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EGKDDGCISPQEGGTTRKPRRVGPDAKAKAGRTSATTDAAAQPGPDPTRDPVSDSPETCGGGHGGNTIGR APGTAEPSSQETELEVDHDDLDPGIQACAAAGDGPDPALEPGHDVTPQRRARSWTKVAAALAAAAVLAGT AALGWLWKEQRDTEIAGRQALSAALRFTENLTTIDSANIDENFRETIDGSTGEFKEMYLKSSAALQQALR ENKASAHGVVVESAIKSTSPDTVVVVLFVDQSVSNARAPEPRLDRSRVEVTMKKVDGRWLAAKVELP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0159 | - | - | 100% (278) | hypothetical protein MMAR_0159 |
| M. marinum M | MMAR_3870 | - | 2e-45 | 46.83% (205) | hypothetical protein MMAR_3870 |
| M. marinum M | MMAR_0161 | - | 2e-39 | 41.78% (213) | hypothetical protein MMAR_0161 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2411c | - | 7e-40 | 46.86% (175) | hypothetical protein Mb2411c |
| M. gilvum PYR-GCK | Mflv_0004 | - | 4e-45 | 43.55% (248) | hypothetical protein Mflv_0004 |
| M. tuberculosis H37Rv | Rv2390c | - | 4e-39 | 46.29% (175) | hypothetical protein Rv2390c |
| M. leprae Br4923 | MLBr_02615 | - | 6e-05 | 26.45% (155) | hypothetical protein MLBr_02615 |
| M. abscessus ATCC 19977 | MAB_4593c | - | 4e-46 | 41.11% (253) | hypothetical protein MAB_4593c |
| M. avium 104 | MAV_0098 | - | 7e-47 | 48.64% (220) | hypothetical protein MAV_0098 |
| M. smegmatis MC2 155 | MSMEG_1149 | - | 1e-42 | 46.31% (203) | hypothetical protein MSMEG_1149 |
| M. thermoresistible (build 8) | TH_0161 | - | 5e-42 | 51.18% (170) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4938 | - | 2e-54 | 99.07% (107) | hypothetical protein MUL_4938 |
| M. vanbaalenii PYR-1 | Mvan_0965 | - | 1e-47 | 53.85% (182) | hypothetical protein Mvan_0965 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2411c|M.bovis_AF2122/97 ---------------------------------MAIFG------------
Rv2390c|M.tuberculosis_H37Rv ---------------------------------MAIFG------------
MMAR_0159|M.marinum_M MEGKDDGCISPQEGGTTRKPRRVGPDAKAKAGRTSATTDAAAQPGPDPTR
MUL_4938|M.ulcerans_Agy99 --------------------------------------------------
MAB_4593c|M.abscessus_ATCC_199 -----------------MADDAADKDAKN-ADESAVTSDAEKAESSAPSS
Mflv_0004|M.gilvum_PYR-GCK ---------------------------------MTVTTQSTRDDEPDTSA
MSMEG_1149|M.smegmatis_MC2_155 ---------------------------------MKLKTDKRRD-VFDEAV
Mvan_0965|M.vanbaalenii_PYR-1 ---------------------------------MSVTTDRDLD---DEKT
TH_0161|M.thermoresistible__bu ---------------------------------VTLTDEDRDRTDRDETP
MAV_0098|M.avium_104 ---------------------------------MQLMNDRKPLQTVGNRG
MLBr_02615|M.leprae_Br4923 -----------------------------MRNRWRLLAFDVVAPLVAIAA
Mb2411c|M.bovis_AF2122/97 --------------------RGHGASEPGGTG------------------
Rv2390c|M.tuberculosis_H37Rv --------------------RGHGASEPGGTG------------------
MMAR_0159|M.marinum_M DPVSDSPETCGGGHGGNTIGRAPGTAEPSSQETELEVDHDDLDPGIQACA
MUL_4938|M.ulcerans_Agy99 --------------------------------------------------
MAB_4593c|M.abscessus_ATCC_199 AAVESTAE-------GTTEAATAEVADFDAEDSEKTKDSGAVED------
Mflv_0004|M.gilvum_PYR-GCK DDEQ------------TPEGAGPGDADVADAHTETE--------------
MSMEG_1149|M.smegmatis_MC2_155 DDTE------------DAEVEALDVAESEDTATEPESD-----EVTGPSG
Mvan_0965|M.vanbaalenii_PYR-1 DGEE------------DTTSQEEPDG-TEDSAAEDQ--------------
TH_0161|M.thermoresistible__bu EPES------------SEQVVTETSAEEAGETGETG--------------
MAV_0098|M.avium_104 TWLVRRFR-------VAAEGIADDEVAPADEPDVAEASPN----------
MLBr_02615|M.leprae_Br4923 LVMIG-----------VVLDWPRWWVSACSVLVLLIVEG-----------
Mb2411c|M.bovis_AF2122/97 ----------EPAETPGRGRLTRS---VTGWVGAVAVVVSLAGSGWCGWV
Rv2390c|M.tuberculosis_H37Rv ----------EPAETPGRGRLTRS---VIGWVGAVAVVVSLAGSGWCGWV
MMAR_0159|M.marinum_M AAGDGPDPALEPGHDVTPQR-RAR--SWTKVAAALAAAAVLAGTAALGWL
MUL_4938|M.ulcerans_Agy99 --------------------------------------------------
MAB_4593c|M.abscessus_ATCC_199 --SDDEDISLEPDEEENPKRIRGR--HWALTAAAIVAIAIVALAAIIGRL
Mflv_0004|M.gilvum_PYR-GCK --PADDDSD--PDEPMTARGWRRR--VLLGVVA-LVFAALLAVSGVLGWM
MSMEG_1149|M.smegmatis_MC2_155 EKPSDKPSDEKPAATVTSPNQRRG--VVLGVAAGILVAALLGGGGFVGWQ
Mvan_0965|M.vanbaalenii_PYR-1 -QPEDSASGD-PGPEAGNRSWRRR--VLAGAIAAVTIGAVAT-AGYLGWL
TH_0161|M.thermoresistible__bu -ETGETEKTGEPGEPGPAARSRRAGWLRVGAVT-AVFVVLLGLCGFLGWQ
MAV_0098|M.avium_104 -QSEQTDKAAEGEGEPPRPRKRRR-IKLVRAIAAGILAAVLATAGYEGWL
MLBr_02615|M.leprae_Br4923 -VGVNFWLLRRDSVTIGTDDDAPG----LRLAVVSVCTAALCAAVLIGYM
Mb2411c|M.bovis_AF2122/97 LFE--KHQTDVAAGQALQAARSYVVKLATMD----CERIDHNMRDILEGS
Rv2390c|M.tuberculosis_H37Rv LFE--KHQTDVAAGQALQAARSYVVKLATMD----CERIDHNMRDILEGS
MMAR_0159|M.marinum_M WKE--QRDTEIAGRQALSAALRFTENLTTID----SANIDENFRETIDGS
MUL_4938|M.ulcerans_Agy99 --------------------------MTTID----SANIDENFRETIDGS
MAB_4593c|M.abscessus_ATCC_199 YEE--QRIEEQSSREALAAAQEFANVMINVD----SAKLDESSNKTLERS
Mflv_0004|M.gilvum_PYR-GCK TWK--QHQLTQAGEQARQAAVTYAQVLTSID----SAKVDENFNQVLDGA
MSMEG_1149|M.smegmatis_MC2_155 LWQ--TKQVIAAGNQARDAAVNYAQVLTSID----SNKVDENFDQVLAGA
Mvan_0965|M.vanbaalenii_PYR-1 LWQ--QNQVSRAGEQAQAAAVQYAQILTSID----SAKVDENFDQVLDGA
TH_0161|M.thermoresistible__bu VWQ--QRQLDRAADEARQAAVEYARILTSID----ADKVDENFAQVLDGA
MAV_0098|M.avium_104 LFE--QHQKDVAAAQALDAAKKYILALTSVD----TNAIDKNFAEVLDGS
MLBr_02615|M.leprae_Br4923 HWTSPDRDFSLDSREVVQIATGMAEAMASFTPSAPTSSIDRAAAMIMPDQ
: .. :*. :
Mb2411c|M.bovis_AF2122/97 TGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTNKVVVLMFID
Rv2390c|M.tuberculosis_H37Rv TGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTNKVVVLMFID
MMAR_0159|M.marinum_M TGEFKEMYLKSSAALQQALRENKASAHGVVVESAIKSTSPDTVVVVLFVD
MUL_4938|M.ulcerans_Agy99 TGEFKEMYLKSSAALQQALRDNKASAHGVVVESAIKSTSPDTVVVVLFVD
MAB_4593c|M.abscessus_ATCC_199 TGDFKQKYSESSTTLRQVMIENKAKATGVVVDSAVKSAAPDKVEVLLFID
Mflv_0004|M.gilvum_PYR-GCK TGEFKDMYSESSMQLRQLLIDNKAASRGVVVESAIQSVEEGRVVVLLFVD
MSMEG_1149|M.smegmatis_MC2_155 TGEFKDMYSQSSMQLRQLLIENKATAHGVVVESAVQSATKNKAVVLLFVD
Mvan_0965|M.vanbaalenii_PYR-1 TGEFKDMYSQSSVQLRQLLIDNKASAHGVVVDSAIQSESKDKVVVLLFVD
TH_0161|M.thermoresistible__bu TGEFRDMYSASSAQLRQLLIDNKASARGVVLESAVQSAGEDEVVVLLFID
MAV_0098|M.avium_104 TGEFKDMYTKSSAQLRQTLIDNKAAAHGNVVDAAVRSATEDKVEVVLFVD
MLBr_02615|M.leprae_Br4923 AGVFKEQYRKSSADLARRNVTAQASVLAAGVEAIGSSAAS--VAVILRVT
:* *:: * ** * : :. . : : * . *:: :
Mb2411c|M.bovis_AF2122/97 QSVSNRNSPTPQIDRSRIKVIMDKVNGRWLASKVELL---
Rv2390c|M.tuberculosis_H37Rv QSVSNRNSPTPQIDRSRIKVIMDKVNGRWLASKVELL---
MMAR_0159|M.marinum_M QSVSNARAPEPRLDRSRVEVTMKKVDGRWLAAKVELP---
MUL_4938|M.ulcerans_Agy99 QSVSNARAPEPRLDRSRVEVTMKKVDGRWLAAKVELP---
MAB_4593c|M.abscessus_ATCC_199 QAVSNVAIPDARMDRSRVQITMQKVDGRWLASDVELT---
Mflv_0004|M.gilvum_PYR-GCK QSVTNSAVPDPRIDRSRIKMTMEYVDGRWRAAKVELA---
MSMEG_1149|M.smegmatis_MC2_155 QSVQNTAVPDPRIDRSRIKMTMEKVDGQWKASKVELP---
Mvan_0965|M.vanbaalenii_PYR-1 QSVSNTSVPDPRIDRSRVKMTMEYVDGRWRASKVELP---
TH_0161|M.thermoresistible__bu QTVSNAHVPEPRIDRSRVKMTMRHVDGTWRASKVALP---
MAV_0098|M.avium_104 QSVSNGAAPAPQLDRSRVKMTMEKVDGRWLASKVELP---
MLBr_02615|M.leprae_Br4923 QNTPGQP---PSQAAPAVRVTLIKRGSDWLVTDVLSINAR
* . . . . :.: : .. * .:.*