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M. thermoresistible (build 8) TH_1275 ()

annotation: POSSIBLE CONSERVED MEMBRANE PROTEIN
coordinates: 2430180 - 2431577
length: 466

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1275-100% (466)POSSIBLE CONSERVED MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3912c-0.069.57% (460) hypothetical protein Mb3912c
M. gilvum PYR-GCKMflv_0756-0.075.86% (464) hypothetical protein Mflv_0756
M. tuberculosis H37RvRv3882c-0.069.57% (460) hypothetical protein Rv3882c
M. leprae Br4923MLBr_00042-1e-16258.91% (460) hypothetical protein MLBr_00042
M. abscessus ATCC 19977MAB_3760-3e-1823.90% (456) hypothetical protein MAB_3760
M. marinum MMMAR_5458-0.066.74% (463) hypothetical protein MMAR_5458
M. avium 104MAV_0159-1e-1425.87% (429) hypothetical protein MAV_0159
M. smegmatis MC2 155MSMEG_0082-0.080.09% (457) hypothetical protein MSMEG_0082
M. ulcerans Agy99MUL_3078-2e-0925.00% (340) hypothetical protein MUL_3078
M. vanbaalenii PYR-1Mvan_0091-0.078.88% (464) hypothetical protein Mvan_0091

CLUSTAL 2.0.9 multiple sequence alignment


Mb3912c|M.bovis_AF2122/97           ----MRNPLG---LRFSTGHALLASALAPPCIIAFLETRY----WWAGIA
Rv3882c|M.tuberculosis_H37Rv        ----MRNPLG---LRFSTGHALLASALAPPCIIAFLETRY----WWAGIA
MMAR_5458|M.marinum_M               ----MRNPFSSIRFRVSTGHTLVVAVLAPPCIMMFLHMRY----WWVGIA
MLBr_00042|M.leprae_Br4923          ----MRNPVW---LRFSMGRALLVTALVPPCIILFFHTQY----WWAGIA
TH_1275|M.thermoresistible__bu      ----MKSLRNLFGMRFSTGHGIWAAVLIPAVVVLFERLEM----LWLGVV
MSMEG_0082|M.smegmatis_MC2_155      ----MNFLR-QFGFRFTTGHGIWAATLIPACIAICMHFDL----LWLGIT
Mflv_0756|M.gilvum_PYR-GCK          ----MSRFLSIFGVRFTTGHALWAAVLVPACILIFAQLNL----LWLGIT
Mvan_0091|M.vanbaalenii_PYR-1       ----MSRFASIFGLRFTTGHALWAAALIPACILVFARLEL----LWLGIT
MAB_3760|M.abscessus_ATCC_1997      MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISLLFGWP---WWAALL
MUL_3078|M.ulcerans_Agy99           MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVG
MAV_0159|M.avium_104                ------MRPNLTGFSRGSNRRVVGVWVVFVLALASWLLGG----YIAAAV
                                                         :    :                    .  

Mb3912c|M.bovis_AF2122/97           LASLGVIVATVTFYGRRITG-WVAAVYAWLRRRRRPPDSSSEPVVGATVK
Rv3882c|M.tuberculosis_H37Rv        LASLGVIVATVTFYGRRITG-WVAAVYAWLRRRRRPPDSSSEPVVGATVK
MMAR_5458|M.marinum_M               LVALGVIVATVTFSGRRVTG-WVATVFAWLRRRRRPPDVPSEPVVGATVK
MLBr_00042|M.leprae_Br4923          LVVLVVILTLVEFSGRWLSG-WLMALYSFFRRSSKPLDTPSEPVIGATVK
TH_1275|M.thermoresistible__bu      VAVFIAPASVLTIRGRRLTG-WVAAVFSWRRRHRVPPARPSEPAVGATVA
MSMEG_0082|M.smegmatis_MC2_155      LGALIALFSVLTIRGLRITG-WVRAIFSWRRRHRSTPDIASEPAVGSTVM
Mflv_0756|M.gilvum_PYR-GCK          LAVLIALCALVTIRGRRITG-WIAALFAWRRRHRQPPPAPSEPAVGATVV
Mvan_0091|M.vanbaalenii_PYR-1       LGVLIGLASVVTIRGRRLTG-WVAALFAWRRRHRQPPPTPSEPAVGATVI
MAB_3760|M.abscessus_ATCC_1997      IAIVSLALVLGRWGGQTVRH-WAVTGFKYLTGRTYR---SSGSIADTPSG
MUL_3078|M.ulcerans_Agy99           IAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRR
MAV_0159|M.avium_104                AVLVGVALVFVRWWGQPAWS------WAVLWRRGRRPIDWSAPITVANNR
                                       .          *           :             . .       

Mb3912c|M.bovis_AF2122/97           PG-DHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEEL
Rv3882c|M.tuberculosis_H37Rv        PG-DHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEEL
MMAR_5458|M.marinum_M               PG-DHVAVRWRRDHLIAVIELKPRPFTPTVIVDGKAHTDDVLDTRLLEDL
MLBr_00042|M.leprae_Br4923          PA-DQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHL
TH_1275|M.thermoresistible__bu      PG-DHVAVRWQGDHLVSAIELVPRPFTPTVLVNGKAFTDDLLDTRLVEQL
MSMEG_0082|M.smegmatis_MC2_155      PG-DHVAVRWQGDYLIAVIELVPRPFTPTVIVNGSAMTDDVVNTKLVERL
Mflv_0756|M.gilvum_PYR-GCK          PG-DHVALRWQHGYLVSAIELIPRPFTPTVIVNGEAFTDDVIDSRQLEKL
Mvan_0091|M.vanbaalenii_PYR-1       PG-DHVALRWQDDYLVSVIELVPRPFTPTVIVNGEAFTDDVVETRLVEDL
MAB_3760|M.abscessus_ATCC_1997      QD-SWTGTRWENGKLITVLEISATQRHPSVITPDHCATDSLVPLRVLREC
MUL_3078|M.ulcerans_Agy99           FGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAEN
MAV_0159|M.avium_104                SG---GGVRVQDGVAVVAVQLLGRAHRATLVTGSVTVETENVLDVVELAP
                                            * .    : .: :      .:            :        

Mb3912c|M.bovis_AF2122/97           LSVHCPDLE-ADIVSAGYRVGNTAAPDVVSLYQQ------VIGTDPAPAN
Rv3882c|M.tuberculosis_H37Rv        LSVHCPDLE-ADIVSAGYRVGNTAAPDVVSLYQQ------VIGTDPAPAN
MMAR_5458|M.marinum_M               LSVHCPDLE-ADVVSAGYRVGNTASEEVVSLYQR------VIGADPAPAN
MLBr_00042|M.leprae_Br4923          LSVHCPDLE-AVVVSAGYRVGHVASLDVVNLYQQ------VIGADPAPAH
TH_1275|M.thermoresistible__bu      LTAHCPDLE-ADIVSAGYRVGKTAPASLLALYEQ------VLGPYPAPAN
MSMEG_0082|M.smegmatis_MC2_155      LEAHCPDLE-ADVVSAGYRVGKTAPASLIALYEQ------VVGPYPAPAN
Mflv_0756|M.gilvum_PYR-GCK          LAAYCPDLE-ADIVSAGYRVGRTAPAALVGLYEQ------VVGPYPAPAR
Mvan_0091|M.vanbaalenii_PYR-1       LTAYCPDLE-ADIVSAGYRVGKTAPAALVALYEQ------VVGPYPAPAS
MAB_3760|M.abscessus_ATCC_1997      MHQNDIELESIDVISNGQRT--AQGTVLRGGYDR------LVGPLPAVAI
MUL_3078|M.ulcerans_Agy99           LRQFDVQLDGVDIMTVEVRGGAEAARASASLDEWGPEEWGMVGESPAANR
MAV_0159|M.avium_104                MLHQALGLQLDSISVVTVGSRHGNVGDYPRVYDS------EIGTPPYAGR
                                    :      *:   :                   :        :*  *    

Mb3912c|M.bovis_AF2122/97           RRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDA
Rv3882c|M.tuberculosis_H37Rv        RRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDA
MMAR_5458|M.marinum_M               RRTWIMLRADPEQTRKSAQRREAGLAGLARYLVASATRIADGLASNGVDA
MLBr_00042|M.leprae_Br4923          RRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDA
TH_1275|M.thermoresistible__bu      RRTWIVLRADPERTQKSARRRDVGVAGLSRYLVASTTRIADQLASHGVDA
MSMEG_0082|M.smegmatis_MC2_155      RRTWIVLRADPEKTQRSAHRRDSGVSGLARYLVASATRIADQLASNGVDA
Mflv_0756|M.gilvum_PYR-GCK          RRTWIVLRADPDKTRKSALRRDVGVSGLAQYVVSSTTRIADHLASNGIDA
Mvan_0091|M.vanbaalenii_PYR-1       RRTWIVLRADPDKTRKSALRRNEGVAGLAQYLVSSTTRIADHLASKGVDA
MAB_3760|M.abscessus_ATCC_1997      RTVWVVLRFDPGANVDAVFRRGGGRRGAERCAVIATARVRRALAAAHCAS
MUL_3078|M.ulcerans_Agy99           RRTWLILRMNPQRNVAAIASRDS----LASTLVTATERLAQVLDGQSCAA
MAV_0159|M.avium_104                RETWLIMRLAVIDNAQALRWRTT----VGAAAISVAQRIAGLLRCQGLRA
                                    * .*:::*     .  :   *           :  : *:   *      :

Mb3912c|M.bovis_AF2122/97           VCGRSFDDYDHATDIGFVREKWSMIKGRD-----------AYTAAYAAPG
Rv3882c|M.tuberculosis_H37Rv        VCGRSFDDYDHATDIGFVREKWSMIKGRD-----------AYTAAYAAPG
MMAR_5458|M.marinum_M               VCGRSFDDYDRATDIGYVREKWSMIKGAD-----------SYTAAYTAPG
MLBr_00042|M.leprae_Br4923          VCGHSFESVDHATDVGFMQEKWSMMRGQN-----------AYSVAYTAPA
TH_1275|M.thermoresistible__bu      RCARSFDDLDRATEISFERETWSSIKGRS-----------TFTAAYSAPG
MSMEG_0082|M.smegmatis_MC2_155      RCCRSFDDYEKATEISYERETWSSIKGRS-----------TFTAAYTAPG
Mflv_0756|M.gilvum_PYR-GCK          RPARSFDDFDGATEISFERETWSMVKGRS-----------TFTAAYHAPG
Mvan_0091|M.vanbaalenii_PYR-1       RPARSFDDFDRATEISFERETWSMVKGRS-----------TFTAAYHAPG
MAB_3760|M.abscessus_ATCC_1997      TILQAGQIHRISAEMLRQYAGAPMHEDWSGL---------TLIDSYNVAM
MUL_3078|M.ulcerans_Agy99           RPLAADELAEVDSTILAELAPTWSRPGWR---------------------
MAV_0159|M.avium_104                KVANATDLAELDRRLGWDAVSGTVQRWKAIRGEAGWMTTYAYPPQAITSR
                                        : :       :                                   

Mb3912c|M.bovis_AF2122/97           GPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPR---------
Rv3882c|M.tuberculosis_H37Rv        GPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPR---------
MMAR_5458|M.marinum_M               GPDLWWSARADHTITRVRIAPGMPPRSTVLLTTVGKPKTPR---------
MLBr_00042|M.leprae_Br4923          GPDAWWSARADHTITRVRVAPGKTPQATVVLTTLGKPKTPC---------
TH_1275|M.thermoresistible__bu      GPDVWWSARADHTITRLRVRPGAPPTSTVLLTTLANPTTPR---------
MSMEG_0082|M.smegmatis_MC2_155      GPDMWWSARADHTITRVRVRPGAAPSSAILLTTLANPTTPR---------
Mflv_0756|M.gilvum_PYR-GCK          GPDVWWSARADYTLTRVRIVPGAAPTATVLLTTLANPSTPR---------
Mvan_0091|M.vanbaalenii_PYR-1       GPDVWWSARADHTLTRMRIVPGSAPTTTVLLTTLANPSTPR---------
MAB_3760|M.abscessus_ATCC_1997      GIDPWYIT--DATLTGLWARPTLETSVTVRLRPAAKGRTSVGALVRWATD
MUL_3078|M.ulcerans_Agy99           -----HLKHFNGYATSFWVTPADINAETLDEVWLSDAPEVG---------
MAV_0159|M.avium_104                NLSQAWTLRADEVIQNVTVYPDGHCSATITVRTPTPAPTPP---------
                                              :     .   *      ::                     

Mb3912c|M.bovis_AF2122/97           ---------GFARLFGGQRPALQGQHLVANR-----------------HC
Rv3882c|M.tuberculosis_H37Rv        ---------GFARLFGGQRPALQGQHLVANR-----------------HC
MMAR_5458|M.marinum_M               ---------GFSRLFGSQRPALEGQTLVANH-----------------HC
MLBr_00042|M.leprae_Br4923          ---------GFYRLHGAQQPALLGRSFVAYQ-----------------HC
TH_1275|M.thermoresistible__bu      ---------GFSCLFGGQRAALEGLSPVTDK-----------------HH
MSMEG_0082|M.smegmatis_MC2_155      ---------GFSCLFGGQRAALQGIVPVSDK-----------------HY
Mflv_0756|M.gilvum_PYR-GCK          ---------GFSCLYGGQRAALLGESPVTDR-----------------HY
Mvan_0091|M.vanbaalenii_PYR-1       ---------GFSCLFGGQRAALLGENPVTDR-----------------HY
MAB_3760|M.abscessus_ATCC_1997      EQLPVRHSTGMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEMSNEELDGI
MUL_3078|M.ulcerans_Agy99           --------------------------------------------------
MAV_0159|M.avium_104                --------SVILRRLNGEQAAAAAANMCGPRPHLRG----LRRSRLPAEL
                                                                                      

Mb3912c|M.bovis_AF2122/97           QLPIGSAGVLVGETVNRCPVYMPFDD---VDIALNLGDAQTFTQFVVRAA
Rv3882c|M.tuberculosis_H37Rv        QLPIGSAGVLVGETVNRCPVYMPFDD---VDIALNLGDAQTFTQFVVRAA
MMAR_5458|M.marinum_M               QLPIGSAGVLIGETVNRRPVYMPFDD---VDATVNLGDAQTFTQFAVRSA
MLBr_00042|M.leprae_Br4923          QMPIGSAGVLVGETVNRCSVYMPFDD---VDVSVSLGDVQTFTQFVVRAA
TH_1275|M.thermoresistible__bu      ELPIGSAGVLVGETVDRYPVYMPFDD---VDVSINLGDARLFTQFVVRSA
MSMEG_0082|M.smegmatis_MC2_155      DLPIGSAGVLVGETADRYPVYMPFDN---VDVSINLGDARLFTQFVIRSA
Mflv_0756|M.gilvum_PYR-GCK          ELPIGSAGVLVGETADRYPVYMPFDD---TDVSINLGNARLFTQFVVRSA
Mvan_0091|M.vanbaalenii_PYR-1       ELPIGSAGVLVGETADRYPVYMPFDD---VDVSINLGNARLFTQFVVRSA
MAB_3760|M.abscessus_ATCC_1997      HLPTSGCGQLIGSDMSGRAIATRLSGQ-GVHTVVVRAELYVCQQVVLRAV
MUL_3078|M.ulcerans_Agy99           -ATVLTLRLVMRAGEPRLSAWVRYHS----------------DERLPKEL
MAV_0159|M.avium_104                ITEIGPSGVLIGKLPNGDRLLMPVTDAGELSRVFVAADDPIAKRIVIRTA
                                             ::              .                 .   :  

Mb3912c|M.bovis_AF2122/97           AAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGP----------
Rv3882c|M.tuberculosis_H37Rv        AAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGP----------
MMAR_5458|M.marinum_M               AAGGVVTVGPHFEQFAGLIGAHVGAEAKVVWPNATTYLGA----------
MLBr_00042|M.leprae_Br4923          AAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLDP----------
TH_1275|M.thermoresistible__bu      AAGGVVTLLPQFREFASLINARVGPEAKISWPNATTYLGP----------
MSMEG_0082|M.smegmatis_MC2_155      AAGAVVTLGPQFREFATMINGRVGRTPRIGWPNATTYLGP----------
Mflv_0756|M.gilvum_PYR-GCK          AAGANVTLQPQFGEFAGYVNAQIGPTAKVAWPHATTYLRP----------
Mvan_0091|M.vanbaalenii_PYR-1       AAGAAVTLQPQFEEFAGFVNARIGQVAKVAWPHATTYLRP----------
MAB_3760|M.abscessus_ATCC_1997      AIGALVVVYTDRPHMWDVMVTSIGDANRIQFASGPGFIDPRCTLAVVDGM
MUL_3078|M.ulcerans_Agy99           SVGLNRLTGRQLAAVRASLPVPSTRAQLVVSS------------------
MAV_0159|M.avium_104                GAGERVCVHTRDMSRWVSVRMPEISVVNSSRPAPRTTVSVVEYAPRRGEG
                                    . *               :            .                  

Mb3912c|M.bovis_AF2122/97           ---------------------------HPGIDRVILR------HNVIGTP
Rv3882c|M.tuberculosis_H37Rv        ---------------------------HPGIDRVILR------HNVIGTP
MMAR_5458|M.marinum_M               ---------------------------HPGIDRVILR------HNLVGTP
MLBr_00042|M.leprae_Br4923          ---------------------------YPGSERVILK------HDIIGTP
TH_1275|M.thermoresistible__bu      ---------------------------HPGIGRVILR------HNFIDTP
MSMEG_0082|M.smegmatis_MC2_155      ---------------------------HQGVGRVILR------PNFIDTP
Mflv_0756|M.gilvum_PYR-GCK          ---------------------------QPGVGRVVLR------DNFIATP
Mvan_0091|M.vanbaalenii_PYR-1       ---------------------------HPGVGRVMLR------DDFIATP
MAB_3760|M.abscessus_ATCC_1997      QPTALPSNCTALHIISSEYD------ALPARPDVIIDQPNGYGDHILLTA
MUL_3078|M.ulcerans_Agy99           --------------------------------RELLD-------------
MAV_0159|M.avium_104                VEAAISPTPRPATVITVAPAGTTLSEAQRHGFEVIIEQVSPAVVNVSAAG
                                                                      ::              

Mb3912c|M.bovis_AF2122/97           RHRQLPIRRVSPPEESRYQMALPK-----
Rv3882c|M.tuberculosis_H37Rv        RHRQLPIRRVSPPEESRYQMALPK-----
MMAR_5458|M.marinum_M               RHRKLPIRRVSPPEESRFQMALPK-----
MLBr_00042|M.leprae_Br4923          RHRKLPIRRISPPEEGHYQMVLPKSSYEL
TH_1275|M.thermoresistible__bu      RHRQLPIRLINPREESRYQMALEG-----
MSMEG_0082|M.smegmatis_MC2_155      RHRQLPIQLINPREESRYQMALEQ-----
Mflv_0756|M.gilvum_PYR-GCK          RHKELPIRLINPREESRYQMALEP-----
Mvan_0091|M.vanbaalenii_PYR-1       RHKQLPIRLINPREESRYQMVLEP-----
MAB_3760|M.abscessus_ATCC_1997      GGETIQVRLVTVSDELAYLGRPIQAFAQ-
MUL_3078|M.ulcerans_Agy99           -HDELELPVGQTQEHATSATTGQ------
MAV_0159|M.avium_104                KNWLVEMDMFRAEHRYVSLEPVSMSVGM-
                                        : :      ..