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VGTRWVPESSGFTVTDLSVLRGISNVVSDSLFDLPGAPQPTDYGLGGSTGVPLAVRMRPASLDELVGQGH LLAPGSPLRRLVEGSGVVSAILHGPPGCGKTTLAALISQATGHRFEALSALSAGVKDVRAVLKIARSALL SGKRTVLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSLILQLRPLNADDIRAV VQRAVDDPRGLGGQIAVAPEAVDLLVRLAAGDARRVLTALEVAAEAVQTGDELTVATIEQSLDNAAVRYD RDGDQHYDIVSAFIKSVRGSDVDAALHYLARMLIAGEDPRFIARRLLILASEDIGLADSTALPLAVAAAQ TVQLIGMPEAQLALAHATIHLATAPKSNAVMTALGSAIDDIKAGKAGLVPAHLRDGHYSGAAALGNAKGY KYSHDDPDGVVAQQYPPYELVEVDYYRPTGRGGERELVGRLDRLRAIIRGRRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00510 | - | - | 100% (473) | recombination factor protein RarA |
| M. leprae Br4923 | MLBr_02335 | dnaZX | 2e-10 | 26.06% (307) | DNA polymerase III subunits gamma and tau |
| M. leprae Br4923 | MLBr_00483 | ruvB | 9e-10 | 25.35% (355) | Holliday junction DNA helicase RuvB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2589c | - | 0.0 | 84.38% (448) | recombination factor protein RarA |
| M. gilvum PYR-GCK | Mflv_3766 | - | 0.0 | 74.94% (447) | recombination factor protein RarA |
| M. tuberculosis H37Rv | Rv2559c | - | 0.0 | 84.15% (448) | recombination factor protein RarA |
| M. abscessus ATCC 19977 | MAB_2853c | - | 0.0 | 75.34% (446) | hypothetical protein MAB_2853c |
| M. marinum M | MMAR_2167 | - | 0.0 | 82.93% (451) | hypothetical protein MMAR_2167 |
| M. avium 104 | MAV_3435 | - | 0.0 | 85.23% (447) | recombination factor protein RarA |
| M. smegmatis MC2 155 | MSMEG_3021 | - | 0.0 | 77.56% (450) | recombination factor protein RarA |
| M. thermoresistible (build 8) | TH_0117 | - | 0.0 | 81.21% (447) | CONSERVED HYPOTHETICAL ALANINE LEUCINE VALINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_1751 | - | 0.0 | 82.48% (451) | recombination factor protein RarA |
| M. vanbaalenii PYR-1 | Mvan_2635 | - | 0.0 | 79.57% (421) | recombination factor protein RarA |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3766|M.gilvum_PYR-GCK --------------------------MSDSLFDVPGE-----PAPPAAGP
Mvan_2635|M.vanbaalenii_PYR-1 --------------------------------------------MPAGGP
MSMEG_3021|M.smegmatis_MC2_155 --------------------------MSDSLFDVPGGGAESGDAIAATGA
Mb2589c|M.bovis_AF2122/97 ----------------------MPEAVSDGLFDVPGVP----MTSGHDLG
Rv2559c|M.tuberculosis_H37Rv ----------------------MPEAVSDGLFDVPGVP----MTSGHDLG
MMAR_2167|M.marinum_M ----------------------MSEPVSDGLFDLPGAP----QHSDHGLE
MUL_1751|M.ulcerans_Agy99 ----------------------MSEPVSDGLFDLPGAP----QHSDHALE
MLBr_00510|M.leprae_Br4923 MGTRWVPESSGFTVTDLSVLRGISNVVSDSLFDLPGAP----QPTDYGLG
MAV_3435|M.avium_104 --------------------------MSDGLFDLPGAP----PPGDHGLG
TH_0117|M.thermoresistible__bu --------------------------VSDSLFDLPGEP----ASTAEPGA
MAB_2853c|M.abscessus_ATCC_199 --------------------------MSDSLFDVPGGG---FDSSSADPG
Mflv_3766|M.gilvum_PYR-GCK VGASVPLAVRMRPANLDEVVGQDHLLKPNSPLRRLIEGSGAASVILYGPP
Mvan_2635|M.vanbaalenii_PYR-1 AAASSPLAVRMRPASLDEVVGQGHLLKPNSPLRRLIEGSGAASVILYGPP
MSMEG_3021|M.smegmatis_MC2_155 VGPSSPLAVRMRPAGLDEVVGQSHLLQAGSPLRRLVEGSGAASVILYGPP
Mb2589c|M.bovis_AF2122/97 ASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPP
Rv2559c|M.tuberculosis_H37Rv ASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPP
MMAR_2167|M.marinum_M VSAGAPLAVRMRPESLDEVVGQGHLLAPGAPLRRLVEGSGVASVILYGPP
MUL_1751|M.ulcerans_Agy99 VSAGAPLAVRMRPESLDEVVGQGHLLAPGAPLRRLVEGSGVASVILYGPP
MLBr_00510|M.leprae_Br4923 GSTGVPLAVRMRPASLDELVGQGHLLAPGSPLRRLVEGSGVVSAILHGPP
MAV_3435|M.avium_104 VPAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASAILYGPP
TH_0117|M.thermoresistible__bu PTTPAPLAVRMRPANLDEVVGQDHLLQPGAPLRRLVEGSGAASVILYGPP
MAB_2853c|M.abscessus_ATCC_199 VPPNAPLAVRMRPATLDEVVGQGHLLKQGSPLRRLVDGSGAASVILYGPP
. ******** ***:***.*** .:*****::***..*.**:***
Mflv_3766|M.gilvum_PYR-GCK GTGKTTLASMISQATGRRFEALSALAAGVKEVRAVIDVARQAAV-RGEQT
Mvan_2635|M.vanbaalenii_PYR-1 GTGKTTLASMISQATGRRFEALSALAAGVKEVRAVIDVARQASM-RGEQT
MSMEG_3021|M.smegmatis_MC2_155 GTGKTTLASLISQATGRRFEALSALTAGVKEVRAVIDTARRAAV-HGQQT
Mb2589c|M.bovis_AF2122/97 GSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALL-HGEQT
Rv2559c|M.tuberculosis_H37Rv GSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALL-HGEQT
MMAR_2167|M.marinum_M GSGKTTLAALISHATGRRFEALSALSAGVKDVRAVIETARQVLR-RGEQT
MUL_1751|M.ulcerans_Agy99 GSGKTTLAALISHATGRRFEALSALSAGVKDVRAVIETARQVLR-RGEQT
MLBr_00510|M.leprae_Br4923 GCGKTTLAALISQATGHRFEALSALSAGVKDVRAVLKIARSALL-SGKRT
MAV_3435|M.avium_104 GSGKTTLAALISQATGRRFEALSALSAGVKDVRAVIESARTALL-RGEQT
TH_0117|M.thermoresistible__bu GTGKTTLASLISQATGRRFEALSALSAGVKEVRAVIDTARRAAM-RGEQT
MAB_2853c|M.abscessus_ATCC_199 GTGKTTLASLISGATGRRFEALSALSAGVKEVRAVIENSRTALAYHGQQT
* ******::** ***:********:****:****:. :* . *::*
Mflv_3766|M.gilvum_PYR-GCK VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
Mvan_2635|M.vanbaalenii_PYR-1 VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
MSMEG_3021|M.smegmatis_MC2_155 VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
Mb2589c|M.bovis_AF2122/97 VLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSL
Rv2559c|M.tuberculosis_H37Rv VLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSL
MMAR_2167|M.marinum_M VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
MUL_1751|M.ulcerans_Agy99 VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
MLBr_00510|M.leprae_Br4923 VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
MAV_3435|M.avium_104 VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
TH_0117|M.thermoresistible__bu VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
MAB_2853c|M.abscessus_ATCC_199 VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
*******************:***:**************************
Mflv_3766|M.gilvum_PYR-GCK ILQLQPLTPADVTTVIRRAITDERGLGGRVTVSDDAIEQLVLLSAGDARR
Mvan_2635|M.vanbaalenii_PYR-1 ILQLQPLTPEDVTTVIRRAIEDPRGLGGKVAVTDEAVDQLVQLSAGDARR
MSMEG_3021|M.smegmatis_MC2_155 ILQLQPLTPADIEAVLRRAITDERGLGGRVEVTDEAVDLIVQLSAGDARR
Mb2589c|M.bovis_AF2122/97 ILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARR
Rv2559c|M.tuberculosis_H37Rv ILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARR
MMAR_2167|M.marinum_M ILQLHPLGADDIRAVVQRAAQDPRGLGGRVAIAPDATDLLVQLSAGDARR
MUL_1751|M.ulcerans_Agy99 ILQLHPLGAEDIRAVVQRAAQDPRGLGGRVAIAPDATDLLVQLSAGDARR
MLBr_00510|M.leprae_Br4923 ILQLRPLNADDIRAVVQRAVDDPRGLGGQIAVAPEAVDLLVRLAAGDARR
MAV_3435|M.avium_104 ILQLRPLSADDIRTVVRRAIDDPRGLGGRVPVAPEAVDLLVRLAAGDARR
TH_0117|M.thermoresistible__bu ILQLQPLDTDAIRTVVRRAIDDPRGLGGKVEVSDDAVELLVQLSAGDARR
MAB_2853c|M.abscessus_ATCC_199 ILQLQPLADNDIREVLTRAIADERGLGGAVAVDPEALSLLVQLAAGDARR
****:** *: ** * **** : : :* . :* *:******
Mflv_3766|M.gilvum_PYR-GCK ALTALEVATETVSESGETVTVEVIEQSLDKAALRYDRDGDQHYDVVSAFI
Mvan_2635|M.vanbaalenii_PYR-1 ALTALEVASE----SGEEVTVEVIEQSLDKAAVRYDRDGDQHYDVVSAFI
MSMEG_3021|M.smegmatis_MC2_155 ALTALEVAAE----PGERVTVETIEQSLDKAAVRYDRDGDQHYDVVSAFI
Mb2589c|M.bovis_AF2122/97 ALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFI
Rv2559c|M.tuberculosis_H37Rv ALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFI
MMAR_2167|M.marinum_M ALTALEVAAEAAQAAGSQVSVEIIEQSLDKAAVRYDRDGDQHYDVVSAFI
MUL_1751|M.ulcerans_Agy99 ALTALEVAAEAAQAAGSQVSVEIIEQSLDKAAVRYDRDGDQHYDVVSAFI
MLBr_00510|M.leprae_Br4923 VLTALEVAAEAVQTG-DELTVATIEQSLDNAAVRYDRDGDQHYDIVSAFI
MAV_3435|M.avium_104 ALTALEVAAEAGES----VTVQTVEQSLDEAAVRYDRDGDQHYDVISAFI
TH_0117|M.thermoresistible__bu ALTALEVAAEAGER----VTVGTIEQSLDQAAVRYDRDGDQHYDVVSAFI
MAB_2853c|M.abscessus_ATCC_199 ALTALEVAFETAGGAGSVISVEVVEQSVDRAAVRYDRDGDQHYDVVSAFI
.******* * ::* :*:*:*.**:***********::****
Mflv_3766|M.gilvum_PYR-GCK KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGMADPTALQI
Mvan_2635|M.vanbaalenii_PYR-1 KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGMADPTALPT
MSMEG_3021|M.smegmatis_MC2_155 KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGMADPTALQT
Mb2589c|M.bovis_AF2122/97 KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADPSALQV
Rv2559c|M.tuberculosis_H37Rv KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMAGPSALQV
MMAR_2167|M.marinum_M KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGLADPTALPT
MUL_1751|M.ulcerans_Agy99 KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGLADPTALPT
MLBr_00510|M.leprae_Br4923 KSVRGSDVDAALHYLARMLIAGEDPRFIARRLLILASEDIGLADSTALPL
MAV_3435|M.avium_104 KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADSAALQV
TH_0117|M.thermoresistible__bu KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADPTALPL
MAB_2853c|M.abscessus_ATCC_199 KSIRGSDVDAALHYLARMLTAGEDPRFVARRLMILASEDVGMADPTALPL
**:**************** *******:****:******:*:*..:**
Mflv_3766|M.gilvum_PYR-GCK AVAAAQTVQLIGMPEAQLTLAQATVHLATAPKSNAVTTALGAAMADIRAG
Mvan_2635|M.vanbaalenii_PYR-1 AVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMADIRAG
MSMEG_3021|M.smegmatis_MC2_155 AVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMNDIRAG
Mb2589c|M.bovis_AF2122/97 AVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAG
Rv2559c|M.tuberculosis_H37Rv AVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAG
MMAR_2167|M.marinum_M AVAAAQTVALIGLPEAQLTLAHATIHLATAPKSNAVTTALAAAMADIKAG
MUL_1751|M.ulcerans_Agy99 AVAAAQTVALIGLPEAQLTLAHATIHLATAPKSNAVTTALAAAMADIKAG
MLBr_00510|M.leprae_Br4923 AVAAAQTVQLIGMPEAQLALAHATIHLATAPKSNAVMTALGSAIDDIKAG
MAV_3435|M.avium_104 AVAAAQTVALIGMPEAQLTLAHCTVYLATAPKSNAVTTALGAAMSDIKAG
TH_0117|M.thermoresistible__bu AVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMADIRAG
MAB_2853c|M.abscessus_ATCC_199 AVAAAQTVQLIGMPEAQLTLTHATIHLATAPKSGAVPAALGAAMGDIREG
******** ***:*****:*::.*::*******.** :**.:*: **: *
Mflv_3766|M.gilvum_PYR-GCK KAGQVPAHLRDGHYSGAQKLGNAVGYKYAHDHPGGVASQQYPPDELVGTD
Mvan_2635|M.vanbaalenii_PYR-1 KAGLVPAHLRDGHYSGAQKMGNAVGYKYAHDSPDGVVPQQYPPDDLVGVD
MSMEG_3021|M.smegmatis_MC2_155 KAGLVPPHLRDGHYSGAAKLGHAVGYRYSHDHPDGVVAQQYPPDELVGVD
Mb2589c|M.bovis_AF2122/97 KAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVD
Rv2559c|M.tuberculosis_H37Rv KAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVD
MMAR_2167|M.marinum_M KAGLVPPHLRDGHYSGAAALGHAQGYKYSHDDPDGVVAQQYPPDELVGTN
MUL_1751|M.ulcerans_Agy99 KAGLVPPHLRDGHYSGAAALGHAQGYKYSHDDPDGVVAQQYPPDELVGTN
MLBr_00510|M.leprae_Br4923 KAGLVPAHLRDGHYSGAAALGNAKGYKYSHDDPDGVVAQQYPPYELVEVD
MAV_3435|M.avium_104 KAGLVPAHLRDGHYSGAAALGHAQGYQYSHDHPDGVVAQQYPPDELVGVD
TH_0117|M.thermoresistible__bu KAGLVPAHLRDGHYSGAARLGHAQGYKYSHDHPDGVVAQQYPPDTLVGVD
MAB_2853c|M.abscessus_ATCC_199 KAGLVPPHLRDGHYSGAAKLGNAVGYVYPHNDRDGVVAQQYPPDELVGAD
*** **.********** :*:* ** *.*: .**..***** ** .:
Mflv_3766|M.gilvum_PYR-GCK YYRPTNHGVEREISARVEKLRAIIRRSR---
Mvan_2635|M.vanbaalenii_PYR-1 YYRPTNHGVEREISTRVDKLRAIIRRRR---
MSMEG_3021|M.smegmatis_MC2_155 YYQPTGRGYEREISTRLDKLRAIIRRRR---
Mb2589c|M.bovis_AF2122/97 YYRPTGRGGEREIAGRLDRLRAIIRKKRG--
Rv2559c|M.tuberculosis_H37Rv YYRPTGRGGEREIAGRLDRLRAIIRKKRG--
MMAR_2167|M.marinum_M YYRPTGRGGEREIGGRLERLRAIIRRKRA--
MUL_1751|M.ulcerans_Agy99 YYRPTGRGGEREIGGRLERLRAIIRRKRA--
MLBr_00510|M.leprae_Br4923 YYRPTGRGGERELVGRLDRLRAIIRGRRG--
MAV_3435|M.avium_104 YYRPTGRGAEREIAGRLDRLRAIIRNKRGRS
TH_0117|M.thermoresistible__bu YYRPTGRGAEREIAGRVDRLRAIIRGLRGRS
MAB_2853c|M.abscessus_ATCC_199 YYQPTDHGNEREIGSRLEKLRAIVRRGLKR-
**:**.:* ***: *:::****:*