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GETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDVLYTSLLRRAITTAHLA LDAADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRY ADIGGGPLTECLADVVVRFLPYFTDVIVPDLRSGKTVLIVAHGNSLRALVKHLDQMSDDDVVGLNIPTGI PLRYDLDARLRPLVPGGTYLDPEAAAAGAAAVASQGGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4662 | gpmA | - | 100% (249) | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase |
| M. avium 104 | MAV_1752 | - | 2e-12 | 29.47% (190) | phosphoglycerate mutase family protein |
| M. avium 104 | MAV_4162 | - | 6e-11 | 39.78% (93) | acid phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0499 | gpmA | 1e-131 | 90.36% (249) | phosphoglyceromutase |
| M. gilvum PYR-GCK | Mflv_0084 | - | 1e-119 | 82.66% (248) | phosphoglycerate mutase 1 family protein |
| M. tuberculosis H37Rv | Rv0489 | gpmA | 1e-131 | 90.36% (249) | phosphoglyceromutase |
| M. leprae Br4923 | MLBr_02441 | gpmA | 1e-126 | 90.30% (237) | phosphoglyceromutase |
| M. abscessus ATCC 19977 | MAB_4049c | - | 1e-120 | 82.30% (243) | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase |
| M. marinum M | MMAR_0814 | gpmA | 1e-130 | 90.69% (247) | phosphoglycerate mutase 1 Gpm1 |
| M. smegmatis MC2 155 | MSMEG_0935 | - | 1e-120 | 83.95% (243) | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase |
| M. thermoresistible (build 8) | TH_0879 | gpm | 1e-112 | 80.83% (240) | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 |
| M. ulcerans Agy99 | MUL_4558 | gpmA | 1e-131 | 91.09% (247) | phosphoglycerate mutase 1 Gpm1 |
| M. vanbaalenii PYR-1 | Mvan_0829 | - | 1e-120 | 83.87% (248) | phosphoglycerate mutase 1 family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0499|M.bovis_AF2122/97 -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG
Rv0489|M.tuberculosis_H37Rv -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG
MMAR_0814|M.marinum_M -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG
MUL_4558|M.ulcerans_Agy99 -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG
MAV_4662|M.avium_104 -------MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSG
MLBr_02441|M.leprae_Br4923 -----MQQGNTATLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSG
Mflv_0084|M.gilvum_PYR-GCK -------MADTATLILLRHGESEWNALNLFTGWVDVDLTDKGRAEATRAG
Mvan_0829|M.vanbaalenii_PYR-1 -------MAETATLILLRHGESEWNALNLFTGWVDVDLTEKGRAEAARAG
MAB_4049c|M.abscessus_ATCC_199 MSGETSSKTNGATLILLRHGESQWNAKNLFTGWVDVDLTEKGRSEAQRGG
MSMEG_0935|M.smegmatis_MC2_155 ----------MATLILLRHGESQWNEKNLFTGWVDVDLTDKGRAEAVRGG
TH_0879|M.thermoresistible__bu MG-------NGATLILLRHGESDWNAKNLFTGWVDVDLTDKGRAEAVRAG
.:*:*******:** *********.**:**::** *.*
Mb0499|M.bovis_AF2122/97 ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
Rv0489|M.tuberculosis_H37Rv ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MMAR_0814|M.marinum_M ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MUL_4558|M.ulcerans_Agy99 ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MAV_4662|M.avium_104 ELLAEQGLLPDVLYTSLLRRAITTAHLALDAADRLWIPVRRSWRLNERHY
MLBr_02441|M.leprae_Br4923 ELLAEHNLLPDVLYTSLLRRAITTAHLALDTADWLWIPVRRSWRLNERHY
Mflv_0084|M.gilvum_PYR-GCK ELIGEQDKLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY
Mvan_0829|M.vanbaalenii_PYR-1 ELLKAQDRLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY
MAB_4049c|M.abscessus_ATCC_199 ELLAQQGLLPDILFTSLLRRAINTAHLALDTADRLWIPVVRDWRLNERHY
MSMEG_0935|M.smegmatis_MC2_155 QLMAEQGVLPDVLYTSLLRRAITTAHLALDAADRLWIPVHRDWRLNERHY
TH_0879|M.thermoresistible__bu ELMAELDRLPDVVYTSLLRRAITTANLALDRADRHWIPVHRSWRLNERHY
:*: . ***:::********.**::*** ** **** *.********
Mb0499|M.bovis_AF2122/97 GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD
Rv0489|M.tuberculosis_H37Rv GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD
MMAR_0814|M.marinum_M GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN
MUL_4558|M.ulcerans_Agy99 GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN
MAV_4662|M.avium_104 GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYAD
MLBr_02441|M.leprae_Br4923 GALQGLDKAVTKARYGEERFMAWRRSYDTPPPPIEKGSEFSQDADPRYTD
Mflv_0084|M.gilvum_PYR-GCK GALQGLNKAETKAKYGDEQFMAWRRSYDTPPPQIEAGSEFSQDRDPRYAD
Mvan_0829|M.vanbaalenii_PYR-1 GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIEAGSEFSQDRDPRYAD
MAB_4049c|M.abscessus_ATCC_199 GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIERGSHYSQDQDPRYAD
MSMEG_0935|M.smegmatis_MC2_155 GALQGLDKAETKEKYGEEQFMAWRRSYDTPPPPIEKGSKYSQDADPRYAD
TH_0879|M.thermoresistible__bu GALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIERGSTYSQDGDPRYAD
******:** ** :**:*:************* ** ** :*** ****::
Mb0499|M.bovis_AF2122/97 IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK
Rv0489|M.tuberculosis_H37Rv IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK
MMAR_0814|M.marinum_M IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK
MUL_4558|M.ulcerans_Agy99 IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK
MAV_4662|M.avium_104 IGGG-PLTECLADVVVRFLPYFTDVIVPDLRSGKTVLIVAHGNSLRALVK
MLBr_02441|M.leprae_Br4923 IGGG-PLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGNSLRALVK
Mflv_0084|M.gilvum_PYR-GCK IDGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK
Mvan_0829|M.vanbaalenii_PYR-1 VVGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK
MAB_4049c|M.abscessus_ATCC_199 IDGG-PLTECLADVVARFVPYYEEAIVPELRAGKTVLVAAHGNSLRALVK
MSMEG_0935|M.smegmatis_MC2_155 IDGG-PLTECLKDVVERFVPYYESAILPDLKAGKTVLIAAHGNSLRALVK
TH_0879|M.thermoresistible__bu IDGG-PLTECLADVVARFVPYYEQTIVPDLRAGKTVLIAAHGNSLRALVK
: ** ****** *** **:**: ..*: :*: *:***:.***********
Mb0499|M.bovis_AF2122/97 HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA
Rv0489|M.tuberculosis_H37Rv HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA
MMAR_0814|M.marinum_M HLDHMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA
MUL_4558|M.ulcerans_Agy99 HLDQMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA
MAV_4662|M.avium_104 HLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGAAA
MLBr_02441|M.leprae_Br4923 HLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPGGTYLDPEAAAA----
Mflv_0084|M.gilvum_PYR-GCK YLDGMSDDDVVGLNIPTGIPLRYDLDESLKPLVAGGSYLDPDAAAAGAAA
Mvan_0829|M.vanbaalenii_PYR-1 YLDGMSDEDVVGLNIPTGIPLRYDLDADLKPTVPGGSYLDPEAAAAGAAA
MAB_4049c|M.abscessus_ATCC_199 YLDGISDEEIVGLNIPTGIPLRYDLDENLKPVTPGGVYLDPEAAAAGAAA
MSMEG_0935|M.smegmatis_MC2_155 YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPVKIGGEYLDPEAAAAGAAA
TH_0879|M.thermoresistible__bu YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPKVVGGQYLDXGPAWANSG-
:** :**:::****:*********** ::* ** *** .* *
Mb0499|M.bovis_AF2122/97 VAGQGRG--
Rv0489|M.tuberculosis_H37Rv VAGQGRG--
MMAR_0814|M.marinum_M VASQGAAKA
MUL_4558|M.ulcerans_Agy99 VASQGAAKA
MAV_4662|M.avium_104 VASQGGG--
MLBr_02441|M.leprae_Br4923 VISQARP--
Mflv_0084|M.gilvum_PYR-GCK VAAQGAK--
Mvan_0829|M.vanbaalenii_PYR-1 VAAQGAK--
MAB_4049c|M.abscessus_ATCC_199 VANQGAK--
MSMEG_0935|M.smegmatis_MC2_155 VAAQGAKK-
TH_0879|M.thermoresistible__bu ---------