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M. marinum M MMAR_2964 (-)

annotation: transmembrane transport protein
coordinates: 3581248 - 3584406
length: 1052

MAVQPLSPTRKAPPVGDAEPDRPGRLGGPHFRLGRRRQPSPATVLLVAAFGAFLAFLDSTIVNVAFPDIQ
RYFHSGISDLSWVLNAYNIVFAAFLVAAGKLADLLGRKRLFVYGVVLFTIASGLCAAADSVEQLVAFRVL
QGIGAAVLVPASLGLVVESFPAERRAHGVNLWGAAGAIAAGLGPPIGGALVEALNWRWVFLVNLPLGIVA
VLAARRALVESRACGRRRVPDVRGAAMLATALGLLTLGLIKGPDWGWSSLPAIGSLVAAALAMIGFVMSS
RNHPTPLVEPALLRIRSFVAGSALTAIASAGFYAYLLTHVLFLNYVWGYTLLQAGLAVCPAAIIAAVTAG
LLGRVADRHGYRVIIGVGALIWAGSLLWYLTCVGTTPNFLGEWLPGQILQGIGVGAAFPLLGSAALAGLA
SGSSYATASAVTGTIRQVGAVIGVALLVILVGTPAPGAAEESLRRGWTMAAICFVAVALGAVWLGRIRPA
PAEAVTPESAPPAQAPLPQPSVAPVVSTSPDIDVLQAVPDLHRHAEHVELQAGSYLFRAGDVSDSLYVVR
SGRLQVIDEHGLVAELGRGQLVGEVGVLRDAPRSASVLAVRDSSLLRVPKSEFAKIADARLLGVLASVLA
NRQVPTSRTASRPPTREVVVAVIGVDAGAPATVVATELCAALSQRLRAVAPGRVNADGLERAERSADRVV
LQATVGDGPWLDFCVRVADRVVLVARDFLAPPRRLTAKAPGVDLVLTGPSAAPVYRREWEELITPRSVHT
VHPATIADDLRPLAARIAGRSVGLVLGGGGALACAHLGVLEELEAAGITVDRYAGTSMGALMAALAADGV
DAAGVDAYIYEYFVRKNHSDFTLPSKGFLRGKRTEVALRSAFGDRLVEELPKQFRCVSVDLLARQSVVHR
SGLLTDVISCSMRLPVMYPPMAHAGSLHVDGGILDNVPVTALAGPEGPVIAVNVAGGNRDSAPDSRHGKR
LQVPGITDTLLRALTIGSAMTSSEVLAHADVVIQPNPSGIGFLEFHQIDRAREAGRMAARQALPQIMKLV
FP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2964--100% (1052)transmembrane transport protein
M. marinum MMMAR_1306-0.061.17% (1056) transmembrane transport protein
M. marinum MMMAR_0729-0.061.89% (1039) transmembrane transport protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3755-0.072.43% (1059) hypothetical protein Mb3755
M. gilvum PYR-GCKMflv_0301-1e-5833.48% (457) EmrB/QacA family drug resistance transporter
M. tuberculosis H37RvRv3728-0.072.52% (1059) hypothetical protein Rv3728
M. leprae Br4923MLBr_01562-7e-5030.25% (519) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_1396-1e-5332.39% (423) EmrB/QacA family drug resistance transporter
M. avium 104MAV_1387-3e-5131.97% (416) drug transporter
M. smegmatis MC2 155MSMEG_5670-3e-5732.11% (464) efflux membrane protein
M. thermoresistible (build 8)TH_3965-7e-5032.55% (424) PUTATIVE drug transporter
M. ulcerans Agy99MUL_3590-0.061.79% (1039) transmembrane transport protein
M. vanbaalenii PYR-1Mvan_4014-2e-5432.73% (440) EmrB/QacA family drug resistance transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0301|M.gilvum_PYR-GCK          ------------------------------------------MTGLRMGT
MSMEG_5670|M.smegmatis_MC2_155      ----------------------------------------MNETVGALSA
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------VTSVDAGRSTMSEVFTAYAPRSAA
Mvan_4014|M.vanbaalenii_PYR-1       ----------------------------------MSQHRPHDAIAAEPTD
MAB_1396|M.abscessus_ATCC_1997      ---------------------------------------------MRPEY
Mb3755|M.bovis_AF2122/97            --------------MHTVATNNAAPVIAAGPVGPSRRRRRVHAPLTRRRQ
Rv3728|M.tuberculosis_H37Rv         --------------MHTVATNNAAPVIAAGPVGPSRRRRRVHAPLTRRRQ
MMAR_2964|M.marinum_M               ------------MAVQPLSPTRKAPPVGDAEPDRPGRLGGPHFRLGRRRQ
MUL_3590|M.ulcerans_Agy99           --------------MHLSAPAERS-------------------ALTSRRQ
MLBr_01562|M.leprae_Br4923          MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          AAGRWVLLATVLG--SGIVMVDATVVNVALPHIAADLGG-GFGDLQWVVN
MSMEG_5670|M.smegmatis_MC2_155      RRKAIILVSCCLS--LLIVSMDATIVNVAIPSIRSDLGA-SPSQLQWVID
MAV_1387|M.avium_104                ---------MMIG--FFMIMVDSTIVAIANPTIMADLHI-GYDTVVWVTS
TH_3965|M.thermoresistible__bu      ANPWHALWAMLIG--FFMILVDATIVPVANLEIMADLGA-DYTAVIWVTS
Mvan_4014|M.vanbaalenii_PYR-1       DHPFRALWVMMVG--FFLIVVDSTVIAVANPVLKNDFDV-EYHSVIWVTS
MAB_1396|M.abscessus_ATCC_1997      PRPWITLWVVLFG--LFMILLDSTIVSVANPAIKAGFGA-DYSSTVWVTS
Mb3755|M.bovis_AF2122/97            PSSSAVLLVAAFG--AFLAFLDSTIVNVAFPDIQRHFHS-DISDLSWMLN
Rv3728|M.tuberculosis_H37Rv         PSSSAVLLVAAFG--AFLAFLDSTIVNVAFPDIQRHFHS-DISDLSWMLN
MMAR_2964|M.marinum_M               PSPATVLLVAAFG--AFLAFLDSTIVNVAFPDIQRYFHS-GISDLSWVLN
MUL_3590|M.ulcerans_Agy99           PSATAVLLVASFG--AFLAFLDSTIVNIAFPHIQRSFPSYDISSLSWILN
MLBr_01562|M.leprae_Br4923          PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSL-SDAGRSWGIT
                                               ..    :  :*:*:  :*   :   :         *   

Mflv_0301|M.gilvum_PYR-GCK          AYTLTLASLILLGGSLGDHFGRRKVFVLGVVWFALASIACGLAPSIEVLI
MSMEG_5670|M.smegmatis_MC2_155      VYTLVLASLLLLAGATGDRFGRRRTFHLGLTVFAVASLLCSVAPNIETLI
MAV_1387|M.avium_104                AYLLGYAVVLLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLI
TH_3965|M.thermoresistible__bu      AYLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLAGTIGMLI
Mvan_4014|M.vanbaalenii_PYR-1       GYLLAFAAFLLIGGRLGDRFGSKPVYLVGLTLFAAASVWCGLSTSVGMLI
MAB_1396|M.abscessus_ATCC_1997      AYLLGYAVPLLITGRLGDQFGPRSMYLSGLAVFTAASLWCGLAGSIGWLI
Mb3755|M.bovis_AF2122/97            AYNIVFAAFLVAAGRLADLMGRKRVFILGVALFTVASGLCAIAESVGELV
Rv3728|M.tuberculosis_H37Rv         AYNIVFAAFLVAAGRLADLMGRKRVFILGVALFTVASGLCAIAESVGELV
MMAR_2964|M.marinum_M               AYNIVFAAFLVAAGKLADLLGRKRLFVYGVVLFTIASGLCAAADSVEQLV
MUL_3590|M.ulcerans_Agy99           GYNIVFAAFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAGDVEQLV
MLBr_01562|M.leprae_Br4923          AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLV
                                     * :  .  ::  *  .* :* :  :  *:. *: :*  *. :     *:

Mflv_0301|M.gilvum_PYR-GCK          VARALQGVGGALLTPGSLALISAAFAS-GDRGAAVGAWSGLGGIAGAIGP
MSMEG_5670|M.smegmatis_MC2_155      AARLLQAIGGSMLNPVAMSIITQVFTGRVERARAIGVWGSVVGISMALGP
MAV_1387|M.avium_104                AARVVQGVGAGVMTPQTLSTITRIFPA-ERRGVAVSVWSATAGAASLAGP
TH_3965|M.thermoresistible__bu      AARVLQGLGAALLTPQTLSMITRIFPA-DRRGVPMGVWGATAGVATLIGP
Mvan_4014|M.vanbaalenii_PYR-1       AARVAQGVGAALLTPQIMSTITRTFPP-QRHGMAMSVWGATAGVGMLAGP
MAB_1396|M.abscessus_ATCC_1997      AARVVQGIGAAMLTPQTLTVVQRVFPP-ERRGTAMGVWGAVAGIATLVGP
Mb3755|M.bovis_AF2122/97            AFRVLQGIGAAVLVPASLGLVVEAFPA-ERRAHGVNLWGAAGAIAAGLGP
Rv3728|M.tuberculosis_H37Rv         AFRVLQGIGAAVLVPASLGLVVEAFPA-ERRAHGVNLWGAAGAIAAGLGP
MMAR_2964|M.marinum_M               AFRVLQGIGAAVLVPASLGLVVESFPA-ERRAHGVNLWGAAGAIAAGLGP
MUL_3590|M.ulcerans_Agy99           GFRVLQGIGAAVLVPASLALVVEGFDA-SHRAHAVGLWGAAAAVASGLGP
MLBr_01562|M.leprae_Br4923          IARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGL
                                      *  *.:*..:  *  :  :   *     :      :..  . .   * 

Mflv_0301|M.gilvum_PYR-GCK          FLGGALVEWN-WRAAFLINVPLAAFVIAVTLLRVPESRDPSASRRLDVGG
MSMEG_5670|M.smegmatis_MC2_155      LVGGALIEYVDWRAVFWINLPICALAILLTAIFVRESKSSTMRDVDPVGQ
MAV_1387|M.avium_104                LAGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVP--VLPTQSHRFDLVG
TH_3965|M.thermoresistible__bu      LAGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMP--RLPRQDQGFDVLG
Mvan_4014|M.vanbaalenii_PYR-1       LIGGVLLAGLGWQWIFFVNAPIGAIGIALAVRLVP--NLPGRPVRIDVVG
MAB_1396|M.abscessus_ATCC_1997      VAGGLLVDGWGWQWIFYVNVPVGVLGIILGAIYIP--RMPTHRHRLDLLG
Mb3755|M.bovis_AF2122/97            PIGGALIEADGWRWVFLVNLPLGVFAVLAARRALVENRAAGRRRVPDVRG
Rv3728|M.tuberculosis_H37Rv         PIGGALIEADGWRWVFLVNLPLGVFAVLAARRALVENRAAGRRRVPDVRG
MMAR_2964|M.marinum_M               PIGGALVEALNWRWVFLVNLPLGIVAVLAARRALVESRACGRRRVPDVRG
MUL_3590|M.ulcerans_Agy99           PVGGMLVEASSWRLVFLVNIPLGIVAVLVAGRVLTESRASGRRRVPDLRG
MLBr_01562|M.leprae_Br4923          VVGGALTEVS-WRLAFLVNVPIGLVMIYLARTALH--ETHKERMKLDAAG
                                      ** *     *:  * :* *:    :      :                

Mflv_0301|M.gilvum_PYR-GCK          AVLTVVGLGALTFGLTELGNRGASPAAVVSVGGGLVALVVFVLVEQR-SS
MSMEG_5670|M.smegmatis_MC2_155      GLGVAFLFGVVFVLIEGPGMGWTDPRTLAVAATALVAFLAFLRYESR-RH
MAV_1387|M.avium_104                VGLSGVGMLLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVR
TH_3965|M.thermoresistible__bu      MVLSAVGLFLIVFALQEAQTHRWAPWIWGTLAGGAGVMAMFVIWQSANRR
Mvan_4014|M.vanbaalenii_PYR-1       ALLSGAGICLIVLGLQEGQHERWSWWIWVAIAGGLVSITAFLRWQTVHAD
MAB_1396|M.abscessus_ATCC_1997      MALSAVGMFAFVFALQEGESFQWAPGVWAMMAAGLVVLGVFVWWQSANRG
Mb3755|M.bovis_AF2122/97            AVLLAFALGLLTLGLIKGPDWGWASLPTSGSLLAAAVAMVGFVMSSRHHP
Rv3728|M.tuberculosis_H37Rv         AVLLAFALGLLTLGLIKGPDWGWASLPTSGSLLAAAVAMVGFVMSSRHHP
MMAR_2964|M.marinum_M               AAMLATALGLLTLGLIKGPDWGWSSLPAIGSLVAAALAMIGFVMSSRNHP
MUL_3590|M.ulcerans_Agy99           AMLLGVALGLMTLGLVKGPEWGWISTATIGSFVASSVALVAFVASSRSHP
MLBr_01562|M.leprae_Br4923          AILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAE
                                                . :                          .        

Mflv_0301|M.gilvum_PYR-GCK          HPLMSPKLFADRNFGVANAVTLLIYGALGAVFLLLVLQLQTVSGFSPVAA
MSMEG_5670|M.smegmatis_MC2_155      DPFIDLRFFRSVPFASATLVAVCAFAAYGAFLFMMSLYLQSERGYSAMFT
MAV_1387|M.avium_104                EPLIPLVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRS
TH_3965|M.thermoresistible__bu      HPLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAVCGLSPTGS
Mvan_4014|M.vanbaalenii_PYR-1       EPLIPMSLMSHRNFVLSTAGIALVSFVFVSFGVPLMIYLQEVCGLSPVHA
MAB_1396|M.abscessus_ATCC_1997      EPLIPLRLFADRNFSLAGVGIASMSFCVISTGLPMMFYTQLALGFSPTKA
Mb3755|M.bovis_AF2122/97            APMVEPTLLRIQSFVAGTGLTAVASAGFYAYLLTHVLFLNYVWGYTLLEA
Rv3728|M.tuberculosis_H37Rv         APMVEPTLLRIQSFVAGTGLTAVASAGFYAYLLTHVLFLNYVWGYTLLEA
MMAR_2964|M.marinum_M               TPLVEPALLRIRSFVAGSALTAIASAGFYAYLLTHVLFLNYVWGYTLLQA
MUL_3590|M.ulcerans_Agy99           TPLIDPAFLRVRSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYSLLKA
MLBr_01562|M.leprae_Br4923          NPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRA
                                     *.:   ::                    .  .   :  :     :   :

Mflv_0301|M.gilvum_PYR-GCK          GTALLPFTIVMLLFSSRAGALSGRIGPRLPMTVGPVLAGLGLLLMLRIGE
MSMEG_5670|M.smegmatis_MC2_155      GLIYLPIAIGALIFSPLSGRMVGRFGSRPSLVSAGVLITAATVMLAQMTA
MAV_1387|M.avium_104                ALLIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMS
TH_3965|M.thermoresistible__bu      ALLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGLTWLAVEMA
Mvan_4014|M.vanbaalenii_PYR-1       ALLTAPMAVATAVLAPVVGRIVDRAHPRPVVGFGFGLLTAGLIWLAVEMT
MAB_1396|M.abscessus_ATCC_1997      ALTQAPTAIVSGILAPLAGWLVDRVRPSILIGGGIALMIASTLWWTLLMR
Mb3755|M.bovis_AF2122/97            GMAVAPAALVAAVVAAVLGRVADRHGYRFIVGIGALIWAASLLWYLKVVG
Rv3728|M.tuberculosis_H37Rv         GMAVAPAALVAAVVAAVLGRVADRHGYRFIVGIGALIWAASLLWYLKVVG
MMAR_2964|M.marinum_M               GLAVCPAAIIAAVTAGLLGRVADRHGYRVIIGVGALIWAGSLLWYLTCVG
MUL_3590|M.ulcerans_Agy99           GFAIAPAALIAAVVAAVLGRIADQRGHRLVVMAGAIIWAGSLVWYLQRVG
MLBr_01562|M.leprae_Br4923          GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMN
                                    .    * .:   :     . : .:         .  :   .         

Mflv_0301|M.gilvum_PYR-GCK          DASWVFDVAPA-ALVFGAGMVLVVAPLTATVLDAAP-EHMAGSASGVNNA
MSMEG_5670|M.smegmatis_MC2_155      TTP-VWLLLVI-FAVFGIGFALVNAPITTAAVSGMP-LDRAGAASAVAST
MAV_1387|M.avium_104                PATPIWRLVLP-FFAMGVGMAFVWSPLTATATRNLS-AQLAGAGSAVYNS
TH_3965|M.thermoresistible__bu      PTTPIWRLVLP-FVAVGVGMAFIWSPLATTATRQLP-LHLSGAGSGVYNT
Mvan_4014|M.vanbaalenii_PYR-1       PDTPAWRLALP-LTMVGAAGAFTWEPLSAIATRGLT-SELAGAGSAVCNT
MAB_1396|M.abscessus_ATCC_1997      PETQMWQLMLP-AAGIGAAMACIWGPLATTATRNLP-PSVAGAGSGVYNT
Mb3755|M.bovis_AF2122/97            SQPDFLGEWLPGQILQGIGVGATFPLLGSAALARLAKGGSYATASAVTGT
Rv3728|M.tuberculosis_H37Rv         SQPDFLGEWLPGQILQGIGVGATFPLLGSAALARLAKGGSYATASAVTGT
MMAR_2964|M.marinum_M               TTPNFLGEWLPGQILQGIGVGAAFPLLGSAALAGLASGSSYATASAVTGT
MUL_3590|M.ulcerans_Agy99           TEPNFLREWLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASAVVST
MLBr_01562|M.leprae_Br4923          RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVG-FDRIGPVSAIALM
                                                    * .       :   .          .. *.:   

Mflv_0301|M.gilvum_PYR-GCK          VARAGGLLAVAVLPGVAGISGNDYAD--P---------------------
MSMEG_5670|M.smegmatis_MC2_155      SRQVGVSIGVALCGSVAGTALAGTG-------------------------
MAV_1387|M.avium_104                VRQLGAVLGSAGMAAFMTWRIGAEMPGQP---------------------
TH_3965|M.thermoresistible__bu      TRQIGSVLGSAGMAAFLTGRLSAELPFGA---------------------
Mvan_4014|M.vanbaalenii_PYR-1       ARHVGAALSSAGIAALMAVLLGDEHAEEA---------------------
MAB_1396|M.abscessus_ATCC_1997      LRQVGGVVGSSAMGALMTARLTATMPAMP---------------------
Mb3755|M.bovis_AF2122/97            IRQVGAVIGVAVLVILVGTPAPGAAEEALRHRWALAAICFVAVGIGALSL
Rv3728|M.tuberculosis_H37Rv         IRQVGAVIGVAVLVILVGTPAPGAAEEALRHGWALAAICFVAVGIGALSL
MMAR_2964|M.marinum_M               IRQVGAVIGVALLVILVGTPAPGAAEESLRRGWTMAAICFVAVALGAVWL
MUL_3590|M.ulcerans_Agy99           TRQLGAVIGVALLVILIGKPAPGTGVEALRHGWVLAAVCFAAVAVLAGFL
MLBr_01562|M.leprae_Br4923          LQSLGGPLVLAVIQAVITSRTLYLGGTTG---------------------
                                        *  :  :    .                                  

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            GRIRPVPAAVEPPPGPPVAPLGARRPPRPAPVAS-PAAAVAPTPKTSREV
Rv3728|M.tuberculosis_H37Rv         GRIRPVPAAVEPPPGPPVAPLGARRPPRPAPVAS-PAAAVAPTPKTSREV
MMAR_2964|M.marinum_M               GRIRPAPAEAVTPESAP-----------PAQAPL-PQPSVAPVVSTSPDI
MUL_3590|M.ulcerans_Agy99           GRTQQGADVAGAPESGVAR-----APARPQPVTPRPAAAPARPPQTTADG
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            NLLEALR-----------FARPDTQQIELQAGSYLFHAGDVSDALYVVRS
Rv3728|M.tuberculosis_H37Rv         NLLEALR-----------FARPDTQQIELQAGSYLFHAGDVSDALYVVRS
MMAR_2964|M.marinum_M               DVLQAVP-----------DLHRHAEHVELQAGSYLFRAGDVSDSLYVVRS
MUL_3590|M.ulcerans_Agy99           DLLRQLPLFAGLPAATMAELRHHTDEIELQAGSYLFHEVDPSDALYVVRS
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          -------------------AAFSAGFHTAVVISAVLMVAAAVLAAIGIRR
MSMEG_5670|M.smegmatis_MC2_155      -------------------VDFAAASRPLWLICTALGVVIVAIGIVSTSP
MAV_1387|M.avium_104                -------------------GGGGEDSAGPVLPEFLRGPFAAAMSQSVLLP
TH_3965|M.thermoresistible__bu      -------------------TAVPAGEQTRVLPEFLHAPYAAAMAQSMLLP
Mvan_4014|M.vanbaalenii_PYR-1       -------------------GARHETLAP--LVDSLKDPFAGAMAQSMLLP
MAB_1396|M.abscessus_ATCC_1997      -------------------PGSG-STPEAALPPGLRAPFSAAMAQSMLLG
Mb3755|M.bovis_AF2122/97            GRLQVLAGDGAKDEVVAELGRGQVVGELGVLLDAPRSASVRAVRDSSLMR
Rv3728|M.tuberculosis_H37Rv         GRLQVLAGDGAKDEVVAELGRGQVVGELGVLLDAPRSASVRAVRDSSLMR
MMAR_2964|M.marinum_M               GRLQVIDEHG----LVAELGRGQLVGEVGVLRDAPRSASVLAVRDSSLLR
MUL_3590|M.ulcerans_Agy99           GRLRVVQRDL----VLRELGRGEVVGELGLLIDAPRSASVQAMRDFVLIR
MLBr_01562|M.leprae_Br4923          ------------------PVKFMNDAQLRALDHGYTYGLLWVAGAVVIVG
                                                                  :          .        

Mflv_0301|M.gilvum_PYR-GCK          APARSDERMAVENCTHCA--------------------------------
MSMEG_5670|M.smegmatis_MC2_155      WALRSAERLAPLIGQHHR--------------------------------
MAV_1387|M.avium_104                AFIALFGIVAALFLVGFRPWAHRDGGTDAFGPDDYGGDYHDDYDDDDAYV
TH_3965|M.thermoresistible__bu      AFVALFGVLAAIFLAGIVLSTPQP---------DADAQYLDEHDD---YL
Mvan_4014|M.vanbaalenii_PYR-1       AAAAAMGVLTALFLVG----------------------------------
MAB_1396|M.abscessus_ATCC_1997      IAALALGLVAALFMRP----------------------------------
Mb3755|M.bovis_AF2122/97            VTKAEFAKIADAGVLGALAGVLAKRQHQT--RVASQRTTPEVVVAVVGVD
Rv3728|M.tuberculosis_H37Rv         VTKAEFAKIADAGVLGALAGVLAKRQHQT--RVASQRTTPEVVVAVVGVD
MMAR_2964|M.marinum_M               VPKSEFAKIADARLLGVLASVLANRQVPTS-RTASRPPTREVVVAVIGVD
MUL_3590|M.ulcerans_Agy99           LSKAQFNRIADRGVLAALVGTLATRLHTAPPPTVDRPASPEAVIAVIGLG
MLBr_01562|M.leprae_Br4923          VAALFIGYTPEQVAYA----------------------------------
                                             .                                        

Mflv_0301|M.gilvum_PYR-GCK          ----------------------------ITGLPAHPAAETR---------
MSMEG_5670|M.smegmatis_MC2_155      ----------------------------PAEVAHAR--------------
MAV_1387|M.avium_104                ELILVREPEPEAQQRAGQPRRPQPTPAPPADVRRRDPVESRRSVLDERPA
TH_3965|M.thermoresistible__bu      VIELAR-----------------PDPNPRTDIAVTAVIPALRPTLRP---
Mvan_4014|M.vanbaalenii_PYR-1       -----------------------------GDATARAAPLSLR--------
MAB_1396|M.abscessus_ATCC_1997      -----------------------------GGSQVGAVP------------
Mb3755|M.bovis_AF2122/97            ANAPVAMVATELCRALSTRLRAVAPGRVDCDGLERAEQTADRVVLHAAVG
Rv3728|M.tuberculosis_H37Rv         ANAPVAMVATELCRALSTRLRAVAPGRVDCDGLERAEQTADRVVLHAAVG
MMAR_2964|M.marinum_M               AGAPATVVATELCAALSQRLRAVAPGRVNADGLERAERSADRVVLQATVG
MUL_3590|M.ulcerans_Agy99           AAVPVRPVALALLNALSARVTAVDPGRVDRAGLERAEASADKVVLDASAN
MLBr_01562|M.leprae_Br4923          -----------------------------QEVKEAVDAGEL---------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                QVQPIGFAHNGSHVDGGKRLRQVAVRRAPKPGPPADRFTRPPRRHHPGPA
TH_3965|M.thermoresistible__bu      -----------------------TLR--PSLGPPGGPVVQP---------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------PWGDASVSS---------
MAB_1396|M.abscessus_ATCC_1997      ----------------------------------LDDVVSVED-------
Mb3755|M.bovis_AF2122/97            DARWREFCLRVADRVVLVASNPAVPVAPLPTRATGADLVLAGRPAGREHR
Rv3728|M.tuberculosis_H37Rv         DARWREFCLRVADRVVLVASNPAVPVAPLPTRATGADLVLAGRPAGREHR
MMAR_2964|M.marinum_M               DGPWLDFCVRVADRVVLVARDFLAPPRRLTAKAPGVDLVLTGPSAAPVYR
MUL_3590|M.ulcerans_Agy99           DTGWRDFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDR
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                GHHLGEGESLRGQHHRPDPDDDPTGYGRHSSGN-----------------
TH_3965|M.thermoresistible__bu      ----NNTAALR---------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            RAWEQLITPRSMHVVRREFVADDLRVLATRIAGRSVGLVLSGGAARACAH
Rv3728|M.tuberculosis_H37Rv         RAWEQLITPRSMHVVRREFVADDLRVLATRIAGRSVGLVLSGGAARACAH
MMAR_2964|M.marinum_M               REWEELITPRSVHTVHPATIADDLRPLAARIAGRSVGLVLGGGGALACAH
MUL_3590|M.ulcerans_Agy99           SRWEELIPPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAH
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            LGVLEELEAAGVTVDRFAGTSMGAIIAALAASGLDAAGVDAQIYEHFVRK
Rv3728|M.tuberculosis_H37Rv         LGVLEELEAAGVTVDRFAGTSMGAIIAALAASGLDAAGVDAQIYEHFVRK
MMAR_2964|M.marinum_M               LGVLEELEAAGITVDRYAGTSMGALMAALAADGVDAAGVDAYIYEYFVRK
MUL_3590|M.ulcerans_Agy99           LGVLDELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRH
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            S-HGDYTLPSKGLIRGKRTQSTLRTIFGDHLVEELPKHFRCVSVDLLARR
Rv3728|M.tuberculosis_H37Rv         S-HGDYTLPSKGLIRGKRTQSTLRTIFGDHLVEELPKHFRCVSVDLLARR
MMAR_2964|M.marinum_M               N-HSDFTLPSKGFLRGKRTEVALRSAFGDRLVEELPKQFRCVSVDLLARQ
MUL_3590|M.ulcerans_Agy99           NPLGDYTLPSKGLVRGRRTMGLLREAYSGRMVEELPKEFRCVSVDLLARQ
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            PVVHRQGPLADVVGCSMRLPFLYAPLPYGGTLHVDGGVLDNVPVTTLVGK
Rv3728|M.tuberculosis_H37Rv         PVVHRQGPLADVVGCSMRLPFLYAPLPYGGTLHVDGGVLDNVPVTTLVGK
MMAR_2964|M.marinum_M               SVVHRSGLLTDVISCSMRLPVMYPPMAHAGSLHVDGGILDNVPVTALAGP
MUL_3590|M.ulcerans_Agy99           AVVHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            DGPLIAVNVASGGNPSPASGGHRRGKPRVPGLTDTLLRTMTISSAMASEK
Rv3728|M.tuberculosis_H37Rv         DGPLIAVNVASGGNPSPASGGHRRGKPRVPGLTDTLLRTMTISSAMASEK
MMAR_2964|M.marinum_M               EGPVIAVNVA-GGNRDSAPDSRHGKRLQVPGITDTLLRALTIGSAMTSSE
MUL_3590|M.ulcerans_Agy99           EGPMIAVSVGFGGNPSGGQ-PRRSGPIQVPGIGDTLMRTMMMGSRTVADA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5670|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4014|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1396|M.abscessus_ATCC_1997      --------------------------------------------------
Mb3755|M.bovis_AF2122/97            VLAQADLVIKPNPIGVGLMEYHQIDRAREAGRIAAREALPQIMELVHG--
Rv3728|M.tuberculosis_H37Rv         VLAQADLVIKPNPIGVGLMEYHQIDRAREAGRIAAREALPQIMELVHG--
MMAR_2964|M.marinum_M               VLAHADVVIQPNPSGIGFLEFHQIDRAREAGRMAARQALPQIMKLVFP--
MUL_3590|M.ulcerans_Agy99           AQAEALVVIRPDTRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGP
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0301|M.gilvum_PYR-GCK          ------------------------
MSMEG_5670|M.smegmatis_MC2_155      ------------------------
MAV_1387|M.avium_104                ------------------------
TH_3965|M.thermoresistible__bu      ------------------------
Mvan_4014|M.vanbaalenii_PYR-1       ------------------------
MAB_1396|M.abscessus_ATCC_1997      ------------------------
Mb3755|M.bovis_AF2122/97            ------------------------
Rv3728|M.tuberculosis_H37Rv         ------------------------
MMAR_2964|M.marinum_M               ------------------------
MUL_3590|M.ulcerans_Agy99           AGQTTGRAIDRSARALRTDARRPA
MLBr_01562|M.leprae_Br4923          ------------------------