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MSFAVVAPELMRVAASDLANIGSTLSAANAVAAAQTTAVQAAAADEVSTAIAALFGWHAQTYQSLSAQAT SFHDQFVQTLASSGTSYWSAEATNVEQTLLNAINAPTEALFGRPLIGDGADGQTVNGVGQAGGDGGFLWG NGGNGGDSTSAGVAGGAGGSAGLFGNGGAGGTGADADVSATNGGAGGAGGNAGLIFGFGGAGGTGGSGIN SFASFGGDGGAGGNSYLLGAAGAGGNGGVGLGTSGFGGTGGDGGQGGLFGNGAAGGLGGQSTDGDGGSGG SGGRAGILYGDGGDGGDGGAGRFSSGSGGAAGTAILAGNGGSGGNGASSTATSGDGFGGFGGIGGTGGLF FGNGGDGGNGGDGFDVANGGGWGSSGGSALLFGDGGAGGNGGAGGGQGANGGLGGLVIGNGGNGGIGGAG DSGNPAGGQGGNGGGAYLIGNGGWGGVGGAGDGTGDGGDGGSGGDGGWLLGNGGNGAEGGTSSATGGAGG NGGDARFIGDGGDGAHGGDGTPDGASGTGGSGGILFGQNGSDGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3728 | - | - | 100% (534) | PE-PGRS family protein, PE_PGRS2 |
| M. marinum M | MMAR_2645 | - | e-147 | 50.87% (631) | PE-PGRS family protein |
| M. marinum M | MMAR_4223 | - | e-146 | 50.00% (616) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1797 | PE_PGRS31 | 1e-150 | 50.16% (630) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 8e-87 | 48.51% (435) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1768 | PE_PGRS31 | 1e-151 | 50.16% (624) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-10 | 32.61% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-45 | 35.55% (391) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-19 | 39.44% (180) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-80 | 36.39% (643) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-40 | 41.13% (282) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3671 | - | 0.0 | 79.46% (448) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-85 | 47.53% (425) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3728|M.marinum_M --------------------------------------------------
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3728|M.marinum_M --------------------------------------------------
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3728|M.marinum_M --------------------------------------------------
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3728|M.marinum_M --------------------------------------------------
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3728|M.marinum_M --------------------------------------------------
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
MMAR_3728|M.marinum_M ----------MSFAVVAPELMRVAASDLANIGSTLSAANAVAAAQTTAVQ
MUL_3671|M.ulcerans_Agy99 ----------MSFAVVAPELMRVAASDLANIGSTLSAANAVAAAQTTAVQ
Mb1797|M.bovis_AF2122/97 ----------MSYLVVVPELVAAAATDLANIGSSISAANAAAAAPTTALV
Rv1768|M.tuberculosis_H37Rv ----------MSYLVVVPELVAAAATDLANIGSSISAANAAAAAPTTALV
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 ---------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIA
MAB_4284c|M.abscessus_ATCC_199 ---MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPV
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
MMAR_3728|M.marinum_M AAAADEVSTAIAALFGWHAQTYQSLSAQATSFHDQFVQTLASSGTSYWSA
MUL_3671|M.ulcerans_Agy99 AAAADEVSTAIAALFGWHAQTYQSLSAQATSFHDQFVQTVASSGTSYWSA
Mb1797|M.bovis_AF2122/97 AAGGDEVSAAIAALFGAHARAYQALSAQAAMFHEQFVRALAAGGNSYAVA
Rv1768|M.tuberculosis_H37Rv AAGGDEVSAAIAALFGAHARAYQALSAQAAMFHEQFVRALAAGGNSYAVA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923 PPAADDVSILLAHFFSGHGRQYQAHAS---------------QGATNHQD
MAB_4284c|M.abscessus_ATCC_199 VAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSP
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
. .
MMAR_3728|M.marinum_M EAT---NVEQTLLNAINAPTEALFGRPLIGDGADGQ--------------
MUL_3671|M.ulcerans_Agy99 EAT---NVEQTLLNAINAPTEALFGRPLIGDGADGQ--------------
Mb1797|M.bovis_AF2122/97 EAATAQSVQQDLLNLINAPTQALLGRPLIGNGANG---------------
Rv1768|M.tuberculosis_H37Rv EAATAQSVQQDLLNLINAPTQALLGRPLIGNGANG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MLBr_01183|M.leprae_Br4923 LIQ---------------------SLLTSSSAYAG---------------
MAB_4284c|M.abscessus_ATCC_199 RDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN--------------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP-------------
MMAR_3728|M.marinum_M -----TVNGVGQAGGDGGFLWGNGGNGGDSTSAG----------------
MUL_3671|M.ulcerans_Agy99 -----TVNGVGQAGGDGGFLWGNGGNGGDSTSAG----------------
Mb1797|M.bovis_AF2122/97 ------LPGTGQNGGDGGILYGNGGNGG-SGGVN----------------
Rv1768|M.tuberculosis_H37Rv ------LPGTGQNGGDGGILYGNGGNGG-SGGVN----------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSN----------------
MAV_4827|M.avium_104 DVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPG----------------
MMAR_3728|M.marinum_M ------VAGGAGGSAGLFGNGGAGGTGADADVSATNGGAGGAGGNAGLIF
MUL_3671|M.ulcerans_Agy99 ------VAGGAGGSAGLFGNGGAGGTGADADVSATNGGAGGAGGNAGLIF
Mb1797|M.bovis_AF2122/97 ------QAGGNGGNAGLWGNGGSGGAGGNATTAGRNGFNGGAGGSGGLLW
Rv1768|M.tuberculosis_H37Rv ------QAGGNGGNAGLWGNGGSGGAGGNATTAGRNGFNGGAGGSGGLLW
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MLBr_01183|M.leprae_Br4923 --------TETANHDSL---------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------SGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDY
MAV_4827|M.avium_104 ------GLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAA
MMAR_3728|M.marinum_M GFGGAGGTGGSG------------------INSFASFGGDGGAGGNS-YL
MUL_3671|M.ulcerans_Agy99 GFGGAGGTGGSG------------------INSFASFGGDGGAGGNS-YL
Mb1797|M.bovis_AF2122/97 GNGGAGGAGGHGGPAPL-------------VGGVGTTGGAGGNGGGAGLF
Rv1768|M.tuberculosis_H37Rv GNGGAGGAGGNGGPAPL-------------VGGVGTTGGAGGNGGGAGLF
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGGAGGWG--------------------GSGVDG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTE
MAV_4827|M.avium_104 ANAPLFASSTAA-------------------LAYAQDPGTGAVDQYSLPD
MMAR_3728|M.marinum_M LGAAG------AGGNGGVG-------------------------------
MUL_3671|M.ulcerans_Agy99 LGAAG------AGGNGGVG-------------------------------
Mb1797|M.bovis_AF2122/97 YGFGG------AGGNGGMGGVA--------------------------PS
Rv1768|M.tuberculosis_H37Rv YGFGG------AGGNGGMGGVA--------------------------PS
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu -----------VDVVGG---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IGSHNQANIGTSTSAGGSAAVG----------------------------
MAV_4827|M.avium_104 YLYVP------VDPEPGDD-------------------------------
MMAR_3728|M.marinum_M ----LGTSGFGGTGGDGGQGG----------------------LFGNG--
MUL_3671|M.ulcerans_Agy99 ----LGTSRFGGTGGDGGQGG----------------------LFGNG--
Mb1797|M.bovis_AF2122/97 TGPSMGILPAGGVGGPGGSGGASAL------------------AFGSGGV
Rv1768|M.tuberculosis_H37Rv TGPSMGILPAGGVGGPGGSGGASAL------------------AFGSGGV
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GNAGLAGNAGLAGNAGLAGNAG-------------------LAGNAGL
MAV_4827|M.avium_104 ---ELAYSAVGEEDAESPTVVIEKLFLP---------------EDSEPRR
MMAR_3728|M.marinum_M -AAGGLGG------------------------------------------
MUL_3671|M.ulcerans_Agy99 -AAGGLGG------------------------------------------
Mb1797|M.bovis_AF2122/97 GGAGGLGGPTDGTV------------------------------------
Rv1768|M.tuberculosis_H37Rv GGAGGLGGPTDGTV------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAG------------------------------------
MAV_4827|M.avium_104 RPVLLVGSGLAVVG------------------------------------
MMAR_3728|M.marinum_M -----------QSTDGDGGSGGSGGRAGILYGDGGD------------GG
MUL_3671|M.ulcerans_Agy99 -----------QSTDGDGGSGGSGGRAGILYGDGG---------------
Mb1797|M.bovis_AF2122/97 -----------QGVGGFGGQGGNGGQSGLLFGNAGA------------GG
Rv1768|M.tuberculosis_H37Rv -----------QGVGGFGGQGGNGGQSGLLFGNAGA------------GG
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------NAGLAGNAGLAGNAGLAGNAGLAGNAG-------------
MAV_4827|M.avium_104 -----ISAVLALEIALAIGIRTTGTVALQPTPNQHLIVP-----------
MMAR_3728|M.marinum_M DGGAGRFSS----------GSGGAAGTAILAGNGG-------SGGNGASS
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 AGAAGGAGTGDTESFGGHGGAGGDGGAVGLIGNGGGGGNGGAGGTGSPGA
Rv1768|M.tuberculosis_H37Rv AGAAGGAGTGDTESFGGHGGAGGDGGAVGLIGNGG------AGGTGSPGA
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE------GEGGTGGHG
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---------GGNGSHG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG----NAGLAGNAGLA
MAV_4827|M.avium_104 --TEQAPAPPPVQASAPQPKISVPEPVAAPKPLSP--------PVAAPLP
MMAR_3728|M.marinum_M TATSGDGFGGFGGIGGTGGLFFGNGGDGGNGGDGFD--------VANGGG
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 VVGGNGGVGGLGGAGSPGGLLYGTGGAGGNGGPGGDGGTGATVGFAGSGG
Rv1768|M.tuberculosis_H37Rv VVGGNGGVGGLGGAGSPGGLLYGTGGAGGNGGPGGDGGTGATVGFAGSGG
Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGG
TH_3810|M.thermoresistible__bu GNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAAVAG----NAAVAGNAAVAGNAAVGGVLNTGVSGA
MAV_4827|M.avium_104 AAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQ
MMAR_3728|M.marinum_M WGSSGGSALL---------FGDGGAGGNGGAG------------------
MUL_3671|M.ulcerans_Agy99 ---------------------------NGGAG------------------
Mb1797|M.bovis_AF2122/97 FGGAGGIAQL---------FGTGGMGGSGGGIGAGTTTVVPPDVAP----
Rv1768|M.tuberculosis_H37Rv FGGAGGIAQL---------FGTGGMGGSGGGIGAGTTTVVPPDVAP----
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu DGGNGGDG---------------GNGGSAG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IGGSSHVGGAIN-------ESLGGSGSVGGSTAVGG--------------
MAV_4827|M.avium_104 LLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEG----
MMAR_3728|M.marinum_M --------------GGQGANGGLGGLVIGNG-------------------
MUL_3671|M.ulcerans_Agy99 --------------GGQGANGGLGGLVIGNG-------------------
Mb1797|M.bovis_AF2122/97 -------------VGGTGGNGGRAGLLLGVG-------------------
Rv1768|M.tuberculosis_H37Rv -------------VGGTGGNGGRAGLLLGVG-------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu -------------RGGTGGLRGVFGINGGNG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------GAHTGVGGGVSTGVGVG-------------------
MAV_4827|M.avium_104 ---------TPPKPDGPGNYGGGHVPTPGAG-------------------
MMAR_3728|M.marinum_M -------GNGGIGGAGDSGNP--AGGQG----------GNGG-GAYLIGN
MUL_3671|M.ulcerans_Agy99 -------GNRGIGGAGDSGNP--AGGQG----------GNGG-GAYLIGN
Mb1797|M.bovis_AF2122/97 -------GMGGNGGATSVGGT--LYAAG----------GNGGDGGLVWGN
Rv1768|M.tuberculosis_H37Rv -------GMGGNGGATSVGGT--LYAAG----------GNGGDGGLVWGN
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL
TH_3810|M.thermoresistible__bu -----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----SHVGGGISESLGGSGSVGGSTAVG---------------GGAHTGV
MAV_4827|M.avium_104 ------GSGGSGGGHVPTPGAGGSGGSG----------GGHVPTPGTGGP
MMAR_3728|M.marinum_M GGWGGVGGAGDGTGDGGDGGSGGDGGWLLG--------------------
MUL_3671|M.ulcerans_Agy99 GGWGGVG------------GSGGDGGWLLG--------------------
Mb1797|M.bovis_AF2122/97 GGTGGSGGAG-GAGSVGNGGAGGNAALLFG--------------------
Rv1768|M.tuberculosis_H37Rv GGTGGSGGAG-GAGSVGNGGAGGNAALLFG--------------------
Mflv_5091|M.gilvum_PYR-GCK GGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GS
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQS
TH_3810|M.thermoresistible__bu GGTPSAGFGVPTTIQFPAGSCTSRAVSREG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGVSTGVGVGSHVGGGISESLGGSGSVGG--------------------
MAV_4827|M.avium_104 GGTGGSGGGHVPTPGAGTPGGSGGGHLPFP--------------------
MMAR_3728|M.marinum_M ---------NGGNGAEG-----------------------GTSSATG--G
MUL_3671|M.ulcerans_Agy99 ---------NGGNGAEG-----------------------GTSSATG--G
Mb1797|M.bovis_AF2122/97 ---------NGGAGGAGGAGGIGAGGAGGFGAVLFGNGGAGGSGAPGGIG
Rv1768|M.tuberculosis_H37Rv ---------NGGAGGAGGAGGIGAGGAGGFGAVLFGNGGAGGSGAPGGIG
Mflv_5091|M.gilvum_PYR-GCK GSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASG
MSMEG_0868|M.smegmatis_MC2_155 GYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTA
TH_3810|M.thermoresistible__bu ----IMPSSRAASARAG---------------------------AACASS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----STAVGGGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGGSTA
MAV_4827|M.avium_104 ---------GAGSTPGGSGGG----------------HLPTPGAGTPGGG
MMAR_3728|M.marinum_M AGGNGGDARFIGD-------------------------------------
MUL_3671|M.ulcerans_Agy99 DGGNGGDARFIGN-------------------------------------
Mb1797|M.bovis_AF2122/97 AGGNGGNALLVGN-------------------------------------
Rv1768|M.tuberculosis_H37Rv AGGNGGNALLVGN-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
Mvan_1264|M.vanbaalenii_PYR-1 AQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
TH_3810|M.thermoresistible__bu TSRSRRSFCCSRA-------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTSAINDALGGSG--------------------------------
MAV_4827|M.avium_104 LGGFGGGHAPAPG-------------------------------------
MMAR_3728|M.marinum_M --------------------------------------------------
MUL_3671|M.ulcerans_Agy99 --------------------------------------------------
Mb1797|M.bovis_AF2122/97 --------------------------------------------------
Rv1768|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-
Mvan_1264|M.vanbaalenii_PYR-1 GAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155 GADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3728|M.marinum_M -----------------GGDGAHGGDGTP--------DGASGTGGSGGIL
MUL_3671|M.ulcerans_Agy99 -----------------GGDGAHGGDGTP--------DGASGTGGSGGIL
Mb1797|M.bovis_AF2122/97 -----------------GGN---GGAGTG--------GAAGGAGGSGGLL
Rv1768|M.tuberculosis_H37Rv -----------------GGN---GGAGTG--------GAAGGAGGSGGLL
Mflv_5091|M.gilvum_PYR-GCK ----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSG
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 TSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------SVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSS
MAV_4827|M.avium_104 -----------------GGLGGGGGHAPAP--------GGGLGGFGGGHS
MMAR_3728|M.marinum_M FGQNGSDGG--------------------------
MUL_3671|M.ulcerans_Agy99 FGQNGSDGG--------------------------
Mb1797|M.bovis_AF2122/97 FGQNGMPGP--------------------------
Rv1768|M.tuberculosis_H37Rv FGQNGMPGP--------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD--
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD---
MSMEG_0868|M.smegmatis_MC2_155 AGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP--
TH_3810|M.thermoresistible__bu -----------------------------------
MLBr_01183|M.leprae_Br4923 -----------------------------------
MAB_4284c|M.abscessus_ATCC_199 MGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 GGGLGGLGGGHK-----------------------