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WYLSVAPDELAAAATELRDVGSIVSTVNAAAAVPTTALWPAAADEVSAAIAALFSSHAQQYQSLSVQVAA YHDQFVRALAAGGASYSLAEAASASPLEQLLDLINLPSQTLLGRPLIGDGADGTASAPNGGAGGLLYGNG GNGYDNSASAGVAGGAGGSAGLIGNGGIGGAGGALAAGGAGGTGGLLFGNGGSGGAGGLGAVGGQGGGAG TLSLVGSGGDGGHGGEGTPGGSGGTGGGGGSAGLFGRGGFGGSGGTGGDGVVGSPAALDGGAGGTGGSGG RGGLFAVGGDGGHGGIGGNGARGADGVGDGESGTAGGNGGAGGAGGVGGTGILSGSDGVGGGGGNGGRGG DGIRGADGVLDGESGYLGGSGGAGGAGGAGGGGSQVGSDGVGGAGGTGGAGGHGARGADGLLDGEAGSKG GAGGGGGAGGAGGAGSQAGSDGVGGAGGDGGDGGHGAYGDGKAGGGGGAGGRGGDGGDGDTGGAAGNGGD GGEGGNAVANSGRGGGTGGAGGVGGDGGNGTNGVGGAGGHGGMGGNAGSSDAANGAVGSRGGDGGAGGKG GQGTTGGDGGNGGSAGKGGTGGSAVQTNDAGNGGDGGAGGDGGIGTLGPGGDGGAGGNGGSGGDGNTQPV GHSLGGGGGVGGNGGQGGAGGQGITGGSGGAGGSGGNGGTGGDDTENAEPSAGGAGGEGGMGGGGGDGVV GTGGMGGGGGQGGAGGDAIDSVGGIGGKGGGGADGGGGGASSTSTGGAPGGVGGDGDDGDPPTGQTGGGG GTGGGGGAPGVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3105 | - | - | 100% (783) | PE-PGRS family protein |
| M. marinum M | MMAR_3758 | - | 0.0 | 51.73% (868) | PE-PGRS family protein |
| M. marinum M | MMAR_2033 | - | 0.0 | 48.86% (925) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 0.0 | 50.93% (856) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-156 | 44.96% (754) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 51.17% (854) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-11 | 36.46% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-50 | 36.25% (411) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-23 | 42.39% (184) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-138 | 40.92% (826) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-48 | 42.81% (299) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2354 | - | 0.0 | 93.10% (652) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-157 | 43.90% (779) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3105|M.marinum_M --------------------------------------------------
MUL_2354|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3105|M.marinum_M ----------MWYLSVAPDELAAAATELRDVGSIVSTVNAAAAVPTTALW
MUL_2354|M.ulcerans_Agy99 ----------MWYLSVAPDELAAAATELRGVGSIVSTVNAAAAVPTTALW
Mb1121|M.bovis_AF2122/97 ----------MSFVIAAPEALVAVASDLAGIGSALAEANAAALAPTTALL
Rv1091|M.tuberculosis_H37Rv ----------MSFVIAAPEALVAVASDLAGIGSALAEANAAALAPTTALL
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAAT
MMAR_3105|M.marinum_M PAAADEVSAAIAALFSSHAQQYQSLSVQVAAYHDQFVRALAAGGASYSLA
MUL_2354|M.ulcerans_Agy99 PAAADEVSAAIAALFSSHAQQYQSLSVQVAAYHDQFVRALAAGGASYSLA
Mb1121|M.bovis_AF2122/97 AAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQALTGGGGAYAAA
Rv1091|M.tuberculosis_H37Rv AAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQALTGGGGAYAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRI
MMAR_3105|M.marinum_M EAASAS--------------------------------PLE----QLLDL
MUL_2354|M.ulcerans_Agy99 EAASAS--------------------------------PLE----QLLDL
Mb1121|M.bovis_AF2122/97 EAANVS--------------------------------AAQSTDQRLLDL
Rv1091|M.tuberculosis_H37Rv EAANVS--------------------------------AAQSTDQRLLDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 PSILSP---------------------------------------SLLSP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DNVMLVS--------------------------------AFLAAAALAQN
MMAR_3105|M.marinum_M IN--------------------LPSQTLLG--------RPLIGDGADGTA
MUL_2354|M.ulcerans_Agy99 IN--------------------LPSQTLLG--------RPLIGDGADGTA
Mb1121|M.bovis_AF2122/97 IN--------------------GPTQALLG--------RPLIGDGANG-G
Rv1091|M.tuberculosis_H37Rv IN--------------------GPTQALLG--------RPLIGDGANG-G
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD------------------------------------NDFLSHNDTDFA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VG------------------------GAMG----YERTAVLLVEPDTATL
MMAR_3105|M.marinum_M SAPNGGAGGLLYGNGGNGYDNSASAGVAGGAGGSAGLIG-NGGIGGAGGA
MUL_2354|M.ulcerans_Agy99 SAPNGGAGGLLYGNGGNGYDNSASAGVAGGAGGSAGLVG-NGGIGGAGGA
Mb1121|M.bovis_AF2122/97 PGQDGGPGGLLYGNGGNG-GTSTTAGVAGGNGGAAGLIG-NGGAGGGGGA
Rv1091|M.tuberculosis_H37Rv PGQDGGPGGLLYGNGGNG-GTSTTAGVAGGNGGAAGLIG-NGGAGGGGGA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSG-WNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSG-WNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHG-YDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA
TH_3810|M.thermoresistible__bu ----------VDGDGGSG----------GRTGLFSKLSR--GGDGGDGGL
MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG-DLQFGNRDTTAIGDGAV
MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQA--------LTAAANTLEGLSAATVASNAAAAQ
MAV_4827|M.avium_104 AVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLV
: .
MMAR_3105|M.marinum_M LAAGGAGGTGG--LLFGNGGSGGAGG--------------LGAVGGQGGG
MUL_2354|M.ulcerans_Agy99 LAAGGAGGTGG--LLFGNGGSSGAGG--------------LGAVGGQGGG
Mb1121|M.bovis_AF2122/97 GAAGGNGGAGG--WLYGNGGAGGAGGTSVI----------PGVAGGNGGA
Rv1091|M.tuberculosis_H37Rv GAAGGNGGAGG--WLYGNGGAGGAGGTSVI----------PGVAGGNGGA
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGT
TH_3810|M.thermoresistible__bu GGNGGHGGGTGIISLLSLAGNGGNGG-------------------NGYRT
MAB_4284c|M.abscessus_ATCC_199 AVGGSNSGPIAS----GQGSTAVNGDVRDS----------NIINADHGSN
MLBr_01183|M.leprae_Br4923 LTTEIAPPAADDVSILLAHFFSGHGR--------------------QYQA
MAV_4827|M.avium_104 GSGVDVAPLKQVLQTTTFLDVSVAEEPE------------TALARGAALA
.
MMAR_3105|M.marinum_M AGTLSLVGSGGD-----GGHGGEG------TPGGSG--------------
MUL_2354|M.ulcerans_Agy99 AGTLSLVGSGGD-----GGHGGEG------TPGGSG--------------
Mb1121|M.bovis_AF2122/97 GGSAGLWGTGGA-----GGDGGNGRSGPVNVAGSAG--------------
Rv1091|M.tuberculosis_H37Rv GGSAGLWGTGGA-----GGDGGNGRSGPVNVAGSAG--------------
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
TH_3810|M.thermoresistible__bu TDNNALDG------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS--------------
MLBr_01183|M.leprae_Br4923 HAS-----------------------------------------------
MAV_4827|M.avium_104 AANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVP-------------
MMAR_3105|M.marinum_M --GTGGGGGSAGLFGRGG------FGGSGGTGGDG---------------
MUL_2354|M.ulcerans_Agy99 --GTGGGG-SAGLFGRGG------FGGSGGTGGDG---------------
Mb1121|M.bovis_AF2122/97 --GNGGAGGAAGLFGDAG------AGGNGGKGGAGGAA------------
Rv1091|M.tuberculosis_H37Rv --GNGGAGGAAGLFGDAG------AGGNGGKGGAGGAA------------
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
TH_3810|M.thermoresistible__bu --GHGGNGGNVGFFSLFN--------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---QRNTTNINDSFNTDR------STNIGSGNTTN---------------
MLBr_01183|M.leprae_Br4923 ----QGATNHQDLIQSLL--------------------------------
MAV_4827|M.avium_104 --VDPEPGDDELAYSAVGEEDAESPTVVIEK-------------------
MMAR_3105|M.marinum_M VVGSPAALDG------GAGGTGGSGGRG--------------GLFAVGGD
MUL_2354|M.ulcerans_Agy99 VVGSPAALDG------GAGGTGGSGGRG--------------GLFAVGGD
Mb1121|M.bovis_AF2122/97 FSINFTAGDG------GAGGAGGSGGHA--------------LLWGAGGA
Rv1091|M.tuberculosis_H37Rv FSINFTAGDG------GAGGAGGSGGHA--------------LLWGAGGA
Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG---------------TGANGGA
Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
TH_3810|M.thermoresistible__bu -----------------LGGAGGWGGSG----------------------
MAB_4284c|M.abscessus_ATCC_199 TEIGSHNQAN-------IGTSTSAGGSA--------------AVGGNAGL
MLBr_01183|M.leprae_Br4923 ------------------TSSSAYAGTE----------------------
MAV_4827|M.avium_104 -LFLPEDSEP-------RRRPVLLVGSG----------------LAVVGI
*
MMAR_3105|M.marinum_M GGHGGIGGNGARG----------------ADGVGDGESGTAGG-------
MUL_2354|M.ulcerans_Agy99 GGHGGIGGNGARG----------------ADGVGDGESGTAGG-------
Mb1121|M.bovis_AF2122/97 GGNGGSGGTGGAG----------------GSTAGAGGNGGAGGGGGTGGL
Rv1091|M.tuberculosis_H37Rv GGNGGSGGTGGAG----------------GSTAGAGGNGGAGGGGGTGGL
Mflv_5091|M.gilvum_PYR-GCK GGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
TH_3810|M.thermoresistible__bu -----VDGVDVVG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAG------------------------------------
MLBr_01183|M.leprae_Br4923 -----TANHDSL--------------------------------------
MAV_4827|M.avium_104 SAVLALEIALAIG-------------------------------------
MMAR_3105|M.marinum_M ----NGGAGGAGGVGGTGILSG----SDGVGGGG----------------
MUL_2354|M.ulcerans_Agy99 ----NGGAGGAGGVGGTGISSG----SDGVGGGG----------------
Mb1121|M.bovis_AF2122/97 L-FGNGGAGGHGAAAGNGLAAGNGVSSSGGGGAG----------------
Rv1091|M.tuberculosis_H37Rv L-FGNGGAGGHGAAAGNGLAAGNGVSSSGGGGAG----------------
Mflv_5091|M.gilvum_PYR-GCK --GTAGGTGGVGGIGGAGSTGA----VGGVGGKG----IQGGQG------
Mvan_1264|M.vanbaalenii_PYR-1 --GTEGGTGGVGGVGGVGATGG----AGGVGGKG----IQGGQG------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATG----ADSLGGRGGTSWVQAGYGPTTGGK
TH_3810|M.thermoresistible__bu ----GNPDGGTPGAHGESHTPG----------------------------
MAB_4284c|M.abscessus_ATCC_199 ----NAGLAGNAGLAGNAGLAG------NAGLAG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --IRTTGTVALQPTPNQHLIVP----------------------------
MMAR_3105|M.marinum_M -------GNGGRGGDGIRGADG--VLDGES-------------------G
MUL_2354|M.ulcerans_Agy99 -------GNGGRGGDGIRGADG--VLDCES-------------------G
Mb1121|M.bovis_AF2122/97 -------GTGGAGGDGGAGGAGGNARLWGV-------------------G
Rv1091|M.tuberculosis_H37Rv -------GTGGAGGDGGAGGAGGNARLWGV-------------------G
Mflv_5091|M.gilvum_PYR-GCK -------LQGGKGGDGGAGGKGGDADSMGS------------------AG
Mvan_1264|M.vanbaalenii_PYR-1 -------LQGGQGGDGGTGGTGGDATSMGE------------------AG
MSMEG_0868|M.smegmatis_MC2_155 ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAAS
TH_3810|M.thermoresistible__bu -------VYTDRQGEDGEDGTG---------------------------T
MAB_4284c|M.abscessus_ATCC_199 --------NAGLAGNAGLAGNAGLAGN----------------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------TEQAPAPPPVQASAPQPKISVP-------------------E
MMAR_3105|M.marinum_M YLGGSGGAGGAGG---------------------AGG-GGSQVGS-----
MUL_2354|M.ulcerans_Agy99 YLGGSGGAGGAGG---------------------AGG-GGSQVGS-----
Mb1121|M.bovis_AF2122/97 GAGGAGGDGGAGG---------------------AGGKGGSGLSG-----
Rv1091|M.tuberculosis_H37Rv GAGGAGGDGGAGG---------------------AGGKGGSGLSG-----
Mflv_5091|M.gilvum_PYR-GCK ATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD------
Mvan_1264|M.vanbaalenii_PYR-1 ATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN------
MSMEG_0868|M.smegmatis_MC2_155 ANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAY
TH_3810|M.thermoresistible__bu GIGGRGGNGGSSS-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG---------------------LAGNAGLAGN------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVAAPKPLSPPVAAP-------------------LPAAPPPAAPP-----
MMAR_3105|M.marinum_M ----------------DGVGGAG---GTGG-AGGHGARG-----------
MUL_2354|M.ulcerans_Agy99 ----------------DGVGGAGGAGGTGG-AGGHGARG-----------
Mb1121|M.bovis_AF2122/97 ----------------NANGGAGGDSGRGG-TGGAGGEGG----------
Rv1091|M.tuberculosis_H37Rv ----------------NANGGAGGDSGRGG-TGGAGGEGG----------
Mflv_5091|M.gilvum_PYR-GCK ----------------GGTGGAGGAGGTGG-TGGAGGTGG----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------GGTGGNGGNGGTGG-TGGNGGTGG----------
MSMEG_0868|M.smegmatis_MC2_155 DPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQ
TH_3810|M.thermoresistible__bu -----------------------------G-THPMAEDGE----------
MAB_4284c|M.abscessus_ATCC_199 ----------------AGLAGNAGLAGNAGLAGNAGLAGN----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------LPEAPPIPAAPPVVPVPVVVPP----------
MMAR_3105|M.marinum_M ------ADGLLDGEAGSKGGAGGGGGAGGAGGAGSQAGSD-GVGGAGGDG
MUL_2354|M.ulcerans_Agy99 ------ADGLLDGEAGSKGGAGGGGGAGGAGGAGSQAGSD-GVGGAGGDG
Mb1121|M.bovis_AF2122/97 ------AAGLLVGTGG-HGGDGGAGGAAVKGGDGGAAAGT-GIAGAGGRG
Rv1091|M.tuberculosis_H37Rv ------AAGLLVGTGG-HGGDGGAGGAAVKGGDGGAAAGT-GIAGAGGRG
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGIGG-AGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGIGG-AGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 HSTGQTDTGGNGGRGG-DGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHG
TH_3810|M.thermoresistible__bu ------HVKALDGRPGLDGGNGSHGGNGGHGGRGGFLGIG----GSGGWG
MAB_4284c|M.abscessus_ATCC_199 --------AGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAA--VAGNAAVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----VPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPP
MMAR_3105|M.marinum_M GDGGHGAYG-DGKAGGGG----GAGGRGGDGGDGDTG---------GAAG
MUL_2354|M.ulcerans_Agy99 GDGGHGAYG-DGKAGGGG----GAGGRGGDGGDGDTG---------GAAG
Mb1121|M.bovis_AF2122/97 GAGGSGGSGGDGGGGAAG----PAGWLFGDGGAGGNG---------GAAA
Rv1091|M.tuberculosis_H37Rv GAGGSGGSGGDGGGGAAG----PAGWLFGDGGAGGNG---------GAAA
Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGG
TH_3810|M.thermoresistible__bu GHGGNGGD---------------TDADGGNGGDGGNG---------GSAG
MAB_4284c|M.abscessus_ATCC_199 GVLNTGVSGAIGGSSHVG-----GAINESLGGSGSVG---------GSTA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QVGGTVPQSPPQHQTPPG-----EGTPPKPDGPGNYGG--------GHVP
MMAR_3105|M.marinum_M NGGDGGEG--------------GNAVANSGR------GGGTGGAGG----
MUL_2354|M.ulcerans_Agy99 NGGDGGEG--------------GNAVANSGR------GGGTGGAGG----
Mb1121|M.bovis_AF2122/97 AGGAGGQA--------------GGGGGNGG-------NGGNGGNGG----
Rv1091|M.tuberculosis_H37Rv AGGAGGQA--------------GGGGGNGG-------NGGNGGNGG----
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu RGGTGGLR------------------------------GVFGINGG----
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTG--------------VGGGVSTG--------VGVGSHVG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TPGAGGSG--------------GSGGGHVP-------TPGAGGSGG----
MMAR_3105|M.marinum_M -------------VGGDGGNG--TNGVGGAG-------------------
MUL_2354|M.ulcerans_Agy99 -------------VGGDGGNG--TNGVGGAG-------------------
Mb1121|M.bovis_AF2122/97 -------------NGGNGATGGWLYGNGGAG-------------------
Rv1091|M.tuberculosis_H37Rv -------------NGGNGATGGWLYGNGGAG-------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu ------------------------NGRAGLG-------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------GGISESLGGSGSVG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------SGGGHVPTPGTGGPG-------------------
MMAR_3105|M.marinum_M ----GHGGMGGNAGSSD-----------AANGAVGSRG--------GDGG
MUL_2354|M.ulcerans_Agy99 ----GHGGMGGNAGSSD-----------AANGAVGSRG--------GDGG
Mb1121|M.bovis_AF2122/97 ----GQGATAGAGGAGANGVSSTNGG---GNGGIGGTG--------GSGG
Rv1091|M.tuberculosis_H37Rv ----GQGATAGAGGAGANGVSSTNGGGTGGNGGIGGTG--------GSGG
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGT----------GGTGGTGGTG--------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGT----------GGTGGTGGTG--------GTGG
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGN----------GGQGTIEANGPSAVASGIGAGG
TH_3810|M.thermoresistible__bu ----GRGXX-------------------------------------XXGG
MAB_4284c|M.abscessus_ATCC_199 ----GSTAVGGGAHTG--------------VGGGVSTG-------VGVGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----GTGGSGGGHVPTPG------------------AG--------TPGG
MMAR_3105|M.marinum_M AGGKG---GQGTTGGDGGNGGSAGKGGTGGSAVQTNDAGNG---GDGGAG
MUL_2354|M.ulcerans_Agy99 DGGKG---GQGTTGGDGGNGGSAGKGGTGGAAAQTNDAGDG---GDG---
Mb1121|M.bovis_AF2122/97 AGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAG---GDGGDG
Rv1091|M.tuberculosis_H37Rv AGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAG---GDGGDG
Mflv_5091|M.gilvum_PYR-GCK AGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKG
Mvan_1264|M.vanbaalenii_PYR-1 AGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKG
MSMEG_0868|M.smegmatis_MC2_155 NGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQG
TH_3810|M.thermoresistible__bu GVGAAVRSGNGVFSGGGGTP-SAGFGVPTTIQFPAGSCTSR---------
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SGGGHLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGG---------
MMAR_3105|M.marinum_M GDGGIGTLGPGGDGGAGGNGGSGGDGNTQPVGHSLGGGGGV---------
MUL_2354|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 GNGGAGGTG-GLLFGAGGNGGPGGSGGAADIGGNGGAGNGG---------
Rv1091|M.tuberculosis_H37Rv GNGGAGGTG-GLLFGAGGNGGPGGSGGAADIGGNGGAGNGG---------
Mflv_5091|M.gilvum_PYR-GCK GLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQG
Mvan_1264|M.vanbaalenii_PYR-1 GLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQG
MSMEG_0868|M.smegmatis_MC2_155 GNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------SHVGGGISESLGGSGSVGGSTAVG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3105|M.marinum_M ------GGNGGQGGAGGQGITGGSGGAGGSGGNGGTGGDDTENAEPSAGG
MUL_2354|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 ------GTDGNGGNGGSGGGAGSGGDGGGAGGNGAWLFGNGGAGGGGGKG
Rv1091|M.tuberculosis_H37Rv ------GTDGNGGNGGSGGGAGSGGDGGGAGGNGAWLFGNGGAGGGGGKG
Mflv_5091|M.gilvum_PYR-GCK ATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTN
Mvan_1264|M.vanbaalenii_PYR-1 ATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTN
MSMEG_0868|M.smegmatis_MC2_155 TTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------GGAHT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3105|M.marinum_M AGGEGGMGGGGGDGVVGTGGMGGGGG--------QGGAGGDAIDSVGGIG
MUL_2354|M.ulcerans_Agy99 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 GNGAGGGLGGGSFGLPGLNGSGGDGG--------DGGNGAPG-GVLYGNG
Rv1091|M.tuberculosis_H37Rv GNGAGGGLGGGSFGLPGLNGSGGDGG--------DGGNGAPG-GVLYGNG
Mflv_5091|M.gilvum_PYR-GCK GA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDA-GSGGSG-
Mvan_1264|M.vanbaalenii_PYR-1 GA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDP-GSEAVD-
MSMEG_0868|M.smegmatis_MC2_155 GAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDG-GVNGTGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAINDALGGSGSVGGSTAVGGGAHTS------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_3105|M.marinum_M GKGGGGADGG-----------GGGASSTSTGGAPGGVGGD----------
MUL_2354|M.ulcerans_Agy99 -----------------------GASSTSTGGAPGGVGGD----------
Mb1121|M.bovis_AF2122/97 GAGGQGSSGG-----------IGGPGATGGAGGKGGDGGDAQL----IGD
Rv1091|M.tuberculosis_H37Rv GAGGQGSSGG-----------IGGPGATGGAGGKGGDGGDAQL----IGD
Mflv_5091|M.gilvum_PYR-GCK INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GG
Mvan_1264|M.vanbaalenii_PYR-1 INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GG
MSMEG_0868|M.smegmatis_MC2_155 ASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGG
TH_3810|M.thermoresistible__bu -----------------------AVSREGIMPSSRAASAR----------
MAB_4284c|M.abscessus_ATCC_199 ---------------------AINESMNSSINASHSSSMN----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------HAPAPGGGLGGGGGHAPAP---------
MMAR_3105|M.marinum_M ----GDDGDPPTGQTG--GGGGTGGGGGAPGVV------------
MUL_2354|M.ulcerans_Agy99 ----GDDGDPPTGQTG--GGG-TGGGGGAPGVV------------
Mb1121|M.bovis_AF2122/97 GGNGGNGGAGGTGGTP--GPGGPGGSGGLGGLLFGQTGTAGVSP-
Rv1091|M.tuberculosis_H37Rv GGNGGNGGAGGTGGTP--GPGGPGGSGGLGGLLFGQTGTAGVSP-
Mflv_5091|M.gilvum_PYR-GCK AGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSG-GSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAG-GSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTP-GTAGTTGANNP
TH_3810|M.thermoresistible__bu ------AGAACASSTS-----RSRRSFCCSRA-------------
MAB_4284c|M.abscessus_ATCC_199 ESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH----
MLBr_01183|M.leprae_Br4923 ---------------------------------------------
MAV_4827|M.avium_104 ---GGGLGGFGGGHSG----GGLGGLGGGHK--------------