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VRLATEPASLPSGLPEPRRVAVLSVHTSPLAQPGTGDAGGMNVYVLQTALELANRGVDVEIFTRATSSAD QPVVPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDIVHSHYWLSGQVGWLAAD RWAVPLVHTAHTLAAVKNASLAAGDAPEPPMRSIGEQQVVDAADRLIVNTEHEAQQLVSLHQADPARIDV VHPGVDLATFTPGDRLAARAALGLDANSRIVAFVGRIQPLKAPDVLLRAAALLPDVQVLIAGGPSGSGLI SRPGAGGLATPDNLVNLAAELGMTDRVTFLPPQSRDNLVQVYRAADVVAVPSYSESFGLVAVEAQACGTP VVAAAVGGLPVAVRDGVSGALVDGHDPGDWAGTLADVLAADPATLSRAAVDHAATFSWSHTVDALLAGYG RAIADHRARHQGQLARRSGRRFSMRRGVRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0827 | - | - | 100% (450) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_4504 | - | 7e-27 | 33.12% (320) | glycogen synthase |
| M. vanbaalenii PYR-1 | Mvan_2096 | - | 1e-22 | 28.83% (392) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0496 | - | 1e-180 | 71.62% (451) | mannosyltransferase |
| M. gilvum PYR-GCK | Mflv_0086 | - | 0.0 | 86.03% (451) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv0486 | - | 1e-180 | 71.62% (451) | mannosyltransferase |
| M. leprae Br4923 | MLBr_02443 | - | 1e-177 | 73.23% (437) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4057c | - | 1e-175 | 71.93% (431) | glycosyl transferase |
| M. marinum M | MMAR_0812 | - | 1e-180 | 72.79% (441) | mannosyltransferase |
| M. avium 104 | MAV_4664 | - | 1e-179 | 74.88% (422) | hypothetical protein MAV_4664 |
| M. smegmatis MC2 155 | MSMEG_0933 | - | 0.0 | 81.29% (449) | hypothetical protein MSMEG_0933 |
| M. thermoresistible (build 8) | TH_2622 | - | 0.0 | 77.19% (456) | PUTATIVE glycosyl transferase, group 1 |
| M. ulcerans Agy99 | MUL_4556 | - | 1e-179 | 72.56% (441) | mannosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0827|M.vanbaalenii_PYR-1 ---------------------------MRLATEPASLPSGLPEPRRVAVL
Mflv_0086|M.gilvum_PYR-GCK ---------------------------MRLATDPAGSSSGLPQPRRVAVL
MSMEG_0933|M.smegmatis_MC2_155 ---------------------------MRLATD-------LETPRRVAVL
TH_2622|M.thermoresistible__bu ---------------------------VRLTTAG---PLDPPIPQRVAVL
Mb0496|M.bovis_AF2122/97 MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL
Rv0486|M.tuberculosis_H37Rv MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALL
MLBr_02443|M.leprae_Br4923 ------------------------------------------------ML
MMAR_0812|M.marinum_M MRPMRAGAG----------AAGESCKDDGVRPDDVSRLTADAVVRRVALL
MUL_4556|M.ulcerans_Agy99 ---MRAGAG----------AAGESCKDDGVRPDDVSRLTADAVVRRVALL
MAV_4664|M.avium_104 -----------------------------MRHDDVFRLNE---PRRVAVL
MAB_4057c|M.abscessus_ATCC_199 ---------------------------MLSGDEFARRAVAALKPRRIAVL
:*
Mvan_0827|M.vanbaalenii_PYR-1 SVHTSPLAQPGTGDAGGMNVYVLQTALELANRGVDVEIFTRATSSADQPV
Mflv_0086|M.gilvum_PYR-GCK SVHTSPLAQPGTGDAGGMNVYVLQTSLELARRGVEVEIFTRATSSADQPI
MSMEG_0933|M.smegmatis_MC2_155 SVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVEVEVFTRATSSADAPV
TH_2622|M.thermoresistible__bu SVHTSPLHQPGTGDAGGLNVYVLQSALELARRGVEVEIFTRATSSADRPV
Mb0496|M.bovis_AF2122/97 AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV
Rv0486|M.tuberculosis_H37Rv AVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPV
MLBr_02443|M.leprae_Br4923 AVHTSPLAQPGIGDAGGMNVYVLQSALHLARRGIEVEIFTRATASADPPI
MMAR_0812|M.marinum_M AVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPV
MUL_4556|M.ulcerans_Agy99 AVHTSPLAQPGTGDAGGMNVYVLQSALHLAKRGIEVEIFTRATASADPPV
MAV_4664|M.avium_104 AVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATASADPPV
MAB_4057c|M.abscessus_ATCC_199 SVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVAVDIFTRATSSSDEPV
:****** *** *****:***:**::*.**.**: *::*****:*:* *:
Mvan_0827|M.vanbaalenii_PYR-1 VPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDI
Mflv_0086|M.gilvum_PYR-GCK VSVAPGVVVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDI
MSMEG_0933|M.smegmatis_MC2_155 VPVAPGVLVRNVVAGPFEGLDKNDLPTQLCAFTAGVLRAEATHEPGYYDV
TH_2622|M.thermoresistible__bu VPVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFTAGVLRAEATHEPGYYDI
Mb0496|M.bovis_AF2122/97 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI
Rv0486|M.tuberculosis_H37Rv VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDI
MLBr_02443|M.leprae_Br4923 VWVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGYYDI
MMAR_0812|M.marinum_M VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDI
MUL_4556|M.ulcerans_Agy99 VRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAAHEPGHYDI
MAV_4664|M.avium_104 QRVVPGVVVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDI
MAB_4057c|M.abscessus_ATCC_199 VSVTDGVTVRNIVAGPFEGLDKYDLPTQLCAFTAGVLRAEAVHEPGYYNL
*. ** ***:********** *********:******** ****:*::
Mvan_0827|M.vanbaalenii_PYR-1 VHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDAPEPPMRS
Mflv_0086|M.gilvum_PYR-GCK LHSHYWLSGQVGWLAADRWAVPLVHTAHTLAAVKNASLAAGDTPEPPMRA
MSMEG_0933|M.smegmatis_MC2_155 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAAGDAPEPPLRA
TH_2622|M.thermoresistible__bu VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAEGDSPEPPLRV
Mb0496|M.bovis_AF2122/97 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT
Rv0486|M.tuberculosis_H37Rv VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRT
MLBr_02443|M.leprae_Br4923 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDAAEPPLRS
MMAR_0812|M.marinum_M VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRT
MUL_4556|M.ulcerans_Agy99 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALANGDAPEPPLRT
MAV_4664|M.avium_104 VHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAQGDSPEPPLRT
MAB_4057c|M.abscessus_ATCC_199 VHSHYWLSGQAGWLARDRWGVPLVHTAHTLAAVKNQTLAEGDRPEPALRG
:*********.**** ***.*************** :** ** .**.:*
Mvan_0827|M.vanbaalenii_PYR-1 IGEQQVVDAADRLIVNTEHEAQQLVSLHQADPARIDVVHPGVDLATFTPG
Mflv_0086|M.gilvum_PYR-GCK IGEQQVVDEADRLIVNTEHEAQQLVSLHHADPGRIDVVHPGVDLATFTPG
MSMEG_0933|M.smegmatis_MC2_155 VGEQQVVDEADRLIVNTEVEAQQLVSLHNADRSRIDVVHPGVDLDVFTPG
TH_2622|M.thermoresistible__bu VGEQQVVDEADRLIVNTEHEAQQLVSMHQADPDRIDVVHPGVDLSTFTPG
Mb0496|M.bovis_AF2122/97 VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG
Rv0486|M.tuberculosis_H37Rv VGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPG
MLBr_02443|M.leprae_Br4923 VGEQQVVDEADRMIVNTDDEARQLISIHRADPAKIDVAHPGVDLDMFRPG
MMAR_0812|M.marinum_M VGEQQVVDEADRLIVNTDDEAKQLISIHRADPARIDVVHPGVDLEVFRPG
MUL_4556|M.ulcerans_Agy99 VGEQQVVDEADRLIVNTDDEAKQLISIHHADPARIDVVHPGVDLEVFRPG
MAV_4664|M.avium_104 VGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPG
MAB_4057c|M.abscessus_ATCC_199 VGEQQVVDEADRLIVNTKDEADQLVSIHNADPARIDIVHPGVDLDVFTPG
:******* ***:****. ** *::*:* ** :**:.****** * **
Mvan_0827|M.vanbaalenii_PYR-1 DRLAARAALGLDANSRIVAFVGRIQPLKAPDVLLRAAALLPD----VQVL
Mflv_0086|M.gilvum_PYR-GCK DRAAARAALGLDPAARIVAFVGRIQPLKAPDVLLRAAALLPD----VHVV
MSMEG_0933|M.smegmatis_MC2_155 SRDAARAVFGLPTDQKIVAFVGRIQPLKAPDILLRAAAKLPG----VRVL
TH_2622|M.thermoresistible__bu DRQAARRALGLSDDEQVVAFVGRIQPLKAPDILLRAAVRLTDSHPRLRIV
Mb0496|M.bovis_AF2122/97 DRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPG----VRII
Rv0486|M.tuberculosis_H37Rv DRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPG----VRII
MLBr_02443|M.leprae_Br4923 DRRAARAALGLPLDGNVVAFVGRIQPLKAPDIVLRAAAKLPQ----VRIV
MMAR_0812|M.marinum_M DRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRII
MUL_4556|M.ulcerans_Agy99 DRQQARTALGLRPEEKVVAFVGRIQPLKAPDIVLRAVAKLPG----VRII
MAV_4664|M.avium_104 DRRAARAALGLPLDEDIVAFVGRIQPLKAPDIVLRAAAKLPG----VRIV
MAB_4057c|M.abscessus_ATCC_199 DKAAARAEFGLRADEQVVAFVGRIQPLKAPDLLVRAAERLPG----VRVL
.: ** :** :**************:::**. *. ::::
Mvan_0827|M.vanbaalenii_PYR-1 IAGGPSGSGLISRPGAGGLATPDNLVNLAAELGMTDRVTFLPPQSRDNLV
Mflv_0086|M.gilvum_PYR-GCK IAGGPSGS---------GMATPDNLVHLAGELGIAERVTFLPPQSRDHLV
MSMEG_0933|M.smegmatis_MC2_155 IAGGPSGS---------GLAQPDTLVRLADELGISDRVTFLPPQSREQLV
TH_2622|M.thermoresistible__bu VAGGPSGS---------GLGAPDSLIRLAEELDIGAHVTFLPPQSRDELV
Mb0496|M.bovis_AF2122/97 VAGGPSGS---------GLASPDGLVRLADELGISARVTFLPPQSHTDLA
Rv0486|M.tuberculosis_H37Rv VAGGPSGS---------GLASPDGLVRLADELGISARVTFLPPQSHTDLA
MLBr_02443|M.leprae_Br4923 VAGGPSGS---------GLASPDGLVRLADELGITARVTFLPPQSRTNLA
MMAR_0812|M.marinum_M VAGGPSGS---------GLASPDGLAQLADELGIAERVTFLPPQSRTDLA
MUL_4556|M.ulcerans_Agy99 VAGGPSGS---------GLASPDGLAQLADELGIAERVTFLPPQSRTDLA
MAV_4664|M.avium_104 VAGGPSGT---------GLASPDGLALLADELGISARVTFLPPQSRPNLA
MAB_4057c|M.abscessus_ATCC_199 IVGGPSGS---------GLDEPTALQDLAVDLGIADRVTFLPPQTRERLA
:.*****: *: * * ** :*.: :*******:: *.
Mvan_0827|M.vanbaalenii_PYR-1 QVYRAADVVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG
Mflv_0086|M.gilvum_PYR-GCK RVYRAADIVAVPSHNESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG
MSMEG_0933|M.smegmatis_MC2_155 NVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVADGVSG
TH_2622|M.thermoresistible__bu NVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTG
Mb0496|M.bovis_AF2122/97 TLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITG
Rv0486|M.tuberculosis_H37Rv TLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITG
MLBr_02443|M.leprae_Br4923 TVFQAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTG
MMAR_0812|M.marinum_M RVFHAVDLVAIPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVSG
MUL_4556|M.ulcerans_Agy99 RVFHAVDLVAIPSYSESFGLVAVEAQACGTRVVAAAVGGLPVAVRDGVSG
MAV_4664|M.avium_104 TLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRDGVTG
MAB_4057c|M.abscessus_ATCC_199 QVYRAADIVAVPSYSESFGLVAIEAQACGTPVVAAAVGGLPVAVADQRTG
:::*.::**:**:.*******:******* *.*********** * :*
Mvan_0827|M.vanbaalenii_PYR-1 ALVDGHDPGDWAGTLADVLAADP----ATLSRAAVDHAATFSWSHTVDAL
Mflv_0086|M.gilvum_PYR-GCK ALVHSHEPDAWATTLGEVFAADP----STFGRAAVDHAATFSWAHTVDAL
MSMEG_0933|M.smegmatis_MC2_155 ALVDGHDIGDWADTISEVLDREP----AALSRASAEHAAQFSWAHTVDAL
TH_2622|M.thermoresistible__bu QLVDGHDVGDWAETIGGLLDRDT----TAMRRAAIAHAGTFSWSNTVDAL
Mb0496|M.bovis_AF2122/97 TLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDAL
Rv0486|M.tuberculosis_H37Rv TLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDAL
MLBr_02443|M.leprae_Br4923 TLVFGHNVGHWADAVDQLLRLSAGPQARAISRAAVVHAAQFSWDNTTDAL
MMAR_0812|M.marinum_M TLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDAL
MUL_4556|M.ulcerans_Agy99 TLVSGHDVDQWAAAIDGLLRSNAGAQGALMSRAAAEHAATFSWENTTDAL
MAV_4664|M.avium_104 TLVAGHDVDHWADALAGLLRAPA-PAAAAMSRAAAAHAATFSWDHTTDAL
MAB_4057c|M.abscessus_ATCC_199 LLVPTHRTEDWADAIGELLVRKG----AGFSRAAVEHAAGFSWSSTADSL
** * ** :: :: : **: **. *** *.*:*
Mvan_0827|M.vanbaalenii_PYR-1 LAGYGRAIADHRARHQG-------QLARR-SGRRFSMRRGVRA--
Mflv_0086|M.gilvum_PYR-GCK LTGYGRAIADHRADNTL-------QVAARRSGRRFSMRRGVRA--
MSMEG_0933|M.smegmatis_MC2_155 LASYSRAMSDYRARHPR-------PAARR-SGRRFSMRRGVRT--
TH_2622|M.thermoresistible__bu LASYGRAIADYRAAHRRP------EPSVRRNGRRFTMRRGVRA--
Mb0496|M.bovis_AF2122/97 LASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA--
Rv0486|M.tuberculosis_H37Rv LASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA--
MLBr_02443|M.leprae_Br4923 LASYRRAIGDFTATRQHR----VRDLVATRKPRRWISRRGMGA--
MMAR_0812|M.marinum_M LASYRRAIGDFTAGRRRK----VRDPVAARKPRRWTARRGVGA--
MUL_4556|M.ulcerans_Agy99 LASYRRAIGDFTAGRRRK----VRDPVAARKPRRWTARRGVGA--
MAV_4664|M.avium_104 LASYRRAIREYTTE-----------------------RRGVGA--
MAB_4057c|M.abscessus_ATCC_199 LSSYGRAIADYRAPQRPS--------TQWASRARFRPRRLSGLRR
*:.* **: :. : **