGSGLRITPNSVLASTPFTNLSRPAGAYQLAIPTKFSDAD
Mb2460c|M.bovis_AF2122/97 EVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSD
Rv2434c|M.tuberculosis_H37Rv EVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSD
MAV_3202|M.avium_104 EANWRSVHIQTGHGLQITPNSVLATTSFTNLSRPPGGHQLTLTATFSETD
MSMEG_3579|M.smegmatis_MC2_155 EVNWRATHIDTGGGLQIMPNSVLAGASFTNLSRPEAAHSLSVTTTFGVSD
TH_2299|M.thermoresistible__bu EVNWRATHIDTGGGLRVIPNSELADASFTNLSRPPGTHTITVPTVFAGGD
Mflv_2744|M.gilvum_PYR-GCK SVGLRITTVRDIDGT-----------------------------------
Mvan_3795|M.vanbaalenii_PYR-1 SVGLRITTVRDIDGT-----------------------------------
MAB_3477c|M.abscessus_ATCC_199 EVTLRVTKLRSGDGE-----------------------------------
.. * . : *
MMAR_3754|M.marinum_M APDRVCALLSRVAAALPQLDGGFLVTTEPVGGTEYCTTIGLRSPAEESAA
MUL_3697|M.ulcerans_Agy99 APDRVCALLSRVAAALPQLDGGFLVTTEPVGGTEYCTTIGLRSPAEESAA
Mb2460c|M.bovis_AF2122/97 PPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPT
Rv2434c|M.tuberculosis_H37Rv PPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPT
MAV_3202|M.avium_104 PPDRVCALLRRVADALPQRRPDAVAAAVPAGGGEYHVTIGLTSPADDSAA
MSMEG_3579|M.smegmatis_MC2_155 SPDAVCALLTRVATQLPQRRAGAAPKAIPLGAGEYKTSIPLRTPADDSAA
TH_2299|M.thermoresistible__bu APDQVCAMLTRVAANLPQLLPGAEPSAAPAGRGEYRTSIPLRTPADDATA
Mflv_2744|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3795|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3477c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3754|M.marinum_M RATFLRWIWYAARREGLHLNGADDDFSTTERVQHALKTVVAPVMRLSDTD
MUL_3697|M.ulcerans_Agy99 RATFLRWIWYAARREGLHLNGADDDFSTTERVQHALKTVVAPVMRLSDTD
Mb2460c|M.bovis_AF2122/97 QATFLRWVWYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSD
Rv2434c|M.tuberculosis_H37Rv QATFLRWVWYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSD
MAV_3202|M.avium_104 QATLLRWLWYGARREGLRLDGAEDDISTPERIERALRMVVAPALRLGPPD
MSMEG_3579|M.smegmatis_MC2_155 RAVFLRWLWYAARRAELHLDGETDDFSTPERLTKAVR-QMAPTLRLSHTE
TH_2299|M.thermoresistible__bu RSTFLRWVWYAARRAGLHLDRSTDDFVTTERLTTALA-AIAPALRLSEAE
Mflv_2744|M.gilvum_PYR-GCK -------LWYVRNGEIARVGNMSQEYAVAR--------------------
Mvan_3795|M.vanbaalenii_PYR-1 -------LWYVRNGEIARVGNMSQEYAVAR--------------------
MAB_3477c|M.abscessus_ATCC_199 -------VITIPNGLIVKAVNLSKDWARAVVDIPVPT---SVDLARVNDV
: . : .: .
MMAR_3754|M.marinum_M QQALLSSARIIRFAAGETMEYAGQVPAGMTFLITGRVRLTATAEDGSVVP
MUL_3697|M.ulcerans_Agy99 QQALLSSARIIRFAAGDTMEYAGQVPAGMTFLITGRVRLTATAEDGSIVP
Mb2460c|M.bovis_AF2122/97 QQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVA
Rv2434c|M.tuberculosis_H37Rv QQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVA
MAV_3202|M.avium_104 QQALVSHARIVRYGADEIVEHAGRVPEKMTFLLAGGVRLTATAPDGSVVA
MSMEG_3579|M.smegmatis_MC2_155 QQEVLNHSALVRFGADEIIQEAGEIPTRMSFIVSGRVGVSVAGDGDAVIP
TH_2299|M.thermoresistible__bu QQDLLPRAGIARYGAGEPIQVAGEVPSHMTFVVRGRVRVVAPLADGSAVE
Mflv_2744|M.gilvum_PYR-GCK ------------------IEVPVALSADIERAEQVAVEAAEAAVAEKSLA
Mvan_3795|M.vanbaalenii_PYR-1 ------------------IEVPVALTADVDRAEQVAHEAAQEAVADPALA
MAB_3477c|M.abscessus_ATCC_199 LYDVCQQALVDRDLSQLLLDAPSLMGVESIEVDRVNVRMVARTLPGKQFE
:: . : .
MMAR_3754|M.marinum_M VTTLHEGGFLGLTALTRQPNLAGAHALDEVTALEVDREHLEHLVMREPLL
MUL_3697|M.ulcerans_Agy99 VTTLHEGGFLGLTALTRQPNLAGAHALDEVTALEVDREHLEHLVMREPLL
Mb2460c|M.bovis_AF2122/97 IATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPML
Rv2434c|M.tuberculosis_H37Rv IATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPML
MAV_3202|M.avium_104 VGGLDEGSFLGVTALTRQPNLADAQAVAEVTALEIDREHLVELVTGKPLL
MSMEG_3579|M.smegmatis_MC2_155 VRTLTENDFLGQTALTREGALASAHALTETTVLQISREFLEELVAGNPLL
TH_2299|M.thermoresistible__bu VRIAGPGDFLGQSTLTREPVSTSAYAVDEVTVVELERTVLEDLVTRKPVL
Mflv_2744|M.gilvum_PYR-GCK GKVLGEPEMLGVQELS-----PDLIKLRMTVKVRPNAQWAVQRRLRRAIL
Mvan_3795|M.vanbaalenii_PYR-1 GKVIGEPEMLGVQELS-----PDLIKLRMTVKVRPNAQWAVQRKLRRAIL
MAB_3477c|M.abscessus_ATCC_199 VGRRLRAKVIAALAKAGVALVGDSRPTVRTMSSSGSGELKREGKREDAKR
.:. : . . . .
MMAR_3754|M.marinum_M LQDFGHILEERQSKVRRVGGLN-----------------
MUL_3697|M.ulcerans_Agy99 LQDFGHILEERQSKVRRVGGLN-----------------
Mb2460c|M.bovis_AF2122/97 LQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR
Rv2434c|M.tuberculosis_H37Rv LQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR
MAV_3202|M.avium_104 LQDLGRTIDERRALVHRAVTAEPTPSREPVS--------
MSMEG_3579|M.smegmatis_MC2_155 LLELSRIIDDRRSAARAALTAD-----------------
TH_2299|M.thermoresistible__bu LQDIGRAIEERRLMARRAVTTQR----------------
Mflv_2744|M.gilvum_PYR-GCK QAYDEHGIALPYPNGRVHAVGE-----------------
Mvan_3795|M.vanbaalenii_PYR-1 RAYDEHGIDLPYPGGRMQVAAASE---------------
MAB_3477c|M.abscessus_ATCC_199 DEVKREEEGVDTKPQPIVQAEELT---------------
.