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M. thermoresistible (build 8) TH_0879 (gpm)

annotation: PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)
coordinates: 1783246 - 1783971
length: 242

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0879 gpm - 100% (242) PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)
M. thermoresistible (build 8) TH_0787 - 8e-16 31.63% (196) PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)
M. thermoresistible (build 8) TH_0648 entD 1e-09 38.78% (98) POSSIBLE PHOSPHOGLYCERATE MUTASE GPM2 (PHOSPHOGLYCEROMUTASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0499 gpmA 1e-110 79.58% (240) phosphoglyceromutase
M. gilvum PYR-GCK Mflv_0084 - 1e-116 82.99% (241) phosphoglycerate mutase 1 family protein
M. tuberculosis H37Rv Rv0489 gpmA 1e-110 79.58% (240) phosphoglyceromutase
M. leprae Br4923 MLBr_02441 gpmA 1e-110 80.95% (231) phosphoglyceromutase
M. abscessus ATCC 19977 MAB_4049c - 1e-116 83.61% (238) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
M. marinum M MMAR_0814 gpmA 1e-111 80.42% (240) phosphoglycerate mutase 1 Gpm1
M. avium 104 MAV_4662 gpmA 1e-112 80.83% (240) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
M. smegmatis MC2 155 MSMEG_0935 - 1e-118 86.44% (236) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
M. ulcerans Agy99 MUL_4558 gpmA 1e-111 80.42% (240) phosphoglycerate mutase 1 Gpm1
M. vanbaalenii PYR-1 Mvan_0829 - 1e-114 82.16% (241) phosphoglycerate mutase 1 family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0499|M.bovis_AF2122/97            -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG
Rv0489|M.tuberculosis_H37Rv         -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG
MMAR_0814|M.marinum_M               -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG
MUL_4558|M.ulcerans_Agy99           -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG
MAV_4662|M.avium_104                -------MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSG
MLBr_02441|M.leprae_Br4923          -----MQQGNTATLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSG
MAB_4049c|M.abscessus_ATCC_199      MSGETSSKTNGATLILLRHGESQWNAKNLFTGWVDVDLTEKGRSEAQRGG
MSMEG_0935|M.smegmatis_MC2_155      ----------MATLILLRHGESQWNEKNLFTGWVDVDLTDKGRAEAVRGG
TH_0879|M.thermoresistible__bu      MG-------NGATLILLRHGESDWNAKNLFTGWVDVDLTDKGRAEAVRAG
Mflv_0084|M.gilvum_PYR-GCK          -------MADTATLILLRHGESEWNALNLFTGWVDVDLTDKGRAEATRAG
Mvan_0829|M.vanbaalenii_PYR-1       -------MAETATLILLRHGESEWNALNLFTGWVDVDLTEKGRAEAARAG
                                               .:*:*******:**  *********.**:**::** *.*

Mb0499|M.bovis_AF2122/97            ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
Rv0489|M.tuberculosis_H37Rv         ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MMAR_0814|M.marinum_M               ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MUL_4558|M.ulcerans_Agy99           ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MAV_4662|M.avium_104                ELLAEQGLLPDVLYTSLLRRAITTAHLALDAADRLWIPVRRSWRLNERHY
MLBr_02441|M.leprae_Br4923          ELLAEHNLLPDVLYTSLLRRAITTAHLALDTADWLWIPVRRSWRLNERHY
MAB_4049c|M.abscessus_ATCC_199      ELLAQQGLLPDILFTSLLRRAINTAHLALDTADRLWIPVVRDWRLNERHY
MSMEG_0935|M.smegmatis_MC2_155      QLMAEQGVLPDVLYTSLLRRAITTAHLALDAADRLWIPVHRDWRLNERHY
TH_0879|M.thermoresistible__bu      ELMAELDRLPDVVYTSLLRRAITTANLALDRADRHWIPVHRSWRLNERHY
Mflv_0084|M.gilvum_PYR-GCK          ELIGEQDKLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY
Mvan_0829|M.vanbaalenii_PYR-1       ELLKAQDRLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY
                                    :*:   . ***:::********.**::*** **  **** *.********

Mb0499|M.bovis_AF2122/97            GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD
Rv0489|M.tuberculosis_H37Rv         GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD
MMAR_0814|M.marinum_M               GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN
MUL_4558|M.ulcerans_Agy99           GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN
MAV_4662|M.avium_104                GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYAD
MLBr_02441|M.leprae_Br4923          GALQGLDKAVTKARYGEERFMAWRRSYDTPPPPIEKGSEFSQDADPRYTD
MAB_4049c|M.abscessus_ATCC_199      GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIERGSHYSQDQDPRYAD
MSMEG_0935|M.smegmatis_MC2_155      GALQGLDKAETKEKYGEEQFMAWRRSYDTPPPPIEKGSKYSQDADPRYAD
TH_0879|M.thermoresistible__bu      GALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIERGSTYSQDGDPRYAD
Mflv_0084|M.gilvum_PYR-GCK          GALQGLNKAETKAKYGDEQFMAWRRSYDTPPPQIEAGSEFSQDRDPRYAD
Mvan_0829|M.vanbaalenii_PYR-1       GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIEAGSEFSQDRDPRYAD
                                    ******:** ** :**:*:************* ** ** :*** ****::

Mb0499|M.bovis_AF2122/97            IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK
Rv0489|M.tuberculosis_H37Rv         IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK
MMAR_0814|M.marinum_M               IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK
MUL_4558|M.ulcerans_Agy99           IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK
MAV_4662|M.avium_104                IGGG-PLTECLADVVVRFLPYFTDVIVPDLRSGKTVLIVAHGNSLRALVK
MLBr_02441|M.leprae_Br4923          IGGG-PLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGNSLRALVK
MAB_4049c|M.abscessus_ATCC_199      IDGG-PLTECLADVVARFVPYYEEAIVPELRAGKTVLVAAHGNSLRALVK
MSMEG_0935|M.smegmatis_MC2_155      IDGG-PLTECLKDVVERFVPYYESAILPDLKAGKTVLIAAHGNSLRALVK
TH_0879|M.thermoresistible__bu      IDGG-PLTECLADVVARFVPYYEQTIVPDLRAGKTVLIAAHGNSLRALVK
Mflv_0084|M.gilvum_PYR-GCK          IDGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK
Mvan_0829|M.vanbaalenii_PYR-1       VVGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK
                                    : ** ****** *** **:**: ..*: :*: *:***:.***********

Mb0499|M.bovis_AF2122/97            HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA
Rv0489|M.tuberculosis_H37Rv         HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA
MMAR_0814|M.marinum_M               HLDHMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA
MUL_4558|M.ulcerans_Agy99           HLDQMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA
MAV_4662|M.avium_104                HLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGAAA
MLBr_02441|M.leprae_Br4923          HLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPGGTYLDPEAAAA----
MAB_4049c|M.abscessus_ATCC_199      YLDGISDEEIVGLNIPTGIPLRYDLDENLKPVTPGGVYLDPEAAAAGAAA
MSMEG_0935|M.smegmatis_MC2_155      YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPVKIGGEYLDPEAAAAGAAA
TH_0879|M.thermoresistible__bu      YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPKVVGGQYLDXGPAWANSG-
Mflv_0084|M.gilvum_PYR-GCK          YLDGMSDDDVVGLNIPTGIPLRYDLDESLKPLVAGGSYLDPDAAAAGAAA
Mvan_0829|M.vanbaalenii_PYR-1       YLDGMSDEDVVGLNIPTGIPLRYDLDADLKPTVPGGSYLDPEAAAAGAAA
                                    :** :**:::****:***********  ::*   ** ***  .* *    

Mb0499|M.bovis_AF2122/97            VAGQGRG--
Rv0489|M.tuberculosis_H37Rv         VAGQGRG--
MMAR_0814|M.marinum_M               VASQGAAKA
MUL_4558|M.ulcerans_Agy99           VASQGAAKA
MAV_4662|M.avium_104                VASQGGG--
MLBr_02441|M.leprae_Br4923          VISQARP--
MAB_4049c|M.abscessus_ATCC_199      VANQGAK--
MSMEG_0935|M.smegmatis_MC2_155      VAAQGAKK-
TH_0879|M.thermoresistible__bu      ---------
Mflv_0084|M.gilvum_PYR-GCK          VAAQGAK--
Mvan_0829|M.vanbaalenii_PYR-1       VAAQGAK--

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0879	gpm	-	100% (242)	PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)
M. thermoresistible (build 8)	TH_0787	-	8e-16	31.63% (196)	PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)
M. thermoresistible (build 8)	TH_0648	entD	1e-09	38.78% (98)	POSSIBLE PHOSPHOGLYCERATE MUTASE GPM2 (PHOSPHOGLYCEROMUTASE)