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MIPLSILDLSPISAGSTAATALRNTIELAQHAERWGYRRFWVAEHHFVAVASASPAVLIGQIAAATDRIR VGSAAVQLSHTTAAAVVESFGMLDAFHPGRIDLGVGRSAQRRGVKPRGPAKSLAPQPAREWREIDGVVIP PPFDLRTLLSGGRVQATMAILQQPEAVAPDFAEQVGDILALLAGTYRAEGFDVHAVPGENAALTPWIFGS SKGRSAQVAGALGLPFVASYHLTPATALEAIETYRDAFVPSAALQRPYVVVSADIVVAQDSATARRLASS YGHWVYSIRAGGGAAPYPDPDDCAALTDDQLAVVSDRLATQFVGNPDEVAERMLALQRVAGADELVVTSV THGHQDRLRSHELIARRWGLWS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0702 | - | - | 100% (372) | monooxygenase-like hypothetical protein |
| M. marinum M | MMAR_4179 | - | 1e-43 | 35.25% (366) | monooxygenase |
| M. marinum M | MMAR_2824 | - | 1e-08 | 28.22% (202) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0215 | - | 1e-153 | 71.54% (369) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 3e-06 | 31.25% (96) | monooxygenase |
| M. leprae Br4923 | MLBr_01106 | - | 3e-06 | 31.37% (102) | hypothetical protein MLBr_01106 |
| M. abscessus ATCC 19977 | MAB_4233c | - | 1e-118 | 58.38% (370) | putative monooxygenase (luciferase-like) |
| M. avium 104 | MAV_2049 | - | 1e-146 | 68.75% (368) | hypothetical protein MAV_2049 |
| M. smegmatis MC2 155 | MSMEG_5029 | - | 4e-42 | 33.80% (355) | alkanal monooxygenase alpha chain |
| M. thermoresistible (build 8) | TH_4411 | - | 3e-37 | 30.29% (373) | PUTATIVE putative alkanal monooxygenase alpha chain |
| M. ulcerans Agy99 | MUL_4481 | - | 7e-44 | 34.97% (366) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_4458 | - | 9e-38 | 32.58% (353) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0702|M.marinum_M --------------MIPLSILDLSPISAGSTAATALRNTIELAQHAERWG
Mflv_0215|M.gilvum_PYR-GCK -------------MNVPLSVLDLAPICDGSDAATALRNTVDLARHAERWG
MAV_2049|M.avium_104 ------------MTVTPLSILDLAPISAGCDAATALRNTIDLARHAERWG
MAB_4233c|M.abscessus_ATCC_199 -------------MNVPLSVLDLSPVSEGADATTALRNSIDLAQHAEQWG
TH_4411|M.thermoresistible__bu ---------------VPLSILDLVPISEGSTARDAIAASMNSARLADQLG
MSMEG_5029|M.smegmatis_MC2_155 ---------------MRLSVLDLVPVRTDQTTADALAATTHLAQTADRLG
Mvan_4458|M.vanbaalenii_PYR-1 --------------MMRLSVLDLVPVRSDQSTSDAIAASTLLAQTADRLG
MUL_4481|M.ulcerans_Agy99 ------------MGSVRLSVLDLVPVRTDQSTRDALAATVSLAQTAERLG
MLBr_01106|M.leprae_Br4923 MLAENILMAGGVDSIGRISVLDLVPVRTDQSSRHALVATVQLTQTANQRN
Rv3618|M.tuberculosis_H37Rv -----------MKAPLRFGVFITPFHPTGQSPTVALQYDMERVVALDRLG
:.:: . . *: . :: .
MMAR_0702|M.marinum_M YRRFWVAEHHFVA-VASASPAVLIGQIAAATDRIRVGSAAVQLSHTTAAA
Mflv_0215|M.gilvum_PYR-GCK YRRFWVAEHHFVA-VASTAPAVLIGQIAAATRTIRVGAAAVQLGQTTAVA
MAV_2049|M.avium_104 YHRYWLAEHHFVA-VASSAPVTLIGQIAAATSRIRVGTAAVQIGHTTAVA
MAB_4233c|M.abscessus_ATCC_199 YRRYWLAEHHFVA-VASTVPALVIAHIAAATHRIRVGAGAVQIASTTPAA
TH_4411|M.thermoresistible__bu YHRLWFAEHHNTPNLAASATALLISQAATVTERIRVGAGGVMLPNHAPLM
MSMEG_5029|M.smegmatis_MC2_155 YHRFWVAEHHNMPAVAATSPPVLIAHLAAHTSQLRLGSGGVMLPNHAPLA
Mvan_4458|M.vanbaalenii_PYR-1 YTRYWVAEHHNMPSVAATSPPVLIAHLAAHTASMRVGSGGVMLPNHAPLA
MUL_4481|M.ulcerans_Agy99 FTRYWVAEHHNMASVGATSPPVLIAYLAAQTTHLRLGSGGVMLPNHAPLA
MLBr_01106|M.leprae_Br4923 FSSRLVVEDYSMLSVGATSPPVLITYLAVQTTRIEL------LGNLGAVS
Rv3618|M.tuberculosis_H37Rv YDEAWFGEHHSGGYELIACPEVFIAAAAERTTHIRLGTGVVSLPYHHPLM
: . *.: : . .* * * :.: : .
MMAR_0702|M.marinum_M VVESFGMLDAFHPGRIDLGVGRSAQRRGVKPRGPAKSLAPQPAREWREID
Mflv_0215|M.gilvum_PYR-GCK VVETFGMLDAFHPGRIDLGIGRSG-RRARPPRPDGQKRTPRPVPPWREID
MAV_2049|M.avium_104 VVENFGILDALYPGRIDMGLGRSGQRRAEAAASSAAASPPE-ARPWRETD
MAB_4233c|M.abscessus_ATCC_199 VVESFGILDALYPGRIDLGLGRTGHRIRDRLAGNEQK--PEPAPAH-EVD
TH_4411|M.thermoresistible__bu VAEQYGTLANIHGDRIDLGLGRAPGTDMMTAR------------------
MSMEG_5029|M.smegmatis_MC2_155 VAEQFALLEAAHPGRIDLGIGRAPGSDPVTSLALRG--------------
Mvan_4458|M.vanbaalenii_PYR-1 VAEQFALLEAAHPGRIDLGIGRAPGSDPVTSLALRG--------------
MUL_4481|M.ulcerans_Agy99 VAEQFALLEAAAPGRIDLGIGRAPGSDPVTSYALRGG-------------
MLBr_01106|M.leprae_Br4923 ERASFNYTRSVSRARIDLG-------------------------------
Rv3618|M.tuberculosis_H37Rv VADRWVLLDHLTRGRVMFGTGPGALPSDAYMMGIDPVE------------
: *: :*
MMAR_0702|M.marinum_M GVVIPPPFDLRTLLSGGRVQATMAILQQPEAVAPDFAEQVGDILALLAGT
Mflv_0215|M.gilvum_PYR-GCK GVVIPSPFDLSTLMRNPRLKARMSVLQQPGAVSPEFADQVDDILALIAGR
MAV_2049|M.avium_104 GLVIPTPFDQTALMKSERIRAQSSVLAPPCAQPADFGEQIADIEAMLDGS
MAB_4233c|M.abscessus_ATCC_199 GLFIPRAPTEFGIKDNPKLRATAAALQQPGAHVADFDQQVADIQAFLDGS
TH_4411|M.thermoresistible__bu ------------------------ALSRSSAEPQDFARNIYDLQGWFSDT
MSMEG_5029|M.smegmatis_MC2_155 ------------------------AAGRDDRDIEAFPQYLDDVVALMGAR
Mvan_4458|M.vanbaalenii_PYR-1 ------------------------AAGRDERDIEAFPQYLDDVVALMSSK
MUL_4481|M.ulcerans_Agy99 -----------------------RSPAQQERDIESFPDYLDDVVALMSAR
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv --------------------QRRMMQESLEAILALFRAAPDERIDRHSDW
MMAR_0702|M.marinum_M YR---------AEGFDVHAVPGENAALTPWIFGSSKGRSAQVAGALGLPF
Mflv_0215|M.gilvum_PYR-GCK YE---------IDGFAAHVVPGEGSALTPWVFGSSKGESARVAGARGLPF
MAV_2049|M.avium_104 YA---------VNGHRLQVVPGEHAELTPWIFGSTRGQSAEVAGARGLPF
MAB_4233c|M.abscessus_ATCC_199 YVS--------PEGVALHIRPGEGADLPLWLFGSSKGESAQVAARRGLPF
TH_4411|M.thermoresistible__bu GT---------AHSMPIVSAVSAGTRVPIWVLGSTVN-GAAIAAQLGLPF
MSMEG_5029|M.smegmatis_MC2_155 GVRVPLPRDLLRDNYILKATPNATSVPQLWLLG-SSMYSAHLAAAKGLPY
Mvan_4458|M.vanbaalenii_PYR-1 GVRVPLPRDLMRDNYILKATPAAVTEPRLWLLG-SSMYSAQLAAAKGLPY
MUL_4481|M.ulcerans_Agy99 GARVPLQ----SGDYILKATSAALTQPRLWLLG-SSMYSARLAAAKGLPY
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv FT---------LREAQLHIRPYTWPYPEIATAAMISPSGPRLAGALGTSL
MMAR_0702|M.marinum_M VASYHLTPATALEAIETYRDAFV---PSAALQRPYVVVSADIVVAQDSAT
Mflv_0215|M.gilvum_PYR-GCK VASYHLTPATALDAVDVYRAHFR---PSATLTEPYVVVSADVVVAEDTAT
MAV_2049|M.avium_104 VASYHITPGTALDAIEAYRNAFR---PSARLARPYVVVSADVVVAEDSAT
MAB_4233c|M.abscessus_ATCC_199 VANYHVTPWSTVEAVEAYRDAFQ---PSKALAEPYVIVSADAVAADDETT
TH_4411|M.thermoresistible__bu AVASHFAPDQLDAALRTYREMFSTEAPTAQIDRPRVMAGINVMVADTDEE
MSMEG_5029|M.smegmatis_MC2_155 VFAHHFSGHGTAEALAIYREEFQ---PSEAAPEPVTFLTVNAVVAETTEE
Mvan_4458|M.vanbaalenii_PYR-1 VFAHHFAGQGTEEALQYYRDNFR---PSDLTPEPVTFLTVNAAVAETHDD
MUL_4481|M.ulcerans_Agy99 VFAHHFSGKGTEEALELYRSRFV---PSALAARPVTFLTVNAAVADTREE
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv LSLSMSVP-GGYAALETAWGVVREQAAKAGRGEPDRADWRVLSIMHLSDS
MMAR_0702|M.marinum_M ARRLASSYGHWVYSIRA--GGGAAPYPDPDDCAALTDDQLAVVSDRLATQ
Mflv_0215|M.gilvum_PYR-GCK ARHLASSYGHWVHAIRT--GDGAVPYPDPDRVAPLPDEQAATVKDRTATQ
MAV_2049|M.avium_104 ARHLASSYGHWVYSIRS--GQGAIPYPDPDLCDPLTEEQRALVADRTATQ
MAB_4233c|M.abscessus_ATCC_199 ARHLTSTFGRWVHSIRS--GHGAIPYPDPDVAQPLTEEERQHSEDRVATQ
TH_4411|M.thermoresistible__bu ARRQFTVVEQMFLDLKHNLRRKIQPPVDPDTLAAQGGGNEPMLR----IK
MSMEG_5029|M.smegmatis_MC2_155 AEALLLPQLQMMARLRTGQPLNALDLVEDAQTTVLTPQGDAVVADGRRRA
Mvan_4458|M.vanbaalenii_PYR-1 AMRLILPNLQMMARLRTGQPMVPIDLVEDAEAQVVSPRAQAVIDAGLRQA
MUL_4481|M.ulcerans_Agy99 ATALMMPNLHMMARLRTGQPLGPVQLVEEAQDARLTPEQQRIVDSGLERA
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv RDQAIDDCTYGLPDFSRYFGAAGFVPLANTVEGTQSSREFVEQYAAKGNC
MMAR_0702|M.marinum_M FVGNPDEVAERMLALQRVAG------------------------ADELVV
Mflv_0215|M.gilvum_PYR-GCK FVGDPDEVAHRLEALRRVAD------------------------ADELVI
MAV_2049|M.avium_104 FVGNPDEVADRLEVLRRVSG------------------------ADELVI
MAB_4233c|M.abscessus_ATCC_199 FVGDAGQVAERLDTLARVTG------------------------ADELVI
TH_4411|M.thermoresistible__bu AVGSPPTVKAQLDEFVARTG------------------------ADELIT
MSMEG_5029|M.smegmatis_MC2_155 VVGSPTEAAEQVRALAEEFD------------------------VDEVMI
Mvan_4458|M.vanbaalenii_PYR-1 VVGSPAEAGDQLRALAEKFG------------------------VDEVMV
MUL_4481|M.ulcerans_Agy99 VVGSPEEAAEQVRALGQRFG------------------------VDEVMV
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv CIGTPDDAIAHIEDLLHRSGGFGTLLLLGHDWAPPPATFHSYELFARAVI
MMAR_0702|M.marinum_M TSVTHGHQ--------DRLRSHELIARRWGLWS---------------
Mflv_0215|M.gilvum_PYR-GCK TSVTHGHE--------DRLRSHRLLAERWGITGEG-------------
MAV_2049|M.avium_104 TSVTHRHA--------DRLRSHELIAKRWGLTG---------------
MAB_4233c|M.abscessus_ATCC_199 TSITHRHE--------DRRRSYELIAKEWGLI----------------
TH_4411|M.thermoresistible__bu VTYAHDPA--------VRDRSLELLAKAWF------------------
MSMEG_5029|M.smegmatis_MC2_155 NPVASAHRGADPRTATARDTTLELLAKELF------------------
Mvan_4458|M.vanbaalenii_PYR-1 HPVASAFRGVDPATAPAREATLELLAKEIF------------------
MUL_4481|M.ulcerans_Agy99 HPVASAHRGTGPATAPARVATCELLAKELF------------------
MLBr_01106|M.leprae_Br4923 ------------------------------------------------
Rv3618|M.tuberculosis_H37Rv PYFKGQLAAPRASHEWARGKRDQLIGRAGEAVVKAITEHVAEQGEAGS