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MTTARPAKTRNEGQWALGQLDPLNDTEQIKHDDGPLNVRDRILNKYAKEGFDSIEKTDLRLRFKWMGLYT QREQGYDGSWTGDENIDKLEAKYFMMRVRSDGKPMSAQTVRVLGQISSEFGRDTADIGDRENVQFHWLRI EDVPEIWRRLESVGLSSIEACGDCPRGIHGSPLAGDSLDEVLDPSPAIDEIIRRFLGNPDYANLPRKYKS AISGLQDVSHETHDVAFVGVNHPEHGPGMDLWVGGGLSTNPMMAQRVGVWVPLDEVPDVWEAVTQVFRDY GYRRLRAKARIKFLVKDWGVEKFREVMETEYLKRKLIDGPAPEPIKHPIDHVGVQKIKNGLNAVGVAAIA GRVTGTTLQAVADLMERVGSDRARFSPFQKLIILDVPDDKVDELVTGLDKLGLPSKPSGWRKNTMACTGI EFCKLSFAETRVRAQSLVPELEERMADVESKIDVPITLHINGCPNSCARIQVADIGFKGQWIDDGEGNSV EGFQVHLGGGLGEQSGFGRKLRQHKVTSDELGDYIDRVTRKFLDQREEGERFANWALRADEADLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3416 | nirA | - | 100% (555) | ferredoxin-dependent nitrite/sulphite reductase NirA |
| M. marinum M | MMAR_3710 | nirA_2 | 0.0 | 75.50% (555) | ferredoxin-dependent nitrite reductase, NirA_2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2412 | nirA | 0.0 | 76.22% (555) | ferredoxin-dependant nitrite reductase NIRA |
| M. gilvum PYR-GCK | Mflv_2686 | - | 0.0 | 73.24% (553) | ferredoxin--nitrite reductase |
| M. tuberculosis H37Rv | Rv2391 | nirA | 0.0 | 76.22% (555) | ferredoxin-dependent nitrite reductase NIRA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1662c | - | 0.0 | 71.74% (552) | sulfite reductase |
| M. avium 104 | MAV_2154 | - | 0.0 | 83.60% (555) | sulfite reductase |
| M. smegmatis MC2 155 | MSMEG_4527 | - | 0.0 | 74.82% (552) | ferredoxin sulfite reductase |
| M. thermoresistible (build 8) | TH_1443 | nirA | 0.0 | 77.72% (552) | PROBABLE FERREDOXIN-DEPENDENT NITRITE REDUCTASE NIRA |
| M. ulcerans Agy99 | MUL_3652 | nirA_2 | 0.0 | 74.95% (555) | ferredoxin-dependent nitrite reductase, NirA_2 |
| M. vanbaalenii PYR-1 | Mvan_3857 | - | 0.0 | 72.19% (561) | ferredoxin--nitrite reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2412|M.bovis_AF2122/97 MSAKENPQ------MTTARP-AKARNEGQWALGHREPLNANEELKKAGNP
Rv2391|M.tuberculosis_H37Rv MSAKENPQ------MTTARP-AKARNEGQWALGHREPLNANEELKKAGNP
MUL_3652|M.ulcerans_Agy99 --------------MTTARP-AKPRNEGQWALGNREPFNANEELKKAGNP
Mflv_2686|M.gilvum_PYR-GCK MTTAKT---------PPAKPAKRPRGEGQWALGYREPLNPNEQSKKDDNP
Mvan_3857|M.vanbaalenii_PYR-1 MTTAQD---------KPVKPVKRPRGEGQWALGYREPLNPNERSKRDDNP
MSMEG_4527|M.smegmatis_MC2_155 MTSSEAPAKTAEKPAPKTRPAKRPRGEGQWALGYREPLNANEQAKKDDNP
MAB_1662c|M.abscessus_ATCC_199 MTTSET---------RPARP-KQQRSEGQWALGELEPLNSNEQVKKDDHP
TH_1443|M.thermoresistible__bu MTEAKT--------QAKPRPARKPRSEGQWALGERDPLNPNEQFKQEDDA
MMAR_3416|M.marinum_M --------------MTTARP-AKTRNEGQWALGQLDPLNDTEQIKHDDGP
MAV_2154|M.avium_104 --------------MTAARP-VKTRNEGQWALGDREPLNDTEKIKLADGP
:* : *.******* :*:* .*. * . .
Mb2412|M.bovis_AF2122/97 LDVRERIENIYAKQGFDSIDKTDLRGRFRWWGLYTQREQGYDGTWTGDDN
Rv2391|M.tuberculosis_H37Rv LDVRERIENIYAKQGFDSIDKTDLRGRFRWWGLYTQREQGYDGTWTGDDN
MUL_3652|M.ulcerans_Agy99 LDVRERIENIYAKAGFDSIDKSDLRGLFRWWGLYTQREQGYDGSWTGDEN
Mflv_2686|M.gilvum_PYR-GCK LNVRERIENIYAKNGFESIDKGDLRGRFRWWGLYTQRKPGYDGTWTGDEN
Mvan_3857|M.vanbaalenii_PYR-1 LNVRARIENIYAQGGFDSIDKGDLRGRFRWWGLYTQRKPGYDGTWTGDEN
MSMEG_4527|M.smegmatis_MC2_155 LNVRARIENIYAKNGFESIDKGDLRGRFRWWGLYTQRKPGYDGTWTGDEN
MAB_1662c|M.abscessus_ATCC_199 LNVRERIETIYSKQGFDSIDKADLRGRFRWWGLYTQRKQGYDGTWTGDDN
TH_1443|M.thermoresistible__bu LNVRDRIINTYAKNGFDSIDKTDLRGRFRWMGLYTQREQGYDGTWTGDEN
MMAR_3416|M.marinum_M LNVRDRILNKYAKEGFDSIEKTDLRLRFKWMGLYTQREQGYDGSWTGDEN
MAV_2154|M.avium_104 LNVRERIINVYAKQGFGSIDKSDLRGRFRWMGLYTQREQGYDGSWTGDDN
*:** ** . *:: ** **:* *** *:* ******: ****:****:*
Mb2412|M.bovis_AF2122/97 IDKLEAKYFMMRVRCDGGALSAAALRTLGQISTEFARDTADISDRQNVQY
Rv2391|M.tuberculosis_H37Rv IDKLEAKYFMMRVRCDGGALSAAALRTLGQISTEFARDTADISDRQNVQY
MUL_3652|M.ulcerans_Agy99 IDKLEAKYFMLRVRCDGGALSTAALRTLGAISTEFARDTADISDRENLQY
Mflv_2686|M.gilvum_PYR-GCK TDMLEDEYFMLRVRSDGGALTAAALRTLGTISTEFARDTADISDRQNVQY
Mvan_3857|M.vanbaalenii_PYR-1 TDMLEDSYFMLRVRSDGGALSAEALRTLGGISTEFARDTADLSDRQNVQY
MSMEG_4527|M.smegmatis_MC2_155 TDMLEDEYFMLRVRCDGGALTTAALRTLGGISTEFARDTADISDRENVQY
MAB_1662c|M.abscessus_ATCC_199 TDMLEDDHFMLRVRCDGGALTTQALRTIGELSTQYARDTADISDRQNVQY
TH_1443|M.thermoresistible__bu ADLLEAKYFMMRVRCDGKALSAAALRTLGEISTEFARDTADISDRMNLQY
MMAR_3416|M.marinum_M IDKLEAKYFMMRVRSDGKPMSAQTVRVLGQISSEFGRDTADIGDRENVQF
MAV_2154|M.avium_104 TDKIEAKYFMMRVRSDGKAMSAHTMRTLGQISTEFARDTADISDRENLQL
* :* .:**:***.** .::: ::*.:* :*:::.*****:.** *:*
Mb2412|M.bovis_AF2122/97 HWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVLGSPLAGESLDEVLDPT
Rv2391|M.tuberculosis_H37Rv HWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVLGSPLAGESLDEVLDPT
MUL_3652|M.ulcerans_Agy99 HWIEVEKVPEIWRRLDEVGLHTTEACGDCPRVVLGSPLAGESLDEVLDPT
Mflv_2686|M.gilvum_PYR-GCK HWIDVKDMPEIWRRLDEVGLQTTEACGDCPRVVLGSPLAGESLDEVIDGT
Mvan_3857|M.vanbaalenii_PYR-1 HWIEVENMPEIWRRLDAVGLQTTEACGDCPRVVLGSPLAGESLDEVIDGT
MSMEG_4527|M.smegmatis_MC2_155 HWIQVENMPEIWKRLDAVGLQTTEACGDCPRVVLGSPLAGESLDEVIDGT
MAB_1662c|M.abscessus_ATCC_199 HWIRVEDMPEIWRRLDEVGLYTTQACGDCPRVILGSPLAGESLDEVLDPT
TH_1443|M.thermoresistible__bu HWIEIENVPEIWRRLDEHGLQTTEACGDCPRALLGSPLAGESLDEVLDPT
MMAR_3416|M.marinum_M HWLRIEDVPEIWRRLESVGLSSIEACGDCPRGIHGSPLAGDSLDEVLDPS
MAV_2154|M.avium_104 HWIRIEDVPEIWRRLESVGLQTTEACGDCPRGIHGSPLAGDSLDEVLDPS
**: ::.:****:**: ** : :******* : ******:*****:* :
Mb2412|M.bovis_AF2122/97 WAIEEIVRRYIGKPDFADLPRKYKTAISGLQDVAHEINDVAFIGVNHPEH
Rv2391|M.tuberculosis_H37Rv WAIEEIVRRYIGKPDFADLPRKYKTAISGLQDVAHEINDVAFIGVNHPEH
MUL_3652|M.ulcerans_Agy99 WAIDEIVRRYIGKPDFADLPRKYKTAISGLQDVVHEVNDVAFIGVNHPEH
Mflv_2686|M.gilvum_PYR-GCK PAVNEIVKRYIGKKEYSNLPRKFKTAISGLQDVVHEVNDVAFIGVNHPEH
Mvan_3857|M.vanbaalenii_PYR-1 PAVDEIVKRYIGKPEYSNLPRKFKTAISGLQDVVHEVNDVAFIGVNHPEH
MSMEG_4527|M.smegmatis_MC2_155 PAIDEIVRRYIGKPEYSNLPRKFKTAISGLQDVVHEVNDVAFIGVNHPEH
MAB_1662c|M.abscessus_ATCC_199 WAIDEITRRYIGNKEYANLPRKFKTAISGLQDVVHEINDVAFVGVVHPEH
TH_1443|M.thermoresistible__bu PALDEIVRRYIGNPEYSNLPRKYKTAISGLQDVAHEVNDVAFIGVNHPEH
MMAR_3416|M.marinum_M PAIDEIIRRFLGNPDYANLPRKYKSAISGLQDVSHETHDVAFVGVNHPEH
MAV_2154|M.avium_104 PAIEEIVRRSLNNPEYANLPRKYKTAVSGLQDVSHETHDVAFVGVDHPEH
*::** :* :.: ::::****:*:*:****** ** :****:** ****
Mb2412|M.bovis_AF2122/97 GPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAAVTSVFRDYGYRRL
Rv2391|M.tuberculosis_H37Rv GPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAAVTSVFRDYGYRRL
MUL_3652|M.ulcerans_Agy99 GPGLDLWVGGGLSTNPMLAKRVGAWVPLEEVPEVWAAVTSVFRDYGYRRL
Mflv_2686|M.gilvum_PYR-GCK GPGFDLWVGGGLSTNPMLGQRVGAWVPLDEVPDVWEGVVSVFRDYGYRRL
Mvan_3857|M.vanbaalenii_PYR-1 GPGFDLWVGGGLSTNPMLAQRVGVWVPLDEVPDVWEGVVSVFRDYGYRRL
MSMEG_4527|M.smegmatis_MC2_155 GPGFDLWVGGGLSTNPMLAQRVGVWVPLDEVPDVWEGVVSIFRDYGYRRL
MAB_1662c|M.abscessus_ATCC_199 GPGLDIWVGGGLSTNPMLAQRLGAWVPLDEVPDVWEGVVGIFRDYGYRRL
TH_1443|M.thermoresistible__bu GPGLDLWVGGGLSTNPMLAQRVGAWVPLDEVPDVWEAVTAVFRDYGYRRL
MMAR_3416|M.marinum_M GPGMDLWVGGGLSTNPMMAQRVGVWVPLDEVPDVWEAVTQVFRDYGYRRL
MAV_2154|M.avium_104 GPGLDLWVGGGLSTNPMLAQRLGVWVPLDEVPDVWEAVTQLFRDYGYRRL
***:*:***********:.:*:*.**** ***:** .*. :*********
Mb2412|M.bovis_AF2122/97 RAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKHPIDHVGVQ
Rv2391|M.tuberculosis_H37Rv RAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKHPIDHVGVQ
MUL_3652|M.ulcerans_Agy99 RSKARLKFLIKDWGIEKFREVLETEYLKRPLIDGPAPEPAKHPIDHVGVQ
Mflv_2686|M.gilvum_PYR-GCK RAKARLKFLIKDWGVEKFRQVLEEEYLKRPLIDGPAPEPVTRPIDHVGVQ
Mvan_3857|M.vanbaalenii_PYR-1 RSKARLKFLIKDWGAQKFREVLETEYLHRPLLDGPAPEPVTRPIDHVGVQ
MSMEG_4527|M.smegmatis_MC2_155 RSKARLKFLIKDWGVEKFREVLETEYLKRPLIDGPAPEPVTRPIDHVGVQ
MAB_1662c|M.abscessus_ATCC_199 RSKARLKFLVKDWGVAKFREILETEYLKRPLIDGPAPVPPTHPIDHVGVQ
TH_1443|M.thermoresistible__bu RSKARLKFLIKDWGVEKFREVLETEYLKRPLIDGPAPEPVKHPIDHVGVQ
MMAR_3416|M.marinum_M RAKARIKFLVKDWGVEKFREVMETEYLKRKLIDGPAPEPIKHPIDHVGVQ
MAV_2154|M.avium_104 RAKARLKFLVKDWGIEKFREILEQEYLNRRLIDGPAPAPVKHTIDHVGVQ
*:***:***:**** ***:::* ***:* *:***** * .:.*******
Mb2412|M.bovis_AF2122/97 RLKNGLNAVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTPYQKLVILD
Rv2391|M.tuberculosis_H37Rv RLKNGLNAVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTPYQKLVILD
MUL_3652|M.ulcerans_Agy99 RLKNGHNAVGVSPIAGRVSGTILTAVAELAERAGSDRIRFTPYQKLVILD
Mflv_2686|M.gilvum_PYR-GCK KLKNGLNAVGVAPIAGRVSGTILTKVADLAEAAGSDRIRFTPYQKLIVLD
Mvan_3857|M.vanbaalenii_PYR-1 KLKNGLNAVGVAPIAGRVSGTILTKVADLAEAAGSDRIRFTPYQKLIILD
MSMEG_4527|M.smegmatis_MC2_155 KLKNGLNAVGVAPIAGRVSGTILTKVADLAEAAGSDRIRFTPYQKLIILD
MAB_1662c|M.abscessus_ATCC_199 RLKNGLNAIGISAIAGRVSGTILSAIADLAEKAGSNRVALTPHQKLIILD
TH_1443|M.thermoresistible__bu KLKNGLNAVGIAPIAGRVSGTILQAVADLMAQAGSDRARFTPYQKLIVLD
MMAR_3416|M.marinum_M KIKNGLNAVGVAAIAGRVTGTTLQAVADLMERVGSDRARFSPFQKLIILD
MAV_2154|M.avium_104 KIKNGLNAVGVAPIAGRVSGTTLSAVADLMEQVGSDRARWTPFQKLVILD
::*** **:*::.*****:** * :*:* .**:* :*.***::**
Mb2412|M.bovis_AF2122/97 IPDALLDDLIAGLDALGLQSRPSHWRRNLMACSGIEFCKLSFAETRVRAQ
Rv2391|M.tuberculosis_H37Rv IPDALLDDLIAGLDALGLQSRPSHWRRNLMACSGIEFCKLSFAETRVRAQ
MUL_3652|M.ulcerans_Agy99 IPDDKLDETIAGLQALGLRAQPSHWRRNLMACSGIEFCKLSFAETRVRAQ
Mflv_2686|M.gilvum_PYR-GCK VPDDKLDELRAGLDALGLPSTPSHWRRNLMACTGIEFCKLSFAETRSRSQ
Mvan_3857|M.vanbaalenii_PYR-1 VADENVAKLVEQLDALGLPSTPSHWRRNLMACTGIEFCKLSFAETRSRSQ
MSMEG_4527|M.smegmatis_MC2_155 VPDDKIDELRAGLDALGLPSTPSHWRRNLMACTGIEFCKLSFAETRKRAQ
MAB_1662c|M.abscessus_ATCC_199 VSDDELPALEAGLNALGLPSRPSHWRKNLLACTGIEYCKLSFTETRVRAQ
TH_1443|M.thermoresistible__bu IADDKLDEFTAGLDRLGLQWQPSHWRRNLMACTGIEFCKLSFTETRVRAQ
MMAR_3416|M.marinum_M VPDDKVDELVTGLDKLGLPSKPSGWRKNTMACTGIEFCKLSFAETRVRAQ
MAV_2154|M.avium_104 VPDDKVDELVAGLDALGLPSRPSSWRKNTMACTGIEFCKLSFAETRVRTQ
:.* : *: *** ** **:* :**:***:*****:*** *:*
Mb2412|M.bovis_AF2122/97 HLVPELERRLEDINSQLDVPITVNINGCPNSCARIQIADIGFKGQMIDDG
Rv2391|M.tuberculosis_H37Rv HLVPELERRLEDINSQLDVPITVNINGCPNSCARIQIADIGFKGQMIDDG
MUL_3652|M.ulcerans_Agy99 SLVPELEERLDDINSTLDVPVAVNINGCPNSCARIQVADIGFKGQMVDDG
Mflv_2686|M.gilvum_PYR-GCK VLVPELEKRLEDINAQLDVPVTININGCPNSCARIQVADIGFKGQMVDDG
Mvan_3857|M.vanbaalenii_PYR-1 VLVPELEKRLDDINAQLDVPVTININGCPNSCARIQVADIGFKGQMVDDG
MSMEG_4527|M.smegmatis_MC2_155 VLVPELEKRLDDINAQLDVPITVNINGCPNSCARIQVADIGFKGQMVDDG
MAB_1662c|M.abscessus_ATCC_199 SLVPELEKRLDDLNAQIDTPVTINMNGCPNSCARSQTADIGFKGQMVDDG
TH_1443|M.thermoresistible__bu SLVPELEKRLEDINARLDVPITVNINGCPNSCARIQVADIGFKGMIVDDG
MMAR_3416|M.marinum_M SLVPELEERMADVESKIDVPITLHINGCPNSCARIQVADIGFKGQWIDDG
MAV_2154|M.avium_104 TLVPELERRLADVDAQLDAPISLHLNGCPNSCARIQVADIGFKGQWIDNG
******.*: *::: :*.*:::::********* * ******* :*:*
Mb2412|M.bovis_AF2122/97 HGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDRVVRNFVKH
Rv2391|M.tuberculosis_H37Rv HGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDRVVRNFVKH
MUL_3652|M.ulcerans_Agy99 AGGQVEGFQVHLGGSLGLDSGFGRKLRQHKVTSDELGDYIDRVVRNFVKN
Mflv_2686|M.gilvum_PYR-GCK DG-PEEGFQVHLGGSLGLDSGFGRKLRQHKVVATELGDYIERVVRNFVKQ
Mvan_3857|M.vanbaalenii_PYR-1 NG-PEEGFQVHLGGSLGLDSGFGRKLRQHKVLATELGDYIERVVRNFVKQ
MSMEG_4527|M.smegmatis_MC2_155 NG-PEEGFQVHLGGSLGLDSGFGRKLRQHKVLSSELGDYIERVVRNFVKQ
MAB_1662c|M.abscessus_ATCC_199 NGNSVEGFQVHLGGSLGLDSGFGRKLRQHKVTSTELGDYIDRVVRNFVAQ
TH_1443|M.thermoresistible__bu DG-PEEGFQVHLGGGLGLDSGFGRKLRQHRVLSSELGDYIDRVVRNFVKQ
MMAR_3416|M.marinum_M EGNSVEGFQVHLGGGLGEQSGFGRKLRQHKVTSDELGDYIDRVTRKFLDQ
MAV_2154|M.avium_104 DGTSVEGFQVHLGGGLGEQSGFGRKLRQHKVTSEELGDYIDRVTRRYLEG
* ********* ** ::*********:* : ******:**.*.::
Mb2412|M.bovis_AF2122/97 RSEGERFAQWVIRAEEDDLR
Rv2391|M.tuberculosis_H37Rv RSEGERFAQWVIRAEEDDLR
MUL_3652|M.ulcerans_Agy99 RAAGERFAQWAIRAEEDDLR
Mflv_2686|M.gilvum_PYR-GCK REQGERFATWALRADDADLR
Mvan_3857|M.vanbaalenii_PYR-1 REDGERFATWALRADEADLR
MSMEG_4527|M.smegmatis_MC2_155 REDGERFAQWAVRADEADLR
MAB_1662c|M.abscessus_ATCC_199 RTDGERFAQWAVRAEEADLR
TH_1443|M.thermoresistible__bu REDGERFATWALRADEADLR
MMAR_3416|M.marinum_M REEGERFANWALRADEADLR
MAV_2154|M.avium_104 RNDGETFASWALRADEEELR
* ** ** *.:**:: :**