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TSAARADRNAPRRVFRDRHEAGQVLADLLTAYRDRPDVIVLGLARGGIPVAWEVAAALHAPLDAFIVRKL GAPGHEEFAVGALASGGRVVVNDDVVRGLRITPQQLRDTAEREARELVRREAAYRAGRPPLDVAGKTVVL VDDGLATGASMFAAVQAIRDAEPAHIVIAVPAAPESSCREFAGLVDDVVCASMPTPFLAVGESFWDFRQV TDEEVRNLLATPTTGIPALRPAVPTPAEVIRNVAIDAHGGVPPREALEAVIGDARIVLIGESSHGTHEFY EARAEITKWLIEQKGFCAVAAEADWPDAYRVNRYVHGLGEDQSAEQALRGFERFPAWMWRNTVVRDFVDW LRERNQRCASNGQRQAGFYGLDLYSLHRSMQEVVAFLDRVDPAAAARARARYACFDHTAADDGQAYGYAA AFGAGPSCERQAIEQLVDTQRNALDYARRDGLIAEDEAFYAQQNAQTVRNAEVYYRAMFSGRVTSWNLRD QHMAETLAALQAHLDRHREAAPARIVVWAHNSHVGDARATEVWADGQLTLGQLVRQRYGDDSRLIGLCTY SGTVTAASEWGGIAERKVVRPALHASVEELFHDTGKDAFLVSAATSPEAADPLSGVRLGRAIGVIYLPAT ERQSHYFHVRPADQFDAMIHIDKTRALEPLETTSLWIAGETPETYPSGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3483 | - | - | 100% (680) | hypothetical protein MMAR_3483 |
| M. marinum M | MMAR_2069 | - | 1e-42 | 43.96% (207) | hypothetical protein MMAR_2069 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2056c | - | 0.0 | 82.42% (586) | hypothetical protein Mb2056c |
| M. gilvum PYR-GCK | Mflv_4988 | - | 0.0 | 77.24% (681) | erythromycin esterase |
| M. tuberculosis H37Rv | Rv2030c | - | 0.0 | 81.91% (680) | hypothetical protein Rv2030c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4659 | - | 3e-57 | 52.86% (210) | hypothetical protein MAB_4659 |
| M. avium 104 | MAV_2347 | - | 7e-69 | 61.86% (215) | phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4215 | - | 4e-69 | 62.26% (212) | phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_3117 | - | 4e-46 | 47.62% (210) | PUTATIVE Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) |
| M. ulcerans Agy99 | MUL_3276 | - | 7e-43 | 43.96% (207) | hypothetical protein MUL_3276 |
| M. vanbaalenii PYR-1 | Mvan_1393 | - | 0.0 | 76.65% (681) | erythromycin esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2056c|M.bovis_AF2122/97 MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGG
Rv2030c|M.tuberculosis_H37Rv MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGG
MMAR_3483|M.marinum_M --MTSAARADRNAPRRVFRDRHEAGQVLADLLTAYRDRPDVIVLGLARGG
Mflv_4988|M.gilvum_PYR-GCK --MTTARRAASDQPRRVFRDRREAGQALAGLLGGYRGRENVVVLGLARGG
Mvan_1393|M.vanbaalenii_PYR-1 --MATARRTISDQPRRVFRDRREAGRVLAGLLGGYRGREGLVVLGLARGG
MAV_2347|M.avium_104 --------------MRSFRDRREAGRALAGELMGYRNRGDVLVFGLARGG
MSMEG_4215|M.smegmatis_MC2_155 ----MSAWSVRHDAIRTFQDRREAGRVLAQRLSSYRDDPDVLVLGLARGG
MAB_4659|M.abscessus_ATCC_1997 ----------MSDTHRMFSDRQDAGRVLAGMLAPRKLR-SIVVLALPRGG
TH_3117|M.thermoresistible__bu ----------MRADTRPFDDRVDAGRRPAERLASFRGR-DVVVLGLPRGG
MUL_3276|M.ulcerans_Agy99 --------------MRQFSDRIDAGRKLGRRLEFLRGQ-DIVVLGLPRGG
* * ** :**: . * : .::*:.*.***
Mb2056c|M.bovis_AF2122/97 LPVAWEVAAALHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVR
Rv2030c|M.tuberculosis_H37Rv LPVAWEVAAALHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVR
MMAR_3483|M.marinum_M IPVAWEVAAALHAPLDAFIVRKLGAPGHEEFAVGALASGGRVVVNDDVVR
Mflv_4988|M.gilvum_PYR-GCK IPVAWEVAAALGAPLDAFIVRKLGAPGHDEFAMGALASGGRVVVNDDVVR
Mvan_1393|M.vanbaalenii_PYR-1 IPVAWEVAAALGAPLDAFIVRKLGAPGHEEFAMGALASGGRVVVNDDVVR
MAV_2347|M.avium_104 LPVAWEIAAALHAPLDVFLVRKLGVPNWSELAMGALASGGGVVMNDDVVS
MSMEG_4215|M.smegmatis_MC2_155 VPVAWEVAAHLRAPLDVFLVRKLGVPQWQELAMGAVASGGGVVLNEKLMD
MAB_4659|M.abscessus_ATCC_1997 IPVGREIATALNAPLAVLVVRKLGVPGHEEYAMGAIASGGEVILDDDIVR
TH_3117|M.thermoresistible__bu VPVAFAVARALRAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVVNDAVVR
MUL_3276|M.ulcerans_Agy99 VPVAFEVAKALHAPLDVLLVRKLGVPLHSELAFGAIGEGGVQVINSAVVH
:**. :* * *** .::*****.* * *.**:...* :::. ::
Mb2056c|M.bovis_AF2122/97 GLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLAT
Rv2030c|M.tuberculosis_H37Rv GLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLAT
MMAR_3483|M.marinum_M GLRITPQQLRDTAEREARELVRREAAYRAGRPPLDVAGKTVVLVDDGLAT
Mflv_4988|M.gilvum_PYR-GCK ALRVSPQQPRDVAEREGRELLRREAAYRAGRPPLELAGKTVIVVDDGLAT
Mvan_1393|M.vanbaalenii_PYR-1 ALRVSPQQLRDVAEREGRELHRREAAYRGGRPPLELAGKTVILVDDGLAT
MAV_2347|M.avium_104 SLRITDEQVRAVIDSETAELARREHAYRGDRPMADLRDKVVILVDDGIAT
MSMEG_4215|M.smegmatis_MC2_155 RLGISDDDMAETLRRETIELERREQAYRGDREPLQVAGRTVILVDDGIAT
MAB_4659|M.abscessus_ATCC_1997 SMGVTPIQLDEVTDRERRELARRERIYLAHR-SVEIRDKTVILVDDGIAT
TH_3117|M.thermoresistible__bu RTRLTRADMAAVERRERAELQRRSERYRGGRSRIPLSGRVAVIVDDGVAT
MUL_3276|M.ulcerans_Agy99 EAGLGEQEMAAVETAQWAELQRRVQRYRGDRHPIPLRGRIAVIVDDGVAT
: : : ** ** * . * : .: .::****:**
Mb2056c|M.bovis_AF2122/97 GASMFAAVQALR----DAQPAQIVIAVPAAPESTCREFAGLVDDVVCATM
Rv2030c|M.tuberculosis_H37Rv GASMFAAVQALR----DAQPAQIVIAVPAAPESTCREFAGLVDDVVCATM
MMAR_3483|M.marinum_M GASMFAAVQAIR----DAEPAHIVIAVPAAPESSCREFAGLVDDVVCASM
Mflv_4988|M.gilvum_PYR-GCK GSSMFAAVQALQ----EMDPAEVVIAVPAAPESTCREFAAIVDDVVCASM
Mvan_1393|M.vanbaalenii_PYR-1 GSSMMAAVQALR----ELDPAEIVVAVPAAPESTVREFGGLVDDVVCASM
MAV_2347|M.avium_104 GASMLAAVRALRSGPTGATPRSIVVAVPVGPESACRELGREADEVVCLST
MSMEG_4215|M.smegmatis_MC2_155 GASMMAAVRAVR------GARRVVVAVPVGPPGVCRELAAEADDVVCASM
MAB_4659|M.abscessus_ATCC_1997 GATMRVALLTVK----RASPARVVAAVPVAPRSAVGRFGSLVDDFVVATC
TH_3117|M.thermoresistible__bu GATAKAACQVVR----AEGAARVVLAVPVGPPDVAERFAGYADEVVCLQT
MUL_3276|M.ulcerans_Agy99 GATAAAACQVAR----AQGASRVILAVPIGATDTAPRFTEYADEVVCLET
*:: .* . : . :: *** .. . .: .*:.*
Mb2056c|M.bovis_AF2122/97 PTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRP-AASTAADVLRR
Rv2030c|M.tuberculosis_H37Rv PTPFLAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRP-AASTAADVLRR
MMAR_3483|M.marinum_M PTPFLAVGESFWDFRQVTDEEVRNLLATPTTGIPALRP-AVPTPAEVIRN
Mflv_4988|M.gilvum_PYR-GCK PTPFLAVGESFWDFRQVTDDEVRELLETPTVGFATARIRLAETPAEVIDR
Mvan_1393|M.vanbaalenii_PYR-1 PTPFRAVGESFWDFTQVSDDDVHELLTTPTVGIATARIRLAETPADVITR
MAV_2347|M.avium_104 PPGFEAVGQVYGDFHQVSDDEVRELLATPTG-------------------
MSMEG_4215|M.smegmatis_MC2_155 PQDFEAVGQAFADFHQVSDDEVRELLATPTTDPVR---------------
MAB_4659|M.abscessus_ATCC_1997 PSRFQAVGDAYRDFHQISDREVRELLSAPVIR------------------
TH_3117|M.thermoresistible__bu PPFFSAVGQGYRNFTQTSDDEVIALLRRARADVADTAAADIGDPPPLRDE
MUL_3276|M.ulcerans_Agy99 PTPYFAVGQGYDNFTQTSDQEVVTLLDRARSEFG---AGHQPPVPARRDD
* : ***: : :* * :* :* ** .
Mb2056c|M.bovis_AF2122/97 VAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIE
Rv2030c|M.tuberculosis_H37Rv VAIDAPGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIE
MMAR_3483|M.marinum_M VAIDAHGGVPPREALEAVIGDARIVLIGESSHGTHEFYEARAEITKWLIE
Mflv_4988|M.gilvum_PYR-GCK CAVDAPAGVPPLEALDELIGDARIVLIGESSHGTEEFYAARAEITKWLIE
Mvan_1393|M.vanbaalenii_PYR-1 CAVDAPSGVPPYEALEEVIGDARIVLIGESSHGTHEFYEARAEITKWLIE
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu EVRVDAGGVTVTGHLTVPGQPIGVVVFAHGSG------------------
MUL_3276|M.ulcerans_Agy99 GVRVLAGPASVIGRLTIPDRPTGIVVFAHGSGS-----------------
Mb2056c|M.bovis_AF2122/97 EKGFGAVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNT
Rv2030c|M.tuberculosis_H37Rv EKGFGAVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNT
MMAR_3483|M.marinum_M QKGFCAVAAEADWPDAYRVNRYVHGLGEDQSAEQALRGFERFPAWMWRNT
Mflv_4988|M.gilvum_PYR-GCK EKGFCGVAAEADWPDAYRVNRYVRGQAGDGSAEEALRGFERFPAWMWRNT
Mvan_1393|M.vanbaalenii_PYR-1 EKGFCAVAAEADWPDAYRVNRYVRGQDRDASADEALSGFERFPAWMWRNT
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------------------------------------------------
MUL_3276|M.ulcerans_Agy99 --------------------------------------------------
Mb2056c|M.bovis_AF2122/97 VVRDFVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDP
Rv2030c|M.tuberculosis_H37Rv VVRDFVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDP
MMAR_3483|M.marinum_M VVRDFVDWLRERNQRCASNGQRQAGFYGLDLYSLHRSMQEVVAFLDRVDP
Mflv_4988|M.gilvum_PYR-GCK VVRDFVAWLRACNADRRAQGRREAGFYGLDLYSLHRSMQEVIDFLDRVDP
Mvan_1393|M.vanbaalenii_PYR-1 VVRDFVDWLHARNSRCRADGRREAGFYGLDLYSLHRSMREVIGYLENIDP
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------RHSPRNRYVADVLRRAGLATLLFDLLTPDEELDRANVFDIGL
MUL_3276|M.ulcerans_Agy99 -------SRHSPRNRYVAEVLNQAGLATLLLDLLTPEEEHNRANVFDIGL
Mb2056c|M.bovis_AF2122/97 RAAARARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRN
Rv2030c|M.tuberculosis_H37Rv RAAARARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRN
MMAR_3483|M.marinum_M AAAARARARYACFDHTAADDGQAYGYAAAFGAGPSCERQAIEQLVDTQRN
Mflv_4988|M.gilvum_PYR-GCK DAAQRARERYSCFDHSSGDDGQAYGFAAAFGAGLSCEHQAVEQLVEMHRS
Mvan_1393|M.vanbaalenii_PYR-1 AAAQRAANRYACFDHTSADDGQAYGFAAAFGAGLSCEQQAVEQLVELHRN
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu LAERLVGVTQWLAAQPETAALPVGYFGASTGAG-----------------
MUL_3276|M.ulcerans_Agy99 LARRLVDVTGWLAAQPDTTALPVGFFGASTGGG-----------------
Mb2056c|M.bovis_AF2122/97 ALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRAMFSGRVTSWNLRDQH
Rv2030c|M.tuberculosis_H37Rv ALAYARQDGLLAEDELFYAQQNAQTVRDAEVYYRAMFSGRVTSWNLRDQH
MMAR_3483|M.marinum_M ALDYARRDGLIAEDEAFYAQQNAQTVRNAEVYYRAMFSGRVTSWNLRDQH
Mflv_4988|M.gilvum_PYR-GCK AVEYARRDGLLAEDELFYAQQNAQTVRDAEVYYRSMFGGRVTSWNLRDRH
Mvan_1393|M.vanbaalenii_PYR-1 AMEYARRDGFVAEDELFYAQQNAQTVRDAEVYYRSMFAGRVSSWNLRDRH
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------AALVAAADPRVQVAAVVSRGGRPDLAGQALGKVRAPTLLIVG
MUL_3276|M.ulcerans_Agy99 --------AALVAAAHPGVKVQAVVSRGGRPDLAGDALREVHAPTLPIVG
Mb2056c|M.bovis_AF2122/97 MAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQ
Rv2030c|M.tuberculosis_H37Rv MAQTLGSLLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQ
MMAR_3483|M.marinum_M MAETLAALQAHLDRHREAAPARIVVWAHNSHVGDARATEVWADGQLTLGQ
Mflv_4988|M.gilvum_PYR-GCK MAETLEALLRHLDRQGGSEPARIVVWAHNSHVGDARATEVGADGQLTLGQ
Mvan_1393|M.vanbaalenii_PYR-1 MAQTMEALLAHLDRHSGSEPARIVVWAHNSHVGDARATEVGADGQLTLGQ
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu GRDRFVLELNHQARAAIPAVCEIAVIPGATHLFEE------PGALDQVAE
MUL_3276|M.ulcerans_Agy99 GRDEAVLELNRQAQAAIPAPCELVVVPGATHLFEE------PGALEQVAT
Mb2056c|M.bovis_AF2122/97 IVRERYGDESRSIGFSTYTGTVTAASEWGGIAQRKAVRPALH--------
Rv2030c|M.tuberculosis_H37Rv IVRERYGDESRSIGFSTYTGTVTAASEWGGIAQRKAVRPALHGSVEELFH
MMAR_3483|M.marinum_M LVRQRYGDDSRLIGLCTYSGTVTAASEWGGIAERKVVRPALHASVEELFH
Mflv_4988|M.gilvum_PYR-GCK LAREKFGDHVRLIGYTTYTGTVTAASEWGGLAERKAVRPALNGSVEELFH
Mvan_1393|M.vanbaalenii_PYR-1 LAREKFGEDARLIGFTTYSGTVTAASTWGGVAERKAVRPGLNGSVEELFH
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu LARDWFTDHLSRTGASTRP-------------------------------
MUL_3276|M.ulcerans_Agy99 LARDWFLGHLRHH-------------------------------------
Mb2056c|M.bovis_AF2122/97 -----------AVSRSSSTRLQTVSWCQRG--------------------
Rv2030c|M.tuberculosis_H37Rv QT-ADSFLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLHVRPA
MMAR_3483|M.marinum_M DTGKDAFLVSAATSPEAADPLSGVRLGRAIGVIYLPATERQSHYFHVRPA
Mflv_4988|M.gilvum_PYR-GCK EVDRPAFLVSPLISHAAAEPLDAVRLGRAIGVIYLPATERQSHYYHVRPS
Mvan_1393|M.vanbaalenii_PYR-1 EVERPEFLVSPMISKAAAEPLDAVRLARAIGVIYLPATERQSHYYHVRPG
MAV_2347|M.avium_104 --------------------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4659|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3117|M.thermoresistible__bu --------------------------------------------------
MUL_3276|M.ulcerans_Agy99 --------------------------------------------------
Mb2056c|M.bovis_AF2122/97 -------------------------------------
Rv2030c|M.tuberculosis_H37Rv DQFDAMIHIDQTRALEPLEVTSRWIAGENPETYPTGL
MMAR_3483|M.marinum_M DQFDAMIHIDKTRALEPLETTSLWIAGETPETYPSGL
Mflv_4988|M.gilvum_PYR-GCK EQFDGIIHIDRTTALEPLEVTSTWAAGETPETYPTGL
Mvan_1393|M.vanbaalenii_PYR-1 DQYDALIHIDTTTALEPLETTSVWVAGETPETYPTGL
MAV_2347|M.avium_104 -------------------------------------
MSMEG_4215|M.smegmatis_MC2_155 -------------------------------------
MAB_4659|M.abscessus_ATCC_1997 -------------------------------------
TH_3117|M.thermoresistible__bu -------------------------------------
MUL_3276|M.ulcerans_Agy99 -------------------------------------