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MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGWLMALYSFFRR SSKPLDTPSEPVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHLLSV HCPDLEAVVVSAGYRVGHVASLDVVNLYQQVIGADPAPAHRRTWIMLRADPVRTRKSAQRRDAGVAGLAR YLIASTTRIADQLASHGVDAVCGHSFESVDHATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARAD HTITRVRVAPGKTPQATVVLTTLGKPKTPCGFYRLHGAQQPALLGRSFVAYQHCQMPIGSAGVLVGETVN RCSVYMPFDDVDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLD PYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00042 | - | - | 100% (467) | hypothetical protein MLBr_00042 |
| M. leprae Br4923 | MLBr_01537 | - | 3e-05 | 24.03% (233) | putative secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3912c | - | 0.0 | 72.29% (462) | hypothetical protein Mb3912c |
| M. gilvum PYR-GCK | Mflv_0756 | - | 1e-157 | 58.59% (454) | hypothetical protein Mflv_0756 |
| M. tuberculosis H37Rv | Rv3882c | - | 0.0 | 72.29% (462) | hypothetical protein Rv3882c |
| M. abscessus ATCC 19977 | MAB_3760 | - | 2e-18 | 22.00% (441) | hypothetical protein MAB_3760 |
| M. marinum M | MMAR_5458 | - | 0.0 | 67.74% (465) | hypothetical protein MMAR_5458 |
| M. avium 104 | MAV_0159 | - | 1e-15 | 26.11% (383) | hypothetical protein MAV_0159 |
| M. smegmatis MC2 155 | MSMEG_0082 | - | 1e-152 | 55.85% (453) | hypothetical protein MSMEG_0082 |
| M. thermoresistible (build 8) | TH_1275 | - | 1e-161 | 58.91% (460) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0091 | - | 1e-160 | 60.35% (454) | hypothetical protein Mvan_0091 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3912c|M.bovis_AF2122/97 ----MRNPLG---LRFSTGHALLASALAPPCIIAFLETRY-WWAGIALAS
Rv3882c|M.tuberculosis_H37Rv ----MRNPLG---LRFSTGHALLASALAPPCIIAFLETRY-WWAGIALAS
MMAR_5458|M.marinum_M ----MRNPFSSIRFRVSTGHTLVVAVLAPPCIMMFLHMRY-WWVGIALVA
MLBr_00042|M.leprae_Br4923 ----MRNPVW---LRFSMGRALLVTALVPPCIILFFHTQY-WWAGIALVV
MSMEG_0082|M.smegmatis_MC2_155 ----MNFLR-QFGFRFTTGHGIWAATLIPACIAICMHFDL-LWLGITLGA
TH_1275|M.thermoresistible__bu ----MKSLRNLFGMRFSTGHGIWAAVLIPAVVVLFERLEM-LWLGVVVAV
Mflv_0756|M.gilvum_PYR-GCK ----MSRFLSIFGVRFTTGHALWAAVLVPACILIFAQLNL-LWLGITLAV
Mvan_0091|M.vanbaalenii_PYR-1 ----MSRFASIFGLRFTTGHALWAAALIPACILVFARLEL-LWLGITLGV
MAB_3760|M.abscessus_ATCC_1997 MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISLLFGWPWWAALLIAI
MAV_0159|M.avium_104 ------------MRPNLTGFSRGSNRRVVGVWVVFVLALASWLLGGYIAA
. :
Mb3912c|M.bovis_AF2122/97 LGVIVATVTFYGRRITGWVAAVYAWLRRRRRPPDSSSEPVVGATVKPGDH
Rv3882c|M.tuberculosis_H37Rv LGVIVATVTFYGRRITGWVAAVYAWLRRRRRPPDSSSEPVVGATVKPGDH
MMAR_5458|M.marinum_M LGVIVATVTFSGRRVTGWVATVFAWLRRRRRPPDVPSEPVVGATVKPGDH
MLBr_00042|M.leprae_Br4923 LVVILTLVEFSGRWLSGWLMALYSFFRRSSKPLDTPSEPVIGATVKPADQ
MSMEG_0082|M.smegmatis_MC2_155 LIALFSVLTIRGLRITGWVRAIFSWRRRHRSTPDIASEPAVGSTVMPGDH
TH_1275|M.thermoresistible__bu FIAPASVLTIRGRRLTGWVAAVFSWRRRHRVPPARPSEPAVGATVAPGDH
Mflv_0756|M.gilvum_PYR-GCK LIALCALVTIRGRRITGWIAALFAWRRRHRQPPPAPSEPAVGATVVPGDH
Mvan_0091|M.vanbaalenii_PYR-1 LIGLASVVTIRGRRLTGWVAALFAWRRRHRQPPPTPSEPAVGATVIPGDH
MAB_3760|M.abscessus_ATCC_1997 VSLALVLGRWGGQTVRHWAVTGFKYLTGRTYR---SSGSIADTPSGQDSW
MAV_0159|M.avium_104 AVAVLVGVALVFVRWWGQPAWSWAVLWRRGRRPIDWSAPITVANNRSG--
: * . :
Mb3912c|M.bovis_AF2122/97 VAVRWQGEFLVAVIELIPRPFTPTVIVD-GQAHTDDMLDTGLVEELLSVH
Rv3882c|M.tuberculosis_H37Rv VAVRWQGEFLVAVIELIPRPFTPTVIVD-GQAHTDDMLDTGLVEELLSVH
MMAR_5458|M.marinum_M VAVRWRRDHLIAVIELKPRPFTPTVIVD-GKAHTDDVLDTRLLEDLLSVH
MLBr_00042|M.leprae_Br4923 VIMRWQDGFLVSVVELIPRPFTPTVIVD-GEAQTDDLLETQLLEHLLSVH
MSMEG_0082|M.smegmatis_MC2_155 VAVRWQGDYLIAVIELVPRPFTPTVIVN-GSAMTDDVVNTKLVERLLEAH
TH_1275|M.thermoresistible__bu VAVRWQGDHLVSAIELVPRPFTPTVLVN-GKAFTDDLLDTRLVEQLLTAH
Mflv_0756|M.gilvum_PYR-GCK VALRWQHGYLVSAIELIPRPFTPTVIVN-GEAFTDDVIDSRQLEKLLAAY
Mvan_0091|M.vanbaalenii_PYR-1 VALRWQDDYLVSVIELVPRPFTPTVIVN-GEAFTDDVVETRLVEDLLTAY
MAB_3760|M.abscessus_ATCC_1997 TGTRWENGKLITVLEISATQRHPSVITP-DHCATDSLVPLRVLRECMHQN
MAV_0159|M.avium_104 GGVRVQDGVAVVAVQLLGRAHRATLVTGSVTVETENVLDVVELAPMLHQA
* . : .::: .:::. *:.:: : :
Mb3912c|M.bovis_AF2122/97 C-PDLE-ADIVSAGYRVGNTAAPDVVSLYQQVIGTDPAPANRRTWIVLRA
Rv3882c|M.tuberculosis_H37Rv C-PDLE-ADIVSAGYRVGNTAAPDVVSLYQQVIGTDPAPANRRTWIVLRA
MMAR_5458|M.marinum_M C-PDLE-ADVVSAGYRVGNTASEEVVSLYQRVIGADPAPANRRTWIMLRA
MLBr_00042|M.leprae_Br4923 C-PDLE-AVVVSAGYRVGHVASLDVVNLYQQVIGADPAPAHRRTWIMLRA
MSMEG_0082|M.smegmatis_MC2_155 C-PDLE-ADVVSAGYRVGKTAPASLIALYEQVVGPYPAPANRRTWIVLRA
TH_1275|M.thermoresistible__bu C-PDLE-ADIVSAGYRVGKTAPASLLALYEQVLGPYPAPANRRTWIVLRA
Mflv_0756|M.gilvum_PYR-GCK C-PDLE-ADIVSAGYRVGRTAPAALVGLYEQVVGPYPAPARRRTWIVLRA
Mvan_0091|M.vanbaalenii_PYR-1 C-PDLE-ADIVSAGYRVGKTAPAALVALYEQVVGPYPAPASRRTWIVLRA
MAB_3760|M.abscessus_ATCC_1997 D-IELESIDVISNGQRT--AQGTVLRGGYDRLVGPLPAVAIRTVWVVLRF
MAV_0159|M.avium_104 LGLQLDSISVVTVGSRHG--NVGDYPRVYDSEIGTPPYAGRRETWLIMRL
:*: ::: * * *: :*. * . * .*:::*
Mb3912c|M.bovis_AF2122/97 DPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDAVCGRSFDDY
Rv3882c|M.tuberculosis_H37Rv DPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDAVCGRSFDDY
MMAR_5458|M.marinum_M DPEQTRKSAQRREAGLAGLARYLVASATRIADGLASNGVDAVCGRSFDDY
MLBr_00042|M.leprae_Br4923 DPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESV
MSMEG_0082|M.smegmatis_MC2_155 DPEKTQRSAHRRDSGVSGLARYLVASATRIADQLASNGVDARCCRSFDDY
TH_1275|M.thermoresistible__bu DPERTQKSARRRDVGVAGLSRYLVASTTRIADQLASHGVDARCARSFDDL
Mflv_0756|M.gilvum_PYR-GCK DPDKTRKSALRRDVGVSGLAQYVVSSTTRIADHLASNGIDARPARSFDDF
Mvan_0091|M.vanbaalenii_PYR-1 DPDKTRKSALRRNEGVAGLAQYLVSSTTRIADHLASKGVDARPARSFDDF
MAB_3760|M.abscessus_ATCC_1997 DPGANVDAVFRRGGGRRGAERCAVIATARVRRALAAAHCASTILQAGQIH
MAV_0159|M.avium_104 AVIDNAQALRWR----TTVGAAAISVAQRIAGLLRCQGLRAKVANATDLA
. : * : : *: * . : .: :
Mb3912c|M.bovis_AF2122/97 DHATDIGFVREK-----WSMIKGRD--AYTAAYA----APGGPDVWWSAR
Rv3882c|M.tuberculosis_H37Rv DHATDIGFVREK-----WSMIKGRD--AYTAAYA----APGGPDVWWSAR
MMAR_5458|M.marinum_M DRATDIGYVREK-----WSMIKGAD--SYTAAYT----APGGPDLWWSAR
MLBr_00042|M.leprae_Br4923 DHATDVGFMQEK-----WSMMRGQN--AYSVAYT----APAGPDAWWSAR
MSMEG_0082|M.smegmatis_MC2_155 EKATEISYERET-----WSSIKGRS--TFTAAYT----APGGPDMWWSAR
TH_1275|M.thermoresistible__bu DRATEISFERET-----WSSIKGRS--TFTAAYS----APGGPDVWWSAR
Mflv_0756|M.gilvum_PYR-GCK DGATEISFERET-----WSMVKGRS--TFTAAYH----APGGPDVWWSAR
Mvan_0091|M.vanbaalenii_PYR-1 DRATEISFERET-----WSMVKGRS--TFTAAYH----APGGPDVWWSAR
MAB_3760|M.abscessus_ATCC_1997 RISAEMLRQYAG-----APMHEDWSGLTLIDSYN----VAMGIDPWYIT-
MAV_0159|M.avium_104 ELDRRLGWDAVSGTVQRWKAIRGEAGWMTTYAYPPQAITSRNLSQAWTLR
: .. :* .. . . :
Mb3912c|M.bovis_AF2122/97 ADHTITRVRVAPGMAPQSTVLLTTADKPKTPR------------------
Rv3882c|M.tuberculosis_H37Rv ADHTITRVRVAPGMAPQSTVLLTTADKPKTPR------------------
MMAR_5458|M.marinum_M ADHTITRVRIAPGMPPRSTVLLTTVGKPKTPR------------------
MLBr_00042|M.leprae_Br4923 ADHTITRVRVAPGKTPQATVVLTTLGKPKTPC------------------
MSMEG_0082|M.smegmatis_MC2_155 ADHTITRVRVRPGAAPSSAILLTTLANPTTPR------------------
TH_1275|M.thermoresistible__bu ADHTITRLRVRPGAPPTSTVLLTTLANPTTPR------------------
Mflv_0756|M.gilvum_PYR-GCK ADYTLTRVRIVPGAAPTATVLLTTLANPSTPR------------------
Mvan_0091|M.vanbaalenii_PYR-1 ADHTLTRMRIVPGSAPTTTVLLTTLANPSTPR------------------
MAB_3760|M.abscessus_ATCC_1997 -DATLTGLWARPTLETSVTVRLRPAAKGRTSVGALVRWATDEQLPVRHST
MAV_0159|M.avium_104 ADEVIQNVTVYPDGHCSATITVRTPTPAPTPP-----------------S
* .: : * :: : . *.
Mb3912c|M.bovis_AF2122/97 GFARLFGGQRPALQGQHLVANR-----------------HCQLPIGSAGV
Rv3882c|M.tuberculosis_H37Rv GFARLFGGQRPALQGQHLVANR-----------------HCQLPIGSAGV
MMAR_5458|M.marinum_M GFSRLFGSQRPALEGQTLVANH-----------------HCQLPIGSAGV
MLBr_00042|M.leprae_Br4923 GFYRLHGAQQPALLGRSFVAYQ-----------------HCQMPIGSAGV
MSMEG_0082|M.smegmatis_MC2_155 GFSCLFGGQRAALQGIVPVSDK-----------------HYDLPIGSAGV
TH_1275|M.thermoresistible__bu GFSCLFGGQRAALEGLSPVTDK-----------------HHELPIGSAGV
Mflv_0756|M.gilvum_PYR-GCK GFSCLYGGQRAALLGESPVTDR-----------------HYELPIGSAGV
Mvan_0091|M.vanbaalenii_PYR-1 GFSCLFGGQRAALLGENPVTDR-----------------HYELPIGSAGV
MAB_3760|M.abscessus_ATCC_1997 GMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEMSNEELDGIHLPTSGCGQ
MAV_0159|M.avium_104 VILRRLNGEQAAAAAANMCGPRPHLRG----LRRSRLPAELITEIGPSGV
: ..:: * . . .*
Mb3912c|M.bovis_AF2122/97 LVGETVNRCPVYMPFDD---VDIALNLGDAQTFTQFVVRAAAAGAMVTVG
Rv3882c|M.tuberculosis_H37Rv LVGETVNRCPVYMPFDD---VDIALNLGDAQTFTQFVVRAAAAGAMVTVG
MMAR_5458|M.marinum_M LIGETVNRRPVYMPFDD---VDATVNLGDAQTFTQFAVRSAAAGGVVTVG
MLBr_00042|M.leprae_Br4923 LVGETVNRCSVYMPFDD---VDVSVSLGDVQTFTQFVVRAAAAGGIVTLG
MSMEG_0082|M.smegmatis_MC2_155 LVGETADRYPVYMPFDN---VDVSINLGDARLFTQFVIRSAAAGAVVTLG
TH_1275|M.thermoresistible__bu LVGETVDRYPVYMPFDD---VDVSINLGDARLFTQFVVRSAAAGGVVTLL
Mflv_0756|M.gilvum_PYR-GCK LVGETADRYPVYMPFDD---TDVSINLGNARLFTQFVVRSAAAGANVTLQ
Mvan_0091|M.vanbaalenii_PYR-1 LVGETADRYPVYMPFDD---VDVSINLGNARLFTQFVVRSAAAGAAVTLQ
MAB_3760|M.abscessus_ATCC_1997 LIGSDMSGRAIATRLSGQ-GVHTVVVRAELYVCQQVVLRAVAIGALVVVY
MAV_0159|M.avium_104 LIGKLPNGDRLLMPVTDAGELSRVFVAADDPIAKRIVIRTAGAGERVCVH
*:*. . : . . . .: :..:*:.. * * :
Mb3912c|M.bovis_AF2122/97 P---------QFEEFARLIGAHIGQEVKVAWPNATTYLGP----------
Rv3882c|M.tuberculosis_H37Rv P---------QFEEFARLIGAHIGQEVKVAWPNATTYLGP----------
MMAR_5458|M.marinum_M P---------HFEQFAGLIGAHVGAEAKVVWPNATTYLGA----------
MLBr_00042|M.leprae_Br4923 Q---------QFEKFARMIGGQIGSVAKVAWPNATTYLDP----------
MSMEG_0082|M.smegmatis_MC2_155 P---------QFREFATMINGRVGRTPRIGWPNATTYLGP----------
TH_1275|M.thermoresistible__bu P---------QFREFASLINARVGPEAKISWPNATTYLGP----------
Mflv_0756|M.gilvum_PYR-GCK P---------QFGEFAGYVNAQIGPTAKVAWPHATTYLRP----------
Mvan_0091|M.vanbaalenii_PYR-1 P---------QFEEFAGFVNARIGQVAKVAWPHATTYLRP----------
MAB_3760|M.abscessus_ATCC_1997 T---------DRPHMWDVMVTSIGDANRIQFASGPGFIDPRCTLAVVDGM
MAV_0159|M.avium_104 TRDMSRWVSVRMPEISVVNSSRPAPRTTVSVVEYAPRRGEGVEAAISPTP
.: . : .
Mb3912c|M.bovis_AF2122/97 ---------------------HPGIDRVILR------HNVIGTPRHRQLP
Rv3882c|M.tuberculosis_H37Rv ---------------------HPGIDRVILR------HNVIGTPRHRQLP
MMAR_5458|M.marinum_M ---------------------HPGIDRVILR------HNLVGTPRHRKLP
MLBr_00042|M.leprae_Br4923 ---------------------YPGSERVILK------HDIIGTPRHRKLP
MSMEG_0082|M.smegmatis_MC2_155 ---------------------HQGVGRVILR------PNFIDTPRHRQLP
TH_1275|M.thermoresistible__bu ---------------------HPGIGRVILR------HNFIDTPRHRQLP
Mflv_0756|M.gilvum_PYR-GCK ---------------------QPGVGRVVLR------DNFIATPRHKELP
Mvan_0091|M.vanbaalenii_PYR-1 ---------------------HPGVGRVMLR------DDFIATPRHKQLP
MAB_3760|M.abscessus_ATCC_1997 QPTALPSNCTALHIISSEYDALPARPDVIIDQPNGYGDHILLTAGGETIQ
MAV_0159|M.avium_104 RPATVITVAPAG--TTLSEAQRHGFEVIIEQVSP---AVVNVSAAGKNWL
. :: . :. .
Mb3912c|M.bovis_AF2122/97 IRRVSPPEESRYQMALPK------
Rv3882c|M.tuberculosis_H37Rv IRRVSPPEESRYQMALPK------
MMAR_5458|M.marinum_M IRRVSPPEESRFQMALPK------
MLBr_00042|M.leprae_Br4923 IRRISPPEEGHYQMVLPKSSYEL-
MSMEG_0082|M.smegmatis_MC2_155 IQLINPREESRYQMALEQ------
TH_1275|M.thermoresistible__bu IRLINPREESRYQMALEG------
Mflv_0756|M.gilvum_PYR-GCK IRLINPREESRYQMALEP------
Mvan_0091|M.vanbaalenii_PYR-1 IRLINPREESRYQMVLEP------
MAB_3760|M.abscessus_ATCC_1997 VRLVTVSDELAYLGRPIQAFAQ--
MAV_0159|M.avium_104 VEMDMFRAEHRYVSLEPVSMSVGM
:. * :