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RHDDVFRLNEPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATASADPPVQRV VPGVVVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPL VHTAHTLAAVKNAALAQGDSPEPPLRTVGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVD LDVFRPGDRRAARAALGLPLDEDIVAFVGRIQPLKAPDIVLRAAAKLPGVRIVVAGGPSGTGLASPDGLA LLADELGISARVTFLPPQSRPNLATLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRD GVTGTLVAGHDVDHWADALAGLLRAPAPAAAAMSRAAAAHAATFSWDHTTDALLASYRRAIREYTTERRG VGA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_4664 | - | - | 100% (424) | hypothetical protein MAV_4664 |
M. avium 104 | MAV_4082 | - | 5e-56 | 36.23% (414) | transferase |
M. avium 104 | MAV_1357 | - | 4e-24 | 31.42% (331) | glycogen synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0496 | - | 0.0 | 86.67% (420) | mannosyltransferase |
M. gilvum PYR-GCK | Mflv_0086 | - | 1e-177 | 74.88% (410) | glycosyl transferase, group 1 |
M. tuberculosis H37Rv | Rv0486 | - | 0.0 | 86.67% (420) | mannosyltransferase |
M. leprae Br4923 | MLBr_02443 | - | 0.0 | 87.16% (405) | putative glycosyl transferase |
M. abscessus ATCC 19977 | MAB_4057c | - | 1e-173 | 73.17% (410) | glycosyl transferase |
M. marinum M | MMAR_0812 | - | 0.0 | 84.67% (424) | mannosyltransferase |
M. smegmatis MC2 155 | MSMEG_0933 | - | 0.0 | 79.66% (408) | hypothetical protein MSMEG_0933 |
M. thermoresistible (build 8) | TH_2622 | - | 0.0 | 77.97% (413) | PUTATIVE glycosyl transferase, group 1 |
M. ulcerans Agy99 | MUL_4556 | - | 0.0 | 84.67% (424) | mannosyltransferase |
M. vanbaalenii PYR-1 | Mvan_0827 | - | 1e-179 | 74.88% (422) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0086|M.gilvum_PYR-GCK ---------------------------MRLATDPAGSSSGLPQPRRVAVL Mvan_0827|M.vanbaalenii_PYR-1 ---------------------------MRLATEPASLPSGLPEPRRVAVL MSMEG_0933|M.smegmatis_MC2_155 ---------------------------MRLATD-------LETPRRVAVL TH_2622|M.thermoresistible__bu ---------------------------VRLTTAG---PLDPPIPQRVAVL MMAR_0812|M.marinum_M MRPMRAGAG----------AAGESCKDDGVRPDDVSRLTADAVVRRVALL MUL_4556|M.ulcerans_Agy99 ---MRAGAG----------AAGESCKDDGVRPDDVSRLTADAVVRRVALL Mb0496|M.bovis_AF2122/97 MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL Rv0486|M.tuberculosis_H37Rv MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL MLBr_02443|M.leprae_Br4923 ------------------------------------------------ML MAV_4664|M.avium_104 -----------------------------MRHDDVFRLNE---PRRVAVL MAB_4057c|M.abscessus_ATCC_199 ---------------------------MLSGDEFARRAVAALKPRRIAVL :* Mflv_0086|M.gilvum_PYR-GCK SVHTSPLAQPGTGDAGGMNVYVLQTSLELARRGVEVEIFTRATSSADQPI Mvan_0827|M.vanbaalenii_PYR-1 SVHTSPLAQPGTGDAGGMNVYVLQTALELANRGVDVEIFTRATSSADQPV MSMEG_0933|M.smegmatis_MC2_155 SVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVEVEVFTRATSSADAPV TH_2622|M.thermoresistible__bu SVHTSPLHQPGTGDAGGLNVYVLQSALELARRGVEVEIFTRATSSADRPV MMAR_0812|M.marinum_M AVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPV MUL_4556|M.ulcerans_Agy99 AVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPV Mb0496|M.bovis_AF2122/97 AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV Rv0486|M.tuberculosis_H37Rv AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV MLBr_02443|M.leprae_Br4923 AVHTSPLAQPGIGDAGGMNVYVLQSALHLARRGIEVEIFTRATASADPPI MAV_4664|M.avium_104 AVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATASADPPV MAB_4057c|M.abscessus_ATCC_199 SVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVAVDIFTRATSSSDEPV :****** *** *****:***:**::*.**.**: *::*****:*:* *: Mflv_0086|M.gilvum_PYR-GCK VSVAPGVVVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDI Mvan_0827|M.vanbaalenii_PYR-1 VPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDI MSMEG_0933|M.smegmatis_MC2_155 VPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDV TH_2622|M.thermoresistible__bu VPVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFTAGVLRAEATHEPGYYDI MMAR_0812|M.marinum_M VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDI MUL_4556|M.ulcerans_Agy99 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDI Mb0496|M.bovis_AF2122/97 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI Rv0486|M.tuberculosis_H37Rv VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI MLBr_02443|M.leprae_Br4923 VWVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGYYDI MAV_4664|M.avium_104 QRVVPGVVVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDI MAB_4057c|M.abscessus_ATCC_199 VSVTDGVTVRNIVAGPFEGLDKYDLPTQLCAFTAGVLRAEAVHEPGYYNL *. ** ***:********** *********:******** ****:*:: Mflv_0086|M.gilvum_PYR-GCK LHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDTPEPPMRA Mvan_0827|M.vanbaalenii_PYR-1 VHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDAPEPPMRS MSMEG_0933|M.smegmatis_MC2_155 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAAGDAPEPPLRA TH_2622|M.thermoresistible__bu VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAEGDSPEPPLRV MMAR_0812|M.marinum_M VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRT MUL_4556|M.ulcerans_Agy99 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRT Mb0496|M.bovis_AF2122/97 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT Rv0486|M.tuberculosis_H37Rv VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT MLBr_02443|M.leprae_Br4923 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDAAEPPLRS MAV_4664|M.avium_104 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAQGDSPEPPLRT MAB_4057c|M.abscessus_ATCC_199 VHSHYWLSGQAGWLARDRWGVPLVHTAHTLAAVKNQTLAEGDRPEPALRG :*********.**** ***.*************** :** ** .**.:* Mflv_0086|M.gilvum_PYR-GCK IGEQQVVDEADRLIVNTEHEAQQLVSLHHADPGRIDVVHPGVDLATFTPG Mvan_0827|M.vanbaalenii_PYR-1 IGEQQVVDAADRLIVNTEHEAQQLVSLHQADPARIDVVHPGVDLATFTPG MSMEG_0933|M.smegmatis_MC2_155 VGEQQVVDEADRLIVNTEVEAQQLVSLHNADRSRIDVVHPGVDLDVFTPG TH_2622|M.thermoresistible__bu VGEQQVVDEADRLIVNTEHEAQQLVSMHQADPDRIDVVHPGVDLSTFTPG MMAR_0812|M.marinum_M VGEQQVVDEADRLIVNTDDEAKQLISIHRADPARIDVVHPGVDLEVFRPG MUL_4556|M.ulcerans_Agy99 VGEQQVVDEADRLIVNTDDEAKQLISIHHADPARIDVVHPGVDLEVFRPG Mb0496|M.bovis_AF2122/97 VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG Rv0486|M.tuberculosis_H37Rv VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG MLBr_02443|M.leprae_Br4923 VGEQQVVDEADRMIVNTDDEARQLISIHRADPAKIDVAHPGVDLDMFRPG MAV_4664|M.avium_104 VGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPG MAB_4057c|M.abscessus_ATCC_199 VGEQQVVDEADRLIVNTKDEADQLVSIHNADPARIDIVHPGVDLDVFTPG :******* ***:****. ** *::*:* ** :**:.****** * ** Mflv_0086|M.gilvum_PYR-GCK DRAAARAALGLDPAARIVAFVGRIQPLKAPDVLLRAAALLPD----VHVV Mvan_0827|M.vanbaalenii_PYR-1 DRLAARAALGLDANSRIVAFVGRIQPLKAPDVLLRAAALLPD----VQVL MSMEG_0933|M.smegmatis_MC2_155 SRDAARAVFGLPTDQKIVAFVGRIQPLKAPDILLRAAAKLPG----VRVL TH_2622|M.thermoresistible__bu DRQAARRALGLSDDEQVVAFVGRIQPLKAPDILLRAAVRLTDSHPRLRIV MMAR_0812|M.marinum_M DRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRII MUL_4556|M.ulcerans_Agy99 DRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRII Mb0496|M.bovis_AF2122/97 DRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPG----VRII Rv0486|M.tuberculosis_H37Rv DRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPG----VRII MLBr_02443|M.leprae_Br4923 DRRAARAALGLPLDGNVVAFVGRIQPLKAPDIVLRAAAKLPQ----VRIV MAV_4664|M.avium_104 DRRAARAALGLPLDEDIVAFVGRIQPLKAPDIVLRAAAKLPG----VRIV MAB_4057c|M.abscessus_ATCC_199 DKAAARAEFGLRADEQVVAFVGRIQPLKAPDLLVRAAERLPG----VRVL .: ** :** :**************:::**. *. :::: Mflv_0086|M.gilvum_PYR-GCK IAGGPSGS---------GMATPDNLVHLAGELGIAERVTFLPPQSRDHLV Mvan_0827|M.vanbaalenii_PYR-1 IAGGPSGSGLISRPGAGGLATPDNLVNLAAELGMTDRVTFLPPQSRDNLV MSMEG_0933|M.smegmatis_MC2_155 IAGGPSGS---------GLAQPDTLVRLADELGISDRVTFLPPQSREQLV TH_2622|M.thermoresistible__bu VAGGPSGS---------GLGAPDSLIRLAEELDIGAHVTFLPPQSRDELV MMAR_0812|M.marinum_M VAGGPSGS---------GLASPDGLAQLADELGIAERVTFLPPQSRTDLA MUL_4556|M.ulcerans_Agy99 VAGGPSGS---------GLASPDGLAQLADELGIAERVTFLPPQSRTDLA Mb0496|M.bovis_AF2122/97 VAGGPSGS---------GLASPDGLVRLADELGISARVTFLPPQSHTDLA Rv0486|M.tuberculosis_H37Rv VAGGPSGS---------GLASPDGLVRLADELGISARVTFLPPQSHTDLA MLBr_02443|M.leprae_Br4923 VAGGPSGS---------GLASPDGLVRLADELGITARVTFLPPQSRTNLA MAV_4664|M.avium_104 VAGGPSGT---------GLASPDGLALLADELGISARVTFLPPQSRPNLA MAB_4057c|M.abscessus_ATCC_199 IVGGPSGS---------GLDEPTALQDLAVDLGIADRVTFLPPQTRERLA :.*****: *: * * ** :*.: :*******:: *. Mflv_0086|M.gilvum_PYR-GCK RVYRAADIVAVPSHNESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG Mvan_0827|M.vanbaalenii_PYR-1 QVYRAADVVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG MSMEG_0933|M.smegmatis_MC2_155 NVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVADGVSG TH_2622|M.thermoresistible__bu NVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTG MMAR_0812|M.marinum_M RVFHAVDLVAIPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG MUL_4556|M.ulcerans_Agy99 RVFHAVDLVAIPSYSESFGLVAVEAQACGTRVVAAAVGGLPVAVRDGVSG Mb0496|M.bovis_AF2122/97 TLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITG Rv0486|M.tuberculosis_H37Rv TLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITG MLBr_02443|M.leprae_Br4923 TVFQAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTG MAV_4664|M.avium_104 TLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRDGVTG MAB_4057c|M.abscessus_ATCC_199 QVYRAADIVAVPSYSESFGLVAIEAQACGTPVVAAAVGGLPVAVADQRTG :::*.::**:**:.*******:******* *.*********** * :* Mflv_0086|M.gilvum_PYR-GCK ALVHSHEPDAWATTLGEVFAADP----STFGRAAVDHAATFSWAHTVDAL Mvan_0827|M.vanbaalenii_PYR-1 ALVDGHDPGDWAGTLADVLAADP----ATLSRAAVDHAATFSWSHTVDAL MSMEG_0933|M.smegmatis_MC2_155 ALVDGHDIGDWADTISEVLDREP----AALSRASAEHAAQFSWAHTVDAL TH_2622|M.thermoresistible__bu QLVDGHDVGDWAETIGGLLDRDT----TAMRRAAIAHAGTFSWSNTVDAL MMAR_0812|M.marinum_M TLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDAL MUL_4556|M.ulcerans_Agy99 TLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDAL Mb0496|M.bovis_AF2122/97 TLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDAL Rv0486|M.tuberculosis_H37Rv TLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDAL MLBr_02443|M.leprae_Br4923 TLVFGHNVGHWADAVDQLLRLSAGPQARAISRAAVVHAAQFSWDNTTDAL MAV_4664|M.avium_104 TLVAGHDVDHWADALAGLLRAPA-PAAAAMSRAAAAHAATFSWDHTTDAL MAB_4057c|M.abscessus_ATCC_199 LLVPTHRTEDWADAIGELLVRKG----AGFSRAAVEHAAGFSWSSTADSL ** * ** :: :: : **: **. *** *.*:* Mflv_0086|M.gilvum_PYR-GCK LTGYGRAIADHRADNTL-------QVAARRSGRRFSMRRGVRA-- Mvan_0827|M.vanbaalenii_PYR-1 LAGYGRAIADHRARHQG-------QLARR-SGRRFSMRRGVRA-- MSMEG_0933|M.smegmatis_MC2_155 LASYSRAMSDYRARHPR-------PAARR-SGRRFSMRRGVRT-- TH_2622|M.thermoresistible__bu LASYGRAIADYRAAHRRP------EPSVRRNGRRFTMRRGVRA-- MMAR_0812|M.marinum_M LASYRRAIGDFTAGRRRK----VRDPVAARKPRRWTARRGVGA-- MUL_4556|M.ulcerans_Agy99 LASYRRAIGDFTAGRRRK----VRDPVAARKPRRWTARRGVGA-- Mb0496|M.bovis_AF2122/97 LASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA-- Rv0486|M.tuberculosis_H37Rv LASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA-- MLBr_02443|M.leprae_Br4923 LASYRRAIGDFTATRQHR----VRDLVATRKPRRWISRRGMGA-- MAV_4664|M.avium_104 LASYRRAIREYTTE-----------------------RRGVGA-- MAB_4057c|M.abscessus_ATCC_199 LSSYGRAIADYRAPQRPS--------TQWASRARFRPRRLSGLRR *:.* **: :. : **