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MNLMSAMAGAAQIGAVILGAPLVIGLMRQIRARSEGRCGAGILQPWRDLRKQLRKQQVTPEGTTAVFAVA PAVVAATTLLIAAIAPLVATGSPLDPVGDLFVVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALV EPTILLAVFALSIPAKSANLGAIVAFSLENPAEVVSLAGILAFVALVIVVIAETGRLPVDNPATHLELTM VHEAMVLEYAGPRLGVIEWASGMRLTVLLALLANLFVPWGIAGADPSLIGIAVGIAAISIKVAIAAGVLA TVEVFIAKLRLFRVPELLAGSFLLALLAVTSANFFTAQV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1656 | hycD | - | 100% (319) | formate hydrogenlyase HycD |
| M. marinum M | MMAR_1476 | nuoH | 2e-08 | 25.33% (225) | NADH dehydrogenase I (chain H) NuoH (NADH- ubiquinone |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0087 | hycD | 1e-141 | 81.15% (313) | formate hydrogenlyase HYCD |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0084 | hycD | 1e-141 | 81.15% (313) | formate hydrogenlyase HYCD |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2141 | - | 1e-07 | 24.15% (265) | NADH dehydrogenase subunit H |
| M. avium 104 | MAV_5112 | - | 1e-141 | 79.87% (318) | hydrogenase-4, C subunit, putative |
| M. smegmatis MC2 155 | MSMEG_3316 | - | 3e-05 | 24.75% (295) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1893 | hycD | 1e-168 | 99.37% (316) | formate hydrogenlyase HycD |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1656|M.marinum_M -------------------MNLMSAMAGAAQIGAVILGAPLVIG--LMRQ
MUL_1893|M.ulcerans_Agy99 ----------------------MSAMAGAAQIGAVILGAPLVIG--LMRQ
Mb0087|M.bovis_AF2122/97 ----------------------MSYLAGAAQIGGVMVGAPLVIG--MTRQ
Rv0084|M.tuberculosis_H37Rv ----------------------MSYLAGAAQIGGVMVGAPLVIG--MTRQ
MAV_5112|M.avium_104 -------------------MNVMSYVAGAAQILAVMAGAPLVIG--AMRQ
MAB_2141|M.abscessus_ATCC_1997 ------MTGRTDLSQFGIDPLWLVLVKCVAVFAFLVLTVLIAIL--AERR
MSMEG_3316|M.smegmatis_MC2_155 MTVTADSSAARENRWSTRLLIWAAVLILANVLVDIVIGSPLMVMPQLMAH
: . : :: : : :
MMAR_1656|M.marinum_M IRARSEGRCGA------GILQPWRDLRKQLRKQQVTPEGT-------TAV
MUL_1893|M.ulcerans_Agy99 IRARSEGRCGA------GILQPWRDLHKQLRKQQVTPEGT-------TAV
Mb0087|M.bovis_AF2122/97 VRARWEGRAGA------GLLQPWRDLLKQLGKQQITPAGT-------TIV
Rv0084|M.tuberculosis_H37Rv VRARWEGRAGA------GLLQPWRDLLKQLGKQQITPAGT-------TIV
MAV_5112|M.avium_104 VRARLEGRGGG------GVLQPWRDLRKQLGKQQISPQGT-------TVV
MAB_2141|M.abscessus_ATCC_1997 VLAWMQRRIGPNRVGPFGLLQSLADGVKLALKEGLTPAGVDKPIYLLAPI
MSMEG_3316|M.smegmatis_MC2_155 FDTDQAAWLNASAMLAGAIWAPLLAKSSDVFGKRRILVGTLVMAGVGALV
. : . .: . . : *. : :
MMAR_1656|M.marinum_M FAVAP---AVVAATTLLIAAIAPLVATGSPLDP---VGDLFVVVGLLFLG
MUL_1893|M.ulcerans_Agy99 FAVAP---AVVAATTLLIAAIAPLVATGSPLDP---VGDLFVVVGLLFLG
Mb0087|M.bovis_AF2122/97 FAAAP---VIVAGTTLLIAAIAPLVATGSPLDP---SADLFAVVGLLFLG
Rv0084|M.tuberculosis_H37Rv FAAAP---VIVAGTTLLIAAIAPLVATGSPLDP---SADLFAVVGLLFLG
MAV_5112|M.avium_104 FAAAP---AIVAGTTLLIVAIAPIVATGSPLDA---AADLFAVVGLLFLG
MAB_2141|M.abscessus_ATCC_1997 ISVVP---AIVAYAVIPFGPVVSVFGHRTPLQLTDLPVAILFVLAVTSVG
MSMEG_3316|M.smegmatis_MC2_155 CLAAPNLWIFLIGRFLQGAALAAVFLTVTLARQICAPGVAVVLVGLLTSG
..* .: : .:..:. : . ::.: *
MMAR_1656|M.marinum_M -TVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALS------I
MUL_1893|M.ulcerans_Agy99 -TVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALS------I
Mb0087|M.bovis_AF2122/97 -TVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALS------I
Rv0084|M.tuberculosis_H37Rv -TVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALS------I
MAV_5112|M.avium_104 -TVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALS------I
MAB_2141|M.abscessus_ATCC_1997 -VYGIVLGGWASGSTYPLLGGLRSSAQVISYEIAMGLTFAAVF------L
MSMEG_3316|M.smegmatis_MC2_155 PSIVGIIEPFLMKPVIDAFGYRSVFVVAALLATAAAIGVRCLVPESPIRI
: . :* . . : : . .: :
MMAR_1656|M.marinum_M PAKSANLGAIVAFS-LENPAEVVSLAGILAFVALVIVVIAETGR------
MUL_1893|M.ulcerans_Agy99 PAKSANLGAIVAFS-LENPAEVVSLAGILAFVALVIVVIAETGR------
Mb0087|M.bovis_AF2122/97 PAGSANLGALVAST-IDHPGHVVSLAGVLAFVALVIVIVAETGR------
Rv0084|M.tuberculosis_H37Rv PAGSANLGALVAST-IDHPGHVVSLAGVLAFVALVIVIVAETGR------
MAV_5112|M.avium_104 PAGSANLGALVTNT-IDHPGQVVSLTGLLAFVALVIVIVAETGR------
MAB_2141|M.abscessus_ATCC_1997 LAGTMSTSGIVAAQ-EGRWYLFLLLP---SFLVYVTAMVGETNR------
MSMEG_3316|M.smegmatis_MC2_155 AARIDVFGALLLGGGIGATLAYISLGQAVGWSDGRMIALLAAGAGALVWW
* ..:: : * .: : :.
MMAR_1656|M.marinum_M --LPVDNPATHLELTMVHEAMVLEYAGPRLGVIEWASGMRLT-VLLALLA
MUL_1893|M.ulcerans_Agy99 --LSVDNPATHLELTMVHEAMVLEYAGPRLGVIEWASGMRLT-VLLALLA
Mb0087|M.bovis_AF2122/97 --LPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLT-VLLALLA
Rv0084|M.tuberculosis_H37Rv --LPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLT-VLLALLA
MAV_5112|M.avium_104 --LPVDNPATHLELTMVHEAMVLEYAGPRLALVEWASGMRLT-VLLALLA
MAB_2141|M.abscessus_ATCC_1997 --APFDLPEAEGELVG---GFHTEYSSLRFAMFMLAEYINMA-TVSGLAA
MSMEG_3316|M.smegmatis_MC2_155 AVCALRVDEPLIDIRALHRPILLTLLALLLAAGSFRSMLQLTSVVAQVPV
.. . :: : . :. :.:: .: : .
MMAR_1656|M.marinum_M NLFVP----------------------------WG---------------
MUL_1893|M.ulcerans_Agy99 NLFVP----------------------------WG---------------
Mb0087|M.bovis_AF2122/97 NLFLP----------------------------WG---------------
Rv0084|M.tuberculosis_H37Rv NLFLP----------------------------WG---------------
MAV_5112|M.avium_104 NLFLP----------------------------WG---------------
MAB_2141|M.abscessus_ATCC_1997 TMFLGGWHAPWPLSLIDGANTSWLPALWFVAKVWGFMFLFMWLRATLPRL
MSMEG_3316|M.smegmatis_MC2_155 ELGLGYGLGHGEAIAILLAVPNLGIVVGGVCAGWVAGRGSGPARPLLGGI
: : *
MMAR_1656|M.marinum_M ------------------------------------------IAGADPSL
MUL_1893|M.ulcerans_Agy99 ------------------------------------------IAGADPSL
Mb0087|M.bovis_AF2122/97 ------------------------------------------IAGAAPTA
Rv0084|M.tuberculosis_H37Rv ------------------------------------------IAGAAPTA
MAV_5112|M.avium_104 ------------------------------------------IAGGHPSA
MAB_2141|M.abscessus_ATCC_1997 RYDQFMRLGWEV--------------------LIPVALVWIVVVGVVKAM
MSMEG_3316|M.smegmatis_MC2_155 TIGAVATFAMLLGVSALPLAIVCATMLGVAAGAISASGYNLAIDFAAPEH
:
MMAR_1656|M.marinum_M IGIAVGIAAISIKVAIAAGVLATVEVFIAKLRLFRVP--------ELLAG
MUL_1893|M.ulcerans_Agy99 IGIAVGIAAISIKVAIAAGVLATVEVFIAKLRLFRVP--------ELLAG
Mb0087|M.bovis_AF2122/97 LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVP--------ELLAG
Rv0084|M.tuberculosis_H37Rv LDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVP--------ELLAG
MAV_5112|M.avium_104 VDVAIGLAAITAKVTVLAVALAGAEVFIAKLRLFRVP--------ELLAG
MAB_2141|M.abscessus_ATCC_1997 GLYGYGNPSIILGITGVAVSLGSIGLVGVLSRRTQPPKPVLPARFDPMAG
MSMEG_3316|M.smegmatis_MC2_155 QGTIAGLVSVMLALGSVVFNFAGGEVLKATRILGMAAGG---APVSTAGG
* :: : . :. :. . . . .*
MMAR_1656|M.marinum_M SFLLALLAVTSANFFTAQV--------------------------
MUL_1893|M.ulcerans_Agy99 SFLLALLAVTSANFFTAQV--------------------------
Mb0087|M.bovis_AF2122/97 SFLLALLAVTAANFFTVGA--------------------------
Rv0084|M.tuberculosis_H37Rv SFLLALLAVTAANFFTVGA--------------------------
MAV_5112|M.avium_104 SFLLALLAVTAANFFTARA--------------------------
MAB_2141|M.abscessus_ATCC_1997 GFPVPPLPGQRVDTGAHPSTKEDADA-------------------
MSMEG_3316|M.smegmatis_MC2_155 VHLYVAMAGTLFALAAIPVIMLGRKRSPQAFRTGVDNAVEEACRR
. :. :