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MRPNLTGFSRGSNRRVVGVWVVFVLALASWLLGGYIAAAVAVLVGVALVFVRWWGQPAWSWAVLWRRGRR PIDWSAPITVANNRSGGGVRVQDGVAVVAVQLLGRAHRATLVTGSVTVETENVLDVVELAPMLHQALGLQ LDSISVVTVGSRHGNVGDYPRVYDSEIGTPPYAGRRETWLIMRLAVIDNAQALRWRTTVGAAAISVAQRI AGLLRCQGLRAKVANATDLAELDRRLGWDAVSGTVQRWKAIRGEAGWMTTYAYPPQAITSRNLSQAWTLR ADEVIQNVTVYPDGHCSATITVRTPTPAPTPPSVILRRLNGEQAAAAAANMCGPRPHLRGLRRSRLPAEL ITEIGPSGVLIGKLPNGDRLLMPVTDAGELSRVFVAADDPIAKRIVIRTAGAGERVCVHTRDMSRWVSVR MPEISVVNSSRPAPRTTVSVVEYAPRRGEGVEAAISPTPRPATVITVAPAGTTLSEAQRHGFEVIIEQVS PAVVNVSAAGKNWLVEMDMFRAEHRYVSLEPVSMSVGM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0159 | - | - | 100% (528) | hypothetical protein MAV_0159 |
| M. avium 104 | MAV_2917 | - | 2e-09 | 25.71% (350) | hypothetical protein MAV_2917 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3915c | - | 0.0 | 79.14% (532) | hypothetical protein Mb3915c |
| M. gilvum PYR-GCK | Mflv_0756 | - | 1e-14 | 27.01% (385) | hypothetical protein Mflv_0756 |
| M. tuberculosis H37Rv | Rv3885c | - | 0.0 | 79.32% (532) | hypothetical protein Rv3885c |
| M. leprae Br4923 | MLBr_00042 | - | 5e-16 | 26.11% (383) | hypothetical protein MLBr_00042 |
| M. abscessus ATCC 19977 | MAB_3760 | - | 9e-13 | 23.40% (453) | hypothetical protein MAB_3760 |
| M. marinum M | MMAR_2679 | - | 5e-14 | 25.41% (362) | hypothetical protein MMAR_2679 |
| M. smegmatis MC2 155 | MSMEG_0082 | - | 1e-10 | 23.84% (365) | hypothetical protein MSMEG_0082 |
| M. thermoresistible (build 8) | TH_1275 | - | 1e-14 | 25.87% (429) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3078 | - | 3e-14 | 25.21% (361) | hypothetical protein MUL_3078 |
| M. vanbaalenii PYR-1 | Mvan_0091 | - | 4e-13 | 24.26% (408) | hypothetical protein Mvan_0091 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0082|M.smegmatis_MC2_155 ----MNFLR-QFGFRFTTGHGIWAATLIPACIAICMHFDL----------
TH_1275|M.thermoresistible__bu ----MKSLRNLFGMRFSTGHGIWAAVLIPAVVVLFERLEM----------
Mflv_0756|M.gilvum_PYR-GCK ----MSRFLSIFGVRFTTGHALWAAVLVPACILIFAQLNL----------
Mvan_0091|M.vanbaalenii_PYR-1 ----MSRFASIFGLRFTTGHALWAAALIPACILVFARLEL----------
MLBr_00042|M.leprae_Br4923 -------MRNPVWLRFSMGRALLVTALVPPCIILFFHTQY----------
MMAR_2679|M.marinum_M -------MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRI
MUL_3078|M.ulcerans_Agy99 -------MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRI
Mb3915c|M.bovis_AF2122/97 ------------MTSKLTGFSPRSARRVAGVWTVFVLASAG---------
Rv3885c|M.tuberculosis_H37Rv ------------MTSKLTGFSPRSARRVAGVWTVFVLASAG---------
MAV_0159|M.avium_104 ------------MRPNLTGFSRGSNRRVVGVWVVFVLALAS---------
MAB_3760|M.abscessus_ATCC_1997 MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISLLFGWP---------
: :
MSMEG_0082|M.smegmatis_MC2_155 -LWLGITLGALIALFSVLTIRGLRIT-GWVRAIFSWRRRHRSTPDIASEP
TH_1275|M.thermoresistible__bu -LWLGVVVAVFIAPASVLTIRGRRLT-GWVAAVFSWRRRHRVPPARPSEP
Mflv_0756|M.gilvum_PYR-GCK -LWLGITLAVLIALCALVTIRGRRIT-GWIAALFAWRRRHRQPPPAPSEP
Mvan_0091|M.vanbaalenii_PYR-1 -LWLGITLGVLIGLASVVTIRGRRLT-GWVAALFAWRRRHRQPPPTPSEP
MLBr_00042|M.leprae_Br4923 -WWAGIALVVLVVILTLVEFSGRWLS-GWLMALYSFFRRSSKPLDTPSEP
MMAR_2679|M.marinum_M AWWVGVGIAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTP
MUL_3078|M.ulcerans_Agy99 AWWVGVGIAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTP
Mb3915c|M.bovis_AF2122/97 -WALGGQLGAVMAVVVGVALVFVQWW-GQPAWSWAVLGLRGRRPVKWNDP
Rv3885c|M.tuberculosis_H37Rv -WALGGQLGAVMAVVVGVALVFVQWW-GQPAWSWAVLGLRGRRPVKWNDP
MAV_0159|M.avium_104 -WLLGGYIAAAVAVLVGVALVFVRWW-GQPAWSWAVLWRRGRRPIDWSAP
MAB_3760|M.abscessus_ATCC_1997 -WWAALLIAIVSLALVLGRWGGQTVRHWAVTGFKYLTGRTYRSSGSIADT
. : .
MSMEG_0082|M.smegmatis_MC2_155 AVGSTVMPG-DHVAVRWQGDYLIAVIELVPRPFTPTVIVNGSAMTDDVVN
TH_1275|M.thermoresistible__bu AVGATVAPG-DHVAVRWQGDHLVSAIELVPRPFTPTVLVNGKAFTDDLLD
Mflv_0756|M.gilvum_PYR-GCK AVGATVVPG-DHVALRWQHGYLVSAIELIPRPFTPTVIVNGEAFTDDVID
Mvan_0091|M.vanbaalenii_PYR-1 AVGATVIPG-DHVALRWQDDYLVSVIELVPRPFTPTVIVNGEAFTDDVVE
MLBr_00042|M.leprae_Br4923 VIGATVKPA-DQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLE
MMAR_2679|M.marinum_M AVDHQRRFGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVP
MUL_3078|M.ulcerans_Agy99 AVDHQRRFGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVP
Mb3915c|M.bovis_AF2122/97 ITLANNRSG---GGVRVQDGVAVVAVQLLGRAHRATTVTGSVTVESDNVI
Rv3885c|M.tuberculosis_H37Rv ITLANNRSG---GGVRVQDGVAVVAVQLLGRAHRATTVTGSVTVESDNVI
MAV_0159|M.avium_104 ITVANNRSG---GGVRVQDGVAVVAVQLLGRAHRATLVTGSVTVETENVL
MAB_3760|M.abscessus_ATCC_1997 PSGQDSWTG-----TRWENGKLITVLEISATQRHPSVITPDHCATDSLVP
. * . . : .: : .: :
MSMEG_0082|M.smegmatis_MC2_155 TKLVERLLEAHCPDLE-ADVVSAGYRVGKTAPASLIALYEQ------VVG
TH_1275|M.thermoresistible__bu TRLVEQLLTAHCPDLE-ADIVSAGYRVGKTAPASLLALYEQ------VLG
Mflv_0756|M.gilvum_PYR-GCK SRQLEKLLAAYCPDLE-ADIVSAGYRVGRTAPAALVGLYEQ------VVG
Mvan_0091|M.vanbaalenii_PYR-1 TRLVEDLLTAYCPDLE-ADIVSAGYRVGKTAPAALVALYEQ------VVG
MLBr_00042|M.leprae_Br4923 TQLLEHLLSVHCPDLE-AVVVSAGYRVGHVASLDVVNLYQQ------VIG
MMAR_2679|M.marinum_M VATVAENLRQFDVQLDGVDIVTVEVRGGAEAARASASLDEWGPEEWGMVG
MUL_3078|M.ulcerans_Agy99 VATVAENLRQFDVQLDGVDIMTVEVRGGAEAARASASLDEWGPEEWGMVG
Mb3915c|M.bovis_AF2122/97 DVVELAPLPRHPLDLELDSISVVTFGSRTGTVGDYPRVYDA------EIG
Rv3885c|M.tuberculosis_H37Rv DVVELAPLLRHPLDLELDSISVVTFGSRTGTVGDYPRVYDA------EIG
MAV_0159|M.avium_104 DVVELAPMLHQALGLQLDSISVVTVGSRHGNVGDYPRVYDS------EIG
MAB_3760|M.abscessus_ATCC_1997 LRVLRECMHQNDIELESIDVISNGQRTAQGTVLRGG--YDR------LVG
: *: : : :*
MSMEG_0082|M.smegmatis_MC2_155 PYPAPANRRTWIVLRADPEKTQRSAHRRDSGVSGLARYLVASATRIADQL
TH_1275|M.thermoresistible__bu PYPAPANRRTWIVLRADPERTQKSARRRDVGVAGLSRYLVASTTRIADQL
Mflv_0756|M.gilvum_PYR-GCK PYPAPARRRTWIVLRADPDKTRKSALRRDVGVSGLAQYVVSSTTRIADHL
Mvan_0091|M.vanbaalenii_PYR-1 PYPAPASRRTWIVLRADPDKTRKSALRRNEGVAGLAQYLVSSTTRIADHL
MLBr_00042|M.leprae_Br4923 ADPAPAHRRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQL
MMAR_2679|M.marinum_M ESPAANRRRTWLILRMNPQRNVAAIASRDS----LASTLVTATERLAQVL
MUL_3078|M.ulcerans_Agy99 ESPAANRRRTWLILRMNPQRNVAAIASRDS----LASTLVTATERLAQVL
Mb3915c|M.bovis_AF2122/97 TPPYAGRRETWLIMRLPVIGNTQALRWRTS----VGAAAISVAQRVASSL
Rv3885c|M.tuberculosis_H37Rv TPPYAGRRETWLIMRLPVIGNTQALRWRTS----VGAAAISVAQRVASSL
MAV_0159|M.avium_104 TPPYAGRRETWLIMRLAVIDNAQALRWRTT----VGAAAISVAQRIAGLL
MAB_3760|M.abscessus_ATCC_1997 PLPAVAIRTVWVVLRFDPGANVDAVFRRGGGRRGAERCAVIATARVRRAL
* * .*:::* . : * : : *: *
MSMEG_0082|M.smegmatis_MC2_155 ASNGVDARCCRSFDDYEKAT------EISYERETWSSIKGRSTFTAAYTA
TH_1275|M.thermoresistible__bu ASHGVDARCARSFDDLDRAT------EISFERETWSSIKGRSTFTAAYSA
Mflv_0756|M.gilvum_PYR-GCK ASNGIDARPARSFDDFDGAT------EISFERETWSMVKGRSTFTAAYHA
Mvan_0091|M.vanbaalenii_PYR-1 ASKGVDARPARSFDDFDRAT------EISFERETWSMVKGRSTFTAAYHA
MLBr_00042|M.leprae_Br4923 ASHGVDAVCGHSFESVDHAT------DVGFMQEKWSMMRGQNAYSVAYTA
MMAR_2679|M.marinum_M DGQ---SCAARPLAADELAE------VDSAILAELEPTWSRPGWRHLKHF
MUL_3078|M.ulcerans_Agy99 DGQ---SCAARPLAADELAE------VDSTILAELAPTWSRPGWRHLKHF
Mb3915c|M.bovis_AF2122/97 RCQGLRAKLATATDLAELDRRLG-SDAVAGSAQRWKAIRGEAGWMTTYAY
Rv3885c|M.tuberculosis_H37Rv RCQGLRAKLATATDLAELDRRLG-SDAVAGSAQRWKAIRGEAGWMTTYAY
MAV_0159|M.avium_104 RCQGLRAKVANATDLAELDRRLG-WDAVSGTVQRWKAIRGEAGWMTTYAY
MAB_3760|M.abscessus_ATCC_1997 AAAHCASTILQAGQIHRISAEMLRQYAGAPMHEDWSGLTLIDSYNVAMGI
: . . :
MSMEG_0082|M.smegmatis_MC2_155 PGGPD------MWWSARADH--------------TITRVRVRPGAAPSSA
TH_1275|M.thermoresistible__bu PGGPD------VWWSARADH--------------TITRLRVRPGAPPTST
Mflv_0756|M.gilvum_PYR-GCK PGGPD------VWWSARADY--------------TLTRVRIVPGAAPTAT
Mvan_0091|M.vanbaalenii_PYR-1 PGGPD------VWWSARADH--------------TLTRMRIVPGSAPTTT
MLBr_00042|M.leprae_Br4923 PAGPD------AWWSARADH--------------TITRVRVAPGKTPQAT
MMAR_2679|M.marinum_M NGYAT------SFWVTPADINAE-----------TLDEVWLSDAPEVGAT
MUL_3078|M.ulcerans_Agy99 NGYAT------SFWVTPADINAE-----------TLDEVWLSDAPEVGAT
Mb3915c|M.bovis_AF2122/97 PAEAISSRVLSQAWTLRADEVIQNVTVYPDATCTATITVRTPTPAPTPPS
Rv3885c|M.tuberculosis_H37Rv PAEAISSRVLSQAWTLRADEVIQNVTVYPDATCTATITVRTPTPAPTPPS
MAV_0159|M.avium_104 PPQAITSRNLSQAWTLRADEVIQNVTVYPDGHCSATITVRTPTPAPTPPS
MAB_3760|M.abscessus_ATCC_1997 DPWYITDATLTGLWARPTLETS------------VTVRLRPAAKGRTSVG
* : . :
MSMEG_0082|M.smegmatis_MC2_155 ILLTTLANPTTPR----GFSCLFGGQRAALQGIVPV--------------
TH_1275|M.thermoresistible__bu VLLTTLANPTTPR----GFSCLFGGQRAALEGLSPV--------------
Mflv_0756|M.gilvum_PYR-GCK VLLTTLANPSTPR----GFSCLYGGQRAALLGESPV--------------
Mvan_0091|M.vanbaalenii_PYR-1 VLLTTLANPSTPR----GFSCLFGGQRAALLGENPV--------------
MLBr_00042|M.leprae_Br4923 VVLTTLGKPKTPC----GFYRLHGAQQPALLGRSFV--------------
MMAR_2679|M.marinum_M VLTLRLVMRAGEP----RLSAWVRYHSDERLP------------------
MUL_3078|M.ulcerans_Agy99 VLTLRLVMRAGEP----RLSAWVRYHSDERLP------------------
Mb3915c|M.bovis_AF2122/97 VILRRLNGEQAAA----AAANMCGPRPHLRGQRRCP--------------
Rv3885c|M.tuberculosis_H37Rv VILRRLNGEQAAA----AAANMCGPRPHLRGQRRCP--------------
MAV_0159|M.avium_104 VILRRLNGEQAAA----AAANMCGPRPHLRGLRRSR--------------
MAB_3760|M.abscessus_ATCC_1997 ALVRWATDEQLPVRHSTGMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEM
: :
MSMEG_0082|M.smegmatis_MC2_155 ---SDKHYDLPIGSAGVLVGETADRYPVYMPFDNVDVS---INLGDARLF
TH_1275|M.thermoresistible__bu ---TDKHHELPIGSAGVLVGETVDRYPVYMPFDDVDVS---INLGDARLF
Mflv_0756|M.gilvum_PYR-GCK ---TDRHYELPIGSAGVLVGETADRYPVYMPFDDTDVS---INLGNARLF
Mvan_0091|M.vanbaalenii_PYR-1 ---TDRHYELPIGSAGVLVGETADRYPVYMPFDDVDVS---INLGNARLF
MLBr_00042|M.leprae_Br4923 ---AYQHCQMPIGSAGVLVGETVNRCSVYMPFDDVDVS---VSLGDVQTF
MMAR_2679|M.marinum_M -------KELSVG-LNRLTGRQLAAVRASLPVPSTRAQ---LVVSSRELL
MUL_3078|M.ulcerans_Agy99 -------KELSVG-LNRLTGRQLAAVRASLPVPSTRAQ---LVVSSRELL
Mb3915c|M.bovis_AF2122/97 ---LPAQLVTEIGPSGVLIGKLSNGDRLMIPVTDAGELSRVFVAADDTIA
Rv3885c|M.tuberculosis_H37Rv ---LPAQLVTEIGPSGVLIGKLSNGDRLMIPVTDAGELSRVFVAADDTIA
MAV_0159|M.avium_104 ---LPAELITEIGPSGVLIGKLPNGDRLLMPVTDAGELSRVFVAADDPIA
MAB_3760|M.abscessus_ATCC_1997 SNEELDGIHLPTSGCGQLIGSDMSGRAIATRLSGQGVHT-VVVRAELYVC
. . * * . . . ..
MSMEG_0082|M.smegmatis_MC2_155 TQFVIRSAAAGAVVTLGPQFREFATMINGRVGRTPRIGWPNATTYLGPHQ
TH_1275|M.thermoresistible__bu TQFVVRSAAAGGVVTLLPQFREFASLINARVGPEAKISWPNATTYLGPHP
Mflv_0756|M.gilvum_PYR-GCK TQFVVRSAAAGANVTLQPQFGEFAGYVNAQIGPTAKVAWPHATTYLRPQP
Mvan_0091|M.vanbaalenii_PYR-1 TQFVVRSAAAGAAVTLQPQFEEFAGFVNARIGQVAKVAWPHATTYLRPHP
MLBr_00042|M.leprae_Br4923 TQFVVRAAAAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLDPYP
MMAR_2679|M.marinum_M DHDELELPVG----------QTQEHATSATTGQ-----------------
MUL_3078|M.ulcerans_Agy99 DHDELELPVG----------QTQEHATSATTGQ-----------------
Mb3915c|M.bovis_AF2122/97 KRIVIRVVGAGERVCVHTRDQERWASVRMPQLSIVGTPRPAPRTTVGVVE
Rv3885c|M.tuberculosis_H37Rv KRIVIRVVGAGERVCVHTRDQERWASVRMPQLSIVGTPRPAPRTTVGVVE
MAV_0159|M.avium_104 KRIVIRTAGAGERVCVHTRDMSRWVSVRMPEISVVNSSRPAPRTTVSVVE
MAB_3760|M.abscessus_ATCC_1997 QQVVLRAVAIGALVVVYTDRPHMWDVMVTSIGDANRIQFASGPGFIDPRC
: :.
MSMEG_0082|M.smegmatis_MC2_155 ----------------GVGRVILRPNFIDTPRHRQLPIQLINPREESRYQ
TH_1275|M.thermoresistible__bu ----------------GIGRVILRHNFIDTPRHRQLPIRLINPREESRYQ
Mflv_0756|M.gilvum_PYR-GCK ----------------GVGRVVLRDNFIATPRHKELPIRLINPREESRYQ
Mvan_0091|M.vanbaalenii_PYR-1 ----------------GVGRVMLRDDFIATPRHKQLPIRLINPREESRYQ
MLBr_00042|M.leprae_Br4923 ----------------GSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQ
MMAR_2679|M.marinum_M --------------------------------------------------
MUL_3078|M.ulcerans_Agy99 --------------------------------------------------
Mb3915c|M.bovis_AF2122/97 YVRRRKNGDDGKSEGSGVDVAISPTPRPASVITIARPGTSLSESDRHGFE
Rv3885c|M.tuberculosis_H37Rv YVRRRKNGDDGKSEGSGVDVAISPTPRPASVITIARPGTSLSESDRHGFE
MAV_0159|M.avium_104 YAPRR---------GEGVEAAISPTPRPATVITVAPAGTTLSEAQRHGFE
MAB_3760|M.abscessus_ATCC_1997 TLAVVDGMQPTALPSNCTALHIISSEYDALPARPDVIIDQPNGYGDHILL
MSMEG_0082|M.smegmatis_MC2_155 MALEQ----------------------------------------
TH_1275|M.thermoresistible__bu MALEG----------------------------------------
Mflv_0756|M.gilvum_PYR-GCK MALEP----------------------------------------
Mvan_0091|M.vanbaalenii_PYR-1 MVLEP----------------------------------------
MLBr_00042|M.leprae_Br4923 MVLPKSSYEL-----------------------------------
MMAR_2679|M.marinum_M ---------------------------------------------
MUL_3078|M.ulcerans_Agy99 ---------------------------------------------
Mb3915c|M.bovis_AF2122/97 VTIEQIDRATVKVGAAGQNWLVEMEMFRAENRYVSLEPVTMSIGR
Rv3885c|M.tuberculosis_H37Rv VTIEQIDRATVKVGAAGQNWLVEMEMFRAENRYVSLEPVTMSIGR
MAV_0159|M.avium_104 VIIEQVSPAVVNVSAAGKNWLVEMDMFRAEHRYVSLEPVSMSVGM
MAB_3760|M.abscessus_ATCC_1997 TAGGETIQVRLVTVSDELAYLGRPIQAFAQ---------------