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TVTPLSILDLAPISAGCDAATALRNTIDLARHAERWGYHRYWLAEHHFVAVASSAPVTLIGQIAAATSRI RVGTAAVQIGHTTAVAVVENFGILDALYPGRIDMGLGRSGQRRAEAAASSAAASPPEARPWRETDGLVIP TPFDQTALMKSERIRAQSSVLAPPCAQPADFGEQIADIEAMLDGSYAVNGHRLQVVPGEHAELTPWIFGS TRGQSAEVAGARGLPFVASYHITPGTALDAIEAYRNAFRPSARLARPYVVVSADVVVAEDSATARHLASS YGHWVYSIRSGQGAIPYPDPDLCDPLTEEQRALVADRTATQFVGNPDEVADRLEVLRRVSGADELVITSV THRHADRLRSHELIAKRWGLTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2049 | - | - | 100% (373) | hypothetical protein MAV_2049 |
| M. avium 104 | MAV_1409 | - | 1e-38 | 31.73% (375) | alkanal monooxygenase alpha chain |
| M. avium 104 | MAV_2779 | - | 3e-08 | 27.87% (122) | limonene 1,2-monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0215 | - | 1e-147 | 68.02% (369) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 1e-05 | 30.11% (93) | monooxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4233c | - | 1e-129 | 61.41% (368) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_0702 | - | 1e-146 | 68.75% (368) | monooxygenase-like hypothetical protein |
| M. smegmatis MC2 155 | MSMEG_5029 | - | 1e-38 | 32.27% (375) | alkanal monooxygenase alpha chain |
| M. thermoresistible (build 8) | TH_4411 | - | 8e-35 | 30.19% (371) | PUTATIVE putative alkanal monooxygenase alpha chain |
| M. ulcerans Agy99 | MUL_4481 | - | 4e-39 | 31.28% (374) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_4458 | - | 5e-35 | 31.05% (351) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0215|M.gilvum_PYR-GCK --MNVPLSVLDLAPICDGSDAATALRNTVDLARHAERWGYRRFWVAEHHF
MMAR_0702|M.marinum_M ---MIPLSILDLSPISAGSTAATALRNTIELAQHAERWGYRRFWVAEHHF
MAV_2049|M.avium_104 -MTVTPLSILDLAPISAGCDAATALRNTIDLARHAERWGYHRYWLAEHHF
MAB_4233c|M.abscessus_ATCC_199 --MNVPLSVLDLSPVSEGADATTALRNSIDLAQHAEQWGYRRYWLAEHHF
TH_4411|M.thermoresistible__bu ----VPLSILDLVPISEGSTARDAIAASMNSARLADQLGYHRLWFAEHHN
MSMEG_5029|M.smegmatis_MC2_155 ----MRLSVLDLVPVRTDQTTADALAATTHLAQTADRLGYHRFWVAEHHN
Mvan_4458|M.vanbaalenii_PYR-1 ---MMRLSVLDLVPVRSDQSTSDAIAASTLLAQTADRLGYTRYWVAEHHN
MUL_4481|M.ulcerans_Agy99 -MGSVRLSVLDLVPVRTDQSTRDALAATVSLAQTAERLGFTRYWVAEHHN
Rv3618|M.tuberculosis_H37Rv MKAPLRFGVFITPFHPTGQSPTVALQYDMERVVALDRLGYDEAWFGEHHS
:.:: . . *: . :: *: . *..***
Mflv_0215|M.gilvum_PYR-GCK VA-VASTAPAVLIGQIAAATRTIRVGAAAVQLGQTTAVAVVETFGMLDAF
MMAR_0702|M.marinum_M VA-VASASPAVLIGQIAAATDRIRVGSAAVQLSHTTAAAVVESFGMLDAF
MAV_2049|M.avium_104 VA-VASSAPVTLIGQIAAATSRIRVGTAAVQIGHTTAVAVVENFGILDAL
MAB_4233c|M.abscessus_ATCC_199 VA-VASTVPALVIAHIAAATHRIRVGAGAVQIASTTPAAVVESFGILDAL
TH_4411|M.thermoresistible__bu TPNLAASATALLISQAATVTERIRVGAGGVMLPNHAPLMVAEQYGTLANI
MSMEG_5029|M.smegmatis_MC2_155 MPAVAATSPPVLIAHLAAHTSQLRLGSGGVMLPNHAPLAVAEQFALLEAA
Mvan_4458|M.vanbaalenii_PYR-1 MPSVAATSPPVLIAHLAAHTASMRVGSGGVMLPNHAPLAVAEQFALLEAA
MUL_4481|M.ulcerans_Agy99 MASVGATSPPVLIAYLAAQTTHLRLGSGGVMLPNHAPLAVAEQFALLEAA
Rv3618|M.tuberculosis_H37Rv GGYELIACPEVFIAAAAERTTHIRLGTGVVSLPYHHPLMVADRWVLLDHL
: . .*. * * :*:*:. * : . *.: : *
Mflv_0215|M.gilvum_PYR-GCK HPGRIDLGIGRSG-RRARPPRPDGQKRTPRPVPPWREIDGVVIPSPFDLS
MMAR_0702|M.marinum_M HPGRIDLGVGRSAQRRGVKPRGPAKSLAPQPAREWREIDGVVIPPPFDLR
MAV_2049|M.avium_104 YPGRIDMGLGRSGQRRAEAAASSAAASPPE-ARPWRETDGLVIPTPFDQT
MAB_4233c|M.abscessus_ATCC_199 YPGRIDLGLGRTGHRIRDRLAGNEQK--PEPAPAH-EVDGLFIPRAPTEF
TH_4411|M.thermoresistible__bu HGDRIDLGLGRAPGTDMMTAR-----------------------------
MSMEG_5029|M.smegmatis_MC2_155 HPGRIDLGIGRAPGSDPVTSLALRG-------------------------
Mvan_4458|M.vanbaalenii_PYR-1 HPGRIDLGIGRAPGSDPVTSLALRG-------------------------
MUL_4481|M.ulcerans_Agy99 APGRIDLGIGRAPGSDPVTSYALRGG------------------------
Rv3618|M.tuberculosis_H37Rv TRGRVMFGTGPGALPSDAYMMGIDPVE-----------------------
.*: :* *
Mflv_0215|M.gilvum_PYR-GCK TLMRNPRLKARMSVLQQPGAVSPEFADQVDDILALIAGRYE---------
MMAR_0702|M.marinum_M TLLSGGRVQATMAILQQPEAVAPDFAEQVGDILALLAGTYR---------
MAV_2049|M.avium_104 ALMKSERIRAQSSVLAPPCAQPADFGEQIADIEAMLDGSYA---------
MAB_4233c|M.abscessus_ATCC_199 GIKDNPKLRATAAALQQPGAHVADFDQQVADIQAFLDGSYVS--------
TH_4411|M.thermoresistible__bu -------------ALSRSSAEPQDFARNIYDLQGWFSDTGT---------
MSMEG_5029|M.smegmatis_MC2_155 -------------AAGRDDRDIEAFPQYLDDVVALMGARGVRVPLPRDLL
Mvan_4458|M.vanbaalenii_PYR-1 -------------AAGRDERDIEAFPQYLDDVVALMSSKGVRVPLPRDLM
MUL_4481|M.ulcerans_Agy99 ------------RSPAQQERDIESFPDYLDDVVALMSARGARVPLQ----
Rv3618|M.tuberculosis_H37Rv ---------QRRMMQESLEAILALFRAAPDERIDRHSDWFT---------
* :
Mflv_0215|M.gilvum_PYR-GCK IDGFAAHVVPGEGSALTPWVFGSSKGESARVAGARGLPFVASYHLTPATA
MMAR_0702|M.marinum_M AEGFDVHAVPGENAALTPWIFGSSKGRSAQVAGALGLPFVASYHLTPATA
MAV_2049|M.avium_104 VNGHRLQVVPGEHAELTPWIFGSTRGQSAEVAGARGLPFVASYHITPGTA
MAB_4233c|M.abscessus_ATCC_199 PEGVALHIRPGEGADLPLWLFGSSKGESAQVAARRGLPFVANYHVTPWST
TH_4411|M.thermoresistible__bu AHSMPIVSAVSAGTRVPIWVLGSTVN-GAAIAAQLGLPFAVASHFAPDQL
MSMEG_5029|M.smegmatis_MC2_155 RDNYILKATPNATSVPQLWLLG-SSMYSAHLAAAKGLPYVFAHHFSGHGT
Mvan_4458|M.vanbaalenii_PYR-1 RDNYILKATPAAVTEPRLWLLG-SSMYSAQLAAAKGLPYVFAHHFAGQGT
MUL_4481|M.ulcerans_Agy99 SGDYILKATSAALTQPRLWLLG-SSMYSARLAAAKGLPYVFAHHFSGKGT
Rv3618|M.tuberculosis_H37Rv LREAQLHIRPYTWPYPEIATAAMISPSGPRLAGALGTSLLSLSMSVP-GG
. . .. :*. * .
Mflv_0215|M.gilvum_PYR-GCK LDAVDVYRAHFR---PSATLTEPYVVVSADVVVAEDTATARHLASSYGHW
MMAR_0702|M.marinum_M LEAIETYRDAFV---PSAALQRPYVVVSADIVVAQDSATARRLASSYGHW
MAV_2049|M.avium_104 LDAIEAYRNAFR---PSARLARPYVVVSADVVVAEDSATARHLASSYGHW
MAB_4233c|M.abscessus_ATCC_199 VEAVEAYRDAFQ---PSKALAEPYVIVSADAVAADDETTARHLTSTFGRW
TH_4411|M.thermoresistible__bu DAALRTYREMFSTEAPTAQIDRPRVMAGINVMVADTDEEARRQFTVVEQM
MSMEG_5029|M.smegmatis_MC2_155 AEALAIYREEFQ---PSEAAPEPVTFLTVNAVVAETTEEAEALLLPQLQM
Mvan_4458|M.vanbaalenii_PYR-1 EEALQYYRDNFR---PSDLTPEPVTFLTVNAAVAETHDDAMRLILPNLQM
MUL_4481|M.ulcerans_Agy99 EEALELYRSRFV---PSALAARPVTFLTVNAAVADTREEATALMMPNLHM
Rv3618|M.tuberculosis_H37Rv YAALETAWGVVREQAAKAGRGEPDRADWRVLSIMHLSDSRDQAIDDCTYG
*: . .. .* .
Mflv_0215|M.gilvum_PYR-GCK VHAIRT--GDGAVPYPDPDRVAPLPDEQAATVKDRTATQFVGDPDEVAHR
MMAR_0702|M.marinum_M VYSIRA--GGGAAPYPDPDDCAALTDDQLAVVSDRLATQFVGNPDEVAER
MAV_2049|M.avium_104 VYSIRS--GQGAIPYPDPDLCDPLTEEQRALVADRTATQFVGNPDEVADR
MAB_4233c|M.abscessus_ATCC_199 VHSIRS--GHGAIPYPDPDVAQPLTEEERQHSEDRVATQFVGDAGQVAER
TH_4411|M.thermoresistible__bu FLDLKHNLRRKIQPPVDPDTLAAQGGGNEPMLR----IKAVGSPPTVKAQ
MSMEG_5029|M.smegmatis_MC2_155 MARLRTGQPLNALDLVEDAQTTVLTPQGDAVVADGRRRAVVGSPTEAAEQ
Mvan_4458|M.vanbaalenii_PYR-1 MARLRTGQPMVPIDLVEDAEAQVVSPRAQAVIDAGLRQAVVGSPAEAGDQ
MUL_4481|M.ulcerans_Agy99 MARLRTGQPLGPVQLVEEAQDARLTPEQQRIVDSGLERAVVGSPEEAAEQ
Rv3618|M.tuberculosis_H37Rv LPDFSRYFGAAGFVPLANTVEGTQSSREFVEQYAAKGNCCIGTPDDAIAH
. : :* . . :
Mflv_0215|M.gilvum_PYR-GCK LEALRRVAD------------------------ADELVITSVTHGHE---
MMAR_0702|M.marinum_M MLALQRVAG------------------------ADELVVTSVTHGHQ---
MAV_2049|M.avium_104 LEVLRRVSG------------------------ADELVITSVTHRHA---
MAB_4233c|M.abscessus_ATCC_199 LDTLARVTG------------------------ADELVITSITHRHE---
TH_4411|M.thermoresistible__bu LDEFVARTG------------------------ADELITVTYAHDPA---
MSMEG_5029|M.smegmatis_MC2_155 VRALAEEFD------------------------VDEVMINPVASAHRGAD
Mvan_4458|M.vanbaalenii_PYR-1 LRALAEKFG------------------------VDEVMVHPVASAFRGVD
MUL_4481|M.ulcerans_Agy99 VRALGQRFG------------------------VDEVMVHPVASAHRGTG
Rv3618|M.tuberculosis_H37Rv IEDLLHRSGGFGTLLLLGHDWAPPPATFHSYELFARAVIPYFKGQLAAPR
: : . . :
Mflv_0215|M.gilvum_PYR-GCK -----DRLRSHRLLAERWGITGEG-------------
MMAR_0702|M.marinum_M -----DRLRSHELIARRWGLWS---------------
MAV_2049|M.avium_104 -----DRLRSHELIAKRWGLTG---------------
MAB_4233c|M.abscessus_ATCC_199 -----DRRRSYELIAKEWGLI----------------
TH_4411|M.thermoresistible__bu -----VRDRSLELLAKAWF------------------
MSMEG_5029|M.smegmatis_MC2_155 PRTATARDTTLELLAKELF------------------
Mvan_4458|M.vanbaalenii_PYR-1 PATAPAREATLELLAKEIF------------------
MUL_4481|M.ulcerans_Agy99 PATAPARVATCELLAKELF------------------
Rv3618|M.tuberculosis_H37Rv ASHEWARGKRDQLIGRAGEAVVKAITEHVAEQGEAGS
* .*:..