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M. leprae Br4923 MLBr_01537 (-)

annotation: putative secreted protein
coordinates: 1853484 - 1854689
length: 401

KAQRRLGLALSWSRVTTVFVVAIVVLVLASHVPELWQAGHHVAWCVGVGITVVVMVLVLVSYHGITLMSG
LATWVWDCFADPRAALAAGCTPAIDHQRRFGRDVVGVREYKGRLVTVIAVDDGEDDPVGRHRHRTTPAGL
PVQAVADGLRQFDIRLDSIDIVSVKIRRGGNAAKFSALDNWGSEEWGLVCACPPTYQRCTWLVLRMNPQH
NVVAVAARDSLASTLVAATERLAQDLDGQNCAARPLAAGELAEVDSAVLADLEPTWSYPGWRHIKYVNGF
ATSFWVTPSDIDSETLNELWLSDLPDIKATVITIRLASRSCQTRLSAWVRHHSETRLSKEACRGLNQLTG
RQLAAVRASLPAPATRPVLVVPSRELSDHDELVLPVGQGREGSASLFAGQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01537--100% (401)putative secreted protein
M. leprae Br4923MLBr_00042-2e-0524.03% (233) hypothetical protein MLBr_00042

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1825-1e-15267.98% (406) hypothetical protein Mb1825
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1797-1e-15267.98% (406) hypothetical protein Rv1797
M. abscessus ATCC 19977MAB_3760-1e-1824.94% (385) hypothetical protein MAB_3760
M. marinum MMMAR_2679-1e-15766.50% (403) hypothetical protein MMAR_2679
M. avium 104MAV_2917-1e-14464.94% (405) hypothetical protein MAV_2917
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_3078-1e-15665.76% (403) hypothetical protein MUL_3078
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1825|M.bovis_AF2122/97            MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVG
Rv1797|M.tuberculosis_H37Rv         MKAQRSFGLALSWPRVTAVFLVDVLILAVASHCPDSWQADHHVAWWVGVG
MMAR_2679|M.marinum_M               MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVG
MUL_3078|M.ulcerans_Agy99           MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVG
MLBr_01537|M.leprae_Br4923          MKAQRRLGLALSWSRVTTVFVVAIVVLVLASHVPELWQAGHHVAWCVGVG
MAV_2917|M.avium_104                MKAQRRLGLSLTWPRLTTVFLVDIVIMVVASHCPESWQGTYRIAFWVGVG
MAB_3760|M.abscessus_ATCC_1997      MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISLLFG---WPWWAALL
                                    *.:.      :  . :.  :::   :: :*:   .   .    .: ..: 

Mb1825|M.bovis_AF2122/97            VAAVVTLLSVVSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRR
Rv1797|M.tuberculosis_H37Rv         VAAVVTLLSVVSYHGITVISGLATWVRDWSADPGTTLGAGCTPAIDHQRR
MMAR_2679|M.marinum_M               IAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRR
MUL_3078|M.ulcerans_Agy99           IAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRR
MLBr_01537|M.leprae_Br4923          ITVVVMVLVLVSYHGITLMSGLATWVWDCFADPRAALAAGCTPAIDHQRR
MAV_2917|M.avium_104                LAVLVTLLSLVTYHGITVASGLATWLWDWSADPGSALAAGCTPALDHQRR
MAB_3760|M.abscessus_ATCC_1997      IAIVSLALVLGRWGGQTVRHWAVTGFKYLTGRTYRSSGSIADTPSGQDSW
                                    :: :   * :  : * *:    .: .    . .  : .: . .. .::  

Mb1825|M.bovis_AF2122/97            FGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADG
Rv1797|M.tuberculosis_H37Rv         FGRDTVGVREYNGRLVSVIEVTCGESGPSGRHWHRKSPVPMLPVVAVADG
MMAR_2679|M.marinum_M               FGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAEN
MUL_3078|M.ulcerans_Agy99           FGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAEN
MLBr_01537|M.leprae_Br4923          FGRDVVGVREYKGRLVTVIAVDDGEDDPVGRHRHRTTPAG-LPVQAVADG
MAV_2917|M.avium_104                FGRDKVGVREYKGQLVSVIAVNGGEDETGSRHRHR-AASPTLLVAAVASG
MAB_3760|M.abscessus_ATCC_1997      TG-----TRWENGKLITVLEISATQRHPSVITPDHCATDSLVPLRVLREC
                                     *     .*  :*:*::*: :   :  .     .: :    : : .: . 

Mb1825|M.bovis_AF2122/97            LRQFDIHLDGIDIVSVLVRGGVDAAKASAS--LQEWEPQGWKSEERAGDR
Rv1797|M.tuberculosis_H37Rv         LRQFDIHLDGIDIVSVLVRGGVDAAKASAS--LQEWEPQGWKSEERAGDR
MMAR_2679|M.marinum_M               LRQFDVQLDGVDIVTVEVRGGAEAARASAS--LDEWGPEEWG---MVGES
MUL_3078|M.ulcerans_Agy99           LRQFDVQLDGVDIMTVEVRGGAEAARASAS--LDEWGPEEWG---MVGES
MLBr_01537|M.leprae_Br4923          LRQFDIRLDSIDIVSVKIRRGGNAAKFSA---LDNWGSEEWG---LVCAC
MAV_2917|M.avium_104                LRQFDIHLDDIDIVSVKVRRGGPDARSAELSKLDDFGPEEWD---VVGDE
MAB_3760|M.abscessus_ATCC_1997      MHQNDIELESIDVISNGQRTAQGTVLRGGYD-------------RLVGPL
                                    ::* *:.*:.:*:::   * .   .  .                  .   

Mb1825|M.bovis_AF2122/97            TVADRRRTWLVLRMNPQRNVAAVACRDS----LASTLVAATERLVQDLDG
Rv1797|M.tuberculosis_H37Rv         TVADRRRTWLVLRMNPQRNVAAVACRDS----LASTLVAATERLVQDLDG
MMAR_2679|M.marinum_M               PAANRRRTWLILRMNPQRNVAAIASRDS----LASTLVTATERLAQVLDG
MUL_3078|M.ulcerans_Agy99           PAANRRRTWLILRMNPQRNVAAIASRDS----LASTLVTATERLAQVLDG
MLBr_01537|M.leprae_Br4923          PPTYQRCTWLVLRMNPQHNVVAVAARDS----LASTLVAATERLAQDLDG
MAV_2917|M.avium_104                PTSYIRRTWLVLRMNPQRNVAAVAARDS----LASTLVAATERLAQDLDG
MAB_3760|M.abscessus_ATCC_1997      PAVAIRTVWVVLRFDPGANVDAVFRRGGGRRGAERCAVIATARVRRALAA
                                    .    * .*::**::*  ** *:  *..         * ** *: : * .

Mb1825|M.bovis_AF2122/97            QSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTP
Rv1797|M.tuberculosis_H37Rv         QSCAARPVTADELTEVDSAVLADLEPTWSRPGWRHLKHFNGYATSFWVTP
MMAR_2679|M.marinum_M               QSCAARPLAADELAEVDSAILAELEPTWSRPGWRHLKHFNGYATSFWVTP
MUL_3078|M.ulcerans_Agy99           QSCAARPLAADELAEVDSTILAELAPTWSRPGWRHLKHFNGYATSFWVTP
MLBr_01537|M.leprae_Br4923          QNCAARPLAAGELAEVDSAVLADLEPTWSYPGWRHIKYVNGFATSFWVTP
MAV_2917|M.avium_104                LTCAARPLTAEEIAEVDRAVLADLEPTWSRPGWRRLKHFNGFVTSLWLSP
MAB_3760|M.abscessus_ATCC_1997      AHCASTILQAGQIHRISAEMLRQYAGAPMHEDWSGLTLIDSYNVAMGIDP
                                      **:  : * :: .:.  :* :   :    .*  :. .:.: .:: : *

Mb1825|M.bovis_AF2122/97            SDITSETLDELCLPDSPEVGTTVVTVRLTTRVGSPALSAWVRYHSDTRLP
Rv1797|M.tuberculosis_H37Rv         SDITSETLDELCLPDSPEVGTTVVTVRLTTRVGSPALSAWVRYHSDTRLP
MMAR_2679|M.marinum_M               ADINAETLDEVWLSDAPEVGATVLTLRLVMRAGEPRLSAWVRYHSDERLP
MUL_3078|M.ulcerans_Agy99           ADINAETLDEVWLSDAPEVGATVLTLRLVMRAGEPRLSAWVRYHSDERLP
MLBr_01537|M.leprae_Br4923          SDIDSETLNELWLSDLPDIKATVITIRLASRSCQTRLSAWVRHHSETRLS
MAV_2917|M.avium_104                SDITTDKLEELWDDDT---FATVLTIRLTARAGRPHVSAWVRYHTEKRLR
MAB_3760|M.abscessus_ATCC_1997      WYITDATLTGLWARPTLETSVTVRLR--PAAKGRTSVGALVRWATDEQLP
                                      *   .*  :         .**           . :.* **  :: :* 

Mb1825|M.bovis_AF2122/97            KEVAAGLNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLR--DHDELVLPV
Rv1797|M.tuberculosis_H37Rv         KEVAAGLNRLTGRQLAAVRASLPAPTHRPLLVIPSRNLR--DHDELVLPV
MMAR_2679|M.marinum_M               KELSVGLNRLTGRQLAAVRASLPVPSTRAQLVVSSRELL--DHDELELPV
MUL_3078|M.ulcerans_Agy99           KELSVGLNRLTGRQLAAVRASLPVPSTRAQLVVSSRELL--DHDELELPV
MLBr_01537|M.leprae_Br4923          KEACRGLNQLTGRQLAAVRASLPAPATRPVLVVPSRELS--DHDELVLPV
MAV_2917|M.avium_104                RNISSGLNRLTGRQLAAVRASLPVPTARPLLEVPSRPLRA-DDDELSLSL
MAB_3760|M.abscessus_ATCC_1997      VRHSTGMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEMSNEELDGIHLPT
                                     . . *:. *.* *  *. *.**. :        *  :   : * : *. 

Mb1825|M.bovis_AF2122/97            GQELEHATSSFVGQ------------------------------------
Rv1797|M.tuberculosis_H37Rv         GQELEHATSSFVGQ------------------------------------
MMAR_2679|M.marinum_M               GQTQEHATSATTGQ------------------------------------
MUL_3078|M.ulcerans_Agy99           GQTQEHATSATTGQ------------------------------------
MLBr_01537|M.leprae_Br4923          GQGREGSASLFAGQ------------------------------------
MAV_2917|M.avium_104                AAPRESAAGVPAAQ------------------------------------
MAB_3760|M.abscessus_ATCC_1997      SGCGQLIGSDMSGRAIATRLSGQGVHTVVVRAELYVCQQVVLRAVAIGAL
                                    .   :   .   .:                                    

Mb1825|M.bovis_AF2122/97            --------------------------------------------------
Rv1797|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2679|M.marinum_M               --------------------------------------------------
MUL_3078|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01537|M.leprae_Br4923          --------------------------------------------------
MAV_2917|M.avium_104                --------------------------------------------------
MAB_3760|M.abscessus_ATCC_1997      VVVYTDRPHMWDVMVTSIGDANRIQFASGPGFIDPRCTLAVVDGMQPTAL
                                                                                      

Mb1825|M.bovis_AF2122/97            --------------------------------------------------
Rv1797|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2679|M.marinum_M               --------------------------------------------------
MUL_3078|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01537|M.leprae_Br4923          --------------------------------------------------
MAV_2917|M.avium_104                --------------------------------------------------
MAB_3760|M.abscessus_ATCC_1997      PSNCTALHIISSEYDALPARPDVIIDQPNGYGDHILLTAGGETIQVRLVT
                                                                                      

Mb1825|M.bovis_AF2122/97            -----------------
Rv1797|M.tuberculosis_H37Rv         -----------------
MMAR_2679|M.marinum_M               -----------------
MUL_3078|M.ulcerans_Agy99           -----------------
MLBr_01537|M.leprae_Br4923          -----------------
MAV_2917|M.avium_104                -----------------
MAB_3760|M.abscessus_ATCC_1997      VSDELAYLGRPIQAFAQ