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NFLQEALSFIFTAANWGGPAGLSARILEHLQYTVIAVFFSAVIAVPLGMLIGHTGRGTFVVVTGVNALRA LPTLGVLLLGVLLWGLGLIPPTVALMLLGIPPLLAGTYSGIANVDRDVVDAARAMGMTESRILLRVETPI AMPLILGGLRTATLQIVATATVAAYASLGGLGRYLIDGIKVREFYLALVGALMVTALALILDAALAFAVW ASVPGSGRLHRSGSMPQPLLGDEVALESRSRAGRRPDSEARHERGNPSPTVEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5598 | - | - | 100% (264) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_5599 | - | 1e-15 | 25.23% (214) | binding-protein-dependent transport systems inner membrane |
| M. vanbaalenii PYR-1 | Mvan_0121 | - | 4e-14 | 25.69% (218) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 2e-88 | 70.17% (238) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_1210 | - | 1e-122 | 91.90% (247) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3756c | proZ | 2e-88 | 70.17% (238) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 1e-07 | 25.17% (151) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_0264 | - | 1e-95 | 71.49% (249) | osmoprotectant ABC transporter ProZ |
| M. marinum M | MMAR_5299 | proZ | 1e-89 | 74.32% (222) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. avium 104 | MAV_0320 | - | 6e-91 | 73.82% (233) | ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_6331 | - | 1e-117 | 80.52% (267) | ABC transporter, permease protein ProZ |
| M. thermoresistible (build 8) | TH_3904 | - | 5e-33 | 38.42% (177) | PUTATIVE conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_4374 | proZ | 2e-88 | 68.31% (243) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5598|M.vanbaalenii_PYR-1 ----------------------------------------------MNFL
Mflv_1210|M.gilvum_PYR-GCK ----------------------------------------------MNFL
MSMEG_6331|M.smegmatis_MC2_155 ----------------------------------------------MNFL
Mb3782c|M.bovis_AF2122/97 ----------------------------------------------MNFL
Rv3756c|M.tuberculosis_H37Rv ----------------------------------------------MNFL
MMAR_5299|M.marinum_M ----------------------------------------------MNFL
MUL_4374|M.ulcerans_Agy99 ----------------------------------------------MNFL
MAV_0320|M.avium_104 ----------------------------------------------MNFV
MAB_0264|M.abscessus_ATCC_1997 ----------------------------------------------MNFL
TH_3904|M.thermoresistible__bu ----VTATVDDTGDTGHTGCTGTAGDRASRSAARRWARRTVQPVLCLVAV
MLBr_02093|M.leprae_Br4923 MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSV
: :
Mvan_5598|M.vanbaalenii_PYR-1 QEALSFIFTAAN------WGGPA--GLSARILEHLQYTVIAVFFSAVIAV
Mflv_1210|M.gilvum_PYR-GCK QEALSFIFTAAN------WAGPA--GLTARILEHLQYTVIAVFFSALIAV
MSMEG_6331|M.smegmatis_MC2_155 QQALAFIFTAEN------WAGPS--GLGARIVEHLEYTAVAVFFSALIAV
Mb3782c|M.bovis_AF2122/97 QQALSYLLTASN------WTGPV--GLAVRTCEHLEYTAVAVAASALIAV
Rv3756c|M.tuberculosis_H37Rv QQALSYLLTASN------WTGPV--GLAVRTCEHLEYTAVAVAASALIAV
MMAR_5299|M.marinum_M QQALSYLSTAAN------WTGSA--GLAHRTAEHLEYTALAVTASALVAI
MUL_4374|M.ulcerans_Agy99 QQALSYLSTAAN------WTGSA--GLAHRTAEHLEYTALAATASALVAI
MAV_0320|M.avium_104 QRAIAYLLSADN------WTGPV--GLAARILEHLEYTGIAVGASALIAV
MAB_0264|M.abscessus_ATCC_1997 SNALGYIFTASH------WAGSS--GLGVRIGEHLEYTALAVLAAVVIAV
TH_3904|M.thermoresistible__bu GGALAYVHLADVSESEKRSLGVP--HLLMLLRQHMEISLAATVLTCAIAI
MLBr_02093|M.leprae_Br4923 VVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAV
* .: : * : . : : . : :*:
Mvan_5598|M.vanbaalenii_PYR-1 PLGMLIG------------HTGRGTFVVVTGVNALRALPTLGVLLLGVLL
Mflv_1210|M.gilvum_PYR-GCK PLGMLIG------------HTGRGTFVVVTGVNALRALPTLGVLLLGVLL
MSMEG_6331|M.smegmatis_MC2_155 PLGMVIG------------HTGRGTFLVVTGVNALRALPTLGVLLLGVLL
Mb3782c|M.bovis_AF2122/97 PVGLLIG------------HTGRGTLLVVGAVNGLRALPTLGVLLLGVLL
Rv3756c|M.tuberculosis_H37Rv PVGLLIG------------HTGRGTLLVVGAVNGLRALPTLGVLLLGVLL
MMAR_5299|M.marinum_M PIGLIIG------------HTGRGQLLVVSAVNGLRALPTLGVLLLGVLL
MUL_4374|M.ulcerans_Agy99 PIGLIIG------------HTGRGQLLVVSAVNGLRALPTLGVLLLGVLL
MAV_0320|M.avium_104 PVGLLIG------------HTGRGTLLVVGAVNGLRALPTLGVLLFGTLL
MAB_0264|M.abscessus_ATCC_1997 PLGLFIG------------HTGRGIFLVVSAVNALRALPTLGMLLLGVLL
TH_3904|M.thermoresistible__bu PLGVALTR----------GRFRRFATPIITVSGFGQAAPAIGLIALGAVL
MLBr_02093|M.leprae_Br4923 PLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLG
*:* : :: * : : :..:
Mvan_5598|M.vanbaalenii_PYR-1 WGLGLIPPTVALMLLGIPPLLAGTYSGIANVDRDVVDAARAMGMTESRIL
Mflv_1210|M.gilvum_PYR-GCK WGLGLIPPTVALMLLGIPPLLAGTYSGIANVDRSVVDAARSMGMTESRIL
MSMEG_6331|M.smegmatis_MC2_155 WGLGLVPPTVALMLLGIPPLLAGTYAGVANVERTVVDAARSMGMTESRIL
Mb3782c|M.bovis_AF2122/97 FGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVL
Rv3756c|M.tuberculosis_H37Rv FGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVL
MMAR_5299|M.marinum_M FGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEAQVV
MUL_4374|M.ulcerans_Agy99 FGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEAQVV
MAV_0320|M.avium_104 FGLGLGPSLVALMLLGVPALLAGTYAGIANVEPTVVDAARAMGMTESQVL
MAB_0264|M.abscessus_ATCC_1997 WGLGLVPPTVALLLLGVPPLLAGTYSGIANVDRTVVEAARAMGMTERQVL
TH_3904|M.thermoresistible__bu FGIGAVGAVAALTVYGALPIIANTVTGLNGVDDRLIEAARGMGMPTSTTL
MLBr_02093|M.leprae_Br4923 FQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWKTI
: . ** : :: .* : * : :*. .:*:. :
Mvan_5598|M.vanbaalenii_PYR-1 LRVETPIAMPLILGGLRTATLQIV-ATATVAAYASLGGLGRYLIDGIKVR
Mflv_1210|M.gilvum_PYR-GCK LRVETPNALPLILGGLRTATLQIV-ATATVAAYASLGGLGRYLIDGIKVR
MSMEG_6331|M.smegmatis_MC2_155 LRVEVPNALPLILGGLRTSTLQIV-ATATVAAYASLGGLGRYLIDGIKIR
Mb3782c|M.bovis_AF2122/97 LRVEVPNALPLMLGGLRSATLQVV-ATATVAAYASLGGLGGYLIDGIKER
Rv3756c|M.tuberculosis_H37Rv LRVEVPNALPLMLGGLRSATLQVV-ATATVAAYASLGGLGGYLIDGIKER
MMAR_5299|M.marinum_M LRVEMPNALPLILGGLRSATLQVV-ATATVAAYASLGGLGRYLIDGIKER
MUL_4374|M.ulcerans_Agy99 LRVEMPNALPLILGGLRSATLQVV-ATVTVAAYASLGGLGRYLIDGIKER
MAV_0320|M.avium_104 LRVEVPNALPLILGGLRSATLQVV-ATATVAAYASLGGLGRYLIDGIKER
MAB_0264|M.abscessus_ATCC_1997 FGVEVPNALPLILSGLRTATLQVV-ATATVAAYASLGGLGRYLIDGIKVR
TH_3904|M.thermoresistible__bu LRVELPLALPVIIAGVRTALVLIV-GTAALASFTGAGGLGQLITTGIKLQ
MLBr_02093|M.leprae_Br4923 VRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGNMA
. : * * * ::.*: : :: *..: .. . . :
Mvan_5598|M.vanbaalenii_PYR-1 EFYLALVGALMVTALALILDAALAFAVWASVPGSGRLHRSGS----MPQP
Mflv_1210|M.gilvum_PYR-GCK EFYLALVGALMVTALALILDALLAFAVWASVPGTGRLSRRRA----MPQP
MSMEG_6331|M.smegmatis_MC2_155 EFHIALVGAIMVTALALILDAALAFAVWLSVPGAGRLRGRRSGRGQMPQP
Mb3782c|M.bovis_AF2122/97 RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL----------
Rv3756c|M.tuberculosis_H37Rv RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL----------
MMAR_5299|M.marinum_M QFHIALVGALMVAALALSLDGLLALAGWASVPGTGRLSRFWH------QS
MUL_4374|M.ulcerans_Agy99 QSHIALVGALMVAALALSLDGLLALAGWASVPGTGRVSRFWH------QP
MAV_0320|M.avium_104 EFHLALVGALTVAALALVLDGLLAVAVWASVPGTGRLRRT----------
MAB_0264|M.abscessus_ATCC_1997 QFHLALVGAIMVTALALLLDAVLALAVWLSAPGTGRLRPVPD------LP
TH_3904|M.thermoresistible__bu QTVTLIVGAVLVAALALFIDWLARMVEVVAAPKGL---------------
MLBr_02093|M.leprae_Br4923 SLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFGAAFR-------
: : . * :
Mvan_5598|M.vanbaalenii_PYR-1 LLGDEVALESRSRAGRRPDSEARHERGNPSPTVEA
Mflv_1210|M.gilvum_PYR-GCK FLDDEVALESGSPAVRSPVTNGGSRRIR-------
MSMEG_6331|M.smegmatis_MC2_155 FLGDEVALESRTPNASARSSGVGYEGGAPSHTVEG
Mb3782c|M.bovis_AF2122/97 -----AAVVDKPAAGGGHALR--------------
Rv3756c|M.tuberculosis_H37Rv -----AAVVDKPAAGGGHALR--------------
MMAR_5299|M.marinum_M DDRIDVAVSPNSAAVGSHVLR--------------
MUL_4374|M.ulcerans_Agy99 DDRIDVAVSANSAAVGSHVLR--------------
MAV_0320|M.avium_104 -----YRPLPHRLAGTSYGR---------------
MAB_0264|M.abscessus_ATCC_1997 DREGHAVYADSGVSAGAMPRSPG------------
TH_3904|M.thermoresistible__bu -----------------------------------
MLBr_02093|M.leprae_Br4923 ------FLATRRCSGCR------------------