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TVLRALWRQNFPVARPVGHRDLSTGVPFVITSWIHGTVIHTECDAQRLTAPERLNLGFQVARTLANLHQI PPAAVGLLPPRTGHIDRQLAGLSDVWTWAGTGSVHDSSWRAIRARLVERRPQRRTRLTLVHGDFRLANLV LAEDAIRAIVDWDWCTIGDPIADLAWLLMDWRSPRELASCLPNPTRAGGFPTRGEMVEAYRQATGCSLDD LPYHRAMAHWRAATLLQAEATRQTAHVLDEETPALDVDDVDDTIADLFSGAASFLRAAK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5075 | - | - | 100% (270) | phosphotransferase |
| M. avium 104 | MAV_0316 | - | 7e-18 | 27.47% (233) | phosphotransferase enzyme family protein |
| M. avium 104 | MAV_3946 | - | 3e-17 | 28.37% (208) | phosphotransferase enzyme family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3787c | fadE36 | 8e-18 | 27.20% (261) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1204 | - | 6e-17 | 27.92% (240) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | Rv3761c | fadE36 | 8e-18 | 27.20% (261) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4589c | - | 1e-18 | 27.78% (270) | putative phosphotransferase |
| M. marinum M | MMAR_0155 | fadE36_1 | 4e-25 | 31.65% (237) | acyl-CoA dehydrogenase FadE36_1 |
| M. smegmatis MC2 155 | MSMEG_6337 | - | 3e-17 | 29.18% (233) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_3925 | - | 3e-53 | 38.26% (264) | PUTATIVE putative acyl-CoA dehydrogenase FadE36_1 |
| M. ulcerans Agy99 | MUL_4942 | fadE36_1 | 3e-25 | 31.65% (237) | acyl-CoA dehydrogenase FadE36_1 |
| M. vanbaalenii PYR-1 | Mvan_5603 | - | 4e-18 | 29.60% (277) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1204|M.gilvum_PYR-GCK ---------MT---ELEGLDLAALDRHLREVG-VPRSGELRAELIAGGRS
Mvan_5603|M.vanbaalenii_PYR-1 ---------MT---ELEGLDLAALDRHLCDVG-VPRSGELRAEFISGGRS
MSMEG_6337|M.smegmatis_MC2_155 ---------MT---SLEGLDLDALDRHLRAEG-IARAGDLRAELIAGGRS
Mb3787c|M.bovis_AF2122/97 ---------MTSVDRLDGLDLGALDRYLRSLG-IGRDGELRGELISGGRS
Rv3761c|M.tuberculosis_H37Rv ---------MTSVDRLDGLDLGALDRYLRSLG-IGRDGELRGELISGGRS
MMAR_0155|M.marinum_M -----MPGPMS--EDIPGVHAEAVSRWLVTLG-HQVAAPLRFQRIGLGQS
MUL_4942|M.ulcerans_Agy99 ---------MS--EDIPGVHAHAVSRWLVTLG-HQVAAPLRFQRIGLGQA
MAB_4589c|M.abscessus_ATCC_199 MHKDVSSDSDGPTGDAASLDADAIPTSLSEYLNRELGEQVSVRRLSAGHS
MAV_5075|M.avium_104 --------------------------------------------------
TH_3925|M.thermoresistible__bu ---MTDTSTRAAEPARSMCDRPAAVAQWLMRNGQSVQEPVTVTRVGFGQS
Mflv_1204|M.gilvum_PYR-GCK NLTFLVGDDAS-EWVLRRPPLHGLTPSAHDMAREYKVVAALAGTKVPVAR
Mvan_5603|M.vanbaalenii_PYR-1 NLTFLVFDDAS-KWVLRRPPLHGLTPSAHDMAREYRVVAALADTAVPVAR
MSMEG_6337|M.smegmatis_MC2_155 NLTFLVFDDAS-KWVLRRPPLHGLTPSAHDMAREYRVVAALAGTPVPVAR
Mb3787c|M.bovis_AF2122/97 NLTFRVYDDAS-SWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPVAR
Rv3761c|M.tuberculosis_H37Rv NLTFRVYDDAS-SWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPVAR
MMAR_0155|M.marinum_M NLTYRVTDAAGRAWVLRRPPLGHLLASAHDVVREARIMAALAETDVPVPR
MUL_4942|M.ulcerans_Agy99 NLTYRVTDAAGRAWVLRHPPLGHLLASAHDVVREARIMAALAETDVPVPR
MAB_4589c|M.abscessus_ATCC_199 NLTYVVTGSSGTQWILRRPPFGRLQAGAHDVMREYRVLDALSTAQVRVPR
MAV_5075|M.avium_104 ----------------------------------MTVLRALWRQNFPVAR
TH_3925|M.thermoresistible__bu NITSCVSDGAGREWILREPPPGAAVGSAHDVHREARIIAALESSGIPVPR
:: ** . *.*
Mflv_1204|M.gilvum_PYR-GCK AVTMSDDDSVLGAPFQMVERVAGLVVRHTPQLAALGDETVISNVVDSLIQ
Mvan_5603|M.vanbaalenii_PYR-1 AVTMRNDDSVLGAPFQMVEYVAGRVVRHTDQLAALGDRATIEKCVDALIK
MSMEG_6337|M.smegmatis_MC2_155 AVTMRNDDSVLGAPFQMVDHVDGRVVRTAAELAALGDQTVIDNCIDALIK
Mb3787c|M.bovis_AF2122/97 TISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDALIR
Rv3761c|M.tuberculosis_H37Rv TISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDALIR
MMAR_0155|M.marinum_M ILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQ-IALSLPR
MUL_4942|M.ulcerans_Agy99 ILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQ-IALSLPR
MAB_4589c|M.abscessus_ATCC_199 VTLASTDAEIFGAPFYLMERQDGEVIRDVSPEWFVG--SARRELVLDLAV
MAV_5075|M.avium_104 PVGHRDLS--TGVPFVITSWIHGTVIHTECDAQRLTAPERLN-LGFQVAR
TH_3925|M.thermoresistible__bu VVGMGRSP--DGSPFFVMERVNGRALESEQDAGPLTPAQRQQ-IGRQVAT
*: : . * .: : :
Mflv_1204|M.gilvum_PYR-GCK VLADLHEVDPESVGLGDFGKASGYLERQVRRWGSQWDLVKRD-DDPSDAD
Mvan_5603|M.vanbaalenii_PYR-1 VLADLHSVDPDAVGLSDFGKPSGYLERQVRRWGSQWDLVRRA-DDPCDAD
MSMEG_6337|M.smegmatis_MC2_155 ALSDLHAVDPYAVGLGDFGKPDGYLERQVRRWGSQWEHVRLP-DDARDDD
Mb3787c|M.bovis_AF2122/97 VLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVRLP-DDHRDAD
Rv3761c|M.tuberculosis_H37Rv VLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVRLP-DDHRDAD
MMAR_0155|M.marinum_M TLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSKTR-ELP---E
MUL_4942|M.ulcerans_Agy99 TLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSKTR-ELP---E
MAB_4589c|M.abscessus_ATCC_199 ALAEIHNADPTRLVEAKLGRESGYLARQLKTWGGQWESIKELPTGRDLQD
MAV_5075|M.avium_104 TLANLHQIPPAAVGLLPP--RTGHIDRQLAGLSDVWTWAGTG--SVHDSS
TH_3925|M.thermoresistible__bu ILGRLHTLDTGRLGLPEP--RSPYLERQIRRVTQAWDVYGRD--TRHDAG
* :* : : **: *
Mflv_1204|M.gilvum_PYR-GCK VRKLHQRLAESVPEQ-SRASIVHGDYRIDNTILDADDPTKVAAVLDWEMS
Mvan_5603|M.vanbaalenii_PYR-1 VRRLHERLSAALPPQ-SRSSIVHGDYRIDNTILDAEDPTKVVAVLDWEMS
MSMEG_6337|M.smegmatis_MC2_155 VRRLHAALADAVPPQ-SGTSIVHGDYRIDNTVLDAEDATVVRAVLDWEMS
Mb3787c|M.bovis_AF2122/97 ISRLHLALQQAIPQQ-SRTSIVHGDYRIDNTILDTDDPCHVRAVVDWELS
Rv3761c|M.tuberculosis_H37Rv ISRLHLALQQAIPQQ-SRTSIVHGDYRIDNTILDTDDPCHVRAVVDWELS
MMAR_0155|M.marinum_M LDDLTRRLVAAAPEQ-REISLVHGDFHLRN-LITSPETGAVVATLDWELS
MUL_4942|M.ulcerans_Agy99 LDDLTRRLVAAAPEQ-REISLVHGDFHLRN-LITSPETGAVVATLDWELS
MAB_4589c|M.abscessus_ATCC_199 HTTITAWLTENYPGD-RPAAVVHGDYKLDN-VLVDPATARITAVLDWEMA
MAV_5075|M.avium_104 WRAIRARLVERRPQRRTRLTLVHGDFRLANLVLAEDA---IRAIVDWDWC
TH_3925|M.thermoresistible__bu WQRLRDGLAQSMPARSAPPVIMHGDLRLSNMLVDGGE---VTAVLDWELA
: * * ::*** :: * :: : * :**: .
Mflv_1204|M.gilvum_PYR-GCK TLGDPLSDAALMCVYRLPAFN-EVHDDAA---WACDLMPPTDDLAQRYAL
Mvan_5603|M.vanbaalenii_PYR-1 TLGDPLSDAALMCVYRHPMFN-MVHADAA---WASELIPDADALADKYSR
MSMEG_6337|M.smegmatis_MC2_155 TLGDPLSDAALMCVYRNPMFG-HIHTDAA---WSSDLVPPADELADRYSK
Mb3787c|M.bovis_AF2122/97 TLGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYSL
Rv3761c|M.tuberculosis_H37Rv TLGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYSL
MMAR_0155|M.marinum_M TLGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYLE
MUL_4942|M.ulcerans_Agy99 TLGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYLE
MAB_4589c|M.abscessus_ATCC_199 TVGDPLADLGYLLYMTPEPGGEVAMSELTGSVTAQEGCPSHTEIAQAYRE
MAV_5075|M.avium_104 TIGDPIADLAWLLMDWRSPRELASCLPNP---TRAGGFPTRGEMVEAYRQ
TH_3925|M.thermoresistible__bu AIGDPLADLAWLLDDWRAPEEPGIVMPSP---TRAGGFPDRDEMIEIYHA
::***::* . : . * : *
Mflv_1204|M.gilvum_PYR-GCK ASGKPLDHWD-----FYMALGYFKIAIIAAGIAYRARMGGGVA---EGTD
Mvan_5603|M.vanbaalenii_PYR-1 AAGQPLDHWD-----FYMALAYFKLAIIGAGIAYRAREAG-VV---DDTD
MSMEG_6337|M.smegmatis_MC2_155 VSGRDLAHWD-----FYMALAYFKLAIIAAGIDYRRREGA------DGPE
Mb3787c|M.bovis_AF2122/97 VSGQPLGHWE-----FYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAAE
Rv3761c|M.tuberculosis_H37Rv VSGQPLGHWE-----FYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAAE
MMAR_0155|M.marinum_M ETGRDPAALQ-----YWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTPT
MUL_4942|M.ulcerans_Agy99 ETGRDPAALQ-----YWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTPT
MAB_4589c|M.abscessus_ATCC_199 ARSGDQSYWTPEDLVYYQVLGGWKLATLLE-VSYQRHLAGTTDDPFFAEL
MAV_5075|M.avium_104 ATGCSLDDLP-----YHRAMAHWRAATLLQAEATRQTAHVLDEETPALDV
TH_3925|M.thermoresistible__bu VSGVPVDGID-----YYRAFSQWRAAGLLQGVLVRRRKGQMGDHG-AVDL
. : .:. :: * : :
Mflv_1204|M.gilvum_PYR-GCK EVDRAVRPFVAAGLHILS-----------
Mvan_5603|M.vanbaalenii_PYR-1 KVGEAVAPLIAAGLSQLA-----------
MSMEG_6337|M.smegmatis_MC2_155 QVGEAVAPMIAAGLAALG-----------
Mb3787c|M.bovis_AF2122/97 SVPDVVAPLIARGLAEIAKKSG-------
Rv3761c|M.tuberculosis_H37Rv SVPDVVAPLIARGLAEIAKKSG-------
MMAR_0155|M.marinum_M VAWIDARVHMAREIADAAGMNQVSDSAS-
MUL_4942|M.ulcerans_Agy99 VAWIDARVHMAREIADAAGMNQVSDSAF-
MAB_4589c|M.abscessus_ATCC_199 DEGVPRLLSVARSLIPAAG----------
MAV_5075|M.avium_104 DDVDDTIADLFSGAASFLRAAK-------
TH_3925|M.thermoresistible__bu EQLDSSIATLLSSAAEHLARCTGAGPRTG
: