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M. thermoresistible (build 8) TH_2394 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 4676931 - 4678028
length: 366

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2394-100% (366)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_0262-7e-2331.61% (348) amidohydrolase
M. thermoresistible (build 8)TH_2020-1e-2227.90% (362) amidohydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2939c-1e-16176.47% (357) hypothetical protein Mb2939c
M. gilvum PYR-GCKMflv_4181-1e-16878.43% (357) amidohydrolase
M. tuberculosis H37RvRv2915c-1e-16176.47% (357) hypothetical protein Rv2915c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3236c-1e-15973.80% (355) amidohydrolase
M. marinum MMMAR_1793-1e-16376.26% (358) hypothetical protein MMAR_1793
M. avium 104MAV_3769-1e-16174.17% (360) amidohydrolase 3
M. smegmatis MC2 155MSMEG_2431-1e-17078.06% (360) amidohydrolase 3
M. ulcerans Agy99MUL_2041-1e-16476.54% (358) hypothetical protein MUL_2041
M. vanbaalenii PYR-1Mvan_2182-1e-15572.55% (357) amidohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4181|M.gilvum_PYR-GCK          ----------MDGTPLHVRGRRLPDGEPVEWWIVGGRLSADPVAGAETVF
Mvan_2182|M.vanbaalenii_PYR-1       --------MTADRTPLHIRGRSLPDGEPDEWWIVHGRLSAEPVAGAETVF
MSMEG_2431|M.smegmatis_MC2_155      ------------MSALHVRGRGLPDGEPVEWWIADGVLSAEPIAGADTVF
TH_2394|M.thermoresistible__bu      ------------VKALHLRGRGLPHEQPVEWWIVDGRLSAEPVAGAETIF
MAB_3236c|M.abscessus_ATCC_199      -------------MRAHLRGRTLPSEEPIDLWVHDGVISIEPIADADTVF
Mb2939c|M.bovis_AF2122/97           MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAGADTVF
Rv2915c|M.tuberculosis_H37Rv        MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAGADTVF
MMAR_1793|M.marinum_M               -------------MRLHVRGRGLPDETAVELWIVDGHISTEPVSGADTVF
MUL_2041|M.ulcerans_Agy99           -------------MRLHVRGRGLPDETAVELWIVDGHISAEPVSGADTVF
MAV_3769|M.avium_104                -------------MRWHLRGRSLPDEGPIELWVVDGRISTQPVAGADTVF
                                                    *:**  **   . : *:  * :* :*::.*:*:*

Mflv_4181|M.gilvum_PYR-GCK          GADGDGGWVLPGLVDAHCHVGLGPGGPTGLDEAIGQAETEREVGALLLRD
Mvan_2182|M.vanbaalenii_PYR-1       ----DGGWILPGLVDAHCHVGLGPHGAIGMDEAVAQAETERGVGALLLRD
MSMEG_2431|M.smegmatis_MC2_155      GAGGELGWIIPGLVDAHCHVGLGPGGAVGIDEAVAQAETERDAGALLLRD
TH_2394|M.thermoresistible__bu      GRHGYDGWILPGLVDAHCHVGIGPGGAVEFDEAIAQAETERDVGALLLRD
MAB_3236c|M.abscessus_ATCC_199      ----DGGWLLPGLVDAHCHVGIGPQGPTSLEEAVAQAEAEREVGALLLRD
Mb2939c|M.bovis_AF2122/97           ----DGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRD
Rv2915c|M.tuberculosis_H37Rv        ----DGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRD
MMAR_1793|M.marinum_M               ----DGGWILPGLVDAHCHVGLGHQGAIELDQAIAQAEAERDAGALLLRD
MUL_2041|M.ulcerans_Agy99           ----DGGWILPGLVDAHCHVGLGHQGAIELDQAIAQAEAERDAGALLLRD
MAV_3769|M.avium_104                GA-SGGGWIVPGLVDAHCHVGLGEHGEIPLDEAIAQAEIERDVGALLLRD
                                          **::***********:*  *   :::*:.*** ** .*******

Mflv_4181|M.gilvum_PYR-GCK          AGSPVDTRSLDDRADLPRIIRAGRHLAKPKRYIPGLPIDIEDESQLPEYV
Mvan_2182|M.vanbaalenii_PYR-1       AGSPTDTRSFDDRPELPRIIRAGRHLARPRRYSRGFAVELEDEWQLPDAI
MSMEG_2431|M.smegmatis_MC2_155      AGSPLDTRSLDDREDLPRIIRAGRHLARPKRYLPGVPIDIEDESQLPAVV
TH_2394|M.thermoresistible__bu      CGSPVDTRSLDERDDLPRIIRAGRHLARPKRYLPGLPIDIEDESQLPEYV
MAB_3236c|M.abscessus_ATCC_199      AGSPVDTRGFDEREDLPRIIRAGRHLAKPKRYIPGLPLDIEDDAQLPEAV
Mb2939c|M.bovis_AF2122/97           CGSPTDTRGLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAV
Rv2915c|M.tuberculosis_H37Rv        CGSPTDTRGLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAV
MMAR_1793|M.marinum_M               CGAPTDTRPLDDREDLPRIIRAGRHLARPKRYIPGFAAELEDESELPAAV
MUL_2041|M.ulcerans_Agy99           CGAPTDTRPLDDREDLPRIIRAGRHLARPKRYIPGFAPELEDESELPAAV
MAV_3769|M.avium_104                CGSPTDTRSLDDRDDLPRIIRAGKHLARPKRYAAGFSRELDDEWQLPDAV
                                    .*:* *** :*:: :********:***:*:**  *.. :::*: :**  :

Mflv_4181|M.gilvum_PYR-GCK          VQQARFGDGWVKLVGDWIDRGIGDLAPLWSDEVLEAAIAAAHANGARVTA
Mvan_2182|M.vanbaalenii_PYR-1       AQQARWGDGWVKLVGDWIDRDTGDLAPLWSDDVLEAAIDAAHANGARVTA
MSMEG_2431|M.smegmatis_MC2_155      AEQARWGDGWVKLIGDWIDRGAGDLAPLWSDDVLRAAIDAAHAEGARVTA
TH_2394|M.thermoresistible__bu      AQQARWGDGWVKLVGDWIDRSIGDLAPLWSDEVLKEAVDAAHAHGARVTA
MAB_3236c|M.abscessus_ATCC_199      ALQARWGDGWVKLVGDWIDRAVGDLAPLWSDKILKQAIDAAHANGARVTA
Mb2939c|M.bovis_AF2122/97           AEQARRGDGWVKLVGDWIDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTA
Rv2915c|M.tuberculosis_H37Rv        AEQARRGDGWVKLVGDWIDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTA
MMAR_1793|M.marinum_M               AAQARRGDGWIKLVGDWIDRQIGDLAPLWSDEVLKAAIDAAHANGARVTA
MUL_2041|M.ulcerans_Agy99           AAQARRGDGWIKLVGDWIDRQIGDLAPLWSDEVLKAAIDAAHANGARVTA
MAV_3769|M.avium_104                AQEAKRGDGWIKLVGDWIDRSVGDLAPLWSDEVLKAAIDTAHAHGARVTA
                                    . :*: ****:**:******  *********.:*. *: :***.******

Mflv_4181|M.gilvum_PYR-GCK          HVFGEDALPGLIKAGIDCIEHGTGLTEDSIGLMVEYGTALVPTLIN-IEN
Mvan_2182|M.vanbaalenii_PYR-1       HVFSEDALPGLIKAGIDCIEHGTGLTEDTIDLMVQHGTALVPTLIN-IEN
MSMEG_2431|M.smegmatis_MC2_155      HVFGEDALPGLIGAGIDCIEHGTGLTDDTIASMVEHGTALVPTLIN-VET
TH_2394|M.thermoresistible__bu      HVFGEDALPGLIKAGIDCIEHGTGLTDDTIELMVEHGTALVPTLIN-VEN
MAB_3236c|M.abscessus_ATCC_199      HVFGEDALPGLIHAGIDCIEHGTGLTDDTIALMVEHGTALVPTVIN-IEN
Mb2939c|M.bovis_AF2122/97           HVFSEDALPGLINAGIDCIEHGTGLTDDTIALMLEHGTALVPTLIN-LEN
Rv2915c|M.tuberculosis_H37Rv        HVFSEDALPGLINAGIDCIEHGTGLTDDTIALMLEHGTALVPTLIN-LEN
MMAR_1793|M.marinum_M               HVFGEDALPGLINAGIDCIEHGTGLTDDTISLMRDHGTALVPTLIN-VEN
MUL_2041|M.ulcerans_Agy99           HVFGEDALPGLINAGIDCIEHGTGLTDDTISLMRDHGTALVPTLIN-VEN
MAV_3769|M.avium_104                HVFSEDALPGLINAGIDCIEHGTGLTDDTIELMVSRGTALVPTLVNVVEN
                                    ***.******** *************:*:*  * . *******::* :*.

Mflv_4181|M.gilvum_PYR-GCK          FPGIAEAAGKYPTYARHMRDLYASCRDRVAAARDAGIPIFAGTDAGGMIA
Mvan_2182|M.vanbaalenii_PYR-1       FPDIAASADKYPAYQRHMRALYETCSARVGAAREAGVPIFAGSDAGSAVA
MSMEG_2431|M.smegmatis_MC2_155      FPGIADAAGKYPTYARHMRDLYASCYERVAAAHDAGVPIFAGTDAGGTIG
TH_2394|M.thermoresistible__bu      FPSIADRAVRYPTYAAHMRDLHERSYAQVSAAREAGVPVYAGTDAGGMIA
MAB_3236c|M.abscessus_ATCC_199      FPGIADKAGKYPKYAQHMRDLYAGLHTTFGNAYDAGIPIYAGTDAGGSIA
Mb2939c|M.bovis_AF2122/97           FPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAGVPVYAGTDAGSTIE
Rv2915c|M.tuberculosis_H37Rv        FPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAGVPVYAGTDAGSTIE
MMAR_1793|M.marinum_M               FPGIADSAVRYPTYAAHMRDLYASTYPRVAAAREAGIAIYAGTDAGGTIQ
MUL_2041|M.ulcerans_Agy99           FPGIADSAVRYPTYAAHMRDLYASTYPRVAAAREAGIAIYAGTDAGGTIQ
MAV_3769|M.avium_104                FPGIAQAAAKYPTYAAHMRDLYARGPSRIAAAREAGVPIYAGSDAGTMVA
                                    **.**  * :** *  *** *:      .. * :**:.::**:***  : 

Mflv_4181|M.gilvum_PYR-GCK          HGRIADEVEALKGIGMTPTEALGAACWDAREWLRRPTLRHGASADLVCFT
Mvan_2182|M.vanbaalenii_PYR-1       HGRIAEEVDALKGIGMTPTEALGAACWDARAWLRRPGLAHGASADLVCFA
MSMEG_2431|M.smegmatis_MC2_155      HGRISDEVEALKRIGMTPTHALGAACWDARAWLGRPGLEHGASADLLCFD
TH_2394|M.thermoresistible__bu      HGRIADEVEALKRIGMSSTEALGAASWNARSWLGRPGLEHGAPADLICYD
MAB_3236c|M.abscessus_ATCC_199      HGRISDEVAALTRIGMSPTDALGAASWRARSWLGRPGLEHGAPADLLGYR
Mb2939c|M.bovis_AF2122/97           HGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASADLLCYA
Rv2915c|M.tuberculosis_H37Rv        HGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASADLLCYA
MMAR_1793|M.marinum_M               HGRIADEVEALKKIGMSATEALGAACWEARRWLGRPTVEHGASADLVCFS
MUL_2041|M.ulcerans_Agy99           HGRIADEVEALKKIGMSATEALGAACWEARRWLGRPTVEHGASADLVCFS
MAV_3769|M.avium_104                PGRIADEVEALKGIGMTATQALGAACWDARRWLGRPGLEHGASADLLCFA
                                     ***::** **  ***:. .*****.* ** ** ** : . *.***: : 

Mflv_4181|M.gilvum_PYR-GCK          EDPLTGAEVLANPTRVILRGVVY--------
Mvan_2182|M.vanbaalenii_PYR-1       DDPRTGAGVLAHPTLVMLRGAAY--------
MSMEG_2431|M.smegmatis_MC2_155      EDPRVAG--ADHPDLVILRGRIF--------
TH_2394|M.thermoresistible__bu      EDPRLGPEVLTRPSRVILRGRVFQRPRR---
MAB_3236c|M.abscessus_ATCC_199      ADPRTGPGVLASPDLVMLRGQIR--------
Mb2939c|M.bovis_AF2122/97           QDPRQGPGVLQHPDLVILRGRTFGP------
Rv2915c|M.tuberculosis_H37Rv        QDPRQGPGVLQHPDLVILRGRTFGP------
MMAR_1793|M.marinum_M               EDPRRGAAILNRPDLVILRGRTYRPNQLGHR
MUL_2041|M.ulcerans_Agy99           EDPRRGAAILNRPDLVILRGRTYRPNQLGHR
MAV_3769|M.avium_104                EDPRSGPAVLRNPDLIMLRGNIFRSPA----
                                     **  .      *  ::***