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PGPMSEDIPGVHAEAVSRWLVTLGHQVAAPLRFQRIGLGQSNLTYRVTDAAGRAWVLRRPPLGHLLASAH DVVREARIMAALAETDVPVPRILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQIALSLPR TLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSKTRELPELDDLTRRLVAAAPEQREISLVHGD FHLRNLITSPETGAVVATLDWELSTLGDPLADMGSLLTYWMEPGESGVGDFAPSTLDGFPDRAEMTRLYL EETGRDPAALQYWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTPTVAWIDARVHMAREIADAAGMNQVS DSAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0155 | fadE36_1 | - | 100% (355) | acyl-CoA dehydrogenase FadE36_1 |
| M. marinum M | MMAR_5304 | fadE36 | 1e-44 | 36.59% (328) | acyl-CoA dehydrogenase FadE36 |
| M. marinum M | MMAR_5325 | - | 6e-36 | 32.59% (316) | hypothetical protein MMAR_5325 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3787c | fadE36 | 2e-45 | 37.08% (329) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1204 | - | 1e-47 | 37.62% (311) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | Rv3761c | fadE36 | 2e-45 | 37.08% (329) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4589c | - | 5e-53 | 37.85% (362) | putative phosphotransferase |
| M. avium 104 | MAV_0316 | - | 2e-45 | 36.25% (331) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_6337 | - | 1e-47 | 37.69% (329) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_3925 | - | 9e-54 | 38.33% (300) | PUTATIVE putative acyl-CoA dehydrogenase FadE36_1 |
| M. ulcerans Agy99 | MUL_4942 | fadE36_1 | 0.0 | 99.14% (350) | acyl-CoA dehydrogenase FadE36_1 |
| M. vanbaalenii PYR-1 | Mvan_5603 | - | 2e-46 | 37.70% (313) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0155|M.marinum_M -------MPGPMSEDIPGVHAEAVSRWLVT-LGHQVAAPLRFQRIGLGQS
MUL_4942|M.ulcerans_Agy99 -----------MSEDIPGVHAHAVSRWLVT-LGHQVAAPLRFQRIGLGQA
Mflv_1204|M.gilvum_PYR-GCK ---------MT---ELEGLDLAALDRHLRE-VGVPRSGELRAELIAGGRS
Mvan_5603|M.vanbaalenii_PYR-1 ---------MT---ELEGLDLAALDRHLCD-VGVPRSGELRAEFISGGRS
MSMEG_6337|M.smegmatis_MC2_155 ---------MT---SLEGLDLDALDRHLRA-EGIARAGDLRAELIAGGRS
Mb3787c|M.bovis_AF2122/97 ---------MTSVDRLDGLDLGALDRYLRS-LGIGRDGELRGELISGGRS
Rv3761c|M.tuberculosis_H37Rv ---------MTSVDRLDGLDLGALDRYLRS-LGIGRDGELRGELISGGRS
MAV_0316|M.avium_104 ---------MTSADQLEGLDLAALDSYLRS-LGIGRDGELRAEFISGGRS
TH_3925|M.thermoresistible__bu --MTDTSTRAAEPARSMCDRPAAVAQWLMR-NGQSVQEPVTVTRVGFGQS
MAB_4589c|M.abscessus_ATCC_199 MHKDVSSDSDGPTGDAASLDADAIPTSLSEYLNRELGEQVSVRRLSAGHS
*: * . : :. *::
MMAR_0155|M.marinum_M NLTYRVTDAAGRAWVLRRPPLGHLLASAHDVVREARIMAALAETDVPVPR
MUL_4942|M.ulcerans_Agy99 NLTYRVTDAAGRAWVLRHPPLGHLLASAHDVVREARIMAALAETDVPVPR
Mflv_1204|M.gilvum_PYR-GCK NLTFLVGDDAS-EWVLRRPPLHGLTPSAHDMAREYKVVAALAGTKVPVAR
Mvan_5603|M.vanbaalenii_PYR-1 NLTFLVFDDAS-KWVLRRPPLHGLTPSAHDMAREYRVVAALADTAVPVAR
MSMEG_6337|M.smegmatis_MC2_155 NLTFLVFDDAS-KWVLRRPPLHGLTPSAHDMAREYRVVAALAGTPVPVAR
Mb3787c|M.bovis_AF2122/97 NLTFRVYDDAS-SWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPVAR
Rv3761c|M.tuberculosis_H37Rv NLTFRVYDDAS-SWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPVAR
MAV_0316|M.avium_104 NLTFRVYDDAT-SWLVRRPPLHGLTPSAHDMAREYRVVAALQDTPVPVAR
TH_3925|M.thermoresistible__bu NITSCVSDGAGREWILREPPPGAAVGSAHDVHREARIIAALESSGIPVPR
MAB_4589c|M.abscessus_ATCC_199 NLTYVVTGSSGTQWILRRPPFGRLQAGAHDVMREYRVLDALSTAQVRVPR
*:* * . : *::*.** .***: ** ::: ** : : *.*
MMAR_0155|M.marinum_M ILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQ-IALSLPR
MUL_4942|M.ulcerans_Agy99 ILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQ-IALSLPR
Mflv_1204|M.gilvum_PYR-GCK AVTMSDDDSVLGAPFQMVERVAGLVVRHTPQLAALGDETVISNVVDSLIQ
Mvan_5603|M.vanbaalenii_PYR-1 AVTMRNDDSVLGAPFQMVEYVAGRVVRHTDQLAALGDRATIEKCVDALIK
MSMEG_6337|M.smegmatis_MC2_155 AVTMRNDDSVLGAPFQMVDHVDGRVVRTAAELAALGDQTVIDNCIDALIK
Mb3787c|M.bovis_AF2122/97 TISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDALIR
Rv3761c|M.tuberculosis_H37Rv TISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDALIR
MAV_0316|M.avium_104 TIGLCEDESVLGAPFQIVEFVAGQVVRRRAQLESF-SHTVIEGCVDSLIR
TH_3925|M.thermoresistible__bu VVGMGR--SPDGSPFFVMERVNGRALESEQDAGPLTPAQRQQ-IGRQVAT
MAB_4589c|M.abscessus_ATCC_199 VTLASTDAEIFGAPFYLMERQDGEVIR--DVSPEWFVGSARRELVLDLAV
. :*: ::: * .: :
MMAR_0155|M.marinum_M TLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSKTRELPELDDL
MUL_4942|M.ulcerans_Agy99 TLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSKTRELPELDDL
Mflv_1204|M.gilvum_PYR-GCK VLADLHEVDPESVGLGDFGKASGYLERQVRRWGSQWDLVKRDDDPSDADV
Mvan_5603|M.vanbaalenii_PYR-1 VLADLHSVDPDAVGLSDFGKPSGYLERQVRRWGSQWDLVRRADDPCDADV
MSMEG_6337|M.smegmatis_MC2_155 ALSDLHAVDPYAVGLGDFGKPDGYLERQVRRWGSQWEHVRLPDDARDDDV
Mb3787c|M.bovis_AF2122/97 VLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVRLPDDHRDADI
Rv3761c|M.tuberculosis_H37Rv VLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVRLPDDHRDADI
MAV_0316|M.avium_104 VLVDLHSVDPDAVGLADFGKPSGYLERQVRRWGSQWALVRLPEDRRDADV
TH_3925|M.thermoresistible__bu ILGRLHTLDTGRLGLPEPRSP--YLERQIRRVTQAWDVYGR-DTRHDAGW
MAB_4589c|M.abscessus_ATCC_199 ALAEIHNADPTRLVEAKLGRESGYLARQLKTWGGQWESIKELPTGRDLQD
* :* * : . * **:: *
MMAR_0155|M.marinum_M TRR---LVAAAPEQREI-SLVHGDFHLRN-LITSPETGAVVATLDWELST
MUL_4942|M.ulcerans_Agy99 TRR---LVAAAPEQREI-SLVHGDFHLRN-LITSPETGAVVATLDWELST
Mflv_1204|M.gilvum_PYR-GCK RKLHQRLAESVPEQSRA-SIVHGDYRIDNTILDADDPTKVAAVLDWEMST
Mvan_5603|M.vanbaalenii_PYR-1 RRLHERLSAALPPQSRS-SIVHGDYRIDNTILDAEDPTKVVAVLDWEMST
MSMEG_6337|M.smegmatis_MC2_155 RRLHAALADAVPPQSGT-SIVHGDYRIDNTVLDAEDATVVRAVLDWEMST
Mb3787c|M.bovis_AF2122/97 SRLHLALQQAIPQQSRT-SIVHGDYRIDNTILDTDDPCHVRAVVDWELST
Rv3761c|M.tuberculosis_H37Rv SRLHLALQQAIPQQSRT-SIVHGDYRIDNTILDTDDPCHVRAVVDWELST
MAV_0316|M.avium_104 ERLHSGLGQAIPQQSRT-SIVHGDYRIDNTILDADDPTKVRAVVDWELST
TH_3925|M.thermoresistible__bu QRLRDGLAQSMPARSAPPVIMHGDLRLSNMLVDGGE---VTAVLDWELAA
MAB_4589c|M.abscessus_ATCC_199 HTTITAWLTENYPGDRPAAVVHGDYKLDNVLVDPATAR-ITAVLDWEMAT
::*** :: * :: : *.:***:::
MMAR_0155|M.marinum_M LGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYLEE
MUL_4942|M.ulcerans_Agy99 LGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYLEE
Mflv_1204|M.gilvum_PYR-GCK LGDPLSDAALMCVYRLPAFN-EVHDDAA---WACDLMPPTDDLAQRYALA
Mvan_5603|M.vanbaalenii_PYR-1 LGDPLSDAALMCVYRHPMFN-MVHADAA---WASELIPDADALADKYSRA
MSMEG_6337|M.smegmatis_MC2_155 LGDPLSDAALMCVYRNPMFG-HIHTDAA---WSSDLVPPADELADRYSKV
Mb3787c|M.bovis_AF2122/97 LGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYSLV
Rv3761c|M.tuberculosis_H37Rv LGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYSLV
MAV_0316|M.avium_104 LGDPLSDAALMCVYRDPALDLIVNAQAA---WTSPLLPTADELADRYSLV
TH_3925|M.thermoresistible__bu IGDPLADLAWLLDDWRAPEEPGIVMPSP---TRAGGFPDRDEMIEIYHAV
MAB_4589c|M.abscessus_ATCC_199 VGDPLADLGYLLYMTPEPGGEVAMSELTGSVTAQEGCPSHTEIAQAYREA
:****:* . : . * : *
MMAR_0155|M.marinum_M TGRD-----PAALQYWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTPTV
MUL_4942|M.ulcerans_Agy99 TGRD-----PAALQYWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTPTV
Mflv_1204|M.gilvum_PYR-GCK SGKP-----LDHWDFYMALGYFKIAIIAAGIAYRARMGGGVA---EGTDE
Mvan_5603|M.vanbaalenii_PYR-1 AGQP-----LDHWDFYMALAYFKLAIIGAGIAYRAREAG-VV---DDTDK
MSMEG_6337|M.smegmatis_MC2_155 SGRD-----LAHWDFYMALAYFKLAIIAAGIDYRRREGA------DGPEQ
Mb3787c|M.bovis_AF2122/97 SGQP-----LGHWEFYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAAES
Rv3761c|M.tuberculosis_H37Rv SGQP-----LGHWEFYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAAES
MAV_0316|M.avium_104 AGIP-----LAHWEFYMALAYFKLAIIAAGIDFRRRMSDQARGLGEAAEH
TH_3925|M.thermoresistible__bu SGVP-----VDGIDYYRAFSQWRAAGLLQGVLVRRRKGQMGDHGAVDLEQ
MAB_4589c|M.abscessus_ATCC_199 RSGDQSYWTPEDLVYYQVLGGWKLATLLEVSYQRHLAGTTDDPFFAELDE
. :: .:. :: * : *
MMAR_0155|M.marinum_M AWIDARVHMAREIADAAGMNQVSDSAS
MUL_4942|M.ulcerans_Agy99 AWIDARVHMAREIADAAGMNQVSDSAF
Mflv_1204|M.gilvum_PYR-GCK VDRAVRPFVAAGLHILS----------
Mvan_5603|M.vanbaalenii_PYR-1 VGEAVAPLIAAGLSQLA----------
MSMEG_6337|M.smegmatis_MC2_155 VGEAVAPMIAAGLAALG----------
Mb3787c|M.bovis_AF2122/97 VPDVVAPLIARGLAEIAKKSG------
Rv3761c|M.tuberculosis_H37Rv VPDVVAPLIARGLAEIAKKSG------
MAV_0316|M.avium_104 TPEVVAPLISRGLAELAKLPG------
TH_3925|M.thermoresistible__bu LDSSIATLLSSAAEHLARCTGAGPRTG
MAB_4589c|M.abscessus_ATCC_199 GVPRLLSVARSLIPAAG----------
.