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VRLHVRGRGLPDETAVELWIVDGHISTEPVSGADTVFDGGWILPGLVDAHCHVGLGHQGAIELDQAIAQA EAERDAGALLLRDCGAPTDTRPLDDREDLPRIIRAGRHLARPKRYIPGFAAELEDESELPAAVAAQARRG DGWIKLVGDWIDRQIGDLAPLWSDEVLKAAIDAAHANGARVTAHVFGEDALPGLINAGIDCIEHGTGLTD DTISLMRDHGTALVPTLINVENFPGIADSAVRYPTYAAHMRDLYASTYPRVAAAREAGIAIYAGTDAGGT IQHGRIADEVEALKKIGMSATEALGAACWEARRWLGRPTVEHGASADLVCFSEDPRRGAAILNRPDLVIL RGRTYRPNQLGHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1793 | - | - | 100% (363) | hypothetical protein MMAR_1793 |
| M. marinum M | MMAR_4746 | - | 2e-23 | 29.41% (357) | imidazolonepropionase |
| M. marinum M | MMAR_0954 | - | 4e-11 | 23.80% (374) | imidazolonepropionase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2939c | - | 1e-178 | 82.91% (357) | hypothetical protein Mb2939c |
| M. gilvum PYR-GCK | Mflv_4181 | - | 1e-156 | 75.35% (357) | amidohydrolase |
| M. tuberculosis H37Rv | Rv2915c | - | 1e-178 | 82.91% (357) | hypothetical protein Rv2915c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3236c | - | 1e-153 | 71.67% (353) | amidohydrolase |
| M. avium 104 | MAV_3769 | - | 1e-164 | 76.94% (360) | amidohydrolase 3 |
| M. smegmatis MC2 155 | MSMEG_2431 | - | 1e-161 | 76.47% (357) | amidohydrolase 3 |
| M. thermoresistible (build 8) | TH_2394 | - | 1e-164 | 76.26% (358) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2041 | - | 0.0 | 99.45% (363) | hypothetical protein MUL_2041 |
| M. vanbaalenii PYR-1 | Mvan_2182 | - | 1e-154 | 73.37% (353) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4181|M.gilvum_PYR-GCK ----------MDGTPLHVRGRRLPDGEPVEWWIVGGRLSADPVAGAETVF
Mvan_2182|M.vanbaalenii_PYR-1 --------MTADRTPLHIRGRSLPDGEPDEWWIVHGRLSAEPVAGAETVF
MSMEG_2431|M.smegmatis_MC2_155 ------------MSALHVRGRGLPDGEPVEWWIADGVLSAEPIAGADTVF
TH_2394|M.thermoresistible__bu ------------VKALHLRGRGLPHEQPVEWWIVDGRLSAEPVAGAETIF
MAB_3236c|M.abscessus_ATCC_199 -------------MRAHLRGRTLPSEEPIDLWVHDGVISIEPIADADTVF
MMAR_1793|M.marinum_M -------------MRLHVRGRGLPDETAVELWIVDGHISTEPVSGADTVF
MUL_2041|M.ulcerans_Agy99 -------------MRLHVRGRGLPDETAVELWIVDGHISAEPVSGADTVF
Mb2939c|M.bovis_AF2122/97 MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAGADTVF
Rv2915c|M.tuberculosis_H37Rv MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAGADTVF
MAV_3769|M.avium_104 -------------MRWHLRGRSLPDEGPIELWVVDGRISTQPVAGADTVF
*:** ** . : *: * :* :*::.*:*:*
Mflv_4181|M.gilvum_PYR-GCK GADGDGGWVLPGLVDAHCHVGLGPGGPTGLDEAIGQAETEREVGALLLRD
Mvan_2182|M.vanbaalenii_PYR-1 ----DGGWILPGLVDAHCHVGLGPHGAIGMDEAVAQAETERGVGALLLRD
MSMEG_2431|M.smegmatis_MC2_155 GAGGELGWIIPGLVDAHCHVGLGPGGAVGIDEAVAQAETERDAGALLLRD
TH_2394|M.thermoresistible__bu GRHGYDGWILPGLVDAHCHVGIGPGGAVEFDEAIAQAETERDVGALLLRD
MAB_3236c|M.abscessus_ATCC_199 ----DGGWLLPGLVDAHCHVGIGPQGPTSLEEAVAQAEAEREVGALLLRD
MMAR_1793|M.marinum_M ----DGGWILPGLVDAHCHVGLGHQGAIELDQAIAQAEAERDAGALLLRD
MUL_2041|M.ulcerans_Agy99 ----DGGWILPGLVDAHCHVGLGHQGAIELDQAIAQAEAERDAGALLLRD
Mb2939c|M.bovis_AF2122/97 ----DGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRD
Rv2915c|M.tuberculosis_H37Rv ----DGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRD
MAV_3769|M.avium_104 GA-SGGGWIVPGLVDAHCHVGLGEHGEIPLDEAIAQAEIERDVGALLLRD
**::***********:* * :::*:.*** ** .*******
Mflv_4181|M.gilvum_PYR-GCK AGSPVDTRSLDDRADLPRIIRAGRHLAKPKRYIPGLPIDIEDESQLPEYV
Mvan_2182|M.vanbaalenii_PYR-1 AGSPTDTRSFDDRPELPRIIRAGRHLARPRRYSRGFAVELEDEWQLPDAI
MSMEG_2431|M.smegmatis_MC2_155 AGSPLDTRSLDDREDLPRIIRAGRHLARPKRYLPGVPIDIEDESQLPAVV
TH_2394|M.thermoresistible__bu CGSPVDTRSLDERDDLPRIIRAGRHLARPKRYLPGLPIDIEDESQLPEYV
MAB_3236c|M.abscessus_ATCC_199 AGSPVDTRGFDEREDLPRIIRAGRHLAKPKRYIPGLPLDIEDDAQLPEAV
MMAR_1793|M.marinum_M CGAPTDTRPLDDREDLPRIIRAGRHLARPKRYIPGFAAELEDESELPAAV
MUL_2041|M.ulcerans_Agy99 CGAPTDTRPLDDREDLPRIIRAGRHLARPKRYIPGFAPELEDESELPAAV
Mb2939c|M.bovis_AF2122/97 CGSPTDTRGLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAV
Rv2915c|M.tuberculosis_H37Rv CGSPTDTRGLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAV
MAV_3769|M.avium_104 CGSPTDTRSLDDRDDLPRIIRAGKHLARPKRYAAGFSRELDDEWQLPDAV
.*:* *** :*:: :********:***:*:** *.. :::*: :** :
Mflv_4181|M.gilvum_PYR-GCK VQQARFGDGWVKLVGDWIDRGIGDLAPLWSDEVLEAAIAAAHANGARVTA
Mvan_2182|M.vanbaalenii_PYR-1 AQQARWGDGWVKLVGDWIDRDTGDLAPLWSDDVLEAAIDAAHANGARVTA
MSMEG_2431|M.smegmatis_MC2_155 AEQARWGDGWVKLIGDWIDRGAGDLAPLWSDDVLRAAIDAAHAEGARVTA
TH_2394|M.thermoresistible__bu AQQARWGDGWVKLVGDWIDRSIGDLAPLWSDEVLKEAVDAAHAHGARVTA
MAB_3236c|M.abscessus_ATCC_199 ALQARWGDGWVKLVGDWIDRAVGDLAPLWSDKILKQAIDAAHANGARVTA
MMAR_1793|M.marinum_M AAQARRGDGWIKLVGDWIDRQIGDLAPLWSDEVLKAAIDAAHANGARVTA
MUL_2041|M.ulcerans_Agy99 AAQARRGDGWIKLVGDWIDRQIGDLAPLWSDEVLKAAIDAAHANGARVTA
Mb2939c|M.bovis_AF2122/97 AEQARRGDGWVKLVGDWIDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTA
Rv2915c|M.tuberculosis_H37Rv AEQARRGDGWVKLVGDWIDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTA
MAV_3769|M.avium_104 AQEAKRGDGWIKLVGDWIDRSVGDLAPLWSDEVLKAAIDTAHAHGARVTA
. :*: ****:**:****** *********.:*. *: :***.******
Mflv_4181|M.gilvum_PYR-GCK HVFGEDALPGLIKAGIDCIEHGTGLTEDSIGLMVEYGTALVPTLIN-IEN
Mvan_2182|M.vanbaalenii_PYR-1 HVFSEDALPGLIKAGIDCIEHGTGLTEDTIDLMVQHGTALVPTLIN-IEN
MSMEG_2431|M.smegmatis_MC2_155 HVFGEDALPGLIGAGIDCIEHGTGLTDDTIASMVEHGTALVPTLIN-VET
TH_2394|M.thermoresistible__bu HVFGEDALPGLIKAGIDCIEHGTGLTDDTIELMVEHGTALVPTLIN-VEN
MAB_3236c|M.abscessus_ATCC_199 HVFGEDALPGLIHAGIDCIEHGTGLTDDTIALMVEHGTALVPTVIN-IEN
MMAR_1793|M.marinum_M HVFGEDALPGLINAGIDCIEHGTGLTDDTISLMRDHGTALVPTLIN-VEN
MUL_2041|M.ulcerans_Agy99 HVFGEDALPGLINAGIDCIEHGTGLTDDTISLMRDHGTALVPTLIN-VEN
Mb2939c|M.bovis_AF2122/97 HVFSEDALPGLINAGIDCIEHGTGLTDDTIALMLEHGTALVPTLIN-LEN
Rv2915c|M.tuberculosis_H37Rv HVFSEDALPGLINAGIDCIEHGTGLTDDTIALMLEHGTALVPTLIN-LEN
MAV_3769|M.avium_104 HVFSEDALPGLINAGIDCIEHGTGLTDDTIELMVSRGTALVPTLVNVVEN
***.******** *************:*:* * . *******::* :*.
Mflv_4181|M.gilvum_PYR-GCK FPGIAEAAGKYPTYARHMRDLYASCRDRVAAARDAGIPIFAGTDAGGMIA
Mvan_2182|M.vanbaalenii_PYR-1 FPDIAASADKYPAYQRHMRALYETCSARVGAAREAGVPIFAGSDAGSAVA
MSMEG_2431|M.smegmatis_MC2_155 FPGIADAAGKYPTYARHMRDLYASCYERVAAAHDAGVPIFAGTDAGGTIG
TH_2394|M.thermoresistible__bu FPSIADRAVRYPTYAAHMRDLHERSYAQVSAAREAGVPVYAGTDAGGMIA
MAB_3236c|M.abscessus_ATCC_199 FPGIADKAGKYPKYAQHMRDLYAGLHTTFGNAYDAGIPIYAGTDAGGSIA
MMAR_1793|M.marinum_M FPGIADSAVRYPTYAAHMRDLYASTYPRVAAAREAGIAIYAGTDAGGTIQ
MUL_2041|M.ulcerans_Agy99 FPGIADSAVRYPTYAAHMRDLYASTYPRVAAAREAGIAIYAGTDAGGTIQ
Mb2939c|M.bovis_AF2122/97 FPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAGVPVYAGTDAGSTIE
Rv2915c|M.tuberculosis_H37Rv FPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAGVPVYAGTDAGSTIE
MAV_3769|M.avium_104 FPGIAQAAAKYPTYAAHMRDLYARGPSRIAAAREAGVPIYAGSDAGTMVA
**.** * :** * *** *: .. * :**:.::**:*** :
Mflv_4181|M.gilvum_PYR-GCK HGRIADEVEALKGIGMTPTEALGAACWDAREWLRRPTLRHGASADLVCFT
Mvan_2182|M.vanbaalenii_PYR-1 HGRIAEEVDALKGIGMTPTEALGAACWDARAWLRRPGLAHGASADLVCFA
MSMEG_2431|M.smegmatis_MC2_155 HGRISDEVEALKRIGMTPTHALGAACWDARAWLGRPGLEHGASADLLCFD
TH_2394|M.thermoresistible__bu HGRIADEVEALKRIGMSSTEALGAASWNARSWLGRPGLEHGAPADLICYD
MAB_3236c|M.abscessus_ATCC_199 HGRISDEVAALTRIGMSPTDALGAASWRARSWLGRPGLEHGAPADLLGYR
MMAR_1793|M.marinum_M HGRIADEVEALKKIGMSATEALGAACWEARRWLGRPTVEHGASADLVCFS
MUL_2041|M.ulcerans_Agy99 HGRIADEVEALKKIGMSATEALGAACWEARRWLGRPTVEHGASADLVCFS
Mb2939c|M.bovis_AF2122/97 HGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASADLLCYA
Rv2915c|M.tuberculosis_H37Rv HGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASADLLCYA
MAV_3769|M.avium_104 PGRIADEVEALKGIGMTATQALGAACWDARRWLGRPGLEHGASADLLCFA
***::** ** ***:. .*****.* ** ** ** : . *.***: :
Mflv_4181|M.gilvum_PYR-GCK EDPLTGAEVLANPTRVILRGVVY--------
Mvan_2182|M.vanbaalenii_PYR-1 DDPRTGAGVLAHPTLVMLRGAAY--------
MSMEG_2431|M.smegmatis_MC2_155 EDPRVAG--ADHPDLVILRGRIF--------
TH_2394|M.thermoresistible__bu EDPRLGPEVLTRPSRVILRGRVFQRPRR---
MAB_3236c|M.abscessus_ATCC_199 ADPRTGPGVLASPDLVMLRGQIR--------
MMAR_1793|M.marinum_M EDPRRGAAILNRPDLVILRGRTYRPNQLGHR
MUL_2041|M.ulcerans_Agy99 EDPRRGAAILNRPDLVILRGRTYRPNQLGHR
Mb2939c|M.bovis_AF2122/97 QDPRQGPGVLQHPDLVILRGRTFGP------
Rv2915c|M.tuberculosis_H37Rv QDPRQGPGVLQHPDLVILRGRTFGP------
MAV_3769|M.avium_104 EDPRSGPAVLRNPDLIMLRGNIFRSPA----
** . * ::***