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M. ulcerans Agy99 MUL_4558 (gpmA)

annotation: phosphoglycerate mutase 1 Gpm1
coordinates: 5057717 - 5058472
length: 251

MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSGELLAEQDLLPDVLYTSLLRRAITTAHL
ALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPR
YANIDGGPLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVKHLDQMSDEDIVGLNIPTG
IPLRYDLDERLQPVVPGGTYLDPEAAAAGAAAVASQGAAKA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4558gpmA-100% (251)phosphoglycerate mutase 1 Gpm1
M. ulcerans Agy99MUL_3691gpm_13e-1432.11% (190) phosphoglycerate mutase, Gpm_1
M. ulcerans Agy99MUL_2536gpm22e-0933.64% (110) acid phosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0499gpmA1e-13090.69% (247) phosphoglyceromutase
M. gilvum PYR-GCKMflv_0084-1e-11982.33% (249) phosphoglycerate mutase 1 family protein
M. tuberculosis H37RvRv0489gpmA1e-13090.69% (247) phosphoglyceromutase
M. leprae Br4923MLBr_02441gpmA1e-12489.03% (237) phosphoglyceromutase
M. abscessus ATCC 19977MAB_4049c-1e-11983.54% (243) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
M. marinum MMMAR_0814gpmA1e-14499.60% (251) phosphoglycerate mutase 1 Gpm1
M. avium 104MAV_4662gpmA1e-13191.09% (247) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
M. smegmatis MC2 155MSMEG_0935-1e-11982.86% (245) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
M. thermoresistible (build 8)TH_0879gpm1e-11180.42% (240) PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1
M. vanbaalenii PYR-1Mvan_0829-1e-11883.13% (249) phosphoglycerate mutase 1 family protein

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4558|M.ulcerans_Agy99           -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG
MMAR_0814|M.marinum_M               -------MGDTGTLVLLRHGESDWNARNLFTGWVDVGLTEKGRAEAVRSG
Mb0499|M.bovis_AF2122/97            -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG
Rv0489|M.tuberculosis_H37Rv         -------MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSG
MAV_4662|M.avium_104                -------MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSG
MLBr_02441|M.leprae_Br4923          -----MQQGNTATLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSG
Mflv_0084|M.gilvum_PYR-GCK          -------MADTATLILLRHGESEWNALNLFTGWVDVDLTDKGRAEATRAG
Mvan_0829|M.vanbaalenii_PYR-1       -------MAETATLILLRHGESEWNALNLFTGWVDVDLTEKGRAEAARAG
MAB_4049c|M.abscessus_ATCC_199      MSGETSSKTNGATLILLRHGESQWNAKNLFTGWVDVDLTEKGRSEAQRGG
MSMEG_0935|M.smegmatis_MC2_155      ----------MATLILLRHGESQWNEKNLFTGWVDVDLTDKGRAEAVRGG
TH_0879|M.thermoresistible__bu      MG-------NGATLILLRHGESDWNAKNLFTGWVDVDLTDKGRAEAVRAG
                                               .:*:*******:**  *********.**:**::** *.*

MUL_4558|M.ulcerans_Agy99           ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MMAR_0814|M.marinum_M               ELLAEQDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
Mb0499|M.bovis_AF2122/97            ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
Rv0489|M.tuberculosis_H37Rv         ELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHY
MAV_4662|M.avium_104                ELLAEQGLLPDVLYTSLLRRAITTAHLALDAADRLWIPVRRSWRLNERHY
MLBr_02441|M.leprae_Br4923          ELLAEHNLLPDVLYTSLLRRAITTAHLALDTADWLWIPVRRSWRLNERHY
Mflv_0084|M.gilvum_PYR-GCK          ELIGEQDKLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY
Mvan_0829|M.vanbaalenii_PYR-1       ELLKAQDRLPDVLYTSLLRRAITTANIALDKADRHWIPVHRDWRLNERHY
MAB_4049c|M.abscessus_ATCC_199      ELLAQQGLLPDILFTSLLRRAINTAHLALDTADRLWIPVVRDWRLNERHY
MSMEG_0935|M.smegmatis_MC2_155      QLMAEQGVLPDVLYTSLLRRAITTAHLALDAADRLWIPVHRDWRLNERHY
TH_0879|M.thermoresistible__bu      ELMAELDRLPDVVYTSLLRRAITTANLALDRADRHWIPVHRSWRLNERHY
                                    :*:   . ***:::********.**::*** **  **** *.********

MUL_4558|M.ulcerans_Agy99           GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN
MMAR_0814|M.marinum_M               GALQGLDKAETKARYGEEQFMAWRRSYDTPPPLIEKGSEFSQDADPRYAN
Mb0499|M.bovis_AF2122/97            GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD
Rv0489|M.tuberculosis_H37Rv         GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYAD
MAV_4662|M.avium_104                GALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYAD
MLBr_02441|M.leprae_Br4923          GALQGLDKAVTKARYGEERFMAWRRSYDTPPPPIEKGSEFSQDADPRYTD
Mflv_0084|M.gilvum_PYR-GCK          GALQGLNKAETKAKYGDEQFMAWRRSYDTPPPQIEAGSEFSQDRDPRYAD
Mvan_0829|M.vanbaalenii_PYR-1       GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIEAGSEFSQDRDPRYAD
MAB_4049c|M.abscessus_ATCC_199      GALQGLDKAETKAKYGEEQFMAWRRSYDTPPPPIERGSHYSQDQDPRYAD
MSMEG_0935|M.smegmatis_MC2_155      GALQGLDKAETKEKYGEEQFMAWRRSYDTPPPPIEKGSKYSQDADPRYAD
TH_0879|M.thermoresistible__bu      GALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIERGSTYSQDGDPRYAD
                                    ******:** ** :**:*:************* ** ** :*** ****::

MUL_4558|M.ulcerans_Agy99           IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK
MMAR_0814|M.marinum_M               IDGG-PLTECLADVVARFLPYFTDVIVGDLRAGKTVLIVAHGNSLRALVK
Mb0499|M.bovis_AF2122/97            IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK
Rv0489|M.tuberculosis_H37Rv         IGGG-PLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVK
MAV_4662|M.avium_104                IGGG-PLTECLADVVVRFLPYFTDVIVPDLRSGKTVLIVAHGNSLRALVK
MLBr_02441|M.leprae_Br4923          IGGG-PLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGNSLRALVK
Mflv_0084|M.gilvum_PYR-GCK          IDGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK
Mvan_0829|M.vanbaalenii_PYR-1       VVGGAPLTECLKDVVERFVPYFTEVIVPDLKAGKTVLIAAHGNSLRALVK
MAB_4049c|M.abscessus_ATCC_199      IDGG-PLTECLADVVARFVPYYEEAIVPELRAGKTVLVAAHGNSLRALVK
MSMEG_0935|M.smegmatis_MC2_155      IDGG-PLTECLKDVVERFVPYYESAILPDLKAGKTVLIAAHGNSLRALVK
TH_0879|M.thermoresistible__bu      IDGG-PLTECLADVVARFVPYYEQTIVPDLRAGKTVLIAAHGNSLRALVK
                                    : ** ****** *** **:**: ..*: :*: *:***:.***********

MUL_4558|M.ulcerans_Agy99           HLDQMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA
MMAR_0814|M.marinum_M               HLDHMSDEDIVGLNIPTGIPLRYDLDERLQPVVPGGTYLDPEAAAAGAAA
Mb0499|M.bovis_AF2122/97            HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA
Rv0489|M.tuberculosis_H37Rv         HLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAA
MAV_4662|M.avium_104                HLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGAAA
MLBr_02441|M.leprae_Br4923          HLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPGGTYLDPEAAAA----
Mflv_0084|M.gilvum_PYR-GCK          YLDGMSDDDVVGLNIPTGIPLRYDLDESLKPLVAGGSYLDPDAAAAGAAA
Mvan_0829|M.vanbaalenii_PYR-1       YLDGMSDEDVVGLNIPTGIPLRYDLDADLKPTVPGGSYLDPEAAAAGAAA
MAB_4049c|M.abscessus_ATCC_199      YLDGISDEEIVGLNIPTGIPLRYDLDENLKPVTPGGVYLDPEAAAAGAAA
MSMEG_0935|M.smegmatis_MC2_155      YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPVKIGGEYLDPEAAAAGAAA
TH_0879|M.thermoresistible__bu      YLDGMSDEEVVGLNIPTGIPLRYDLDENLKPKVVGGQYLDXGPAWANSG-
                                    :** :**:::****:***********  ::*   ** ***  .* *    

MUL_4558|M.ulcerans_Agy99           VASQGAAKA
MMAR_0814|M.marinum_M               VASQGAAKA
Mb0499|M.bovis_AF2122/97            VAGQGRG--
Rv0489|M.tuberculosis_H37Rv         VAGQGRG--
MAV_4662|M.avium_104                VASQGGG--
MLBr_02441|M.leprae_Br4923          VISQARP--
Mflv_0084|M.gilvum_PYR-GCK          VAAQGAK--
Mvan_0829|M.vanbaalenii_PYR-1       VAAQGAK--
MAB_4049c|M.abscessus_ATCC_199      VANQGAK--
MSMEG_0935|M.smegmatis_MC2_155      VAAQGAKK-
TH_0879|M.thermoresistible__bu      ---------