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MRSWWGWGNVEDALTEAETHALLSRVSALLPGHDLSDHQPPDPAALALPAARVSPPESLAGICSSDPIDR AGHARGKAFRDVTRNLLGHLDHVPDLIARPRSEQDVVDVLDWCTREQIPAIPYGGGSSVVGGVEPRFDQP AVTVDIGALGAVLEIDRVSRAARIQAGALGPSIEDQLRPHGLTLRHFPQSFGFSSLGGWLATRAGGHFAT LYTHIDDLTESMRVVSPAGVGESRRLPGSGAGPSPDRMFLGSEGTLGIITEAWMRLQDRPRWQLTASVEF DDWAGAVTATRAIAQAGLYPTNCRLLDPAEAFLNTGTAVSGGLLVLAFESADHPIDPWLDRAVEIAAGHG GTVTARRGRETRQAAAAQSGSDVSQAWRSAFLRMPYQRDALARRSVIAETFETACTWDGFDALHAAVTDA ARAAIERVCGVGLVTCRFTHVYPDGPAPYYGVYAAGRWGSLDAQWDEIKAAVSEAISTTGGTITHHHAVG RDHRPWYDRQRPDPFMAALRAAKTALDPAGILNPGVLLDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1525 | agpS | - | 100% (530) | alkyldihydroxyacetonephosphate synthase AgpS |
| M. marinum M | MMAR_3344 | - | 1e-77 | 34.62% (546) | flavoprotein |
| M. marinum M | MMAR_4183 | - | 6e-23 | 28.41% (447) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3134c | agpS | 0.0 | 81.51% (530) | alkyldihydroxyacetonephosphate synthase AgpS |
| M. gilvum PYR-GCK | Mflv_2772 | - | 7e-83 | 36.38% (547) | alkylglycerone-phosphate synthase |
| M. tuberculosis H37Rv | Rv3107c | agpS | 0.0 | 81.51% (530) | alkyldihydroxyacetonephosphate synthase AgpS |
| M. leprae Br4923 | MLBr_01103 | - | 5e-25 | 28.23% (457) | putative oxidoreductase subunit |
| M. abscessus ATCC 19977 | MAB_3884 | - | 8e-75 | 34.57% (538) | flavoprotein |
| M. avium 104 | MAV_2186 | - | 4e-85 | 36.56% (547) | flavoprotein |
| M. smegmatis MC2 155 | MSMEG_4334 | - | 9e-87 | 36.81% (546) | flavoprotein |
| M. thermoresistible (build 8) | TH_1507 | - | 3e-85 | 35.74% (540) | flavoprotein |
| M. ulcerans Agy99 | MUL_1298 | - | 3e-77 | 34.62% (546) | flavoprotein |
| M. vanbaalenii PYR-1 | Mvan_3761 | - | 3e-86 | 37.86% (552) | alkylglycerone-phosphate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3134c|M.bovis_AF2122/97 ----------MRSWWGWGTVEDALSDQETQALQSRVAALVSGHDLSDHPP
Rv3107c|M.tuberculosis_H37Rv ----------MRSWWGWGTVEDALSDQETQALQSRVAALVSGHDLSDHPP
MMAR_1525|M.marinum_M ----------MRSWWGWGNVEDALTEAETHALLSRVSALLPGHDLSDHQP
Mflv_2772|M.gilvum_PYR-GCK ----------MMQWNAWGDPDAAKPLSPGIRSLLHQALGIDGTPLDEPTL
Mvan_3761|M.vanbaalenii_PYR-1 ----------MMQWNAWGDPAAAKPLSPAIRALLGQALGIDGADIDEPTL
MSMEG_4334|M.smegmatis_MC2_155 -----------MKWNAWGDPQAAKPLSDGIRALLQQALGVTDSP-AQISP
TH_1507|M.thermoresistible__bu MSAPENHLSPPMKWNAWGDPAAARPLSDGIRSLLREALGVEGPPTPDLSP
MAV_2186|M.avium_104 -MTHPERLLPPMKWNAWGDPAAAKPLSEGIRSLLQQAVGIEGSRAAEPRP
MUL_1298|M.ulcerans_Agy99 -----------MKWNAWGDPAAAKPLSDGIRALLKQVVGLEDSDEAELGA
MAB_3884|M.abscessus_ATCC_1997 ----------MMEWDAWGVAEKRQTLSPQVKALLASALGIPEREPVHRDE
MLBr_01103|M.leprae_Br4923 -----------------------------MGVLTSLIAGLPDGMVVTDSA
:
Mb3134c|M.bovis_AF2122/97 PDLTALGLAAPRVSPPASLAALCSSDLVDRAG-----HARGKAYRDIARN
Rv3107c|M.tuberculosis_H37Rv PDLTALGLAAPRVSPPASLAALCSSDLVDRAG-----HARGKAYRDIARN
MMAR_1525|M.marinum_M PDPAALALPAARVSPPESLAGICSSDPIDRAG-----HARGKAFRDVTRN
Mflv_2772|M.gilvum_PYR-GCK -DQVRLRPSALSPGDRDGLSAIIGAEHVTVDDRARLLRAGGKSTLDLLRR
Mvan_3761|M.vanbaalenii_PYR-1 -EQVRLRPSALSPADLDGLSAVVGAANVTTDDQARLLRAGGKSTLDLLRR
MSMEG_4334|M.smegmatis_MC2_155 -EDITLRPSALTAADRDALAAVVGEQYCRTDDTARLLHAGGKSTLDLLRR
TH_1507|M.thermoresistible__bu -DQVRLRPSALSDADRDALAGVVGADFCRVDEHSRLLHAGGKSTLDLLRR
MAV_2186|M.avium_104 -EQVRLRPSTLSPADREALAAIVGPEYCRTADSDRLLHAGGKSTIDLLSR
MUL_1298|M.ulcerans_Agy99 -DQVKLRPCALSQSDQDALAKIVGPEYMRTADRDRLLRAGGKSTPDMLRR
MAB_3884|M.abscessus_ATCC_1997 -SHVTLTPNSLTDAQRAALGGLLGAEHVSTDHGARLRHSGGKSTPDLLRR
MLBr_01103|M.leprae_Br4923 VTDGYRHDRALDPSAG----------------------------------
: .
Mb3134c|M.bovis_AF2122/97 LQGQLDHLPDLIARPRSEQDVIDVLDWCAREGIAVIPYGGGSSVVGGVEP
Rv3107c|M.tuberculosis_H37Rv LQGQLDHLPDLIARPRSEQDVIDVLDWCAREGIAVIPYGGGSSVVGGVEP
MMAR_1525|M.marinum_M LLGHLDHVPDLIARPRSEQDVVDVLDWCTREQIPAIPYGGGSSVVGGVEP
Mflv_2772|M.gilvum_PYR-GCK RDFGVQDAPDAVLLPGGEDEIAEVLRYCAHRSIAVVPFGGGTSVVGGVDP
Mvan_3761|M.vanbaalenii_PYR-1 RDFGVQDAPDAIVLPGGDRDVAEVLRFCGERSIAVVPFGGGTSVVGGLDP
MSMEG_4334|M.smegmatis_MC2_155 NTSGVQDAPDAILLPGDEDAVAAILRYCTEHRIAIVPFGGGTSVVGGLDP
TH_1507|M.thermoresistible__bu RQP-EQDAPDAVVLPADEDQIAEILRICGSRRIAVVPFGGGTSVVGGLDP
MAV_2186|M.avium_104 NGPGPQDAPDAVLLPGDDESVAAILRYCSQHRIAVVPFGGGTSVVGGLTP
MUL_1298|M.ulcerans_Agy99 KDTGIQDAPDAVLLPGDDQAVAEILRYCSDQGIAIVPFGGGTNVTGALDP
MAB_3884|M.abscessus_ATCC_1997 RSTGVQNAPDAIVYPASHDEVSALLTLCEEQGIAVVPFGGGTSVVGGLDP
MLBr_01103|M.leprae_Br4923 -------KPLAVVQPRRTDEVQTVLRWASANRVPVVARGAGSGLSGGATA
* : * : :* . . :. :. *.*:.: *. .
Mb3134c|M.bovis_AF2122/97 RFD--EPVVTVDVTAMSAVLEIDRVSRAARIQAGAFGPSIEHQLRPHDLT
Rv3107c|M.tuberculosis_H37Rv RFD--EPVVTVDVTAMSAVLEIDRVSRAARIQAGAFGPSIEHQLRPHDLT
MMAR_1525|M.marinum_M RFD--QPAVTVDIGALGAVLEIDRVSRAARIQAGALGPSIEDQLRPHGLT
Mflv_2772|M.gilvum_PYR-GCK LRGDFKAVVSLDLRRLDELHSLDDVSWEAELGAGLTGPEAERLLGERGFS
Mvan_3761|M.vanbaalenii_PYR-1 TRGDFKAVVSLDLRRLDELHSLDEVSWEAELGAGLTGPDAERLLGERGFS
MSMEG_4334|M.smegmatis_MC2_155 LRGEFGAVVSLDLRRLDALHHLDEISGEAELGAGVTGPQAEELLGAHGFS
TH_1507|M.thermoresistible__bu IRGEFGSVVALDLRRLNRLIWLDEVSQLAELSAGMTGPAAEETLRARGFS
MAV_2186|M.avium_104 ERAGFGAAVAVDLRRFDQLISLDPVSGLAVLGAGVTGPDAEKLLGAHGFS
MUL_1298|M.ulcerans_Agy99 NRGQFSAVISLDLRRFNELHSLDEVSGIADLGAGVTGPDAERLLGERGFS
MAB_3884|M.abscessus_ATCC_1997 ERGAFGAVIAIDLRRMSGLLSLDEVSGTAVLLPGTTGPEAEELLGAQGFS
MLBr_01103|M.leprae_Br4923 LDDG----IVLSTEKMRDIT-VDPVTRTAVCQPGLFNAEVKKAAAEHGLW
: :. : : :* :: * .* .. : :.:
Mb3134c|M.bovis_AF2122/97 LRHFPQSFGFSTLGGWLATRSGGHFATLYTHIDDLTESLRIVTPVGISES
Rv3107c|M.tuberculosis_H37Rv LRHFPQSFGFSTLGGWLATRSGGHFATLYTHIDDLTESLRIVTPVGISES
MMAR_1525|M.marinum_M LRHFPQSFGFSSLGGWLATRAGGHFATLYTHIDDLTESMRVVSPAGVGES
Mflv_2772|M.gilvum_PYR-GCK LGHYPQSFLFATIGGFAATRSSGQDSAGYGRFNDMVRGLRAVTPAGVLDL
Mvan_3761|M.vanbaalenii_PYR-1 LGHFPQSFCFATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVLDL
MSMEG_4334|M.smegmatis_MC2_155 LGHFPQSFQFATIGGFAATRSSGQNSAGYGRFDDMVRGLRAVTPAGVLDL
TH_1507|M.thermoresistible__bu LGHFPQSFEFASIGGFAATRSSGQNSAGYGRFNDMVRGVRAITPTGVLDL
MAV_2186|M.avium_104 LGHFPQSFEYATIGGFAATRSSGQDSAGYGRFNDMVRGLRVITPVGTMDL
MUL_1298|M.ulcerans_Agy99 LGHFPQSFEYATIGGFAATRSSGQDSAGYGRFNDMIIGLRMITPAGVLDL
MAB_3884|M.abscessus_ATCC_1997 LGHFPQSFRFASIGGFAATRSSGQASSGYGRFDAMVDAVRIATPRGDLNL
MLBr_01103|M.leprae_Br4923 YPPDPSSFEICSIGGNVATNAGGLCCVKYGVTGDYVLGIQVVLADGTAVR
*.** .::** **.:.* . * . .:: . *
Mb3134c|M.bovis_AF2122/97 RRLP--GSGAGPSPDRLFLGSEGTLGIITEAWMRLQHRPRWQVTVSVVFD
Rv3107c|M.tuberculosis_H37Rv RRLP--GSGAGPSPDRLFLGSEGTLGIITEAWMRLQHRPRWQVTVSVVFD
MMAR_1525|M.marinum_M RRLP--GSGAGPSPDRMFLGSEGTLGIITEAWMRLQDRPRWQLTASVEFD
Mflv_2772|M.gilvum_PYR-GCK GRAP--ESAAGPDLRQLLIGSEGAFGIITRVRVRVHPVPEVTRYEAWSFP
Mvan_3761|M.vanbaalenii_PYR-1 GRAP--ASAAGPDLRQLLLGSEGTFGIITRVRVRVHPVPEATRYEAWSFP
MSMEG_4334|M.smegmatis_MC2_155 GRAP--ASAAGPDLRQLLLGSEGVFGVITRVRVRVHPVPESTRYEAWSFP
TH_1507|M.thermoresistible__bu GRAP--ESAAGPDLRHLLIGSEGVFGVITRVRVRVRPVPEAVRYEAWSFP
MAV_2186|M.avium_104 GRGP--ESAAGPDLRQLLIGSEGTLGVITRVRLRVHRIPQAVRYEAWSFP
MUL_1298|M.ulcerans_Agy99 GRVA--ASAAGPDLRQLAIGSEGVFGVITKVRLRVHPVPETTRYEAWSFP
MAB_3884|M.abscessus_ATCC_1997 GRAP--ASAAGPDLRQLFLGSEGALGIITEVTLRVHRLPEETWYQGWSFP
MLBr_01103|M.leprae_Br4923 LGGPRLKDVAGLSLTKLFVGSEGTLGIITEVTLRLLPTQNTSSIVVATFA
. . ** . :: :****.:*:**.. :*: . *
Mb3134c|M.bovis_AF2122/97 DWAAAVAATRTIAQAGLYPANCRLLDPAEALLNAGTS--------VGGGL
Rv3107c|M.tuberculosis_H37Rv DWAAAVAATRTIAQAGLYPANCRLLDPAEALLNAGTS--------VGGGL
MMAR_1525|M.marinum_M DWAGAVTATRAIAQAGLYPTNCRLLDPAEAFLNTGTA--------VSGGL
Mflv_2772|M.gilvum_PYR-GCK DFATGADALRAVVQTGTGPTVIRLSDEAETGVNLATTENIGEQKITGGCL
Mvan_3761|M.vanbaalenii_PYR-1 DFATGADALRAVAQTGTGPTVIRLSDEAETGVNLATTESIGEQQVTGGCL
MSMEG_4334|M.smegmatis_MC2_155 DFATGADALRAVVQTGTGPTVIRLSDEAETGVNLATTDNIGEQSITGGCL
TH_1507|M.thermoresistible__bu DFATGTAALRAVTQIGTGPTVIRLSDEAETGVNLATTDNIGDQSITGGCL
MAV_2186|M.avium_104 DFETGAAALRAVTQNGTGPTVIRLSDEAETGVNLATTEAIGESRITGGCL
MUL_1298|M.ulcerans_Agy99 DFSTGVAALRAITQTGTGPTVVRLSDEAETGINLATHESIGENQVTGGCL
MAB_3884|M.abscessus_ATCC_1997 SFEAGAQALRTLVQSDAAPTVLRLSDEAESGLNLALAKDIGGKNPAAGVL
MLBr_01103|M.leprae_Br4923 SVQAAVDAVLGVAAR-LRPAMLEFMDS--VAINAVEDTFRMGLDREAAAM
. .. * :. *: .: * :* .. :
Mb3134c|M.bovis_AF2122/97 LVLAFESADHPIDPWLHRAVAITAEHGGTVTAQRSRGTTSDATEHN---A
Rv3107c|M.tuberculosis_H37Rv LVLAFESADHPIDPWLHRAVAITAEHGGTVTAQRSRGTTSDATEHN---A
MMAR_1525|M.marinum_M LVLAFESADHPIDPWLDRAVEIAAGHGGTVTARRGRETRQAAAAQSGSDV
Mflv_2772|M.gilvum_PYR-GCK AITAFEGTEAHVASRHAETRDLLAAKGGTSLGEAP---------------
Mvan_3761|M.vanbaalenii_PYR-1 AITAFEGTEAHVASRHAETRDLLAASGGTSLGEGP---------------
MSMEG_4334|M.smegmatis_MC2_155 AVTVFEGSPEHTASRHAETRALLERLGGTSLGEVP---------------
TH_1507|M.thermoresistible__bu AITVFEGTAAHAESRHAETAAVLAAHGGTSLGEEP---------------
MAV_2186|M.avium_104 CITMFEGTEQHVDSRHAETRALLAAQGGTSLGDGP---------------
MUL_1298|M.ulcerans_Agy99 GLTLFEGTKEHTESRHAETRASLEAHGGKSLGEGP---------------
MAB_3884|M.abscessus_ATCC_1997 AITTVEGTHGHVAARSAEVAAVLSAAGGTALGDEP---------------
MLBr_01103|M.leprae_Br4923 LVAGSDELGHAGTDEAKLIGAVFAENGATQVSSTN---------------
: : *.. .
Mb3134c|M.bovis_AF2122/97 AANWRSAFLRMPYQRDALVRRGVIAETFETACTWDGFDTLHAAVTDA--A
Rv3107c|M.tuberculosis_H37Rv AANWRSAFLRMPYQRDALVRRGVIAETFETACTWDGFDTLHAAVTDA--A
MMAR_1525|M.marinum_M SQAWRSAFLRMPYQRDALARRSVIAETFETACTWDGFDALHAAVTDA--A
Mflv_2772|M.gilvum_PYR-GCK AKAWEHGRFNAPYLRDALLSAGALCETLETATNWSNVAALKAAVTEA--L
Mvan_3761|M.vanbaalenii_PYR-1 ARAWEHGRFNAPYLRDALLSAGALCETLETATNWSNVAALKAAVTEA--L
MSMEG_4334|M.smegmatis_MC2_155 ARAWEHGRFGAPYLRDSLLAAGALCETLETATNWSNVAALKTAVTEA--L
TH_1507|M.thermoresistible__bu ARAWEHGRFSAPYLRDSLLSAGALCETLETATTWSNIPTLKAAVTDA--L
MAV_2186|M.avium_104 ARAWERGRFGAPYLRDSLLAAGALCETLETATDWSNISALKAAVTQA--L
MUL_1298|M.ulcerans_Agy99 AQGWEHGRFSAPYLRDSLLAASALCETLETATDWSNIAAVKAAVTEA--L
MAB_3884|M.abscessus_ATCC_1997 AKAWDHGRFDAPYLRDALIDAGAVVETLETATSWQNLANLRTAVTTA--L
MLBr_01103|M.leprae_Br4923 ----------DPDEGEAFVAARRFCIPAVESKGSLLLEDVGVPLPALGKL
* ::: . . : . : ..:.
Mb3134c|M.bovis_AF2122/97 RTAIWKVCGTGVVTCRFTHVYPDGPAPYYGIYAGGRWGSLDAQWDEIKAA
Rv3107c|M.tuberculosis_H37Rv RTAIWKVCGTGVVTCRFTHVYPDGPAPYYGIYAGGRWGSLDAQWDEIKAA
MMAR_1525|M.marinum_M RAAIERVCGVGLVTCRFTHVYPDGPAPYYGVYAAGRWGSLDAQWDEIKAA
Mflv_2772|M.gilvum_PYR-GCK TRSLEDSGTPALVLCHISHVYPTGASLYFTVVAA-QRGNPIEQWRKAKAA
Mvan_3761|M.vanbaalenii_PYR-1 TGSLAESGTPALVLCHISHVYPTGASLYFTVVAA-QRGNPIEQWRNAKAA
MSMEG_4334|M.smegmatis_MC2_155 TATLAESGTQALVLCHISHVYPTGASLYFTVVAA-QRGDAAEQWRKAKTA
TH_1507|M.thermoresistible__bu TSTLGESGTSALVMCHISHVYPTGASLYFTVVAA-QRGNPIEQWRTAKAA
MAV_2186|M.avium_104 TTALAQTGTPALVMCHISHVYPTGASLYFTVVAG-QRGDPIEQWKTAKKA
MUL_1298|M.ulcerans_Agy99 TTSLAESGTPALVMCHVSHVYPTGASLYFTVVAG-QRGNPIEQWMAAKKA
MAB_3884|M.abscessus_ATCC_1997 AETLGAQGTPPLVLCHISHTYRTGASLYFTVVCA-AAEDALTQWGRAKQA
MLBr_01103|M.leprae_Br4923 VTGIAHISTERNLMISVIAHAGDGNTHPLIVYNP-ADATMTERAHRAFGE
: : . * : : :
Mb3134c|M.bovis_AF2122/97 VSEAISASGGTITHHHAVGRDHRAWYDRQRPDPFAAALRAAKSALDPAGI
Rv3107c|M.tuberculosis_H37Rv VSEAISASGGTITHHHAVGRDHRAWYDRQRPDPFAAALRAAKSALDPAGI
MMAR_1525|M.marinum_M VSEAISTTGGTITHHHAVGRDHRPWYDRQRPDPFMAALRAAKTALDPAGI
Mflv_2772|M.gilvum_PYR-GCK ASDAMVRTGATITHHHAVGADHRPWMTDEVGGLGVSVLRAVKSVLDPAGI
Mvan_3761|M.vanbaalenii_PYR-1 ASEAMLRSGATITHHHAVGADHRPWMRDEIGDLGVTVLRAVKEALDPAGI
MSMEG_4334|M.smegmatis_MC2_155 ASEAMVRNGATITHHHAVGADHRPWMTEEVGDLGVAVLRAVKATLDPAGI
TH_1507|M.thermoresistible__bu ASDAMMRHGGTITHHHAVGADHRPWMRDEVGGLGVDILRAVKATLDPAGI
MAV_2186|M.avium_104 ASDAIMATGGTITHHHAVGTDHRPWMPEEIGELGVQVLRAVKDTLDPAGI
MUL_1298|M.ulcerans_Agy99 ASDAMMATGATITHHHAVGADHRPWMRDEVGDLGVQLLRAVKATLDPAGI
MAB_3884|M.abscessus_ATCC_1997 AGDAIVAAGGTITHHHAVGRDHQPWLADEVGELGIEILQAVKRTVDPRGI
MLBr_01103|M.leprae_Br4923 IMDMAVGLGGTITGEHGVGRLKRPWLDDYLGPDVMELNQRIKHALDPYGI
: *.*** .*.** ::.* : * .:** **
Mb3134c|M.bovis_AF2122/97 LNPGVLLGR--
Rv3107c|M.tuberculosis_H37Rv LNPGVLLGR--
MMAR_1525|M.marinum_M LNPGVLLDR--
Mflv_2772|M.gilvum_PYR-GCK LNPGKLIP---
Mvan_3761|M.vanbaalenii_PYR-1 LNPGKLIP---
MSMEG_4334|M.smegmatis_MC2_155 LNPGKLIP---
TH_1507|M.thermoresistible__bu LNPGKLIP---
MAV_2186|M.avium_104 LNPGKLIP---
MUL_1298|M.ulcerans_Agy99 LNPGKLIP---
MAB_3884|M.abscessus_ATCC_1997 LNPGKLIPVQG
MLBr_01103|M.leprae_Br4923 LNPGAAI----
**** :