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AFVFATPELVSAAAQDVANIGTSLGAANAAVAAPTTSVLAAGGDEVSHAIATMLRNHGAQYQALSAQGAQ VHQRIVQLLNSASGAYASAEAANASPLQTLESTVLDAVNTPTQALFGRPLIGNGANGTATSPNGGAGGIL YGNGGNGYSFTSGGLQNGGSGGSAGLIGNGGNGGNGFLGGTGGAGGSGGWLAGSGGNGGAGGSVSGIGEI AGAGGAGGNAPLLGWGGNGGVGGNAPQGTGGIGGAGGAGGALSAVGGTGGTGGSGGVAGGDGGAGGAGRG LFYGLGGAGGMGGSATAVTPHTGGTGGVGGEGGAVFGYAQGGTGGIGGFANDTGGLGGQGGDATALLGVG VGGAGSIGGAGNAAASAGGAGGAGAALVGVGVGGIGGIGGFANGTSGAGGAGGSGAAVMGLGVGGAGSIG GAANSTAGAGGDGGEGVALVGVGVGGAGSIGGFANDFGGAGGQGGQGAVLIGAGFGGAGGDGGSATVNAV GNGGDGGNAGALFGIGAGGHGGNAGSGVGAANGGNGGSVGVISDGSFTPTPVGYGGNGGNGVNGGTGGTG GTGGTLIGTDGTNGSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2112 | - | - | 100% (577) | PE-PGRS family protein |
| M. marinum M | MMAR_2113 | - | 0.0 | 63.31% (586) | PE-PGRS family protein |
| M. marinum M | MMAR_2970 | - | e-149 | 49.28% (621) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2622 | PE_PGRS44 | 1e-175 | 57.37% (563) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-89 | 45.71% (466) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2591 | PE_PGRS44 | 1e-175 | 57.55% (563) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 9e-14 | 39.58% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-44 | 33.55% (462) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-20 | 39.77% (176) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-67 | 35.27% (601) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 6e-35 | 36.31% (314) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1718 | - | 0.0 | 64.60% (500) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-89 | 45.67% (462) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2112|M.marinum_M --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2112|M.marinum_M --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2112|M.marinum_M --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2112|M.marinum_M --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_2112|M.marinum_M --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAALAN----------------AGLSAVSAAQVGAVMPVVAESVASNYGY
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDA
MMAR_2112|M.marinum_M ----------------MAFVFATPELVSAAAQDVANIGT-----------
MUL_1718|M.ulcerans_Agy99 ----------------MAFVIAAPELVSAAAENVASIGT-----------
Mb2622|M.bovis_AF2122/97 ----------------MSFVTAAPEMLATAAQNVANIGT-----------
Rv2591|M.tuberculosis_H37Rv ----------------MSFVTAAPEMLATAAQNVANIGT-----------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
MAB_4284c|M.abscessus_ATCC_199 QSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSP--RDNDFLSHN
MLBr_01183|M.leprae_Br4923 ---------------MPLFLNAEPQALTAAANTLEGLSA-----------
MAV_4827|M.avium_104 IDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAA
.
MMAR_2112|M.marinum_M SLGAANAAVAAPTTSVLAAGGDEVSHAIATMLRNHGAQYQALSAQGAQVH
MUL_1718|M.ulcerans_Agy99 SLGAANAAVAASTTSVLSAGADDVSQAFAALLSSHGAQYQALSAQAAQFH
Mb2622|M.bovis_AF2122/97 SLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFH
Rv2591|M.tuberculosis_H37Rv SLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFH
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR---------TTDNNALDGG
MAB_4284c|M.abscessus_ATCC_199 DTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG
MLBr_01183|M.leprae_Br4923 ATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNH
MAV_4827|M.avium_104 ALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTAT
. :
MMAR_2112|M.marinum_M QRIVQLLNSASGAYASAEAANASPLQTLESTVLDAVN-------------
MUL_1718|M.ulcerans_Agy99 QGLMQLLNSAGGAYAGAEAANVSPLQTLESNVVGALN-------------
Mb2622|M.bovis_AF2122/97 HSFVQTLNAAGGAYSSAEAANAS-AQALEQNLLAVIN-------------
Rv2591|M.tuberculosis_H37Rv HSFVQTLNAAGGAYSSAEAANAS-AQALEQNLLAVIN-------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu HGGNGGNVG-----FFSLFNLGGAGGWGGSGVDG----------------
MAB_4284c|M.abscessus_ATCC_199 DGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHG----------SN
MLBr_01183|M.leprae_Br4923 QDLIQSLLTSSSAYAGTETANHDSL-------------------------
MAV_4827|M.avium_104 LAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG-------------
MMAR_2112|M.marinum_M ---TPTQALFGRPLIGNGANGTATSPNGGAGGILYG--------------
MUL_1718|M.ulcerans_Agy99 ---TPTQAIFGRPLIGDGANGTATSPNGGAGGFLYG--------------
Mb2622|M.bovis_AF2122/97 ---APAQALFGRPLIGNGANGTAASPNGGDGGILYG--------------
Rv2591|M.tuberculosis_H37Rv ---APAQALFGRPLIGNGANGTAASPNGGDGGILYG--------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --VDVVGGNPDGGTPGAHG--ESHTPGVYTDR------------------
MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVS------------
MMAR_2112|M.marinum_M --------------------------------------------NGGNGY
MUL_1718|M.ulcerans_Agy99 --------------------------------------------NGGNGY
Mb2622|M.bovis_AF2122/97 --------------------------------------------NGGNGF
Rv2591|M.tuberculosis_H37Rv --------------------------------------------NGGNGF
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------QGEDGE
MAB_4284c|M.abscessus_ATCC_199 -----------------------QRNTTN---------------INDSFN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------VAEEPE
MMAR_2112|M.marinum_M SFTSGGLQNGGSGG------------------------------------
MUL_1718|M.ulcerans_Agy99 SFTSGGTQSGGTGG------------------------------------
Mb2622|M.bovis_AF2122/97 SQTTAGVA-GGAGG------------------------------------
Rv2591|M.tuberculosis_H37Rv SQTTAGVA-GGAGG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu DGTGTGIGGRGGNG------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TDRSTNIGSGNTTN------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TALARGAALAAANAP-----------------------------------
MMAR_2112|M.marinum_M -----SAGLIGNGGNGGNGFLGGTGGAGGSG-------------------
MUL_1718|M.ulcerans_Agy99 -----SAGLIGNGGNGGNGFLGGAGGAAGSG-------------------
Mb2622|M.bovis_AF2122/97 -----SAGLIGNGGNGGAGGAGAAGGAGGAG-------------------
Rv2591|M.tuberculosis_H37Rv -----SAGLIGNGGNGGAGGAGAAGGAGGAG-------------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu ------------------GSSSGTHPMAEDG-------------------
MAB_4284c|M.abscessus_ATCC_199 ----TEIGSHNQANIGTSTSAGGSAAVGGNAG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------LFASSTAALAYAQDPGTGAVDQYS-------------------
MMAR_2112|M.marinum_M ------GWLAGSGGNGGAGGS------------------------VSGIG
MUL_1718|M.ulcerans_Agy99 ------GWLAGSGGNGGAGGS------------------------VTGVG
Mb2622|M.bovis_AF2122/97 ------GWLLGNGGAGGPGGP------------------------TDVPA
Rv2591|M.tuberculosis_H37Rv ------GWLLGNGGAGGPGGP------------------------TDVPA
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu -----EHVKALDGRPGLDGG----------------------------NG
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAGNAG-----------------LAGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----LPDYLYVPVDPEPGDDE----------------------LAYSAVG
MMAR_2112|M.marinum_M EIAGAGGAGGNAPLLG----------------------------------
MUL_1718|M.ulcerans_Agy99 EVGGAGGAGGSAPLLG----------------------------------
Mb2622|M.bovis_AF2122/97 GTGGAGGAGGDAPLIG----------------------------------
Rv2591|M.tuberculosis_H37Rv GTGGAGGAGGDAPLIG----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu SHGGNGGHGGRGGFLG----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EEDAESPTVVIEKLFLP---------------------------------
MMAR_2112|M.marinum_M ------------WGGNGGVGGNAPQGTGGIGGAGGAGGA-----------
MUL_1718|M.ulcerans_Agy99 ------------WGGNGGAGGDSTQGTGGRGGAGGAGGA-----------
Mb2622|M.bovis_AF2122/97 ------------WGGNGGPGGFAAFGNGGAGGNGGASGS-----------
Rv2591|M.tuberculosis_H37Rv ------------WGGNGGPGGFAAFGNGGAGGNGGASGS-----------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGA--GGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGN--GGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGF--NGTGGATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu ------------IGGSGGWGGH--GGNGGDTDADG---------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGL--AGNAGLAGNAGLAGN-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------EDSEPRRRPVLLVGSGLAVVGISAVLA-----------
MMAR_2112|M.marinum_M -------------------------------------LSAVGGTGGTGGS
MUL_1718|M.ulcerans_Agy99 -------------------------------------LAAIGGAGGAGGT
Mb2622|M.bovis_AF2122/97 -------------------------------------LFGVGGAGGVGGS
Rv2591|M.tuberculosis_H37Rv -------------------------------------LFGVGGAGGVGGS
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu ---------------------------------------GNGGDGGNGGS
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------AGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------LEIALAIGIRTTGTVALQ
MMAR_2112|M.marinum_M GGVAGGDGGAGGAGRGL----------------------------FYGLG
MUL_1718|M.ulcerans_Agy99 GATAGGDGGVGGEGSGR----------------------------LFGLG
Mb2622|M.bovis_AF2122/97 SEDVGGTGGAGGAGRGL----------------------------FLGLG
Rv2591|M.tuberculosis_H37Rv SEDVGGTGGAGGAGRGL----------------------------FLGLG
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG
TH_3810|M.thermoresistible__bu AGRGGTGGLRGVFGIN---------------------------------G
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAG---------------------------NAGLAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PTPNQHLIVPTEQAPAP--------------------------PPVQASA
MMAR_2112|M.marinum_M GAGGMG---------------------------GSATAVT----------
MUL_1718|M.ulcerans_Agy99 GAGGAG---------------------------GTGTTS-----------
Mb2622|M.bovis_AF2122/97 GDGGAG---------------------------GTSNNN-----------
Rv2591|M.tuberculosis_H37Rv GDGGAG---------------------------GTSNNN-----------
Mflv_5091|M.gilvum_PYR-GCK GTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG------
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRA
TH_3810|M.thermoresistible__bu GNGRAG-----------------------------LGGRGXXXX------
MAB_4284c|M.abscessus_ATCC_199 NAGLAG--------------------------NAGLAGNAGLAG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PQPKIS-------------------------VPEPVAAPKPLSPP-----
MMAR_2112|M.marinum_M ------PHTGGTGGVGGEGGAVFGYAQGGT--------------------
MUL_1718|M.ulcerans_Agy99 ------------GGVGG---------------------------------
Mb2622|M.bovis_AF2122/97 ---------GGDGGAGGTAGGRLFSLGGD---------------------
Rv2591|M.tuberculosis_H37Rv ---------GGDGGAGGTAGGRLFSLGGD---------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGGQGG-LGGGGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------TGGTGGQGG-LGGVGGTG---------------------
MSMEG_0868|M.smegmatis_MC2_155 TVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTA
TH_3810|M.thermoresistible__bu -----------GGGVG----------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------NAAVAGNAAVAGNAAVAG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------VAAPLPAAPPPAAPPLPEAPPIP---------------------
MMAR_2112|M.marinum_M ---GGIGGFANDTGGLGGQGGDATAL--------LGVGVGGAGSIGGAGN
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
Mb2622|M.bovis_AF2122/97 ---------------------------------------GGNGGAGTAIG
Rv2591|M.tuberculosis_H37Rv ---------------------------------------GGNGGAGTAIG
Mflv_5091|M.gilvum_PYR-GCK --GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGG
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGG
MSMEG_0868|M.smegmatis_MC2_155 TDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGG
TH_3810|M.thermoresistible__bu -----------------------------------AAVRSGNGVFSGGGG
MAB_4284c|M.abscessus_ATCC_199 ---NAAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------------AAPPVVPVPVVVPPVPV
MMAR_2112|M.marinum_M AAASAGGAGGAGAALVGVGVGGIGGIGG---------------------F
MUL_1718|M.ulcerans_Agy99 ----TGGAGGVAGVLVGAGVGGFGGMG-----------------------
Mb2622|M.bovis_AF2122/97 SNAGDGGAGGDSSALIGYAQGGSGGLGG---------------------F
Rv2591|M.tuberculosis_H37Rv SNAGDGGAGGDSSALIGYAQGGSGGLGG---------------------F
Mflv_5091|M.gilvum_PYR-GCK FGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGS
Mvan_1264|M.vanbaalenii_PYR-1 FGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGS
MSMEG_0868|M.smegmatis_MC2_155 NGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGY
TH_3810|M.thermoresistible__bu TPSAGFGVPTTIQFPAGSCTSRAVSREG----------------------
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------GI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVPVRIPVPDPVSPPQLLAPPRLSVPQP-------------------VQP
MMAR_2112|M.marinum_M ANGTSGAGGAGGSGAAVMGLGVGGAGSIG--------GAANSTAGAGGDG
MUL_1718|M.ulcerans_Agy99 -----GAG---------------------------------TTGGAGDVG
Mb2622|M.bovis_AF2122/97 GESTGGDGGLGGAGAVLIGTGVGGFGGLG--------GGSNGTGGAGGAG
Rv2591|M.tuberculosis_H37Rv GESTGGDGGLGGAGAVLIGTGVGGFGGLG--------GGSNGTGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 AGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQ
MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATG
TH_3810|M.thermoresistible__bu --IMPSSRAASARAG---------------------------AACASSTS
MAB_4284c|M.abscessus_ATCC_199 SESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PVRVPQPPSPPQVGGTVPQSPPQHQTPPG-------EGTPPKPDGPGNYG
MMAR_2112|M.marinum_M GEGVALVGVGVGGAGS-----------IGGFANDFG----GAGGQGGQGA
MUL_1718|M.ulcerans_Agy99 GQGVTLTGLGVGGIGG-----------VGGFGTATG----GDGGAGGQGA
Mb2622|M.bovis_AF2122/97 GTGATLIGLGAGGGGS-----------IGGFAVNVGNGVGGLGGQGGQGA
Rv2591|M.tuberculosis_H37Rv GTGATLIGLGAGGGGG-----------IGGFAVNVGNGVGGLGGQGGQGA
Mflv_5091|M.gilvum_PYR-GCK GATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGA
MSMEG_0868|M.smegmatis_MC2_155 GDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGA
TH_3810|M.thermoresistible__bu RSRRSFCCSRA---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGHVPTPGAGGSGGSG-------------GGHVPTPGAGGSGGSGGGHVP
MMAR_2112|M.marinum_M VLIGAGFGGAGGDGGSATVNAVGNGGDGGNAGALFGIGAGGHGG------
MUL_1718|M.ulcerans_Agy99 ALWGAGFGGDGAVGGNSFVGAGGNGGDGGNGGGLFNIGRGGDGG------
Mb2622|M.bovis_AF2122/97 ALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGDGG------
Rv2591|M.tuberculosis_H37Rv ALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGGLFSIGVGGDGG------
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG---
Mvan_1264|M.vanbaalenii_PYR-1 AGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG---
MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TPGTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPG------
MMAR_2112|M.marinum_M ---------NAGSGVGAANGGNGGSVGVISDGSFTPTPVGYGGNGGNGVN
MUL_1718|M.ulcerans_Agy99 ---------NGGN--AGATGGNGGNIGVVANGTFTQTLFGDGGNGGNGGN
Mb2622|M.bovis_AF2122/97 ---------NAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVN
Rv2591|M.tuberculosis_H37Rv ---------NAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVN
Mflv_5091|M.gilvum_PYR-GCK --------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTG
MSMEG_0868|M.smegmatis_MC2_155 VWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------GSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGHA
MMAR_2112|M.marinum_M GGTG---GTGGTGGTLIGTDGTNGSP-----
MUL_1718|M.ulcerans_Agy99 GGTGGTPGTGGSGGILIGADGTNGS------
Mb2622|M.bovis_AF2122/97 GGTG---GTGGSGGILFGANGANGPS-----
Rv2591|M.tuberculosis_H37Rv G------GTGGSGGILFGANGANGPS-----
Mflv_5091|M.gilvum_PYR-GCK GAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu -------------------------------
MAB_4284c|M.abscessus_ATCC_199 GTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 -------------------------------
MAV_4827|M.avium_104 PAPGGGLGGFGGGHSGGGLGGLGGGHK----