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LIARAPGPLADTARRCRETGVHVRTIAVDLVDPEAVALICSETADLEVGLLIYNAGANTCREQFLDAELT ELGRVIDLNVTRMLELVQHFGRPMRARRRGGIVLVGSTAATYGAMRQSAYAGAKAFSRLFAESLWLELRE TGVDVLELVLGVTRTPAMQRAGLNFDAPGISVSDPADVAREGLDNLANGPVVIAGDNAAHVHRGSGADRA AIVLRAHRAMQALIGSPPPPPKGDRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3509 | - | - | 100% (237) | short-chain alcohol dehydrogenase |
| M. marinum M | MMAR_0648 | - | 1e-12 | 29.90% (194) | ketoacyl reductase |
| M. marinum M | MMAR_3856 | - | 6e-10 | 32.70% (159) | short-chain type dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3199 | - | 2e-10 | 31.58% (190) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4545 | - | 7e-84 | 68.56% (229) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3174 | - | 2e-10 | 31.58% (190) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00429 | - | 6e-10 | 31.85% (157) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1537c | - | 6e-14 | 35.03% (157) | putative short chain dehydrogenase/reductase |
| M. avium 104 | MAV_5238 | - | 5e-31 | 37.50% (232) | oxidoreductase, short-chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_2895 | - | 2e-82 | 68.00% (225) | short chain oxidoreductase |
| M. thermoresistible (build 8) | TH_2749 | - | 1e-81 | 66.81% (226) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0124 | - | 4e-13 | 29.90% (194) | ketoacyl reductase |
| M. vanbaalenii PYR-1 | Mvan_2633 | - | 1e-77 | 65.04% (226) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3509|M.marinum_M -----------------------------------------------MLI
Mflv_4545|M.gilvum_PYR-GCK ---------------MTKYGPWAVIAGGSEGVGAEFAKALAEDGANLVLI
MSMEG_2895|M.smegmatis_MC2_155 ------------MPDLATYGPWAVIAGGSEGVGAEFARLLAEAGVNLVLI
TH_2749|M.thermoresistible__bu ------------VTDLTRYGPTAVIAGGSEGVGAEFARLLADAGIDLVLI
Mvan_2633|M.vanbaalenii_PYR-1 MLPDTRRGDDVTVTDLTGYGPWAVVAGGSEGVGAEFAAQLARAGVNLVLV
MAV_5238|M.avium_104 ------------MSFAARYGPWALVAGASDGVGAAFAEGLAERGVNVALL
MLBr_00429|M.leprae_Br4923 -----------MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVI
MAB_1537c|M.abscessus_ATCC_199 -----------MPIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIIT
MUL_0124|M.ulcerans_Agy99 -----------MPRPV------ALITGPTSGIGAGYARRYAQDGYDLILV
Mb3199|M.bovis_AF2122/97 --------------MTSLAERTALVTGANRGMGREYVAQLLGRKVAKVYA
Rv3174|M.tuberculosis_H37Rv --------------MTSLAERTVLVTGANRGMGREYVAQLLGRKVAKVYA
MMAR_3509|M.marinum_M ARAPGPLADTARRCRETG-VHVRTIAVDLVDPEAVALICSETADLEVGLL
Mflv_4545|M.gilvum_PYR-GCK ARKPQPLDETAQECRRLG-AQVRTIALDLLDADSTSRIVDATSDVEVGLL
MSMEG_2895|M.smegmatis_MC2_155 ARKPGPLQDTAQRCREIG-VDVRTVATDLLDPTAVEQITGATAGLDVGLL
TH_2749|M.thermoresistible__bu ARKPGPLEDTAADCRARG-VEVRTISADLTDPAAVHRVLAECAGLEVGLL
Mvan_2633|M.vanbaalenii_PYR-1 ARTPEPLERTAARCREFG-VQTRTLAVDLVD--ATHEVIAATADLEVGLL
MAV_5238|M.avium_104 ARRQDVLDRVAARIRARTSAQTRTLAIDLAHPGAAKAIAAATADVTIGML
MLBr_00429|M.leprae_Br4923 ARREDVLVDLAARLADKYRVAVEVRPADLTDPSERVKLADELTVRPISIL
MAB_1537c|M.abscessus_ATCC_199 ARRGEILNDLANALSEKTGVIVEVRAVDLADPGARDALCTELSERNISIL
MUL_0124|M.ulcerans_Agy99 ARDVDRLTQSAVELEDDAG-NVEILPADLADAAGRDKVAERLS-RGVRVL
Mb3199|M.bovis_AF2122/97 ATRNPLAIDVS---------DPRVIPLQLDVTDAVSVAEAADLATDVGIL
Rv3174|M.tuberculosis_H37Rv ATRNPLAIDVS---------DPRVIPLQLDVTDAVSVAEAADLATDVGIL
* : . . :* : :*
MMAR_3509|M.marinum_M IYNAGANTCREQFLDAELTELGRVIDLNVTRMLELVQHFGRPMRARRRGG
Mflv_4545|M.gilvum_PYR-GCK IYNAGASTCNERFLDAELSEFGKVIDLNTTRMLELTQHFGRRMAAMSRGG
MSMEG_2895|M.smegmatis_MC2_155 IYNAGASTCNEPFLDAPLDDFRKVLDLNVTRMMELVQHYARPMVARQRGG
TH_2749|M.thermoresistible__bu IYNAGANTCSEEFLDGELADFDKVLRLNIDTMLTLVQHFGRPMRERRSGG
Mvan_2633|M.vanbaalenii_PYR-1 IYNAGANTCSEEFLDADLAEFGRVVDLNVTAMMTLVQHYGRPMRERRRGG
MAV_5238|M.avium_104 VYCAGADPDFKPFLANRIEAAEAMVQRNCMVPMQLCHHYAPAMVERGAGG
MLBr_00429|M.leprae_Br4923 CANAGTATF-GPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGG
MAB_1537c|M.abscessus_ATCC_199 CNNAGTATF-GPIRGLDPAGERKQVQLNAVAVHDLTLAVLPGMLARGAGG
MUL_0124|M.ulcerans_Agy99 VNNAGFATS-GEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGT
Mb3199|M.bovis_AF2122/97 INNAGISRA-SSVLDKDTSALRGELETNLFGPLALASAFADRIAER-SGA
Rv3174|M.tuberculosis_H37Rv INNAGISRA-SSVLDKDTSALRGELETNLFGPLALASAFADRIAER-SGA
** . : * * : *
MMAR_3509|M.marinum_M IVLVGSTAATYGAMRQSAYAGAKAFSRLFAESLWLELRETGVDVLELVLG
Mflv_4545|M.gilvum_PYR-GCK IVLVGSLSGYMGAERHSVYAGAKAFSRVFAESLWLELREHGVDVLELVLG
MSMEG_2895|M.smegmatis_MC2_155 VLIVGSLSGYMGADRHSVYGGAKAFSRIFAESLWLELREHNVDVVELVLG
TH_2749|M.thermoresistible__bu ILLVGSMAGYLGSARHTVYGGVKAFGRIFAESLWLELRDHGVDVLELVLG
Mvan_2633|M.vanbaalenii_PYR-1 ILLVGSMAGYLGSVRHTVYGGVKAFGRIFAEGLWLELRDHDVHVLELVLG
MAV_5238|M.avium_104 IVLFGSGAGLAGGPNMVAYGASKAFDMVFAEALWAELHDKGVDVLGLILG
MLBr_00429|M.leprae_Br4923 ILISGSAAGNSPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPG
MAB_1537c|M.abscessus_ATCC_199 ILISGSAAGNSPIPNNATYAATKAFANTFSESLRGELKGTGVHVTLLAPG
MUL_0124|M.ulcerans_Agy99 VINIASVAG-LLSGRGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPG
Mb3199|M.bovis_AF2122/97 IVNVSSVLAWLPLG--MSYGVSKAAMWSATESMRIELAPRGVQVVGVYVG
Rv3174|M.tuberculosis_H37Rv IVNVSSVLAWLPLG--MSYGVSKAAMWSATESMRIELAPRGVQVVGVYVG
:: .* . *. ** :*.: * .* * : *
MMAR_3509|M.marinum_M VTRTPAMQRAGLN---FDAPGISVSDPA---DVAREGLDNLANGPVVIAG
Mflv_4545|M.gilvum_PYR-GCK VTRTPAMERAGLN---FDAPGIIVNDPA---DVAREGLRHIADGPVFIAG
MSMEG_2895|M.smegmatis_MC2_155 VTRTPAMERVGLN---FDVPGMIVNDPA---DVAAEGLANLANGPVHIAG
TH_2749|M.thermoresistible__bu VTRTPAMERAGLN---FDVPGLRVADPA---DVAREGLERLPHGPVHVAG
Mvan_2633|M.vanbaalenii_PYR-1 VTRTPAMERVGLN---FDVPGLRVSEPA---EVAAEGLRQLPHGPVHVVN
MAV_5238|M.avium_104 KTDTPALRALEYSRGQIASPDQAPSDAAAVSDVIAEAFENLGNGPTLMVG
MLBr_00429|M.leprae_Br4923 PVRTELPDHDEASLVEKLVPDFLWISTE---HTARLSLDALERNKMRVVP
MAB_1537c|M.abscessus_ATCC_199 PVRTVEPDPAEASIVDKVVPDFLWINGE---YTARVSLNALERNKMRVVP
MUL_0124|M.ulcerans_Agy99 YVHTEF--HARAGIDMTKLPSFMWLDVD---DVIQESLADIADGKVIGIP
Mb3199|M.bovis_AF2122/97 LVDTDMGRFADAP----------KSDPA---DVVRQVLDGIEAGKEDVLA
Rv3174|M.tuberculosis_H37Rv LVDTDMGRFADAP----------KSDPA---DVVRQVLDGIEAGKEDVLA
. * . . : : .
MMAR_3509|M.marinum_M DNAAHVHRGSG-ADRAAIVLRAHRAMQALIGSPPPPPKGDRA
Mflv_4545|M.gilvum_PYR-GCK GNAERAARSSA-PDRAAVVLGSHEMIKRLRGMRP--------
MSMEG_2895|M.smegmatis_MC2_155 GNAAIAAANNA-PDRAKVVLQAHERMRRLINRGA--------
TH_2749|M.thermoresistible__bu GNAEDVARRND-PDRAKVVLGAHRFVQKLIGQA---------
Mvan_2633|M.vanbaalenii_PYR-1 GNEDDVARRND-PDRARVVLGAHRFMQKLIGGRGHR------
MAV_5238|M.avium_104 DTMRAAAQLLASLSRNQAVELFAQAAAAAMGPDD--------
MLBr_00429|M.leprae_Br4923 GLTSKAMSVASRYAPRAIVASIVGNFYKKLGGG---------
MAB_1537c|M.abscessus_ATCC_199 GITSKAMSVAAGYAPRAVVAPIVGSFYKKLGD----------
MUL_0124|M.ulcerans_Agy99 GVQYKALVGAGRMIPRGLLRAVMKRVGGGRGRT---------
Mb3199|M.bovis_AF2122/97 DEMSRQV-------RASLNVPARERIARLMGN----------
Rv3174|M.tuberculosis_H37Rv DEMSRQV-------RASLNVPARERIARLMGN----------
. .