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TTTITPVPQPAAAPERHKGRHWIDDWRPEDPEFWETTGKAIARRNLIFSIFAEHVGFSVWMLWSIVVVHM TAGPHGHPSASGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGRNWTTISAALLLIPCLLLAWAVS HPGIPFGVLVAIAATAGFGGGNFASSMANISFFYPEKDKGWALGLNAAGGNIGVAVVQKVIPPVVIAGGG VALSRAGLFYVPLAVVAAVCAFLFMNNLTEIKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPT LLKTVFGRGDIALAWAFLGAAIGSVIRPLGGKLADRVGGARITAASFVMLAVGAAAALWSVKAVNLPAFF ASFMFLFVATGIGNGSTYRMISRIFKIKGELAGGDPDTMVTMRRQAAGALGVISAVGAFGGFIVPLAYAW SKSQFGSIEPALRFYVVFFLGLLAVTWYCYLRKHNAITRVGI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4892 | narK | - | 100% (463) | nitrite transporter |
| M. avium 104 | MAV_4899 | - | 9e-75 | 36.64% (453) | transporter, major facilitator family protein |
| M. avium 104 | MAV_2079 | - | 3e-68 | 34.87% (456) | transporter, major facilitator family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0273 | narU | 0.0 | 83.59% (463) | putative integral membrane nitrite extrusion protein NARU |
| M. gilvum PYR-GCK | Mflv_3015 | - | 5e-90 | 44.08% (456) | nitrite extrusion protein |
| M. tuberculosis H37Rv | Rv0267 | narU | 0.0 | 83.59% (463) | integral membrane nitrite extrusion protein NarU |
| M. leprae Br4923 | MLBr_00844 | narK | 2e-74 | 35.40% (452) | putative nitrite extrusion protein |
| M. abscessus ATCC 19977 | MAB_3523c | - | 2e-95 | 43.52% (471) | integral membrane nitrite extrusion protein NarK3 |
| M. marinum M | MMAR_0526 | narU | 0.0 | 84.05% (464) | integral membrane nitrite extrusion protein NarU |
| M. smegmatis MC2 155 | MSMEG_0433 | - | 2e-90 | 41.61% (459) | nitrite extrusion protein |
| M. thermoresistible (build 8) | TH_0644 | narK2 | 2e-08 | 25.94% (212) | POSSIBLE NITRATE/NITRITE TRANSPORTER NARK2 |
| M. ulcerans Agy99 | MUL_1189 | narU | 0.0 | 83.41% (464) | integral membrane nitrite extrusion protein NarU |
| M. vanbaalenii PYR-1 | Mvan_3492 | - | 0.0 | 81.42% (452) | nitrite transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3015|M.gilvum_PYR-GCK ------------------------------MTWAFTGVMAKRTRDIDTWD
MAB_3523c|M.abscessus_ATCC_199 -----------------------------MANNTATAPIARRGRWIENWD
MLBr_00844|M.leprae_Br4923 MDQLVLLQAEESLYGPGRRSKTVPIDHRHSLKSSFFRLRLRRACRISHWD
MSMEG_0433|M.smegmatis_MC2_155 ------------------------------------MPTLLKPKRITNWD
MMAR_0526|M.marinum_M --------------------MT----ITPVRQHTAPREQHVGRHWIHDWR
MUL_1189|M.ulcerans_Agy99 --------------------MT----ITPVRQHTAPREQHVGRHWIHDWR
Mb0273|M.bovis_AF2122/97 ------------------MALT----TAPAIDYALPRQQDEGDHWIDDWR
Rv0267|M.tuberculosis_H37Rv ------------------MALT----TAPAIDYALPRQQDEGDHWIDDWR
MAV_4892|M.avium_104 ------------------MTTT----ITPVPQPAAAPERHKGRHWIDDWR
Mvan_3492|M.vanbaalenii_PYR-1 ------------------MTVTDSESTGALATAAPAPERHRGKHWIDDWR
TH_0644|M.thermoresistible__bu --------------------------------------------------
Mflv_3015|M.gilvum_PYR-GCK PEDVQAWEGTGGKAPGKEIAKRNLIWSIVAEHVGFSVWSIWSVMVLFMPQ
MAB_3523c|M.abscessus_ATCC_199 PEDVVAWD-NG----GAKIARRNLIWSVVAEHVGFSVWSIWSVMVLFMPQ
MLBr_00844|M.leprae_Br4923 PEDQAAWEAGN-----KTIARLNLLWSVLTVHLGYSVWTLWPVMELFMPK
MSMEG_0433|M.smegmatis_MC2_155 PEDVAAWEAGN-----KYVARRNLIWSVVAEHIGFSIWSIWSVMVLFMPE
MMAR_0526|M.marinum_M PEDPEFWDTIG-----RPIARRNLVFSIFAEHIGFSVWMLWSIVVVQMMA
MUL_1189|M.ulcerans_Agy99 PEDPEFWDTIG-----RPIARRNLVFSIFAEHIGFTVWMLWSIVVVQMMA
Mb0273|M.bovis_AF2122/97 PEDPVFWETIG-----RPIARRNLIFSIFAEHVGFSVWMLWSIVVVQMTA
Rv0267|M.tuberculosis_H37Rv PEDPVFWETIG-----RPIARRNLIFSIFAEHVGFSVWMLWSIVVVQMTA
MAV_4892|M.avium_104 PEDPEFWETTG-----KAIARRNLIFSIFAEHVGFSVWMLWSIVVVHMTA
Mvan_3492|M.vanbaalenii_PYR-1 PEDPEFWATTG-----KPVARRNLIFSIFAEHIGFSVWLLWSIVVVQMTA
TH_0644|M.thermoresistible__bu --------------------MIGPLSTTYAVDISLS--------------
. : : : .:. :
Mflv_3015|M.gilvum_PYR-GCK D------------VYGIDAAGKFYLVAVPTLVGAFMRIPYTIAPARFGGR
MAB_3523c|M.abscessus_ATCC_199 N------------VYHIDAAGKFFLVAMPTLVGAVLRLPYTFATAWFGGR
MLBr_00844|M.leprae_Br4923 D------------VYGFSAGDKFLLATTATLVGACLRVPYSLATALFGGR
MSMEG_0433|M.smegmatis_MC2_155 A------------VYGFSAGDKFLLGATATLVGSCLRIPYTLATATFGGR
MMAR_0526|M.marinum_M VGAPGHPSHPAASGWALSPSQALCLVAVPSGVGALLRLPYTFAIPVFGGR
MUL_1189|M.ulcerans_Agy99 VGAPGHPSHPAASGWALSPSQALCLVAVPSGVGALLRLPYTFAIPVFGGR
Mb0273|M.bovis_AF2122/97 A-APGHP---AASGWALSASQALCLVAVPSGVGAFLRLPYTFAIPIFGGR
Rv0267|M.tuberculosis_H37Rv A-APGHP---AASGWALSASQALCLVAVPSGVGAFLRLPYTFAIPIFGGR
MAV_4892|M.avium_104 G-PHGHP---SASGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGR
Mvan_3492|M.vanbaalenii_PYR-1 G-ADGSP---AASGFALTTTQALWLVAVPSGVGAFLRLPYTFAVPVFGGR
TH_0644|M.thermoresistible__bu ------------------SAEASMLVATPILVGAVGRIVVGSLTDRYGGR
. * : . **: *: :***
Mflv_3015|M.gilvum_PYR-GCK NWTIVSALLLLIPTVLAYYYMKNPAS-YTTYMVIAAFAGLGGGNFASSMT
MAB_3523c|M.abscessus_ATCC_199 NWTVFSALVLAVPTALTLYFMAHPETSYTTFMIVAAVAGFGGGNFASSMT
MLBr_00844|M.leprae_Br4923 NWAIFSVMVLLIPTIATMVLLAHPGLPLWPYLACAALTGLGGGNFAASMT
MSMEG_0433|M.smegmatis_MC2_155 NWTVFSALVLLIPTVMTVVLMANPGLPLWPYLVCAALAGFGGGNFASSMT
MMAR_0526|M.marinum_M NWTTISASLLVIPCLLLSWAVSHPGIPFVLLTLIAATAGVGGGNFASSMA
MUL_1189|M.ulcerans_Agy99 NWTTISASLLVIPCLLLSWAVSHPGIPFVLLTLIAATAGVGGGNFASSMA
Mb0273|M.bovis_AF2122/97 NWTTVSAALLVIPCLLLAWAVSHPSLPFAVLVVIAATAGFGGGNFASSMA
Rv0267|M.tuberculosis_H37Rv NWTTVSAALLVIPCLLLAWAVSHPSLPFAVLVVIAATAGFGGGNFASSMA
MAV_4892|M.avium_104 NWTTISAALLLIPCLLLAWAVSHPGIPFGVLVAIAATAGFGGGNFASSMA
Mvan_3492|M.vanbaalenii_PYR-1 NWTVISALLLLIPCLGLAWAVSNPDINFAVLLLIAATAGFGGGNFASSMA
TH_0644|M.thermoresistible__bu --AMFIAITLASIVPVLAVGAAGAAGSYPLLLVFGFFLGIAGTIFAVGIP
: . . * . . *..* ** .:.
Mflv_3015|M.gilvum_PYR-GCK NINAFYPQRLKGWALGLNAGGGNIGVPVIQLIGLMVIAAVGNTRPEIVCA
MAB_3523c|M.abscessus_ATCC_199 NINAFYPQRFKGWALGLNAGGGNIGVPVIQVIGLLVIATVGNRSPHWVAA
MLBr_00844|M.leprae_Br4923 NANAFYPHRLKGAAFGLAGGAGNLGVSVIQVVGMLVIASVGDRKPYIVCG
MSMEG_0433|M.smegmatis_MC2_155 NINAFYPQRLKGWALGLNAGGGNIGVPMIQLVGLFVIATAGNRAPYWVCA
MMAR_0526|M.marinum_M NISFFYPEKDKGWALGLNAAGGNIGVAVVQKIIPPIVVAGGGMALARAGL
MUL_1189|M.ulcerans_Agy99 NISFFYPEKDKGWALGLNAAGGNVGVAVVQKIIPPIVVAGGGMALARAGL
Mb0273|M.bovis_AF2122/97 NISFFYPEKDKGWALGLNAAGGNIGVAVVQKIIPPIVVAGSGVALSRAGL
Rv0267|M.tuberculosis_H37Rv NISFFYPEKDKGWALGLNAAGGNIGVAVVQKIIPPIVVAGSGVALSRAGL
MAV_4892|M.avium_104 NISFFYPEKDKGWALGLNAAGGNIGVAVVQKVIPPVVIAGGGVALSRAGL
Mvan_3492|M.vanbaalenii_PYR-1 NISFFYPESEKGWALGLNAAGGNIGVAVAQKIIPVVVTLGAGVALSLAGL
TH_0644|M.thermoresistible__bu FANNWYAPSRRGFATGVFGMG-MVGTALSAFFTPRFVESFG---LFTTHV
. :*. :* * *: . . :*..: . .: . .
Mflv_3015|M.gilvum_PYR-GCK IYLVAISGAAVGAALFMDNLRNQKSNFGALVE----AMRFKHSWVMSFLY
MAB_3523c|M.abscessus_ATCC_199 IYLVLIAFAAVGAALFMDNLADQKTDGRSLID----VMKYRDSWIIAFLY
MLBr_00844|M.leprae_Br4923 LYVVLLIIAGIGAMLFMNDIEHHRIGVNTIRPVLFVVVSTRDSWVLALLY
MSMEG_0433|M.smegmatis_MC2_155 VYLVALAVAGLGAALYMDNLEHHKIDLGAMK----AILGERDTWIISLLY
MMAR_0526|M.marinum_M FYVPLAVVAAVCAFAFMNNLAEAKADVKPVWQS----LRHADTWILALLY
MUL_1189|M.ulcerans_Agy99 FYVPLAVVAAVCAFAFMNNLAEAKADVKPVWQS----LRHVDTWILALLY
Mb0273|M.bovis_AF2122/97 FFVPLAVAAAVCAFLFMNNLTEAKADVKPVWQS----LRHADTWIMSLLY
Rv0267|M.tuberculosis_H37Rv FFVPLAVAAAVCAFLFMNNLTEAKADVKPVWQS----LRHADTWIMSLLY
MAV_4892|M.avium_104 FYVPLAVVAAVCAFLFMNNLTEIKADVKPVWQS----LRHADTWIMSLLY
Mvan_3492|M.vanbaalenii_PYR-1 FYIPFTVAAAVCAFLFMNNLTEAKADVKPVWES----LRHADTWIMSLLY
TH_0644|M.thermoresistible__bu IIAVALGLTALLCLVAMHDSPDFTPNTERVLPKLKAAARLPVTWEMSILY
. :.: . *.: . . : :* :::**
Mflv_3015|M.gilvum_PYR-GCK IGTFGSFIGFSFAFGQVLQINYLAG--------GDTPAQASLHAAQIAFL
MAB_3523c|M.abscessus_ATCC_199 IGTFGSFIGFSFAFGQVLQLNFLAGLAHSGVTPAQAAAQASLHAAQIAFI
MLBr_00844|M.leprae_Br4923 LASFGSFIGFSFAFGQVLETNFVAG--------GQSTAQAALHAAELAFI
MSMEG_0433|M.smegmatis_MC2_155 IGTFGSFIGFAFAFGQVLQINFISG--------GQTPAQASLHAAQIAFI
MMAR_0526|M.marinum_M IGTFGSFIGYSAAFPTLLKTVFDRG----------------DIALGWAFL
MUL_1189|M.ulcerans_Agy99 IGTFGSFIGYSAAFPTLLKTVFDRG----------------DIALGWAFL
Mb0273|M.bovis_AF2122/97 IGTFGSFIGYSAAFPTLLKTVFGRG----------------DIALGWAFL
Rv0267|M.tuberculosis_H37Rv IGTFGSFIGYSAAFPTLLKTVFGRG----------------DIALGWAFL
MAV_4892|M.avium_104 IGTFGSFIGYSAAFPTLLKTVFGRG----------------DIALAWAFL
Mvan_3492|M.vanbaalenii_PYR-1 IGTFGSFIGYSAAFPTLLKAVFDRG----------------DIALMWAFL
TH_0644|M.thermoresistible__bu AIVFGGFVAFSNYLPTYXPSSPACT-------------------------
**.*:.:: :
Mflv_3015|M.gilvum_PYR-GCK GPLLGSISRPFGGKLADRVGGGRITLYVFVAMIFAAGVLVATGVMDDAAA
MAB_3523c|M.abscessus_ATCC_199 GPLLGSLARPFGGWLSDRTGGGKISLYAFIAMIFGAGILVAAGTISDRGA
MLBr_00844|M.leprae_Br4923 GPTLAAVARFWGGRLADRLGGSRVTLVVFGAMVFAAGLLGVLGIIEGSRV
MSMEG_0433|M.smegmatis_MC2_155 GPLLGSLSRVYGGKLADRIGGGRVTLAVFAGMILGAGLLVAVSTVSDGSS
MMAR_0526|M.marinum_M GAGIGSVIRPLGGRLADRVGGARVTAVSFLMLAIGA----------AAAL
MUL_1189|M.ulcerans_Agy99 GAGIGSVIRPLGGRLADRVGGARVTAVSFLMLAIGA----------AAAL
Mb0273|M.bovis_AF2122/97 GAGIGSLVRPLGGKLADRIGGARITAASFVMLAAGA----------AAAL
Rv0267|M.tuberculosis_H37Rv GAGIGSLVRPLGGKLADRIGGARITAASFVMLAAGA----------AAAL
MAV_4892|M.avium_104 GAAIGSVIRPLGGKLADRVGGARITAASFVMLAVGA----------AAAL
Mvan_3492|M.vanbaalenii_PYR-1 GAGIGSVARPLGGKLSDRVGGARITAVSFAMLAIGA----------AGAL
TH_0644|M.thermoresistible__bu ---ITTCTSTPPPRHSTRFGSG----------------------------
: : : * *..
Mflv_3015|M.gilvum_PYR-GCK GAPTSAQMIGYVAGFILLFILSGLGNGSTYKMIPSIFEAKAQGRDDLDKE
MAB_3523c|M.abscessus_ATCC_199 GAPSGSIMTAYVIGFIILFVVSGIGNGSVYKMIPSVFAAKARSAG-LDET
MLBr_00844|M.leprae_Br4923 CPIRGVMMASYFAGFITLFILSGLGNGSVYKMIPTIFEACSHSLGINDDE
MSMEG_0433|M.smegmatis_MC2_155 EAATGLMMSGYVVGFIALFLLSGIGNGSVYKMIPSIFEARSHSLDVSEDE
MMAR_0526|M.marinum_M WSVQIVNLPLFFASFMFLFVATGIGNGSTYRMISRIFKVKGELAG-GDPD
MUL_1189|M.ulcerans_Agy99 WSVQNVNLPLFFASFMFLFVATGIGNGSTYRMISRIFKVKGELAG-GDPD
Mb0273|M.bovis_AF2122/97 WSVQSVNLPVFFVSFMFLFVATGIGNGSSYRMISRIFQVKGEVAG-GDPE
Rv0267|M.tuberculosis_H37Rv WSVQSVNLPVFFVSFMFLFVATGIGNGSSYRMISRIFQVKGEVAG-GDPE
MAV_4892|M.avium_104 WSVKAVNLPAFFASFMFLFVATGIGNGSTYRMISRIFKIKGELAG-GDPD
Mvan_3492|M.vanbaalenii_PYR-1 WSVQAKNMPVFFIAFMFLFVATGIGNGSTYRMISKIFRVKGEDAG-GDPL
TH_0644|M.thermoresistible__bu --------------------PGRSGPAGSWPMCSPPRNPVTTAGS-----
* .. : * . .
Mflv_3015|M.gilvum_PYR-GCK GKAAWSRAMSGALIGFAGAVGALGGVFINVVLRASYVGDAKSATAAFWVF
MAB_3523c|M.abscessus_ATCC_199 ----WSRTMSGALIGVAGAIGALGGVAINLVLRASYLSAAKSATMAFWVF
MLBr_00844|M.leprae_Br4923 CR-DWSRVISGVVIGFVAEVGALGGVGIDLALRESYLNTG-GVTAAFWIF
MSMEG_0433|M.smegmatis_MC2_155 RR-HWSRSMSGALIGFAGAVGALGGVGINMALRQSYLSSG-SATTAFWTF
MMAR_0526|M.marinum_M TMVQMRRQAAG-ALGVISAVGAFGGFLVPLAYAWSKAQFG-NIEPALRFY
MUL_1189|M.ulcerans_Agy99 TMVQMRRQAAG-ALGVISAVGAFGGFLVPLAYAWSKAQFG-NIEPALRFY
Mb0273|M.bovis_AF2122/97 TMVNMRRQAAG-ALGIISSIGAFGGFVVPLAYAWSKVHFG-NIEPALHFY
Rv0267|M.tuberculosis_H37Rv TMVNMRRQAAG-ALGIISSIGAFGGFVVPLAYAWSKVHFG-NIEPALHFY
MAV_4892|M.avium_104 TMVTMRRQAAG-ALGVISAVGAFGGFIVPLAYAWSKSQFG-SIEPALRFY
Mvan_3492|M.vanbaalenii_PYR-1 TMLHMRRQAAG-ALGIISSVGAFGGFIVPLAYAWSKSQFG-NIQPALQFY
TH_0644|M.thermoresistible__bu GRSAITRRSRGHWIGVRSTR------------SHPMCRCGCSTAAACCGR
* * :*. . . . . *
Mflv_3015|M.gilvum_PYR-GCK LAFYVVCAFVTWFVFLRLQEHRAHSGEHIGRTSAPVPVG-----
MAB_3523c|M.abscessus_ATCC_199 LVFYVICAAVTWYAYVRRPMTVSVP--AISSSKNEVAV------
MLBr_00844|M.leprae_Br4923 MLCYAAAGVLTWKMYVCRPLPGNLHDEAANAFAASVGASRTHRG
MSMEG_0433|M.smegmatis_MC2_155 LAFYVLASVVTWFCYVRR--PAAMPVTGTERHAPAIAG------
MMAR_0526|M.marinum_M VVFFLALLFVTWHCYLRSKTPMAQLGV-----------------
MUL_1189|M.ulcerans_Agy99 VVFFLALLFVTWHCYLRSKTPMAQLGV-----------------
Mb0273|M.bovis_AF2122/97 VAFFLALLVVTWYCYLRRTTPMGQVGV-----------------
Rv0267|M.tuberculosis_H37Rv VAFFLALLVVTWYCYLRRTTPMGQVGV-----------------
MAV_4892|M.avium_104 VVFFLGLLAVTWYCYLRKHNAITRVGI-----------------
Mvan_3492|M.vanbaalenii_PYR-1 VGFFIVLLGVTWFFYMRKGTRMAQAGV-----------------
TH_0644|M.thermoresistible__bu --------------------------------------------