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MRNPLGLRFSTGHALLASALAPPCIIAFLETRYWWAGIALASLGVIVATVTFYGRRITGWVAAVYAWLRR RRRPPDSSSEPVVGATVKPGDHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEELLSV HCPDLEADIVSAGYRVGNTAAPDVVSLYQQVIGTDPAPANRRTWIVLRADPERTRKSAQRRDEGVAGLAR YLVASATRIADRLASHGVDAVCGRSFDDYDHATDIGFVREKWSMIKGRDAYTAAYAAPGGPDVWWSARAD HTITRVRVAPGMAPQSTVLLTTADKPKTPRGFARLFGGQRPALQGQHLVANRHCQLPIGSAGVLVGETVN RCPVYMPFDDVDIALNLGDAQTFTQFVVRAAAAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLG PHPGIDRVILRHNVIGTPRHRQLPIRRVSPPEESRYQMALPK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3912c | - | - | 100% (462) | hypothetical protein Mb3912c |
M. bovis AF2122 / 97 | Mb3915c | - | 1e-18 | 27.13% (387) | hypothetical protein Mb3915c |
M. bovis AF2122 / 97 | Mb1825 | - | 8e-08 | 25.55% (274) | hypothetical protein Mb1825 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0756 | - | 1e-180 | 66.37% (455) | hypothetical protein Mflv_0756 |
M. tuberculosis H37Rv | Rv3882c | - | 0.0 | 100.00% (462) | hypothetical protein Rv3882c |
M. leprae Br4923 | MLBr_00042 | - | 0.0 | 72.29% (462) | hypothetical protein MLBr_00042 |
M. abscessus ATCC 19977 | MAB_3760 | - | 9e-16 | 22.50% (440) | hypothetical protein MAB_3760 |
M. marinum M | MMAR_5458 | - | 0.0 | 81.51% (465) | hypothetical protein MMAR_5458 |
M. avium 104 | MAV_0159 | - | 5e-18 | 26.38% (398) | hypothetical protein MAV_0159 |
M. smegmatis MC2 155 | MSMEG_0082 | - | 0.0 | 66.81% (455) | hypothetical protein MSMEG_0082 |
M. thermoresistible (build 8) | TH_1275 | - | 0.0 | 69.57% (460) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_3078 | - | 8e-09 | 29.05% (210) | hypothetical protein MUL_3078 |
M. vanbaalenii PYR-1 | Mvan_0091 | - | 0.0 | 68.35% (455) | hypothetical protein Mvan_0091 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3912c|M.bovis_AF2122/97 ----MRNPLG---LRFSTGHALLASALAPPCIIAFLETRY----WWAGIA Rv3882c|M.tuberculosis_H37Rv ----MRNPLG---LRFSTGHALLASALAPPCIIAFLETRY----WWAGIA MMAR_5458|M.marinum_M ----MRNPFSSIRFRVSTGHTLVVAVLAPPCIMMFLHMRY----WWVGIA MLBr_00042|M.leprae_Br4923 ----MRNPVW---LRFSMGRALLVTALVPPCIILFFHTQY----WWAGIA MSMEG_0082|M.smegmatis_MC2_155 ----MNFLR-QFGFRFTTGHGIWAATLIPACIAICMHFDL----LWLGIT TH_1275|M.thermoresistible__bu ----MKSLRNLFGMRFSTGHGIWAAVLIPAVVVLFERLEM----LWLGVV Mflv_0756|M.gilvum_PYR-GCK ----MSRFLSIFGVRFTTGHALWAAVLVPACILIFAQLNL----LWLGIT Mvan_0091|M.vanbaalenii_PYR-1 ----MSRFASIFGLRFTTGHALWAAALIPACILVFARLEL----LWLGIT MAB_3760|M.abscessus_ATCC_1997 MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISLLFGWP---WWAALL MUL_3078|M.ulcerans_Agy99 MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVG MAV_0159|M.avium_104 ------MRPNLTGFSRGSNRRVVGVWVVFVLALASWLLGG----YIAAAV : : . Mb3912c|M.bovis_AF2122/97 LASLGVIVATVTFYGRRITG-WVAAVYAWLRRRRRPPDSSSEPVVGATVK Rv3882c|M.tuberculosis_H37Rv LASLGVIVATVTFYGRRITG-WVAAVYAWLRRRRRPPDSSSEPVVGATVK MMAR_5458|M.marinum_M LVALGVIVATVTFSGRRVTG-WVATVFAWLRRRRRPPDVPSEPVVGATVK MLBr_00042|M.leprae_Br4923 LVVLVVILTLVEFSGRWLSG-WLMALYSFFRRSSKPLDTPSEPVIGATVK MSMEG_0082|M.smegmatis_MC2_155 LGALIALFSVLTIRGLRITG-WVRAIFSWRRRHRSTPDIASEPAVGSTVM TH_1275|M.thermoresistible__bu VAVFIAPASVLTIRGRRLTG-WVAAVFSWRRRHRVPPARPSEPAVGATVA Mflv_0756|M.gilvum_PYR-GCK LAVLIALCALVTIRGRRITG-WIAALFAWRRRHRQPPPAPSEPAVGATVV Mvan_0091|M.vanbaalenii_PYR-1 LGVLIGLASVVTIRGRRLTG-WVAALFAWRRRHRQPPPTPSEPAVGATVI MAB_3760|M.abscessus_ATCC_1997 IAIVSLALVLGRWGGQTVRH-WAVTGFKYLTGRTYR---SSGSIADTPSG MUL_3078|M.ulcerans_Agy99 IAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRR MAV_0159|M.avium_104 AVLVGVALVFVRWWGQPAWS------WAVLWRRGRRPIDWSAPITVANNR . * : . . Mb3912c|M.bovis_AF2122/97 PG-DHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEEL Rv3882c|M.tuberculosis_H37Rv PG-DHVAVRWQGEFLVAVIELIPRPFTPTVIVDGQAHTDDMLDTGLVEEL MMAR_5458|M.marinum_M PG-DHVAVRWRRDHLIAVIELKPRPFTPTVIVDGKAHTDDVLDTRLLEDL MLBr_00042|M.leprae_Br4923 PA-DQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHL MSMEG_0082|M.smegmatis_MC2_155 PG-DHVAVRWQGDYLIAVIELVPRPFTPTVIVNGSAMTDDVVNTKLVERL TH_1275|M.thermoresistible__bu PG-DHVAVRWQGDHLVSAIELVPRPFTPTVLVNGKAFTDDLLDTRLVEQL Mflv_0756|M.gilvum_PYR-GCK PG-DHVALRWQHGYLVSAIELIPRPFTPTVIVNGEAFTDDVIDSRQLEKL Mvan_0091|M.vanbaalenii_PYR-1 PG-DHVALRWQDDYLVSVIELVPRPFTPTVIVNGEAFTDDVVETRLVEDL MAB_3760|M.abscessus_ATCC_1997 QD-SWTGTRWENGKLITVLEISATQRHPSVITPDHCATDSLVPLRVLREC MUL_3078|M.ulcerans_Agy99 FGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAEN MAV_0159|M.avium_104 SG---GGVRVQDGVAVVAVQLLGRAHRATLVTGSVTVETENVLDVVELAP * . : .: : .: : Mb3912c|M.bovis_AF2122/97 LSVHCPDLE-ADIVSAGYRVGNTAAPDVVSLYQQ------VIGTDPAPAN Rv3882c|M.tuberculosis_H37Rv LSVHCPDLE-ADIVSAGYRVGNTAAPDVVSLYQQ------VIGTDPAPAN MMAR_5458|M.marinum_M LSVHCPDLE-ADVVSAGYRVGNTASEEVVSLYQR------VIGADPAPAN MLBr_00042|M.leprae_Br4923 LSVHCPDLE-AVVVSAGYRVGHVASLDVVNLYQQ------VIGADPAPAH MSMEG_0082|M.smegmatis_MC2_155 LEAHCPDLE-ADVVSAGYRVGKTAPASLIALYEQ------VVGPYPAPAN TH_1275|M.thermoresistible__bu LTAHCPDLE-ADIVSAGYRVGKTAPASLLALYEQ------VLGPYPAPAN Mflv_0756|M.gilvum_PYR-GCK LAAYCPDLE-ADIVSAGYRVGRTAPAALVGLYEQ------VVGPYPAPAR Mvan_0091|M.vanbaalenii_PYR-1 LTAYCPDLE-ADIVSAGYRVGKTAPAALVALYEQ------VVGPYPAPAS MAB_3760|M.abscessus_ATCC_1997 MHQNDIELESIDVISNGQRT--AQGTVLRGGYDR------LVGPLPAVAI MUL_3078|M.ulcerans_Agy99 LRQFDVQLDGVDIMTVEVRGGAEAARASASLDEWGPEEWGMVGESPAANR MAV_0159|M.avium_104 MLHQALGLQLDSISVVTVGSRHGNVGDYPRVYDS------EIGTPPYAGR : *: : : :* * Mb3912c|M.bovis_AF2122/97 RRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDA Rv3882c|M.tuberculosis_H37Rv RRTWIVLRADPERTRKSAQRRDEGVAGLARYLVASATRIADRLASHGVDA MMAR_5458|M.marinum_M RRTWIMLRADPEQTRKSAQRREAGLAGLARYLVASATRIADGLASNGVDA MLBr_00042|M.leprae_Br4923 RRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDA MSMEG_0082|M.smegmatis_MC2_155 RRTWIVLRADPEKTQRSAHRRDSGVSGLARYLVASATRIADQLASNGVDA TH_1275|M.thermoresistible__bu RRTWIVLRADPERTQKSARRRDVGVAGLSRYLVASTTRIADQLASHGVDA Mflv_0756|M.gilvum_PYR-GCK RRTWIVLRADPDKTRKSALRRDVGVSGLAQYVVSSTTRIADHLASNGIDA Mvan_0091|M.vanbaalenii_PYR-1 RRTWIVLRADPDKTRKSALRRNEGVAGLAQYLVSSTTRIADHLASKGVDA MAB_3760|M.abscessus_ATCC_1997 RTVWVVLRFDPGANVDAVFRRGGGRRGAERCAVIATARVRRALAAAHCAS MUL_3078|M.ulcerans_Agy99 RRTWLILRMNPQRNVAAIASRDS----LASTLVTATERLAQVLDGQSCAA MAV_0159|M.avium_104 RETWLIMRLAVIDNAQALRWRTT----VGAAAISVAQRIAGLLRCQGLRA * .*:::* . : * : : *: * : Mb3912c|M.bovis_AF2122/97 VCGRSFDDYDHATDIGFVREKWSMIKGRD-----------AYTAAYAAPG Rv3882c|M.tuberculosis_H37Rv VCGRSFDDYDHATDIGFVREKWSMIKGRD-----------AYTAAYAAPG MMAR_5458|M.marinum_M VCGRSFDDYDRATDIGYVREKWSMIKGAD-----------SYTAAYTAPG MLBr_00042|M.leprae_Br4923 VCGHSFESVDHATDVGFMQEKWSMMRGQN-----------AYSVAYTAPA MSMEG_0082|M.smegmatis_MC2_155 RCCRSFDDYEKATEISYERETWSSIKGRS-----------TFTAAYTAPG TH_1275|M.thermoresistible__bu RCARSFDDLDRATEISFERETWSSIKGRS-----------TFTAAYSAPG Mflv_0756|M.gilvum_PYR-GCK RPARSFDDFDGATEISFERETWSMVKGRS-----------TFTAAYHAPG Mvan_0091|M.vanbaalenii_PYR-1 RPARSFDDFDRATEISFERETWSMVKGRS-----------TFTAAYHAPG MAB_3760|M.abscessus_ATCC_1997 TILQAGQIHRISAEMLRQYAGAPMHEDWSGL---------TLIDSYNVAM MUL_3078|M.ulcerans_Agy99 RPLAADELAEVDSTILAELAPTWSRPGWR--------------------- MAV_0159|M.avium_104 KVANATDLAELDRRLGWDAVSGTVQRWKAIRGEAGWMTTYAYPPQAITSR : : : Mb3912c|M.bovis_AF2122/97 GPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPR--------- Rv3882c|M.tuberculosis_H37Rv GPDVWWSARADHTITRVRVAPGMAPQSTVLLTTADKPKTPR--------- MMAR_5458|M.marinum_M GPDLWWSARADHTITRVRIAPGMPPRSTVLLTTVGKPKTPR--------- MLBr_00042|M.leprae_Br4923 GPDAWWSARADHTITRVRVAPGKTPQATVVLTTLGKPKTPC--------- MSMEG_0082|M.smegmatis_MC2_155 GPDMWWSARADHTITRVRVRPGAAPSSAILLTTLANPTTPR--------- TH_1275|M.thermoresistible__bu GPDVWWSARADHTITRLRVRPGAPPTSTVLLTTLANPTTPR--------- Mflv_0756|M.gilvum_PYR-GCK GPDVWWSARADYTLTRVRIVPGAAPTATVLLTTLANPSTPR--------- Mvan_0091|M.vanbaalenii_PYR-1 GPDVWWSARADHTLTRMRIVPGSAPTTTVLLTTLANPSTPR--------- MAB_3760|M.abscessus_ATCC_1997 GIDPWYIT--DATLTGLWARPTLETSVTVRLRPAAKGRTSVGALVRWATD MUL_3078|M.ulcerans_Agy99 -----HLKHFNGYATSFWVTPADINAETLDEVWLSDAPEVG--------- MAV_0159|M.avium_104 NLSQAWTLRADEVIQNVTVYPDGHCSATITVRTPTPAPTPP--------- : . * :: Mb3912c|M.bovis_AF2122/97 ---------GFARLFGGQRPALQGQHLVANR-----------------HC Rv3882c|M.tuberculosis_H37Rv ---------GFARLFGGQRPALQGQHLVANR-----------------HC MMAR_5458|M.marinum_M ---------GFSRLFGSQRPALEGQTLVANH-----------------HC MLBr_00042|M.leprae_Br4923 ---------GFYRLHGAQQPALLGRSFVAYQ-----------------HC MSMEG_0082|M.smegmatis_MC2_155 ---------GFSCLFGGQRAALQGIVPVSDK-----------------HY TH_1275|M.thermoresistible__bu ---------GFSCLFGGQRAALEGLSPVTDK-----------------HH Mflv_0756|M.gilvum_PYR-GCK ---------GFSCLYGGQRAALLGESPVTDR-----------------HY Mvan_0091|M.vanbaalenii_PYR-1 ---------GFSCLFGGQRAALLGENPVTDR-----------------HY MAB_3760|M.abscessus_ATCC_1997 EQLPVRHSTGMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEMSNEELDGI MUL_3078|M.ulcerans_Agy99 -------------------------------------------------- MAV_0159|M.avium_104 --------SVILRRLNGEQAAAAAANMCGPRPHLRG----LRRSRLPAEL Mb3912c|M.bovis_AF2122/97 QLPIGSAGVLVGETVNRCPVYMPFDD---VDIALNLGDAQTFTQFVVRAA Rv3882c|M.tuberculosis_H37Rv QLPIGSAGVLVGETVNRCPVYMPFDD---VDIALNLGDAQTFTQFVVRAA MMAR_5458|M.marinum_M QLPIGSAGVLIGETVNRRPVYMPFDD---VDATVNLGDAQTFTQFAVRSA MLBr_00042|M.leprae_Br4923 QMPIGSAGVLVGETVNRCSVYMPFDD---VDVSVSLGDVQTFTQFVVRAA MSMEG_0082|M.smegmatis_MC2_155 DLPIGSAGVLVGETADRYPVYMPFDN---VDVSINLGDARLFTQFVIRSA TH_1275|M.thermoresistible__bu ELPIGSAGVLVGETVDRYPVYMPFDD---VDVSINLGDARLFTQFVVRSA Mflv_0756|M.gilvum_PYR-GCK ELPIGSAGVLVGETADRYPVYMPFDD---TDVSINLGNARLFTQFVVRSA Mvan_0091|M.vanbaalenii_PYR-1 ELPIGSAGVLVGETADRYPVYMPFDD---VDVSINLGNARLFTQFVVRSA MAB_3760|M.abscessus_ATCC_1997 HLPTSGCGQLIGSDMSGRAIATRLSGQ-GVHTVVVRAELYVCQQVVLRAV MUL_3078|M.ulcerans_Agy99 -ATVLTLRLVMRAGEPRLSAWVRYHS----------------DERLPKEL MAV_0159|M.avium_104 ITEIGPSGVLIGKLPNGDRLLMPVTDAGELSRVFVAADDPIAKRIVIRTA :: . . : Mb3912c|M.bovis_AF2122/97 AAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGP---------- Rv3882c|M.tuberculosis_H37Rv AAGAMVTVGPQFEEFARLIGAHIGQEVKVAWPNATTYLGP---------- MMAR_5458|M.marinum_M AAGGVVTVGPHFEQFAGLIGAHVGAEAKVVWPNATTYLGA---------- MLBr_00042|M.leprae_Br4923 AAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLDP---------- MSMEG_0082|M.smegmatis_MC2_155 AAGAVVTLGPQFREFATMINGRVGRTPRIGWPNATTYLGP---------- TH_1275|M.thermoresistible__bu AAGGVVTLLPQFREFASLINARVGPEAKISWPNATTYLGP---------- Mflv_0756|M.gilvum_PYR-GCK AAGANVTLQPQFGEFAGYVNAQIGPTAKVAWPHATTYLRP---------- Mvan_0091|M.vanbaalenii_PYR-1 AAGAAVTLQPQFEEFAGFVNARIGQVAKVAWPHATTYLRP---------- MAB_3760|M.abscessus_ATCC_1997 AIGALVVVYTDRPHMWDVMVTSIGDANRIQFASGPGFIDPRCTLAVVDGM MUL_3078|M.ulcerans_Agy99 SVGLNRLTGRQLAAVRASLPVPSTRAQLVVSS------------------ MAV_0159|M.avium_104 GAGERVCVHTRDMSRWVSVRMPEISVVNSSRPAPRTTVSVVEYAPRRGEG . * : . Mb3912c|M.bovis_AF2122/97 ---------------------------HPGIDRVILR------HNVIGTP Rv3882c|M.tuberculosis_H37Rv ---------------------------HPGIDRVILR------HNVIGTP MMAR_5458|M.marinum_M ---------------------------HPGIDRVILR------HNLVGTP MLBr_00042|M.leprae_Br4923 ---------------------------YPGSERVILK------HDIIGTP MSMEG_0082|M.smegmatis_MC2_155 ---------------------------HQGVGRVILR------PNFIDTP TH_1275|M.thermoresistible__bu ---------------------------HPGIGRVILR------HNFIDTP Mflv_0756|M.gilvum_PYR-GCK ---------------------------QPGVGRVVLR------DNFIATP Mvan_0091|M.vanbaalenii_PYR-1 ---------------------------HPGVGRVMLR------DDFIATP MAB_3760|M.abscessus_ATCC_1997 QPTALPSNCTALHIISSEYD------ALPARPDVIIDQPNGYGDHILLTA MUL_3078|M.ulcerans_Agy99 --------------------------------RELLD------------- MAV_0159|M.avium_104 VEAAISPTPRPATVITVAPAGTTLSEAQRHGFEVIIEQVSPAVVNVSAAG :: Mb3912c|M.bovis_AF2122/97 RHRQLPIRRVSPPEESRYQMALPK----- Rv3882c|M.tuberculosis_H37Rv RHRQLPIRRVSPPEESRYQMALPK----- MMAR_5458|M.marinum_M RHRKLPIRRVSPPEESRFQMALPK----- MLBr_00042|M.leprae_Br4923 RHRKLPIRRISPPEEGHYQMVLPKSSYEL MSMEG_0082|M.smegmatis_MC2_155 RHRQLPIQLINPREESRYQMALEQ----- TH_1275|M.thermoresistible__bu RHRQLPIRLINPREESRYQMALEG----- Mflv_0756|M.gilvum_PYR-GCK RHKELPIRLINPREESRYQMALEP----- Mvan_0091|M.vanbaalenii_PYR-1 RHKQLPIRLINPREESRYQMVLEP----- MAB_3760|M.abscessus_ATCC_1997 GGETIQVRLVTVSDELAYLGRPIQAFAQ- MUL_3078|M.ulcerans_Agy99 -HDELELPVGQTQEHATSATTGQ------ MAV_0159|M.avium_104 KNWLVEMDMFRAEHRYVSLEPVSMSVGM- : : ..