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MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSGELLAEQDLLPDVLYTSLLRRAITTAHL ALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPR YANIDGGPLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVKHLDQMSDEDIVGLNIPTG IPLRYDLDERLQPVVPGGTYLDPEAAAAGAAAVASQGAAKA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_4558 | gpmA | - | 100% (251) | phosphoglycerate mutase 1 Gpm1 |
M. ulcerans Agy99 | MUL_3691 | gpm_1 | 3e-14 | 32.11% (190) | phosphoglycerate mutase, Gpm_1 |
M. ulcerans Agy99 | MUL_2536 | gpm2 | 2e-09 | 33.64% (110) | acid phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0499 | gpmA | 1e-130 | 90.69% (247) | phosphoglyceromutase |
M. gilvum PYR-GCK | Mflv_0084 | - | 1e-119 | 82.33% (249) | phosphoglycerate mutase 1 family protein |
M. tuberculosis H37Rv | Rv0489 | gpmA | 1e-130 | 90.69% (247) | phosphoglyceromutase |
M. leprae Br4923 | MLBr_02441 | gpmA | 1e-124 | 89.03% (237) | phosphoglyceromutase |
M. abscessus ATCC 19977 | MAB_4049c | - | 1e-119 | 83.54% (243) | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase |
M. marinum M | MMAR_0814 | gpmA | 1e-144 | 99.60% (251) | phosphoglycerate mutase 1 Gpm1 |
M. avium 104 | MAV_4662 | gpmA | 1e-131 | 91.09% (247) | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase |
M. smegmatis MC2 155 | MSMEG_0935 | - | 1e-119 | 82.86% (245) | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase |
M. thermoresistible (build 8) | TH_0879 | gpm | 1e-111 | 80.42% (240) | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 |
M. vanbaalenii PYR-1 | Mvan_0829 | - | 1e-118 | 83.13% (249) | phosphoglycerate mutase 1 family protein |
CLUSTAL 2.0.9 multiple sequence alignment MUL_4558|M.ulcerans_Agy99 -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG MMAR_0814|M.marinum_M -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG Mb0499|M.bovis_AF2122/97 -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG Rv0489|M.tuberculosis_H37Rv -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG MAV_4662|M.avium_104 -------MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSG MLBr_02441|M.leprae_Br4923 -----MQQGNTATLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSG Mflv_0084|M.gilvum_PYR-GCK -------MADTATLILLRHGESEWNALNLFTGWVDVDLTDKGRAEATRAG Mvan_0829|M.vanbaalenii_PYR-1 -------MAETATLILLRHGESEWNALNLFTGWVDVDLTEKGRAEAARAG MAB_4049c|M.abscessus_ATCC_199 MSGETSSKTNGATLILLRHGESQWNAKNLFTGWVDVDLTEKGRSEAQRGG MSMEG_0935|M.smegmatis_MC2_155 ----------MATLILLRHGESQWNEKNLFTGWVDVDLTDKGRAEAVRGG TH_0879|M.thermoresistible__bu MG-------NGATLILLRHGESDWNAKNLFTGWVDVDLTDKGRAEAVRAG .:*:*******:** *********.**:**::** *.* MUL_4558|M.ulcerans_Agy99 ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY MMAR_0814|M.marinum_M ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY Mb0499|M.bovis_AF2122/97 ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY Rv0489|M.tuberculosis_H37Rv ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY MAV_4662|M.avium_104 ELLAEQGLLPDVLYTSLLRRAITTAHLALDAADRLWIPVRRSWRLNERHY MLBr_02441|M.leprae_Br4923 ELLAEHNLLPDVLYTSLLRRAITTAHLALDTADWLWIPVRRSWRLNERHY Mflv_0084|M.gilvum_PYR-GCK ELIGEQDKLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY Mvan_0829|M.vanbaalenii_PYR-1 ELLKAQDRLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY MAB_4049c|M.abscessus_ATCC_199 ELLAQQGLLPDILFTSLLRRAINTAHLALDTADRLWIPVVRDWRLNERHY MSMEG_0935|M.smegmatis_MC2_155 QLMAEQGVLPDVLYTSLLRRAITTAHLALDAADRLWIPVHRDWRLNERHY TH_0879|M.thermoresistible__bu ELMAELDRLPDVVYTSLLRRAITTANLALDRADRHWIPVHRSWRLNERHY :*: . ***:::********.**::*** ** **** *.******** MUL_4558|M.ulcerans_Agy99 GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN MMAR_0814|M.marinum_M GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN Mb0499|M.bovis_AF2122/97 GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD Rv0489|M.tuberculosis_H37Rv GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD MAV_4662|M.avium_104 GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYAD MLBr_02441|M.leprae_Br4923 GALQGLDKAVTKARYGEERFMAWRRSYDTPPPPIEKGSEFSQDADPRYTD Mflv_0084|M.gilvum_PYR-GCK GALQGLNKAETKAKYGDEQFMAWRRSYDTPPPQIEAGSEFSQDRDPRYAD Mvan_0829|M.vanbaalenii_PYR-1 GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIEAGSEFSQDRDPRYAD MAB_4049c|M.abscessus_ATCC_199 GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIERGSHYSQDQDPRYAD MSMEG_0935|M.smegmatis_MC2_155 GALQGLDKAETKEKYGEEQFMAWRRSYDTPPPPIEKGSKYSQDADPRYAD TH_0879|M.thermoresistible__bu GALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIERGSTYSQDGDPRYAD ******:** ** :**:*:************* ** ** :*** ****:: MUL_4558|M.ulcerans_Agy99 IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK MMAR_0814|M.marinum_M IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK Mb0499|M.bovis_AF2122/97 IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK Rv0489|M.tuberculosis_H37Rv IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK MAV_4662|M.avium_104 IGGG-PLTECLADVVVRFLPYFTDVIVPDLRSGKTVLIVAHGNSLRALVK MLBr_02441|M.leprae_Br4923 IGGG-PLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGNSLRALVK Mflv_0084|M.gilvum_PYR-GCK IDGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK Mvan_0829|M.vanbaalenii_PYR-1 VVGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK MAB_4049c|M.abscessus_ATCC_199 IDGG-PLTECLADVVARFVPYYEEAIVPELRAGKTVLVAAHGNSLRALVK MSMEG_0935|M.smegmatis_MC2_155 IDGG-PLTECLKDVVERFVPYYESAILPDLKAGKTVLIAAHGNSLRALVK TH_0879|M.thermoresistible__bu IDGG-PLTECLADVVARFVPYYEQTIVPDLRAGKTVLIAAHGNSLRALVK : ** ****** *** **:**: ..*: :*: *:***:.*********** MUL_4558|M.ulcerans_Agy99 HLDQMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA MMAR_0814|M.marinum_M HLDHMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA Mb0499|M.bovis_AF2122/97 HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA Rv0489|M.tuberculosis_H37Rv HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA MAV_4662|M.avium_104 HLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGAAA MLBr_02441|M.leprae_Br4923 HLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPGGTYLDPEAAAA---- Mflv_0084|M.gilvum_PYR-GCK YLDGMSDDDVVGLNIPTGIPLRYDLDESLKPLVAGGSYLDPDAAAAGAAA Mvan_0829|M.vanbaalenii_PYR-1 YLDGMSDEDVVGLNIPTGIPLRYDLDADLKPTVPGGSYLDPEAAAAGAAA MAB_4049c|M.abscessus_ATCC_199 YLDGISDEEIVGLNIPTGIPLRYDLDENLKPVTPGGVYLDPEAAAAGAAA MSMEG_0935|M.smegmatis_MC2_155 YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPVKIGGEYLDPEAAAAGAAA TH_0879|M.thermoresistible__bu YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPKVVGGQYLDXGPAWANSG- :** :**:::****:*********** ::* ** *** .* * MUL_4558|M.ulcerans_Agy99 VASQGAAKA MMAR_0814|M.marinum_M VASQGAAKA Mb0499|M.bovis_AF2122/97 VAGQGRG-- Rv0489|M.tuberculosis_H37Rv VAGQGRG-- MAV_4662|M.avium_104 VASQGGG-- MLBr_02441|M.leprae_Br4923 VISQARP-- Mflv_0084|M.gilvum_PYR-GCK VAAQGAK-- Mvan_0829|M.vanbaalenii_PYR-1 VAAQGAK-- MAB_4049c|M.abscessus_ATCC_199 VANQGAK-- MSMEG_0935|M.smegmatis_MC2_155 VAAQGAKK- TH_0879|M.thermoresistible__bu ---------