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MSAKENPQMTTARPAKARNEGQWALGHREPLNANEELKKAGNPLDVRERIENIYAKQGFDSIDKTDLRGR FRWWGLYTQREQGYDGTWTGDDNIDKLEAKYFMMRVRCDGGALSAAALRTLGQISTEFARDTADISDRQN VQYHWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVLGSPLAGESLDEVLDPTWAIEEIVRRYIGKPDFA DLPRKYKTAISGLQDVAHEINDVAFIGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAA VTSVFRDYGYRRLRAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKHPIDHVGVQRLKNGLN AVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTPYQKLVILDIPDALLDDLIAGLDALGLQSRPSHWRR NLMACSGIEFCKLSFAETRVRAQHLVPELERRLEDINSQLDVPITVNINGCPNSCARIQIADIGFKGQMI DDGHGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDRVVRNFVKHRSEGERFAQWVIRAEED DLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2391 | nirA | - | 100% (563) | PROBABLE FERREDOXIN-DEPENDENT NITRITE REDUCTASE NIRA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2412 | nirA | 0.0 | 100.00% (563) | ferredoxin-dependant nitrite reductase NIRA |
| M. gilvum PYR-GCK | Mflv_2686 | - | 0.0 | 81.92% (553) | ferredoxin--nitrite reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1662c | - | 0.0 | 78.44% (552) | sulfite reductase |
| M. marinum M | MMAR_3710 | nirA_2 | 0.0 | 90.81% (555) | ferredoxin-dependent nitrite reductase, NirA_2 |
| M. avium 104 | MAV_1787 | - | 0.0 | 87.57% (555) | sulfite reductase |
| M. smegmatis MC2 155 | MSMEG_4527 | - | 0.0 | 81.05% (570) | ferredoxin sulfite reductase |
| M. thermoresistible (build 8) | TH_1443 | nirA | 0.0 | 83.70% (552) | PROBABLE FERREDOXIN-DEPENDENT NITRITE REDUCTASE NIRA |
| M. ulcerans Agy99 | MUL_3652 | nirA_2 | 0.0 | 90.45% (555) | ferredoxin-dependent nitrite reductase, NirA_2 |
| M. vanbaalenii PYR-1 | Mvan_3857 | - | 0.0 | 79.89% (562) | ferredoxin--nitrite reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2686|M.gilvum_PYR-GCK --------MTTAKT---------PPAKPAKRPRGEGQWALGYREPLNPNE
Mvan_3857|M.vanbaalenii_PYR-1 --------MTTAQD---------KPVKPVKRPRGEGQWALGYREPLNPNE
MSMEG_4527|M.smegmatis_MC2_155 --------MTSSEAPAKTAEKPAPKTRPAKRPRGEGQWALGYREPLNANE
Rv2391|M.tuberculosis_H37Rv ------MSAKENPQ--------MTTARPAK-ARNEGQWALGHREPLNANE
Mb2412|M.bovis_AF2122/97 ------MSAKENPQ--------MTTARPAK-ARNEGQWALGHREPLNANE
MMAR_3710|M.marinum_M ----------------------MTTARPAK-PRNEGQWALGNREPLNANE
MUL_3652|M.ulcerans_Agy99 ----------------------MTTARPAK-PRNEGQWALGNREPFNANE
MAV_1787|M.avium_104 MLAALAIFFRGERP--------MTTARPAK-ARNEGQWALGNREPLNPNE
TH_1443|M.thermoresistible__bu --------MTEAKT--------QAKPRPARKPRSEGQWALGERDPLNPNE
MAB_1662c|M.abscessus_ATCC_199 --------MTTSET---------RPARPKQ-QRSEGQWALGELEPLNSNE
:* : *.******* :*:*.**
Mflv_2686|M.gilvum_PYR-GCK QSKKDDNPLNVRERIENIYAKNGFESIDKGDLRGRFRWWGLYTQRKPGYD
Mvan_3857|M.vanbaalenii_PYR-1 RSKRDDNPLNVRARIENIYAQGGFDSIDKGDLRGRFRWWGLYTQRKPGYD
MSMEG_4527|M.smegmatis_MC2_155 QAKKDDNPLNVRARIENIYAKNGFESIDKGDLRGRFRWWGLYTQRKPGYD
Rv2391|M.tuberculosis_H37Rv ELKKAGNPLDVRERIENIYAKQGFDSIDKTDLRGRFRWWGLYTQREQGYD
Mb2412|M.bovis_AF2122/97 ELKKAGNPLDVRERIENIYAKQGFDSIDKTDLRGRFRWWGLYTQREQGYD
MMAR_3710|M.marinum_M ELKKAGNPLDVRERIENIYAKAGFDSIDKSDLRGLFRWWGLYTQREQGYD
MUL_3652|M.ulcerans_Agy99 ELKKAGNPLDVRERIENIYAKAGFDSIDKSDLRGLFRWWGLYTQREQGYD
MAV_1787|M.avium_104 EMKQAGAPLAVRERIETIYAKNGFDSIDKSDLRGRFRWWGLYTQREQGYD
TH_1443|M.thermoresistible__bu QFKQEDDALNVRDRIINTYAKNGFDSIDKTDLRGRFRWMGLYTQREQGYD
MAB_1662c|M.abscessus_ATCC_199 QVKKDDHPLNVRERIETIYSKQGFDSIDKADLRGRFRWWGLYTQRKQGYD
. *: . .* ** ** . *:: **:**** **** *** ******: ***
Mflv_2686|M.gilvum_PYR-GCK GTWTGDENTDMLEDEYFMLRVRSDGGALTAAALRTLGTISTEFARDTADI
Mvan_3857|M.vanbaalenii_PYR-1 GTWTGDENTDMLEDSYFMLRVRSDGGALSAEALRTLGGISTEFARDTADL
MSMEG_4527|M.smegmatis_MC2_155 GTWTGDENTDMLEDEYFMLRVRCDGGALTTAALRTLGGISTEFARDTADI
Rv2391|M.tuberculosis_H37Rv GTWTGDDNIDKLEAKYFMMRVRCDGGALSAAALRTLGQISTEFARDTADI
Mb2412|M.bovis_AF2122/97 GTWTGDDNIDKLEAKYFMMRVRCDGGALSAAALRTLGQISTEFARDTADI
MMAR_3710|M.marinum_M GSWTGDENIDKLEAKYFMLRVRCDGGALSAAALRTLGAISTEFARDTADI
MUL_3652|M.ulcerans_Agy99 GSWTGDENIDKLEAKYFMLRVRCDGGALSTAALRTLGAISTEFARDTADI
MAV_1787|M.avium_104 GSWTGDENIEKLEARYFMMRVRCDGGAISAAALRTLGQISVDFARDTADI
TH_1443|M.thermoresistible__bu GTWTGDENADLLEAKYFMMRVRCDGKALSAAALRTLGEISTEFARDTADI
MAB_1662c|M.abscessus_ATCC_199 GTWTGDDNTDMLEDDHFMLRVRCDGGALTTQALRTIGELSTQYARDTADI
*:****:* : ** :**:***.** *::: ****:* :*.::******:
Mflv_2686|M.gilvum_PYR-GCK SDRQNVQYHWIDVKDMPEIWRRLDEVGLQTTEACGDCPRVVLGSPLAGES
Mvan_3857|M.vanbaalenii_PYR-1 SDRQNVQYHWIEVENMPEIWRRLDAVGLQTTEACGDCPRVVLGSPLAGES
MSMEG_4527|M.smegmatis_MC2_155 SDRENVQYHWIQVENMPEIWKRLDAVGLQTTEACGDCPRVVLGSPLAGES
Rv2391|M.tuberculosis_H37Rv SDRQNVQYHWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVLGSPLAGES
Mb2412|M.bovis_AF2122/97 SDRQNVQYHWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVLGSPLAGES
MMAR_3710|M.marinum_M SDRENLQYHWIEVEKVPEIWRRLDEVGLHTTEACGDCPRVVLGSPLAGES
MUL_3652|M.ulcerans_Agy99 SDRENLQYHWIEVEKVPEIWRRLDEVGLHTTEACGDCPRVVLGSPLAGES
MAV_1787|M.avium_104 TDRENIQYHWIEVENVPEIWRRLDAVGLRTTEACGDCPRVILGSPLAGES
TH_1443|M.thermoresistible__bu SDRMNLQYHWIEIENVPEIWRRLDEHGLQTTEACGDCPRALLGSPLAGES
MAB_1662c|M.abscessus_ATCC_199 SDRQNVQYHWIRVEDMPEIWRRLDEVGLYTTQACGDCPRVILGSPLAGES
:** *:***** ::.:****:*** ** **:*******.:*********
Mflv_2686|M.gilvum_PYR-GCK LDEVIDGTPAVNEIVKRYIGKKEYSNLPRKFKTAISGLQDVVHEVNDVAF
Mvan_3857|M.vanbaalenii_PYR-1 LDEVIDGTPAVDEIVKRYIGKPEYSNLPRKFKTAISGLQDVVHEVNDVAF
MSMEG_4527|M.smegmatis_MC2_155 LDEVIDGTPAIDEIVRRYIGKPEYSNLPRKFKTAISGLQDVVHEVNDVAF
Rv2391|M.tuberculosis_H37Rv LDEVLDPTWAIEEIVRRYIGKPDFADLPRKYKTAISGLQDVAHEINDVAF
Mb2412|M.bovis_AF2122/97 LDEVLDPTWAIEEIVRRYIGKPDFADLPRKYKTAISGLQDVAHEINDVAF
MMAR_3710|M.marinum_M LDEVLDPTWAIDEIVRRYIGKPDFADLPRKYKTAISGLQDVVHEVNDVAF
MUL_3652|M.ulcerans_Agy99 LDEVLDPTWAIDEIVRRYIGKPDFADLPRKYKTAISGLQDVVHEVNDVAF
MAV_1787|M.avium_104 LEEVIDPSWAIAEIARRYIGQPEFADLPRKYKTAISGLQDVAHEVNDVAF
TH_1443|M.thermoresistible__bu LDEVLDPTPALDEIVRRYIGNPEYSNLPRKYKTAISGLQDVAHEVNDVAF
MAB_1662c|M.abscessus_ATCC_199 LDEVLDPTWAIDEITRRYIGNKEYANLPRKFKTAISGLQDVVHEINDVAF
*:**:* : *: **.:****: ::::****:**********.**:*****
Mflv_2686|M.gilvum_PYR-GCK IGVNHPEHGPGFDLWVGGGLSTNPMLGQRVGAWVPLDEVPDVWEGVVSVF
Mvan_3857|M.vanbaalenii_PYR-1 IGVNHPEHGPGFDLWVGGGLSTNPMLAQRVGVWVPLDEVPDVWEGVVSVF
MSMEG_4527|M.smegmatis_MC2_155 IGVNHPEHGPGFDLWVGGGLSTNPMLAQRVGVWVPLDEVPDVWEGVVSIF
Rv2391|M.tuberculosis_H37Rv IGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAAVTSVF
Mb2412|M.bovis_AF2122/97 IGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAAVTSVF
MMAR_3710|M.marinum_M IGVNHPEHGPGLDLWVGGGLSTNPMLAKRVGAWVPLEEVPEVWAAVTSVF
MUL_3652|M.ulcerans_Agy99 IGVNHPEHGPGLDLWVGGGLSTNPMLAKRVGAWVPLEEVPEVWAAVTSVF
MAV_1787|M.avium_104 IGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLHEVPEVWAAVTSVF
TH_1443|M.thermoresistible__bu IGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLDEVPDVWEAVTAVF
MAB_1662c|M.abscessus_ATCC_199 VGVVHPEHGPGLDIWVGGGLSTNPMLAQRLGAWVPLDEVPDVWEGVVGIF
:** *******:*:************.:*:*.**** ***:** .*..:*
Mflv_2686|M.gilvum_PYR-GCK RDYGYRRLRAKARLKFLIKDWGVEKFRQVLEEEYLKRPLIDGPAPEPVTR
Mvan_3857|M.vanbaalenii_PYR-1 RDYGYRRLRSKARLKFLIKDWGAQKFREVLETEYLHRPLLDGPAPEPVTR
MSMEG_4527|M.smegmatis_MC2_155 RDYGYRRLRSKARLKFLIKDWGVEKFREVLETEYLKRPLIDGPAPEPVTR
Rv2391|M.tuberculosis_H37Rv RDYGYRRLRAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKH
Mb2412|M.bovis_AF2122/97 RDYGYRRLRAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKH
MMAR_3710|M.marinum_M RDYGYRRLRSKARLKFLIKDWGIEKFREVLETEYLKRPLIDGPAPEPAKH
MUL_3652|M.ulcerans_Agy99 RDYGYRRLRSKARLKFLIKDWGIEKFREVLETEYLKRPLIDGPAPEPAKH
MAV_1787|M.avium_104 RDYGYRRLRSKARLKFLVKDWGIEKFREVLETEYLKRPLIDGPAPEPVAH
TH_1443|M.thermoresistible__bu RDYGYRRLRSKARLKFLIKDWGVEKFREVLETEYLKRPLIDGPAPEPVKH
MAB_1662c|M.abscessus_ATCC_199 RDYGYRRLRSKARLKFLVKDWGVAKFREILETEYLKRPLIDGPAPVPPTH
*********:*******:**** ***::** ***:***:***** * :
Mflv_2686|M.gilvum_PYR-GCK PIDHVGVQKLKNGLNAVGVAPIAGRVSGTILTKVADLAEAAGSDRIRFTP
Mvan_3857|M.vanbaalenii_PYR-1 PIDHVGVQKLKNGLNAVGVAPIAGRVSGTILTKVADLAEAAGSDRIRFTP
MSMEG_4527|M.smegmatis_MC2_155 PIDHVGVQKLKNGLNAVGVAPIAGRVSGTILTKVADLAEAAGSDRIRFTP
Rv2391|M.tuberculosis_H37Rv PIDHVGVQRLKNGLNAVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTP
Mb2412|M.bovis_AF2122/97 PIDHVGVQRLKNGLNAVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTP
MMAR_3710|M.marinum_M PIDHVGVQRLKNGHNAVGVSPIAGRVSGTILTAVAELAERAGSDRIRFTP
MUL_3652|M.ulcerans_Agy99 PIDHVGVQRLKNGHNAVGVSPIAGRVSGTILTAVAELAERAGSDRIRFTP
MAV_1787|M.avium_104 PIDHVGVQRLKNGLNAVGVAPIAGRVSGTILLAVADLAQQAGCDRIRFTP
TH_1443|M.thermoresistible__bu PIDHVGVQKLKNGLNAVGIAPIAGRVSGTILQAVADLMAQAGSDRARFTP
MAB_1662c|M.abscessus_ATCC_199 PIDHVGVQRLKNGLNAIGISAIAGRVSGTILSAIADLAEKAGSNRVALTP
********:**** **:*::.********** :*:* **.:* :**
Mflv_2686|M.gilvum_PYR-GCK YQKLIVLDVPDDKLDELRAGLDALGLPSTPSHWRRNLMACTGIEFCKLSF
Mvan_3857|M.vanbaalenii_PYR-1 YQKLIILDVADENVAKLVEQLDALGLPSTPSHWRRNLMACTGIEFCKLSF
MSMEG_4527|M.smegmatis_MC2_155 YQKLIILDVPDDKIDELRAGLDALGLPSTPSHWRRNLMACTGIEFCKLSF
Rv2391|M.tuberculosis_H37Rv YQKLVILDIPDALLDDLIAGLDALGLQSRPSHWRRNLMACSGIEFCKLSF
Mb2412|M.bovis_AF2122/97 YQKLVILDIPDALLDDLIAGLDALGLQSRPSHWRRNLMACSGIEFCKLSF
MMAR_3710|M.marinum_M YQKLVILDIPDDKLDETIAGLQALGLRAQPSHWRRNLMACSGIEFCKLSF
MUL_3652|M.ulcerans_Agy99 YQKLVILDIPDDKLDETIAGLQALGLRAQPSHWRRNLMACSGIEFCKLSF
MAV_1787|M.avium_104 YQKLVLLDIPDDKLDEVVAGLEALGLQSQPSHWRRNLMACSGIEFCKLSF
TH_1443|M.thermoresistible__bu YQKLIVLDIADDKLDEFTAGLDRLGLQWQPSHWRRNLMACTGIEFCKLSF
MAB_1662c|M.abscessus_ATCC_199 HQKLIILDVSDDELPALEAGLNALGLPSRPSHWRKNLLACTGIEYCKLSF
:***::**:.* : *: *** *****:**:**:***:*****
Mflv_2686|M.gilvum_PYR-GCK AETRSRSQVLVPELEKRLEDINAQLDVPVTININGCPNSCARIQVADIGF
Mvan_3857|M.vanbaalenii_PYR-1 AETRSRSQVLVPELEKRLDDINAQLDVPVTININGCPNSCARIQVADIGF
MSMEG_4527|M.smegmatis_MC2_155 AETRKRAQVLVPELEKRLDDINAQLDVPITVNINGCPNSCARIQVADIGF
Rv2391|M.tuberculosis_H37Rv AETRVRAQHLVPELERRLEDINSQLDVPITVNINGCPNSCARIQIADIGF
Mb2412|M.bovis_AF2122/97 AETRVRAQHLVPELERRLEDINSQLDVPITVNINGCPNSCARIQIADIGF
MMAR_3710|M.marinum_M AETRVRAQSLVPELEERLDDLNSTLDVPVTVNINGCPNSCARIQVADIGF
MUL_3652|M.ulcerans_Agy99 AETRVRAQSLVPELEERLDDINSTLDVPVAVNINGCPNSCARIQVADIGF
MAV_1787|M.avium_104 AETRVRAQGLVPELERRLADVNRQLDVPITINLNGCPNSCARIQVADIGL
TH_1443|M.thermoresistible__bu TETRVRAQSLVPELEKRLEDINARLDVPITVNINGCPNSCARIQVADIGF
MAB_1662c|M.abscessus_ATCC_199 TETRVRAQSLVPELEKRLDDLNAQIDTPVTINMNGCPNSCARSQTADIGF
:*** *:* ******.** *:* :*.*:::*:********* * ****:
Mflv_2686|M.gilvum_PYR-GCK KGQMVDDGDG-PEEGFQVHLGGSLGLDSGFGRKLRQHKVVATELGDYIER
Mvan_3857|M.vanbaalenii_PYR-1 KGQMVDDGNG-PEEGFQVHLGGSLGLDSGFGRKLRQHKVLATELGDYIER
MSMEG_4527|M.smegmatis_MC2_155 KGQMVDDGNG-PEEGFQVHLGGSLGLDSGFGRKLRQHKVLSSELGDYIER
Rv2391|M.tuberculosis_H37Rv KGQMIDDGHGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDR
Mb2412|M.bovis_AF2122/97 KGQMIDDGHGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDR
MMAR_3710|M.marinum_M KGQMVDDGAGGQVEGFQVHLGGSLGLDSGFGRKLRQHKVTSDELGDYIDR
MUL_3652|M.ulcerans_Agy99 KGQMVDDGAGGQVEGFQVHLGGSLGLDSGFGRKLRQHKVTSDELGDYIDR
MAV_1787|M.avium_104 KGQMVDDGEGGSVEGFQVHLGGSLGQDSGFGRKLRQHKVTSDELGDYIER
TH_1443|M.thermoresistible__bu KGMIVDDGDG-PEEGFQVHLGGGLGLDSGFGRKLRQHRVLSSELGDYIDR
MAB_1662c|M.abscessus_ATCC_199 KGQMVDDGNGNSVEGFQVHLGGSLGLDSGFGRKLRQHKVTSTELGDYIDR
** ::*** * ********* ** *:*********:* : ******:*
Mflv_2686|M.gilvum_PYR-GCK VVRNFVKQREQGERFATWALRADDADLR
Mvan_3857|M.vanbaalenii_PYR-1 VVRNFVKQREDGERFATWALRADEADLR
MSMEG_4527|M.smegmatis_MC2_155 VVRNFVKQREDGERFAQWAVRADEADLR
Rv2391|M.tuberculosis_H37Rv VVRNFVKHRSEGERFAQWVIRAEEDDLR
Mb2412|M.bovis_AF2122/97 VVRNFVKHRSEGERFAQWVIRAEEDDLR
MMAR_3710|M.marinum_M VVRNFVKNRAAGERFAQWAIRAEEDDLR
MUL_3652|M.ulcerans_Agy99 VVRNFVKNRAAGERFAQWAIRAEEDDLR
MAV_1787|M.avium_104 VARNFLKYRGEGERFAQWAMRADEDDLR
TH_1443|M.thermoresistible__bu VVRNFVKQREDGERFATWALRADEADLR
MAB_1662c|M.abscessus_ATCC_199 VVRNFVAQRTDGERFAQWAVRAEEADLR
*.***: * ***** *.:**:: ***