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M. thermoresistible (build 8) TH_3904 (-)

annotation: conserved hypothetical membrane protein
coordinates: 1502264 - 1503070
length: 269

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3904--100% (269)conserved hypothetical membrane protein
M. thermoresistible (build 8)TH_0698-7e-3237.62% (202) ABC transporter, permease protein OpuCB
M. thermoresistible (build 8)TH_4654-9e-1427.62% (181) PUTATIVE putative binding-protein-dependent transport systems

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3782cproZ1e-3036.51% (189) osmoprotectant (glycine betaine/carnitine/choline/L-proline)
M. gilvum PYR-GCKMflv_3110-1e-4840.29% (273) binding-protein-dependent transport systems inner membrane
M. tuberculosis H37RvRv3756cproZ1e-3036.51% (189) osmoprotectant (glycine betaine/carnitine/choline/L-proline)
M. leprae Br4923MLBr_02093pstA15e-0829.79% (141) membrane-bound component of phosphate transport
M. abscessus ATCC 19977MAB_1227-1e-10074.90% (255) ABC transporter permease
M. marinum MMMAR_0033-1e-10174.80% (250) hypothetical protein MMAR_0033
M. avium 104MAV_0320-2e-2934.10% (217) ABC transporter, permease protein
M. smegmatis MC2 155MSMEG_2925-1e-9869.40% (268) permease membrane component
M. ulcerans Agy99MUL_0032-1e-4882.76% (116) hypothetical protein MUL_0032
M. vanbaalenii PYR-1Mvan_5598-7e-3338.42% (177) binding-protein-dependent transport systems inner membrane

CLUSTAL 2.0.9 multiple sequence alignment


Mb3782c|M.bovis_AF2122/97           ------------------------------------------------MN
Rv3756c|M.tuberculosis_H37Rv        ------------------------------------------------MN
MAV_0320|M.avium_104                ------------------------------------------------MN
Mvan_5598|M.vanbaalenii_PYR-1       ------------------------------------------------MN
MAB_1227|M.abscessus_ATCC_1997      -----MTASTITATGAAQS---APATARRPALAAR-----QLLQPSACIV
MSMEG_2925|M.smegmatis_MC2_155      -----MTTTAPDTERVALP---AEPSSR--LGLGR-----WLIQPLVCVA
TH_3904|M.thermoresistible__bu      -----VTATVDDTGDTGHTGCTGTAGDRASRSAARRWA-RRTVQPVLCLV
MMAR_0033|M.marinum_M               -----MSVAGNDINVEGAVKGGAEGPPTAPTTPGRPSVGRWALQPLTCAF
MUL_0032|M.ulcerans_Agy99           -----MGAAATHVCLRGGR-------SAGLCDGGR---------CVRVGA
Mflv_3110|M.gilvum_PYR-GCK          -----MTATAEVSAEPSTDRESPGTGDPSGTTTAERLR--LLIQPVLVLV
MLBr_02093|M.leprae_Br4923          MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSV
                                                                                      

Mb3782c|M.bovis_AF2122/97           FLQQALSYLLTASNWT------GPVGLAVRTCEHLEYTAVAVAASALIAV
Rv3756c|M.tuberculosis_H37Rv        FLQQALSYLLTASNWT------GPVGLAVRTCEHLEYTAVAVAASALIAV
MAV_0320|M.avium_104                FVQRAIAYLLSADNWT------GPVGLAARILEHLEYTGIAVGASALIAV
Mvan_5598|M.vanbaalenii_PYR-1       FLQEALSFIFTAANWG------GPAGLSARILEHLQYTVIAVFFSAVIAV
MAB_1227|M.abscessus_ATCC_1997      AVMVSLAYVNLADVSASEKRSLGMSNLLVLLGQHMAISVAATVLTCAVAI
MSMEG_2925|M.smegmatis_MC2_155      AVAGSLLYVEVADVSESERRALGIGNLLTLLREHMVISVAATVLTCVLAI
TH_3904|M.thermoresistible__bu      AVGGALAYVHLADVSESEKRSLGVPHLLMLLRQHMEISLAATVLTCAIAI
MMAR_0033|M.marinum_M               AVAGALAYVTVADVSESERRSLSVSHLLQLLREHLVISLSATVLTCVVAI
MUL_0032|M.ulcerans_Agy99           PLAERVASVAAAALTPGDQP---VGHGAHVCGGD---SGGNRIDARTEAA
Mflv_3110|M.gilvum_PYR-GCK          VAGAVIFWAFNRQLTATQLENINPGNVATLIWQHLLITAAVTAIVLAIGI
MLBr_02093|M.leprae_Br4923          VVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAV
                                         .                               :          . 

Mb3782c|M.bovis_AF2122/97           PVG----LLIG--HTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLG
Rv3756c|M.tuberculosis_H37Rv        PVG----LLIG--HTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLG
MAV_0320|M.avium_104                PVG----LLIG--HTGRGTLLVVGAVNGLRALPTLGVLLFGTLLFGLGLG
Mvan_5598|M.vanbaalenii_PYR-1       PLG----MLIG--HTGRGTFVVVTGVNALRALPTLGVLLLGVLLWGLGLI
MAB_1227|M.abscessus_ATCC_1997      PLG----IALTRGPVRRYAKTITTLVGFGQAAPAIGLIALGAVLFGIGGI
MSMEG_2925|M.smegmatis_MC2_155      PLG----IALTRGSMRRYAKPIITVAGFGQAAPAIGLIALGAVLFGIGTT
TH_3904|M.thermoresistible__bu      PLG----VALTRGRFRRFATPIITVSGFGQAAPAIGLIALGAVLFGIGAV
MMAR_0033|M.marinum_M               PVG----IALTRGSMRRYSKPIITVAGFGQAAPAIGLIALGAVVFGIGQL
MUL_0032|M.ulcerans_Agy99           LFE----ADHHRRQFR---------SGRAGYRPDR---AGGGRVRDRSAR
Mflv_3110|M.gilvum_PYR-GCK          PLG----VLVTRPGAKVLRPLFVGIANVGQAAPAIGLLVLLFLLTAQTGF
MLBr_02093|M.leprae_Br4923          PLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLG
                                     .                        .     *          :      

Mb3782c|M.bovis_AF2122/97           PP------LVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVL
Rv3756c|M.tuberculosis_H37Rv        PP------LVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVL
MAV_0320|M.avium_104                PS------LVALMLLGVPALLAGTYAGIANVEPTVVDAARAMGMTESQVL
Mvan_5598|M.vanbaalenii_PYR-1       PP------TVALMLLGIPPLLAGTYSGIANVDRDVVDAARAMGMTESRIL
MAB_1227|M.abscessus_ATCC_1997      GA------VLALTVYGALPIVANTVIGLDGVDTRLVEAARGMGMSARSTL
MSMEG_2925|M.smegmatis_MC2_155      GS------IAALTVYGALPIIANTVIGLDGVDPRLVEAARGMGMSSFSAL
TH_3904|M.thermoresistible__bu      GA------VAALTVYGALPIIANTVTGLNGVDDRLIEAARGMGMPTSTTL
MMAR_0033|M.marinum_M               GA------IVALTVYGAMPIIANTVTGLDGVDRRIVEAARGMGLSAFSTL
MUL_0032|M.ulcerans_Agy99           RD------RCPHRLR-RDPIIANTVTGLDGVDRRIVEAARGMGLSAFSTL
Mflv_3110|M.gilvum_PYR-GCK          WIG-----VLPIALYSLLPVLSSTILGIDQVDRSLLDAGLGQGMSRRSLL
MLBr_02093|M.leprae_Br4923          FQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWKTI
                                              .  :     :: .*   :  *   : :*  . *:.    :

Mb3782c|M.bovis_AF2122/97           LRVEVPNALPLMLGGLRSATLQVVA-TATVAAYASLGGLGGYLIDGIKER
Rv3756c|M.tuberculosis_H37Rv        LRVEVPNALPLMLGGLRSATLQVVA-TATVAAYASLGGLGGYLIDGIKER
MAV_0320|M.avium_104                LRVEVPNALPLILGGLRSATLQVVA-TATVAAYASLGGLGRYLIDGIKER
Mvan_5598|M.vanbaalenii_PYR-1       LRVETPIAMPLILGGLRTATLQIVA-TATVAAYASLGGLGRYLIDGIKVR
MAB_1227|M.abscessus_ATCC_1997      IRVELPLALRVIVAGVRTALVLIVG-TAALASFTGAGGLGQLITTGIKLQ
MSMEG_2925|M.smegmatis_MC2_155      LKVELPLALRVIVAGVRTALVLIVG-TASLAAFTGGGGLGQLITVGIRLQ
TH_3904|M.thermoresistible__bu      LRVELPLALPVIIAGVRTALVLIVG-TAALASFTGAGGLGQLITTGIKLQ
MMAR_0033|M.marinum_M               RRVELPLSLPVIVAGVRTALVLIVG-TAALASFTGGGGLGQLITTGIKLQ
MUL_0032|M.ulcerans_Agy99           RRVELPLSLPVIVAGVRTALVLIVG-TAALASFTGGRGLGQLITTGIKLQ
Mflv_3110|M.gilvum_PYR-GCK          LRVELPLAVPYILAGLRTSLVLAVG-TATLSFLVNAGGLGILIDTGYKLQ
MLBr_02093|M.leprae_Br4923          VRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGNMA
                                     ::  * :   ::.*:  :    :. **.:   ..          . .  

Mb3782c|M.bovis_AF2122/97           RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAG
Rv3756c|M.tuberculosis_H37Rv        RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAG
MAV_0320|M.avium_104                EFHLALVGALTVAALALVLDGLLAVAVWASVPGTGRLRRTYRPLPHRLAG
Mvan_5598|M.vanbaalenii_PYR-1       EFYLALVGALMVTALALILDAALAFAVWASVPGSGRLHR-SGSMPQPLLG
MAB_1227|M.abscessus_ATCC_1997      QPVTLVVGAILVAALALFIDWLARVVEIIAAPRGL---------------
MSMEG_2925|M.smegmatis_MC2_155      QTTTLVVGAILVASLALFIDWLARVVEMLAAPKGLG--------------
TH_3904|M.thermoresistible__bu      QTVTLIVGAVLVAALALFIDWLARMVEVVAAPKGL---------------
MMAR_0033|M.marinum_M               QPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL---------------
MUL_0032|M.ulcerans_Agy99           QPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL---------------
Mflv_3110|M.gilvum_PYR-GCK          DNVTLILGSVLAVCLALLVDWLGGLAEFFLSPKGLR--------------
MLBr_02093|M.leprae_Br4923          SLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFGAAFRFLATRRC
                                         :   :     *  :                               

Mb3782c|M.bovis_AF2122/97           GGHALR--------------------------
Rv3756c|M.tuberculosis_H37Rv        GGHALR--------------------------
MAV_0320|M.avium_104                TSYGR---------------------------
Mvan_5598|M.vanbaalenii_PYR-1       DEVALESRSRAGRRPDSEARHERGNPSPTVEA
MAB_1227|M.abscessus_ATCC_1997      --------------------------------
MSMEG_2925|M.smegmatis_MC2_155      --------------------------------
TH_3904|M.thermoresistible__bu      --------------------------------
MMAR_0033|M.marinum_M               --------------------------------
MUL_0032|M.ulcerans_Agy99           --------------------------------
Mflv_3110|M.gilvum_PYR-GCK          --------------------------------
MLBr_02093|M.leprae_Br4923          SGCR----------------------------