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IGVVVIGLVGGMVAMTFASGSRVFGGAGSIFPLFMIGGVAMMMFSGRMGGQQQMSRPKLDAMRAQFMLML DMLREAANESADSMDANYRWFHPAPTTLAAAVGSSRMWERKPDGKDLNFCVVRVGVGMTRPEVTWGEPQN MPTDIELEPVTGKALQEFGRYQSIVYNLPKMVSLLVEPWYALIGDREQTLGLMRSIICQLTFSHGPDHVQ MVVVSSDLEQWDWVKWLPHFGDPRRQDAAGNARMVYSSVREFATEQAELFAGRGSFTPRHASSSAQTPTP HHLIVADVVDPEWEYVISVEGIDGVTFFDLTGSSMWTVVPKRTLRFDEKGVIDALPRDRDTWMVIDDKPW FFALADQLSFAEAEEFAQKLAHWRPAEAYEEIGQRVAHIGARDILSYYGIGDPSAIDFDALWNSRTDAMG KSRLRVPFGNRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLAHPPEELQFVLAD LKGGSAVKPFAGVPHVSRIITDLEEDQVLMERFLDALWGEIARRKAVCDNAGVDDAKEYNSVRTRMRARG QDMPALPMLVVVIDEFYEWFRIVPTAVDVLDSIGRQGRAYWIHLMMASQTIESRAEKLMENMGYRLVLKA RTAGAAQAAGVPNAVNLPAQAGLGYFRKSLEDVIRFQAEFLWRDYFRGVTLDGEEQPVLVHNIDYVRPQL FTNLFTPLEVSVGGPEVDAEAVFANAQEFDEEIAEEEAEGGVRTPKIGTVIIDQLRRIDFEPYRLWQPPL TQPVAIDDLVNRFLGHPWQKDYGSARNLVFPIGVIDRPFKHDQPAWTVDTSGPGSNVLVLGAGGSGKTTA LQTIICSAALTHTPEQVQFYCLGYSGTALTTVAHLPHVGEVAGPTDPYGVRRTVAELLALVRDRKRSFLE HGIASMEVFRRRKFGGELGPVPNDGFGDVYLVIDNYRALVEENEVLIEQVNQIINQGPSFGVHVVVTADR ESELRPQVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVQSGRGMVAVNYVRLDSDPQAGLHTLVARPAL ANTPANVFESDSVVAPVSRLTSAQAPPVRRLPARFGMEQVRERAVRDTRQGVGVGGIAWAISELDLQPVY LNFAENAHLMITGRRECGRTTVLATIMSEIGRLYAPGGTSAPPTSERSAQVWLIDPRRQLLTMLGSNYME KFAYNLDGVSAMVGELAALLASREPPPDLSAEELLSRSWWSGPEIFLIIDDIQQLPPSFDSPLQKVVPWV TRAGDVGLHVIATRTFGGWSSAGSDPMLRALHQANAPLLVMDADPDEGFIRGKMKGGPLPRGRGLLMAED TGVLVQVAETDMRR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_01543 | - | - | 100% (1345) | putative SpoIIIE-family membrane protein |
M. leprae Br4923 | MLBr_02535 | - | e-137 | 30.41% (1368) | hypothetical protein MLBr_02535 |
M. leprae Br4923 | MLBr_00052 | - | 2e-75 | 30.97% (607) | hypothetical protein MLBr_00052 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1812 | - | 0.0 | 87.27% (1351) | hypothetical protein Mb1812 |
M. gilvum PYR-GCK | Mflv_4959 | - | 1e-144 | 29.81% (1345) | cell divisionFtsK/SpoIIIE |
M. tuberculosis H37Rv | Rv1784 | - | 0.0 | 87.66% (932) | hypothetical protein Rv1784 |
M. abscessus ATCC 19977 | MAB_3756c | - | 0.0 | 33.41% (1359) | putative FtsK/SpoIIIE family protein |
M. marinum M | MMAR_2665 | - | 0.0 | 87.18% (1349) | FtsK/SpoIIIE family protein |
M. avium 104 | MAV_2932 | - | 0.0 | 86.81% (1349) | ftsk/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_1536 | - | 1e-148 | 30.63% (1358) | ftsk/SpoIIIE family protein |
M. thermoresistible (build 8) | TH_2597 | - | 1e-150 | 30.99% (1352) | PUTATIVE cell divisionFtsK/SpoIIIE |
M. ulcerans Agy99 | MUL_3092 | - | 0.0 | 86.89% (1350) | FtsK/SpoIIIE family protein |
M. vanbaalenii PYR-1 | Mvan_0413 | - | 1e-140 | 30.76% (1372) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4959|M.gilvum_PYR-GCK MVTVPCGTFSACGWNGAGVPCVYSYVDAGRIVLDAPPTPPAPTHTNVLAR TH_2597|M.thermoresistible__bu --------------------------------------VPRELPANPVAR MSMEG_1536|M.smegmatis_MC2_155 --------MEKTGRSDAG---------TGEVLIDAPPEVPRATPVPVVTR MAB_3756c|M.abscessus_ATCC_199 -------------------------MPGGEVNVQPPPEIPRPVPSPIIAK Mb1812|M.bovis_AF2122/97 ----------MKRGFARPTPEKPPVIKPENIVLSTPLSIPPPEGKPWWLI Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M ----------MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLI MUL_3092|M.ulcerans_Agy99 ----------MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLI MAV_2932|M.avium_104 ------------------------MIKPENIVLPTPLSIPPPEGKPWWLV MLBr_01543|M.leprae_Br4923 -------------------------------------------------- Mvan_0413|M.vanbaalenii_PYR-1 ---------MSRLIFEHRKRVPAPVVPKGTITIEPPPELPRVIPPSLLRR Mflv_4959|M.gilvum_PYR-GCK LMPVAMVAAMGGMTALYLTS-------TDATSRNPMFLFFPAMMAVSLIG TH_2597|M.thermoresistible__bu LLPLVMVVAMAGMLVLYFTS-------GNSAMRTPVFSFFPVLMVASAVG MSMEG_1536|M.smegmatis_MC2_155 VLPVVLVVAMVGMMVVYFRS-------GVATGRGPAVMFFPAMMAMSVLA MAB_3756c|M.abscessus_ATCC_199 IMPLVMVVAMVGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVS Mb1812|M.bovis_AF2122/97 VVGVVVVGLLGGMVAMVFASGS----HVFGGIGSIFPLFMMVGIMMMMFR Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M VVGVVVVGLLGGMVAMVFASGS----HVFGGVGSIFPIFMMVGIMMMMFR MUL_3092|M.ulcerans_Agy99 VVGVVVVGLLGGMVAMVFASGS----HVFGGVGSIFPIFMMVGIMMMMFR MAV_2932|M.avium_104 VVGVLVVGLLIGMVGMTFASGS----HVFGGAGAIFPIFMIGGVAMMMFG MLBr_01543|M.leprae_Br4923 MIGVVVIGLVGGMVAMTFASGS----RVFGGAGSIFPLFMIGGVAMMMFS Mvan_0413|M.vanbaalenii_PYR-1 ALPYLIVILIVGMIVALVATGLR--------MISPTMLFFP-FVLLLAAT Mflv_4959|M.gilvum_PYR-GCK TLAYGSRGAGRSGELAAQRAEYLRYLDTVDGALARAGEDLHRYLHAAHPA TH_2597|M.thermoresistible__bu TLAYGARGTHRTAELNADRRQYLRHLDELDRQAAAAATAQQRSLHRRHPR MSMEG_1536|M.smegmatis_MC2_155 TLAYSLRGNGGSAELERDRREYLRYLDGLDVLAAETARAQWQMLHDTFPE MAB_3756c|M.abscessus_ATCC_199 MVSNSGGKGAKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPD Mb1812|M.bovis_AF2122/97 GM-GGGQQQMSRPKLDAMRAQFMLMLDMLRETAQESADSMDANYRWFHPA Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M SVGAGGQQQMSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPA MUL_3092|M.ulcerans_Agy99 SVGAGGQQQMSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPA MAV_2932|M.avium_104 GR-FGGQQQMSRPKLDSMRAQFMLMLDMLRETAHESADSMDANYRWFHPA MLBr_01543|M.leprae_Br4923 GR-MGGQQQMSRPKLDAMRAQFMLMLDMLREAANESADSMDANYRWFHPA Mvan_0413|M.vanbaalenii_PYR-1 ALYRGTDNKMRTEEVDAERADYLRYLSVVRDNVRAYADQQRAALQWSHPE Mflv_4959|M.gilvum_PYR-GCK PAVLWTLAGTPRMWERAED--DPEFGMIRIGIGERAGATAVAAPGWVP-G TH_2597|M.thermoresistible__bu PDALWTLAGGPRMWERAPT--DPDFGRIRVGVAAQPLTPGLIPPDLPP-A MSMEG_1536|M.smegmatis_MC2_155 PAVLWMLADSDRRWERDTE--HRHFLEVRIGVGTRPLQTRLVAPESTG-G MAB_3756c|M.abscessus_ATCC_199 PSALWTLAGGRRMWERRPG--DSDYCHVRVGTGDQRLAAQLVAPEIGP-V Mb1812|M.bovis_AF2122/97 PNTLAAAVGSPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTD Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M PSTLAAAVGSPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTD MUL_3092|M.ulcerans_Agy99 PSTLAAAVGSPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTD MAV_2932|M.avium_104 PTTLAAAVGSPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTD MLBr_01543|M.leprae_Br4923 PTTLAAAVGSSRMWERKPDGKDLNFCVVRVGVGMTRPEVTWGEPQNMPTD Mvan_0413|M.vanbaalenii_PYR-1 PAALVSIPGTRRQWERDPH--DPDFLVLRAGLHDQPLATALRVKDTAD-E Mflv_4959|M.gilvum_PYR-GCK DDADPVTTEAVQRLLAHRETVGDVPVTLSLRSVRTLAICGEPAAARSVAR TH_2597|M.thermoresistible__bu EEADPVTVSAVQRLLRVRATVPDLPDTVAVFDHSAITVTGDDAHG--LAR MSMEG_1536|M.smegmatis_MC2_155 AEQDPVTVEALEALLRARSTVDDVPVTVRLGGHYRLTGPDDQVAG--LVR MAB_3756c|M.abscessus_ATCC_199 EELEPVASVALRRFVRTHSLVPELPIALNLRGFAAVTIDGSPEVARGMLR Mb1812|M.bovis_AF2122/97 IELEPVTGKALQEFGRYQSVVYNLPKMVSLLVEPWYALVGEREQVLGLMR Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M IELEPVTGKALQEFGRYQSVVYNLPKMISLLVEPWYALVGEREQALGLMR MUL_3092|M.ulcerans_Agy99 IELEPVTGKALQEFGRYQSVVYNLPKMISLLVEPWYALVGEREQALGLMR MAV_2932|M.avium_104 IELEPVTGKALQEFGRYQSVVYNLPKMISLLVEPWYSLAGDREQVLGLMR MLBr_01543|M.leprae_Br4923 IELEPVTGKALQEFGRYQSIVYNLPKMVSLLVEPWYALIGDREQTLGLMR Mvan_0413|M.vanbaalenii_PYR-1 IDLEPVSHSTLRSLLDTQRTIHDAPAGVDLTKVARITVIGDRAEVAGALR Mflv_4959|M.gilvum_PYR-GCK ALLCQIATLHHPDTMSISAAPVTD----WDWLKWLPHQRS---------- TH_2597|M.thermoresistible__bu AMICQLAVLHGPDVLRIATVTTGDDGV-WDWLKWLPHHRHPWCTGHL--- MSMEG_1536|M.smegmatis_MC2_155 AVLCQLATWHSPRDVKIAAAPHADDR--WDWLKWLPHHTN---------- MAB_3756c|M.abscessus_ATCC_199 AMICQLAMFHGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTS Mb1812|M.bovis_AF2122/97 AIICQLAFSHGPDHVQMIVVSSDLDQ--WDWVKWLPHFGDSRRHDAAGNA Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M AIICQLTFSHGPDHVQFIVVSSDLAE--WEWVKWLPHFGDSRRYDAAGNA MUL_3092|M.ulcerans_Agy99 AIICQLTFSHGPDHVQFIVVSSDLAE--WEWVKWLPHFGDSRRYDAAGNA MAV_2932|M.avium_104 AIICQLTFSHGPDHVRMIVVSSDLDE--WDWVKWLPHFGDPRRQDAAGNA MLBr_01543|M.leprae_Br4923 SIICQLTFSHGPDHVQMVVVSSDLEQ--WDWVKWLPHFGDPRRQDAAGNA Mvan_0413|M.vanbaalenii_PYR-1 AWIAQAVTWHDPSVLGVAFAGTRLESDAWSWLKWLPHTDVPGQNDGVGPA Mflv_4959|M.gilvum_PYR-GCK -----------------------------SQEGRH--HVVVADEG----- TH_2597|M.thermoresistible__bu --------------------RHRDLTEIDRAADRA--RWLVIRDG----- MSMEG_1536|M.smegmatis_MC2_155 -----------------------------TPYDGA--AHLVIVAD----- MAB_3756c|M.abscessus_ATCC_199 RLVYHSLGEVEESLASLITERERFSRTAQPSPDRP--QILIVVDSGTLIG Mb1812|M.bovis_AF2122/97 RMVYTSVREFAAEQAELFAGRGSFTPRHASSSAQTPTPHTVIIADVDDPQ Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M RMVYSSVREFAAEQGELFAGRGSFTPRHASSSAQTPTPHTVIICDVDDPQ MUL_3092|M.ulcerans_Agy99 RMVYSSVREFAAEQGELFAGRGSFTPRHASSSAQTPTPHTVIICDVDDPQ MAV_2932|M.avium_104 RMVYSSVREFAAEQAELFAGRGSFTPRHASSSAQTPTPHTVIIADAVDPQ MLBr_01543|M.leprae_Br4923 RMVYSSVREFATEQAELFAGRGSFTPRHASSSAQTPTPHHLIVADVVDPE Mvan_0413|M.vanbaalenii_PYR-1 RYLATEPAALHALLAPALAERAP-----FTGDGPTDAKHLLVVLDDPDAD Mflv_4959|M.gilvum_PYR-GCK --VSARDGTT--LIILTAGSGAPTVTADG----------VPVAA------ TH_2597|M.thermoresistible__bu --HRGEDAAPPGVTVLTVASAADSIRTDE----------LLLDTGDR--- MSMEG_1536|M.smegmatis_MC2_155 --SPVSDTLPDGATVLGLGSDATDASATR----------IDVEHDEVRI- MAB_3756c|M.abscessus_ATCC_199 SERLIVDHGIDSVTLVEIGTRVDPLAARRG---------MQLELTERGLG Mb1812|M.bovis_AF2122/97 WEYVISAEGVDGVTFFDLTGSSMWTDIPERKLQFDKTGVIEALPRDRDTW Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M WEYVISAEGVDGVTFFDLTGSPMWTNVPERKLEFDKTGVIEALPRDRDTW MUL_3092|M.ulcerans_Agy99 WEYVISAEGVDGVTFFDLTGSPMWTNVPERKLEFDKTGVIEALPRDRDTW MAV_2932|M.avium_104 WEYVISAEGVDGVTFFDLTGSSMWSSVPERTLRFDDKGVIEALPRDRDTW MLBr_01543|M.leprae_Br4923 WEYVISVEGIDGVTFFDLTGSSMWTVVPKRTLRFDEKGVIDALPRDRDTW Mvan_0413|M.vanbaalenii_PYR-1 PGQFIGRGLAGVTVIHRTDREPDRDQYPDPERP------VLRVAARRIER Mflv_4959|M.gilvum_PYR-GCK -----------VCDQMSEAEAAACARRIARHRPRR--------PSRSLRR TH_2597|M.thermoresistible__bu ---------DRCTDSLSPVAALACARRLSAFRTAA--------VRNRSPW MSMEG_1536|M.smegmatis_MC2_155 ------ATVSARPDTMTAEQALACARRLARYRAEA--------ASAR-RS MAB_3756c|M.abscessus_ATCC_199 AKGNVGSEVFAHPDHLTITEAMACARRLAPYRVLTGSGDE-VQIQTEVST Mb1812|M.bovis_AF2122/97 MVIDDKAWFFALTDQVSIAEAEEFAQKLAQWRLAEAYEEIGQRVAHIGAR Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M MVIDDNAWFFALTDHVSIAEAEEFGQKLAQWRLAEAYEEIGQRVAHIGAR MUL_3092|M.ulcerans_Agy99 VVIDDNAWFFALTDHVSIAEAEEFGQKLAQWRLAEAYEEIGQRVAHIGAR MAV_2932|M.avium_104 MVIDEKPWFFALTDHLSVAEAEEFAQKLARWRLAEAYEEIGQRVAHIGAR MLBr_01543|M.leprae_Br4923 MVIDDKPWFFALADQLSFAEAEEFAQKLAHWRPAEAYEEIGQRVAHIGAR Mvan_0413|M.vanbaalenii_PYR-1 WLNGSWVPFVDAADRMAPDDARHIARRLARWDSNPHHG----RSASAGGA Mflv_4959|M.gilvum_PYR-GCK DWPALMGIDDPDALDVDVRWSRD---LGSDLLRVPIG-VADDGSVVELDI TH_2597|M.thermoresistible__bu NWLELMDVDDPELLP-DTRWADTGG-AGAVLSPVPLG-VSETGARLDLDI MSMEG_1536|M.smegmatis_MC2_155 DWANLLGVDDITHLGIERVWQNLD---PRQRLRVPIG-ISDHGVRVDLDL MAB_3756c|M.abscessus_ATCC_199 RWSDIVGIGDPGLLNPEVVWRNR---VGRDRLRVPIG-IAVDGTPMELDI Mb1812|M.bovis_AF2122/97 DILSYYGIDDPGNIDFDSLWASRTDTMGRSRLRAPFGNRSDNGELLFLDM Rv1784|M.tuberculosis_H37Rv --------------------------MGRSRLRAPFGNRSDNGELLFLDM MMAR_2665|M.marinum_M DILAYYGIDDPGNIDFDYLWGSRTDSMGRSRLRAPFGNRSDNGELLFLDM MUL_3092|M.ulcerans_Agy99 DILAYYGIDDPGNIDFDYLWGSRTDSMGRSRLRAPFGNRSDNGELLFLDM MAV_2932|M.avium_104 DILSYYGIEDPGNIDFDALWGGRTDTMGRSRLRAPFGVRSDNGELLFLDM MLBr_01543|M.leprae_Br4923 DILSYYGIGDPSAIDFDALWNSRTDAMGKSRLRVPFGNRSDNGELLFLDM Mvan_0413|M.vanbaalenii_PYR-1 AFTTLLGIPDASALDVAALWAPRN---RDDELRVPIG-VTATGEPLIFDL .*:* : * : :*: Mflv_4959|M.gilvum_PYR-GCK KEAAAHGMGPHGLCVGATGSGKSEFLRTLVLGMVCAHPPGLLNLVLVDFK TH_2597|M.thermoresistible__bu NEAARGGMGPHGLCVGATGSGKSELLRTLVLGLITVHPPEVLNLILVDFK MSMEG_1536|M.smegmatis_MC2_155 NEAARGGSGPHGLCIGATGSGKSEFLRTLVLGLITTHSPDALNLVLVDFK MAB_3756c|M.abscessus_ATCC_199 KEAAENGMGPHGLCIGATGSGKSEFLRTLTLGMIATHSPDALNLVLVDFK Mb1812|M.bovis_AF2122/97 KSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLSHPPEELQFVLADLK Rv1784|M.tuberculosis_H37Rv KSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLSHPPEELQFVLADLK MMAR_2665|M.marinum_M KSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLGHPPEELQFVLADLK MUL_3092|M.ulcerans_Agy99 KSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLGHPPEELQFVLADLK MAV_2932|M.avium_104 KSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLSHPPEELQFVLADLK MLBr_01543|M.leprae_Br4923 KSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLAHPPEELQFVLADLK Mvan_0413|M.vanbaalenii_PYR-1 KDEAEGGMGPHGLMIGMTGSGKSQTLMAILLSLLTTHPADRLIVIYADFK :. * ****: * ****** : :: .:: *.. * .: .*:* Mflv_4959|M.gilvum_PYR-GCK GGATFLGLEAVHHVSAVITNLADEAPLVSRMRDALSGEITRRQEMLRAAG TH_2597|M.thermoresistible__bu GGATFLGLERANHVSAVITNLSDEAHLVARMYDALSGELNRRQELLRAAG MSMEG_1536|M.smegmatis_MC2_155 GGATFLGLASAPHISALITNLSDEAAMVARMADALAGEMTRRQELLRAA- MAB_3756c|M.abscessus_ATCC_199 GGATFLGLDRAQHVAAIITNLAEEANLVSRMKDALAGEMNRRQELLRAAG Mb1812|M.bovis_AF2122/97 GGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG Rv1784|M.tuberculosis_H37Rv GGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG MMAR_2665|M.marinum_M GGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG MUL_3092|M.ulcerans_Agy99 GGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG MAV_2932|M.avium_104 GGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG MLBr_01543|M.leprae_Br4923 GGSAVKPFAGVPHVSRIITDLEEDQVLMERFLDALWGEIARRKAVCDNAG Mvan_0413|M.vanbaalenii_PYR-1 GEAGADIFRNFPQVVAVISNMAEKRSLADRFADTLRGEVARREQLLLEAG * : : :: :*::: :. : *: *:* **: **: : * Mflv_4959|M.gilvum_PYR-GCK ---NLTNITQYAQ---ARARDDTLAPLPALLVIVDEFSELLTQHPDFSEV TH_2597|M.thermoresistible__bu ---NAADLAEYTA---ARATRPDLPLLPALLIAVDEFSELLAQHPEFAEL MSMEG_1536|M.smegmatis_MC2_155 ---NVGSAAEYTR---TNGR----PPLPTLLVVVDEFSELLHQHPDFADL MAB_3756c|M.abscessus_ATCC_199 ---NFANVTEYER---ARAAGASLSPLPALFIIVDEFSELLSQHPDFAEL Mb1812|M.bovis_AF2122/97 ---VDDAKEYNSVRARMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDV Rv1784|M.tuberculosis_H37Rv ---VDDAKEYNSVRARMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDV MMAR_2665|M.marinum_M ---VDDAKEYNSVRGRMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDV MUL_3092|M.ulcerans_Agy99 ---VDDAKEYNSVRGRMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDV MAV_2932|M.avium_104 ---VDDAKEYNAVRARMRARGQDMPPLPMLVVVIDEFYEWFRIMPTAVDV MLBr_01543|M.leprae_Br4923 ---VDDAKEYNSVRTRMRARGQDMPALPMLVVVIDEFYEWFRIVPTAVDV Mvan_0413|M.vanbaalenii_PYR-1 RRIQNSAFNSVTEYENAIAEGHDLPPLPTLFVVADEFTLMLAEHPEYADL . . ** *.: *** : * :: Mflv_4959|M.gilvum_PYR-GCK FVAIGRLGRSLGIHLLLATQRLDEGRLRGLETHLSYRVCLKTFSAGESRA TH_2597|M.thermoresistible__bu FVAIGRLGRSLGMHLLLSSQRVDEGRLRGLETHLSYRICLKTFSAGDSRA MSMEG_1536|M.smegmatis_MC2_155 FVAIGRLGRSLGIHLLLASQRLDEGRLRGLESHLSYRICLKTFSAAESRA MAB_3756c|M.abscessus_ATCC_199 FVAIGRLGRSLHVHLLLASQRLDEGRLRGLESHLSYRLCLKTFSANESRA Mb1812|M.bovis_AF2122/97 LDSIGRQGRAYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQ Rv1784|M.tuberculosis_H37Rv LDSIGRQGRAYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQ MMAR_2665|M.marinum_M LDSIGRQGRAYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQ MUL_3092|M.ulcerans_Agy99 LDSIGRQGRAYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQ MAV_2932|M.avium_104 LDSIGRQGRAYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQ MLBr_01543|M.leprae_Br4923 LDSIGRQGRAYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQ Mvan_0413|M.vanbaalenii_PYR-1 FDYVARKGRSFRIHLLFASQTLDVGRIKDIDKNTSYRIGLKVASPAVSRQ : :.* **: :**::::* :: * . : : .**: **. :. : Mflv_4959|M.gilvum_PYR-GCK VLGVPDAYSLSS---QPGAAYLKTAS-GVLTRFQTAYVSGGYTPASRPRS TH_2597|M.thermoresistible__bu VLGVPDAYQLPA---RPGAALLKTVS-DELVRFQTAYVSGPLLRTREKPA MSMEG_1536|M.smegmatis_MC2_155 VLGVADAHDLPN---TPGAAYLKTPS-GEITRFQTAFVSGRYDVAPVDRS MAB_3756c|M.abscessus_ATCC_199 AIGVPDAYHLPN---TPGSCYLKDDS-GELTRFQTSYVSGPYVPYGPARR Mb1812|M.bovis_AF2122/97 AAGVPNAVNLPA---QAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGVSID Rv1784|M.tuberculosis_H37Rv AAGVPNAVNLPA---QAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGVSID MMAR_2665|M.marinum_M AAGVPNAVNLPA---QAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGITVD MUL_3092|M.ulcerans_Agy99 AAGVPNAVNLPA---QAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGITVD MAV_2932|M.avium_104 AAGVPNAVNLPA---QAGLGYFRRSL-EDIVRFQAEFLWRDYFPRGISDD MLBr_01543|M.leprae_Br4923 AAGVPNAVNLPA---QAGLGYFRKSL-EDVIRFQAEFLWRDYFR-GVTLD Mvan_0413|M.vanbaalenii_PYR-1 IIGVEDAYHIESGREHKGEGFLVPAPGALPIKFRSTYVDGIYEPPRVDRS ** :* : * : :*:: :: Mflv_4959|M.gilvum_PYR-GCK QP-----------LTVRPFTSSDHDVAS---------------------- TH_2597|M.thermoresistible__bu EP-----------DAPRVFTPEPAAASA---------------------- MSMEG_1536|M.smegmatis_MC2_155 D------------HRVRPFTARPPADQL---------------------- MAB_3756c|M.abscessus_ATCC_199 TVSS-----GGGGAAPRLFTAAPVALQMRPA------------------- Mb1812|M.bovis_AF2122/97 GEEAPALVHSIDYIRPQLFTNSFTPLEVSVGGPDIEPVVAQPNGEMLESD Rv1784|M.tuberculosis_H37Rv GEEAPALVHSIDYIRPQLFTNSFTPLEVSVGGPDIEPVVAQPNGEVLESD MMAR_2665|M.marinum_M GEEAPVLVHSIDYIRPQLFTNSFTPLEVTVGGPEIDKVVAHANGEVVE-- MUL_3092|M.ulcerans_Agy99 GEEAPVLVHSIDYIRPQLFTNSFTPLEVTVGGPEIDKVVAHANGEVVE-- MAV_2932|M.avium_104 GEEAPALVHSIDYVRPQLFTNSFTPLEVSVGGPDVTVPAIPAAGADMP-- MLBr_01543|M.leprae_Br4923 GEEQPVLVHNIDYVRPQLFTNLFTPLEVSVGGPEVDAEAVFANAQEFD-- Mvan_0413|M.vanbaalenii_PYR-1 IVVHAIP-------KPQLFSAGWVDPEPD--------------------- : *: Mflv_4959|M.gilvum_PYR-GCK ------ESTVSQ---RPLLGAVLTRLAGRGAPAHRVWLPPLTSAPRLADL TH_2597|M.thermoresistible__bu ------DRMRSDGPVRTLLDTVVDRLAGHGTAAHRVWLEPLSASPPLGAL MSMEG_1536|M.smegmatis_MC2_155 ------CRSSTQ----TTLEATVARLLGHGTPAHRVWLSPLPRAIPLSDV MAB_3756c|M.abscessus_ATCC_199 EVVEDDSPAVSEATGRSVIDTILDRVEGHGNPAHEVWLPPLDDSPTLGDL Mb1812|M.bovis_AF2122/97 DIEGGEDEDEEGVRTPKVGTVIIDQLRKIKFEPYRLWQPPLTQPVAIDDL Rv1784|M.tuberculosis_H37Rv DIEGGEDEDEEGVRTPKVGTVIIDQLRKIKFEPYRLWQPPLTQPVAIDDL MMAR_2665|M.marinum_M EVEAEAE--EEGIRVPKVGTVIIDQLRRINFEPYRLWQPPLTQPVAIDDL MUL_3092|M.ulcerans_Agy99 EAEAEAEAEEEGIRVPKVGTVIIDQLRRINFEPYRLWQPPLTQPVAIDDL MAV_2932|M.avium_104 EIEGPDDDDVEGIRTPKVGTVIIDQLRKIDFQPYRLWQPPLDQPIAIDEL MLBr_01543|M.leprae_Br4923 -EEIAEEEAEGGVRTPKIGTVIIDQLRRIDFEPYRLWQPPLTQPVAIDDL Mvan_0413|M.vanbaalenii_PYR-1 TVIVDDGADVEVLPPRKLITTIGEQLAQYGPRAPQLWLPPLDEPIPLRDV . :: . .:* ** . : : Mflv_4959|M.gilvum_PYR-GCK LH----------GTPGRRLQVPIGVVDCPFEQQQMRHVVDLSGPAGNLAV TH_2597|M.thermoresistible__bu LS----------ARHGAPLTVPIGVVDCPFEQRRIPLVAALAGADGNVAV MSMEG_1536|M.smegmatis_MC2_155 LM----------ADP-EPLTAAIGLVDRPFEQRRDRLLVDLSGAAGNVVI MAB_3756c|M.abscessus_ATCC_199 IPRHG----RAGFDAVGSLTVPIGIVDRPYEQRRDPYIVDLSAAAGNVAI Mb1812|M.bovis_AF2122/97 VNRFLGRPWHKEYGSACNLVFPIGIIDRPYKHDQPPWTVDTSGPGANVLI Rv1784|M.tuberculosis_H37Rv VNRFLGRPWHKEYGSACNLVFPIGIIDRPYKHDQPPWTVDTSGPGANVLI MMAR_2665|M.marinum_M VNRFLGHPWQKEYGSARNLVFPIGVIDRPFKHDQPPWTVDTSGPGSNVLI MUL_3092|M.ulcerans_Agy99 VNWFLGHPWQKEYGSARNLVFPIGVIDRPFKHDQPPWTVDTSGPGSNVLI MAV_2932|M.avium_104 VNRFLGHPWQQDYGTARDLVFPIGIIDRPFKHDQPPWTVDTSGPGANVLI MLBr_01543|M.leprae_Br4923 VNRFLGHPWQKDYGSARNLVFPIGVIDRPFKHDQPAWTVDTSGPGSNVLV Mvan_0413|M.vanbaalenii_PYR-1 LER--------AGVGARQWRWPLGEIDRPFEMRRDPLIFDATSAAANMVI : .:* :* *:: : :.. .*: : Mflv_4959|M.gilvum_PYR-GCK AGAPRSGKSTVLSTVMTALAATHDAAAVQFYCLDFGGGELTGLQHLPHVG TH_2597|M.thermoresistible__bu VGGPQSGKSTVVRTLVMALAATHDPRDVQVYCVDCGGGALTALSALPHVG MSMEG_1536|M.smegmatis_MC2_155 VGGPQSGKSTAARTLMVALSATHDPADVQMYGLDLGGGALCALTALPHVG MAB_3756c|M.abscessus_ATCC_199 VGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYCLDFGGGTLTSLAQLPHVG Mb1812|M.bovis_AF2122/97 LGAGGSGKTTALQTLICSAALTHTPQQVQFYCLAYSSTALTTVSRIPHVG Rv1784|M.tuberculosis_H37Rv LGAGGSGKTTALQTLICSAALTHTPQQVQFYCLAYSSTALTTVSRIPHVG MMAR_2665|M.marinum_M LGAGGSGKTTALQTLISSAALTHTPDQVQFYCLAYSSTALTTVSKLPHVG MUL_3092|M.ulcerans_Agy99 LGAGGSGKTTALQTLISSAALTHTPDQVQVYCLAYSSTALTTVSKLPHVG MAV_2932|M.avium_104 LGAGGSGKTTALQTLICSAALTHTPEQVQFYCLAYSSTALTTVARLPHVG MLBr_01543|M.leprae_Br4923 LGAGGSGKTTALQTIICSAALTHTPEQVQFYCLGYSGTALTTVAHLPHVG Mvan_0413|M.vanbaalenii_PYR-1 HGGPKSGKSSALQTFVLSAAALHAPGDVSFYCLDYGGGQLRALENLAHVG *. ***: . *.: : : * . *..* : .. * : :.*** Mflv_4959|M.gilvum_PYR-GCK SVASRHEGELCRRIVAHVESVVRHRES--------ATDETWN-------- TH_2597|M.thermoresistible__bu AVAGRGDAELISRIVAVLEKILADRETRFRAAGVDSMAERRRRRQR---- MSMEG_1536|M.smegmatis_MC2_155 AVAGRRDTDLARRIVTQLHDVIRARERTFEVLGVDSMADYRARRAAGE-- MAB_3756c|M.abscessus_ATCC_199 SVASRLESDLIRRTFAEMLTIVRSRENAFRAYGIDSMAEYRRRKGAGDP- Mb1812|M.bovis_AF2122/97 EVAGPTDPYGVRRTVAELLALVRERKRSFLECGIASMEMFRRRKFGGEAG Rv1784|M.tuberculosis_H37Rv EVAGPTDPYGVRRTVAELLALVRERKRSFLECGIASMEMFRRRKFGGEAG MMAR_2665|M.marinum_M EVAGPTDPYGVRRTVAELLALVRERKRSFLEYGIASMEMFRRRKFGGEAG MUL_3092|M.ulcerans_Agy99 EVAGPTDPYGVRRTVAELLALVRERKRSFLEYGIASMEMFRRRKFGGEAG MAV_2932|M.avium_104 EVVGPTDPYGVRRTVAELLALVRERKRSFLEYGIPSMEVFRRRKFGGEPG MLBr_01543|M.leprae_Br4923 EVAGPTDPYGVRRTVAELLALVRDRKRSFLEHGIASMEVFRRRKFGGELG Mvan_0413|M.vanbaalenii_PYR-1 SVASPLEPERIRRTFGELEHLLRARQQHGAAAADGQYR------------ *.. : * . : :: *: Mflv_4959|M.gilvum_PYR-GCK -------GHVFLVVDGWATLRQD-------FDGLEPAITALAGRGLAYGV TH_2597|M.thermoresistible__bu ---DDPYGDVFLVIDGIAVIRNE-------FDTIEPRIAALAAQGLGYGV MSMEG_1536|M.smegmatis_MC2_155 -CRDDPYGDVFLVVDGWSTLRTE-------FESLESTITTLAGQGLSYGV MAB_3756c|M.abscessus_ATCC_199 QLANDPFGDVFFIIDGWSTVRQE-------FEALEPQVTALAAQGLGFGV Mb1812|M.bovis_AF2122/97 PVPDDGFGDVYLVIDNYRALAEE-------NEVLIEQVNVIINQGPSFGV Rv1784|M.tuberculosis_H37Rv PVPDDGFGDVYLVIDNYRALAEE-------NEVLIEQVNVIINQGPSFGV MMAR_2665|M.marinum_M PVPNDGFGDVYLVIDNYRALAEE-------NEVLIEQVNLIINQGPSFGV MUL_3092|M.ulcerans_Agy99 PVPNDGFGDVYLVIDNYRALAEE-------NEVLIEQVNLIINQGPSFGV MAV_2932|M.avium_104 PVPNDGFGDVYLVVDNYRALAEE-------NEVLIEQVNVIINQGPSFGV MLBr_01543|M.leprae_Br4923 PVPNDGFGDVYLVIDNYRALVEE-------NEVLIEQVNQIINQGPSFGV Mvan_0413|M.vanbaalenii_PYR-1 ----DGYGEVFLLIDNLYAFSRDNTDTFNARNPLLARVTELVNTGLSYGI *.*::::*. .. : : : : : * .:*: Mflv_4959|M.gilvum_PYR-GCK HVMIAASRWADLRPALKDQIGSRIELRLGDPAESEMDRRRARDLADRPPG TH_2597|M.thermoresistible__bu HVVVTASRWAELRPVLKDQLGTRIELRLGDPADSEMDRRRARHLIDSPPG MSMEG_1536|M.smegmatis_MC2_155 HVVVTAARWAELRPALKDQLGTRIELRLGDPAESEMDRRRARHIS-PLPG MAB_3756c|M.abscessus_ATCC_199 HTVVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKLAQLVPDGRPG Mb1812|M.bovis_AF2122/97 HVVVTADRESELRPPVRSGFGSRIELRLAAVEDAKLVRSRFAKDVPVKPG Rv1784|M.tuberculosis_H37Rv HVVVTADRESELRPPVRSGFGSRIELRLAAVEDAKLVRSRFAKDVPVKPG MMAR_2665|M.marinum_M HVVVTADRESELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPG MUL_3092|M.ulcerans_Agy99 HVVVTADRESELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPG MAV_2932|M.avium_104 HVVVTADRESELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPG MLBr_01543|M.leprae_Br4923 HVVVTADRESELRPQVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVQSG Mvan_0413|M.vanbaalenii_PYR-1 HVVVTTPNWLEVPLTMRDGLGLRLELRLHDPRDSNVR-VVSKDAALRRPA *.:::: . :: ::. :* *:**** ::.. .. Mflv_4959|M.gilvum_PYR-GCK RALTRE-------GREMAIAL------------------ADQRLPVRRDG TH_2597|M.thermoresistible__bu RGITRD-------GRELTIALPRLDEAASTTGLAASIAASAQALHIRYQQ MSMEG_1536|M.smegmatis_MC2_155 RGLTRD-------GHELLIALPRLDGTADERGLAAALTRVGEVLHTQHTG MAB_3756c|M.abscessus_ATCC_199 RGITRD-------RRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQR-SS Mb1812|M.bovis_AF2122/97 RGMVAVNYVRLDSDPQAGLHTLVARPALGSTPDNVFECDSVVAAVSRLTS Rv1784|M.tuberculosis_H37Rv RGMVAVNYVRLDSDPQAGLHTLVARPALGSTPDNVFECDSVVAAVSRLTS MMAR_2665|M.marinum_M RGMVAVNYVRLDSDPQAGLHTLVARPAMGSTPTNVFECDSVVAAVSRLTT MUL_3092|M.ulcerans_Agy99 RGMVAVNYVRLDSDPQAGLHTLVARPAMGSTPTNVFECDSVVAAVSRLTT MAV_2932|M.avium_104 RGMVAVNYVRLDADPQSGLHTLVARPALASTPDNRFESDSVVEAVSRLAT MLBr_01543|M.leprae_Br4923 RGMVAVNYVRLDSDPQAGLHTLVARPALANTPANVFESDSVVAPVSRLTS Mvan_0413|M.vanbaalenii_PYR-1 ESVPAD------------QPGRGLTMAVEHFLFAAPATESIPALNARYPG ..: : Mflv_4959|M.gilvum_PYR-GCK PGAAPVELLPAHVDRSAIA--APVP--RRGEV---LLGLGERELSAVSLD TH_2597|M.thermoresistible__bu RTAPPVELLPGRVDHETVL--AAASEVQRART---ILGLGETDLEPVTLD MSMEG_1536|M.smegmatis_MC2_155 AHAPRVRLLPRHVAGDDLV--GLRGDRPATQV---VLGIGDAELAPVAVD MAB_3756c|M.abscessus_ATCC_199 VEAPQVRMLPHKIDYAALVPQAPQNDQPNLRI---LVGINESELAPTFLE Mb1812|M.bovis_AF2122/97 AQAPPVRRLPARFGVEQVRELASRDTRQGVGAGGIAWAISELDLAPVYLN Rv1784|M.tuberculosis_H37Rv AQAPPVRRLPARFGVEQVRELASRDTRQGVGAGGIAWAISELDLAPVYLN MMAR_2665|M.marinum_M SQAPPVRRLPASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVYLN MUL_3092|M.ulcerans_Agy99 SQAPPVRRLPASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVYLN MAV_2932|M.avium_104 GQAPPVRRLPATFGLDQLRELAAQDTRQGVGAGGIAWAISELDLSPVYLN MLBr_01543|M.leprae_Br4923 AQAPPVRRLPARFGMEQVRERAVRDTRQGVGVGGIAWAISELDLQPVYLN Mvan_0413|M.vanbaalenii_PYR-1 RSAPPVRLLPTDLSPSAFPTLYPAPERVVVGQ-------REEDLAAVTVD *. *. ** . . : :* .. :: Mflv_4959|M.gilvum_PYR-GCK LTEHSHLMVLGENQCGKTASLRLLCAELV--AAPQE------------AR TH_2597|M.thermoresistible__bu LTEQPHLVMLGDPRSGKTAALRTVCREILRTHSPTA------------AQ MSMEG_1536|M.smegmatis_MC2_155 FAEQSDLVILGDAGCGKSTALRALCDRLVRTNDPSA------------VQ MAB_3756c|M.abscessus_ATCC_199 FGEQPHMMIFGDSECGKTALLRTMCREIVRTTTPQQ------------AQ Mb1812|M.bovis_AF2122/97 FAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGASSAPPPAPGRPSAQ Rv1784|M.tuberculosis_H37Rv FAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGASSAPPPAPGRPSAQ MMAR_2665|M.marinum_M FAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPSAQ MUL_3092|M.ulcerans_Agy99 FAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPSAQ MAV_2932|M.avium_104 FDENAHLMVTGRRECGRTTTLATIMKEIGRLYAPGASSAPTPPAGQPSAQ MLBr_01543|M.leprae_Br4923 FAENAHLMITGRRECGRTTVLATIMSEIGRLYAPGGTSAPPTS--ERSAQ Mvan_0413|M.vanbaalenii_PYR-1 FGDNPLMMVFGDAKTGKTTLLRHLIRTIRENSRPDQ------------VA : ::. ::: * *::: * : : * . Mflv_4959|M.gilvum_PYR-GCK LEIVDFRRTLLGAVDSDRLTGYAVTPAAVTSRVAAITGVLADRMPGEDVT TH_2597|M.thermoresistible__bu LLLVDFRRTLLGVVETEHLGAYAMSPPTLQTALAGLVDRLRARLPDAAVT MSMEG_1536|M.smegmatis_MC2_155 LLVVDYRREMLDAVGSDHLRGYAVSAGALETAVADLIRTLRERMPGPDIA MAB_3756c|M.abscessus_ATCC_199 LFIVDYRRTLLGVVETEHLAKYAMSSNTLVDEVPALIELLKSRMPGPDVT Mb1812|M.bovis_AF2122/97 VWLVDPRRQLLTALGSDYVERFAYNLDGVVAMMGELAAALAGREPPPGLS Rv1784|M.tuberculosis_H37Rv VWLVDPRRQLLTALGSDYVERFAYNLDGVVAMMGELAAALAGREPPPGLS MMAR_2665|M.marinum_M VWLIDPRRQLLTALGSNYVERFAYNLDGVQAMMGELAAVLAGREPPPGLS MUL_3092|M.ulcerans_Agy99 VWLIDPRRQLLTALGSNYVERFAYNLDGVQAKMGELAAVLAGREPPPGLS MAV_2932|M.avium_104 VWLVDPRRQLLTTLGSDYVEKFAYNLDGVQAMMGELAAALAGREPPPGLS MLBr_01543|M.leprae_Br4923 VWLIDPRRQLLTMLGSNYMEKFAYNLDGVSAMVGELAALLASREPPPDLS Mvan_0413|M.vanbaalenii_PYR-1 FTVIDRRLQLVDEPIFP-DNEYTPNIDRITPAMLGLSALLEKRRPPAGLS . ::* * :: :: . : : : * * * :: Mflv_4959|M.gilvum_PYR-GCK QRQLRDRSWWHGPE------IYVVIDDYDLVAGA--------TGNPLTPL TH_2597|M.thermoresistible__bu QRQLRDRSWWTGPE------LFLVIDDYDLVAES--------AAAALTPV MSMEG_1536|M.smegmatis_MC2_155 PRQLRERTWWTGPE------LYVVVDDYDLVAAG--------AGNPLTSL MAB_3756c|M.abscessus_ATCC_199 QQELRDRSWWSGPE------IYILVDDYDLVALA--------SGNPLLPL Mb1812|M.bovis_AF2122/97 AEELLSRSWWSGPE------IFLIVDDIQQLPPG--------FDSPLHKA Rv1784|M.tuberculosis_H37Rv AEELLSRSWWSGPE------IFLIVDDIQQLPPG--------FDSPLHKA MMAR_2665|M.marinum_M AEELLSRSWWSGPE------IFLIVDDIQQLPPG--------FDSPLHKA MUL_3092|M.ulcerans_Agy99 AEELLSRSWWSGPE------IFLIVDDIQQLPPG--------FDSPLHKA MAV_2932|M.avium_104 AEELLSRNWWSGPE------IFLIVDDIQQLPAG--------FDSPLHKA MLBr_01543|M.leprae_Br4923 AEELLSRSWWSGPE------IFLIIDDIQQLPPS--------FDSPLQKV Mvan_0413|M.vanbaalenii_PYR-1 PQELSRWDFRAGANGSGRHLHYLIIDDVDQIPDGPAISGPFAGQRPWTAL .:* : *.: ::::** : :. . . Mflv_4959|M.gilvum_PYR-GCK ADFLPHARDLGLHVVVARRSGGAARAMF-DPLLARMRDMGCAGLMMSANA TH_2597|M.thermoresistible__bu TELLPHGRDIGLHVIVARRAGGAARAMF-DPLPARLRETGAAGLMLSAPP MSMEG_1536|M.smegmatis_MC2_155 LDFVPHARDLGLHLVIARRSGGAARAMF-DPVLSRLKELGCMGLMMSASP MAB_3756c|M.abscessus_ATCC_199 AEYLPHSKDIGLHVVIARRTSGASRAMF-EPMMARMKDLSCIGLQMSGNK Mb1812|M.bovis_AF2122/97 VPFVNRAADVGLHVIVTRTFGGWSSAGS-DPMLRALHQANAPLLVMDADP Rv1784|M.tuberculosis_H37Rv VPFVNRAADVGLHVIVTRTFGGWSSAGS-DPMLRALHQANAPLLVMDADP MMAR_2665|M.marinum_M APWVNRAADVGLHVIVTRSFGGWSSAGS-DPMLRALHQANAPLLVMDADP MUL_3092|M.ulcerans_Agy99 APWVNRAADVGLHVIVTRSFGGWSSAGS-DPMLRALHQANAPLLVMDADP MAV_2932|M.avium_104 APWVTRAADVGLHVIVTRTFGGWSSAGS-DPMLRALAQANAPLLVMDADP MLBr_01543|M.leprae_Br4923 VPWVTRAGDVGLHVIATRTFGGWSSAGS-DPMLRALHQANAPLLVMDADP Mvan_0413|M.vanbaalenii_PYR-1 IGLLAQASDLGLRVIVTARAAGSAHAVMTAPLLRRLNDLQATTFLLSGNP : :. *:**::: : .* : * *: : : . : :.. Mflv_4959|M.gilvum_PYR-GCK EDGVLLGAVRPGRLPPGRGTLIAR---GRPDELLQVAWTDPP-------- TH_2597|M.thermoresistible__bu EEGQLWGSVRATPLPPGRATLLTR---GRPAQLIQVSWIEPP-------- MSMEG_1536|M.smegmatis_MC2_155 DEGVLLGSVRPRPLPPGRGTLLTR---SGPEQLIQVALPCDVS------- MAB_3756c|M.abscessus_ATCC_199 DEGVLLGTVRPSEQPPGRGTLVMR---SGGQQLIQVAWSEPQ-------- Mb1812|M.bovis_AF2122/97 DEGFIRGKMKGGPLPRGRGLLMAE---DTG-VFVQVAATEVRR------- Rv1784|M.tuberculosis_H37Rv DEGFIRGKMKGGPLPRGRGLLMAE---DTG-VFVQVAATEVRR------- MMAR_2665|M.marinum_M DEGFIRGKMKGGPLPRGRGLLMAE---DTG-VFVQVALTEVRK------- MUL_3092|M.ulcerans_Agy99 DEGFIRGKMKGGPLPRGRGLLMAE---DTG-VFVQVALTEVRK------- MAV_2932|M.avium_104 DEGFIRGKMKGGPLPRGRGLLMAE---DTG-VFVQVAATEFRK------- MLBr_01543|M.leprae_Br4923 DEGFIRGKMKGGPLPRGRGLLMAE---DTG-VLVQVAETDMRR------- Mvan_0413|M.vanbaalenii_PYR-1 ADSGKIRGHRFARLPVGRAMLLDDRNSSGSPTFVQLVNPLAERTAARSGH :. : * **. *: . ::*: Mflv_4959|M.gilvum_PYR-GCK ------ TH_2597|M.thermoresistible__bu ------ MSMEG_1536|M.smegmatis_MC2_155 ------ MAB_3756c|M.abscessus_ATCC_199 ------ Mb1812|M.bovis_AF2122/97 ------ Rv1784|M.tuberculosis_H37Rv ------ MMAR_2665|M.marinum_M ------ MUL_3092|M.ulcerans_Agy99 ------ MAV_2932|M.avium_104 ------ MLBr_01543|M.leprae_Br4923 ------ Mvan_0413|M.vanbaalenii_PYR-1 SGKEYS