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M. avium 104 MAV_4343 (-)

annotation: 3-oxoacyl-(acyl carrier protein) synthase II
coordinates: 4479517 - 4480776
length: 419

MTELVTGETLPNVVVTGIAMTTALATDADTTWKLLLDSQSGIRKLEDSFVEEFDLPVRIGGHLLEDFDDG
LTRAERHRMGYLQMMSTVLGRRVWENAGSPEVDSNRLMVSIGTGLGSAEQIVFSYDDLRARGMKGVSPLA
VSKYMPDGAAVAVGLERHAKAGVITPVSACASGSEGIAQAWRNIVFGEADIAICGGVEVRIEAVAIAAFA
QMRIVMSTKNDDPVGACRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHMVAP
DPNGERAGHAMSRAIQLAGLTPKDITHVNAHATGTSVGDVAEGKAINNALGPHGGNAAVYAPKAALGHSV
GAVGAVESILTVLALRDQVVPPTLNLENLDPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4343--100% (419)3-oxoacyl-(acyl carrier protein) synthase II
M. avium 104MAV_2191-0.092.84% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. avium 104MAV_2192-e-14963.81% (409) 3-oxoacyl-(acyl carrier protein) synthase II

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2270kasB0.084.96% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. gilvum PYR-GCKMflv_2776-0.079.95% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. tuberculosis H37RvRv2246kasB0.084.96% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. leprae Br4923MLBr_01656kasB0.082.25% (417) 3-oxoacyl-(acyl carrier protein) synthase II
M. abscessus ATCC 19977MAB_4608-1e-15765.45% (411) 3-oxoacyl-(acyl carrier protein) synthase II
M. marinum MMMAR_3339kasB0.083.53% (419) 3-oxoacyl-
M. smegmatis MC2 155MSMEG_4328-0.077.33% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. thermoresistible (build 8)TH_2837-0.081.08% (407) PUTATIVE beta-ketoacyl synthase
M. ulcerans Agy99MUL_1303kasB0.083.53% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. vanbaalenii PYR-1Mvan_3757-0.079.00% (419) 3-oxoacyl-(acyl carrier protein) synthase II

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2776|M.gilvum_PYR-GCK          ---------------------MASPTTGN-GLPDVVVTGIAMTTALATDA
Mvan_3757|M.vanbaalenii_PYR-1       ---------------------MASPTTGN-GLPDVVVTGIAMTTSLATDA
MMAR_3339|M.marinum_M               ---------------------MTELVTGK-AFPHVVVTGIAMTTALATDA
MUL_1303|M.ulcerans_Agy99           ---------------------MTELVTGK-AFPHVVVTGIAMTTALATDA
Mb2270|M.bovis_AF2122/97            MGVPPLAGASRTDMEGTFARPMTELVTGK-AFPYVVVTGIAMTTALATDA
Rv2246|M.tuberculosis_H37Rv         MGVPPLAGASRTDMEGTFARPMTELVTGK-AFPYVVVTGIAMTTALATDA
MLBr_01656|M.leprae_Br4923          -------------MIARLMTTSPELVTGK-AFPNVVVTGIAMTTALATDA
MAV_4343|M.avium_104                ---------------------MTELVTGE-TLPNVVVTGIAMTTALATDA
MSMEG_4328|M.smegmatis_MC2_155      ---------------------MAALSTGN-GLPNVVVTGVAMTTALATDA
TH_2837|M.thermoresistible__bu      ----------------------------------VVVTGVAMTTALATDA
MAB_4608|M.abscessus_ATCC_1997      ---------------------MAKPSTANGGFPNIVVTGMAMTTSIAPDV
                                                                      :****:****::*.*.

Mflv_2776|M.gilvum_PYR-GCK          EQTWTSLLDGRSGIRKLDDPFVEQFDLPVRIGGHL-LEEFDAQLTKVENR
Mvan_3757|M.vanbaalenii_PYR-1       EATWKSLLDGHSGIRKLQDPFVEEFDLPVQIGGHL-LEEFDSQLTKVENR
MMAR_3339|M.marinum_M               ETTWKLLLDSQSGIRTLDDPFVEEFNLPVRIGGHL-LEEFDHQLTRVELR
MUL_1303|M.ulcerans_Agy99           ETTWKLLLDSQSGIRTLDDPFVEEFNLPVRIGGHL-LEEFDHQLTRVELR
Mb2270|M.bovis_AF2122/97            ETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHL-LEEFDHQLTRIELR
Rv2246|M.tuberculosis_H37Rv         ETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHL-LEEFDHQLTRIELR
MLBr_01656|M.leprae_Br4923          ETTWKLLLDNQSGIRMLDDPFIEEFNLPVRIGGHL-LEEFDHQLTRVELR
MAV_4343|M.avium_104                DTTWKLLLDSQSGIRKLEDSFVEEFDLPVRIGGHL-LEDFDDGLTRAERH
MSMEG_4328|M.smegmatis_MC2_155      ESTWKKLLDGQSGIRTLTDPFVEEYNLPVRIGGHL-LEEFDSELTRVELR
TH_2837|M.thermoresistible__bu      EGTWKKLLDGQSGIRLLEDDFIEKYDLPVRIGGHL-LEDFDSELTRVELR
MAB_4608|M.abscessus_ATCC_1997      EGTWKGLLNGESGIRVLDDDFVAQYDLPVKIGGHLKVRDFDKDMTKIELR
                                    : **. **: .**** * * *: :::***:***** :.:**  :*: * :

Mflv_2776|M.gilvum_PYR-GCK          RMSYIQKMATVLGRRVWENAGAPE-VDTERLLVSIGTGLGGAEALVFAYD
Mvan_3757|M.vanbaalenii_PYR-1       RMSYVQKMATVLGRRVWENAGSPE-VDTERLLVSIGTGLGGAEALVFAYD
MMAR_3339|M.marinum_M               RTAYLQRMSTVIGRRVWENAGSPE-VDTNRLAVSIGTGLGSAEELVFGYD
MUL_1303|M.ulcerans_Agy99           RTAYLQRMSTVIGRRVWENAGSPE-VDTNRLAVSIGTGLGSAEELVFGYD
Mb2270|M.bovis_AF2122/97            RMGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYD
Rv2246|M.tuberculosis_H37Rv         RMGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYD
MLBr_01656|M.leprae_Br4923          RMGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYD
MAV_4343|M.avium_104                RMGYLQMMSTVLGRRVWENAGSPE-VDSNRLMVSIGTGLGSAEQIVFSYD
MSMEG_4328|M.smegmatis_MC2_155      RLSYLQKMATVLGRRVWANAGSPE-VDARRLMVSMGTGLGSTEELVFAYD
TH_2837|M.thermoresistible__bu      RLSYLQKMSTVLSRRVWENAGSPE-VDPRRLMVSIGTGMGSTEELVFSYD
MAB_4608|M.abscessus_ATCC_1997      RLSYVQRLAAILGRQVWEDAGAPEDIDLERLTVSVGTGLGGGEKLVEAYD
                                    * .*:* :::::.*::* :**:** :* .** **:***:*. * :* .**

Mflv_2776|M.gilvum_PYR-GCK          GLRERGLRSVSPLSVQMYMPNGPSAVVGLERHAKAGVVTPVSACASGSEG
Mvan_3757|M.vanbaalenii_PYR-1       GLRERGLRSVSPLSVQMYMPNGPSAVVGLERHAKAGVVTPVSACASGSEG
MMAR_3339|M.marinum_M               EMRVRGFRAISPLAVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGSEA
MUL_1303|M.ulcerans_Agy99           EMRVRGFRAISPLAVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGSEA
Mb2270|M.bovis_AF2122/97            DMRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEA
Rv2246|M.tuberculosis_H37Rv         DMRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEA
MLBr_01656|M.leprae_Br4923          DMRARGMKAVSPLAVQKYMPNGAAAAVGLEHHAKAGVMTPVSACASGSEA
MAV_4343|M.avium_104                DLRARGMKGVSPLAVSKYMPDGAAVAVGLERHAKAGVITPVSACASGSEG
MSMEG_4328|M.smegmatis_MC2_155      GMRSKGLRAVSPLVVQMYMPNGAAAAIGLERQAKAGVCTSISACASGSEA
TH_2837|M.thermoresistible__bu      DMRAKGLKAVSPLAVQKYMPNAAAAAVGLERKARAGVITPVSACASGSEG
MAB_4608|M.abscessus_ATCC_1997      EMRARGTKAVSPLTVQMFMPNGPAAVIGLERKARGGVITPVSACASGNEG
                                     :* :* :.:*** *. :**:..:..:***::*:.** *.:****** *.

Mflv_2776|M.gilvum_PYR-GCK          IAQAWRNIVMGEADIAICGGVEQRIEAVPIAAFAQMRIVMSTNNDDPAGA
Mvan_3757|M.vanbaalenii_PYR-1       IAQAWRNIVLGEADIAICGGVEQRIEAVPIAGFAQMRIVMSANNDDPAGA
MMAR_3339|M.marinum_M               IARAWQQVVLGEADIAICGGVETRIEAVPIAGFANMRIVMSTNNDDPAGA
MUL_1303|M.ulcerans_Agy99           IARAWQQVVLGEADIAICGGVETRIEAVPIAGFANMRIVMSTNNDDPAGA
Mb2270|M.bovis_AF2122/97            IARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGA
Rv2246|M.tuberculosis_H37Rv         IARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGA
MLBr_01656|M.leprae_Br4923          IAHAWQQIVLGEADSAICGGVETKIEAVPIAGFSQMRIVMSTKNDNPAGA
MAV_4343|M.avium_104                IAQAWRNIVFGEADIAICGGVEVRIEAVAIAAFAQMRIVMSTKNDDPVGA
MSMEG_4328|M.smegmatis_MC2_155      IANAWRNIVLGEADIAICGGVETKIEAVPIAGFAQMRIVLSNSNDDPEGA
TH_2837|M.thermoresistible__bu      IAHAWRNIVLGEADIAICGGVETKIEAVPIAGFAQMRIVLSTTNDDPPGA
MAB_4608|M.abscessus_ATCC_1997      IAHAWRQIAYGDADIAICGGIEAAIEAAPIAAFANMRIVMSTDNDNPAGA
                                    **.**:::. *:** *****:*  ***..**.*::****:*  **:* **

Mflv_2776|M.gilvum_PYR-GCK          CRPFDKDRDGFVFGEAGALLVIETEEHAKARGATPLARLMGASITSDGFH
Mvan_3757|M.vanbaalenii_PYR-1       CRPFDKDRDGFVFGEAGALMVIETEEHARARGATPLARVMGASITSDGYH
MMAR_3339|M.marinum_M               CRPFDKDRDGFVFGEGGALMVIETEEHAKARGANILARIMGASITSDGFH
MUL_1303|M.ulcerans_Agy99           CRPFDKDRDGFVFGEGGALMVIETEEHAKARGANILARIMGASITSDGFH
Mb2270|M.bovis_AF2122/97            CRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFH
Rv2246|M.tuberculosis_H37Rv         CRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFH
MLBr_01656|M.leprae_Br4923          CRPFDRDRDGFVFGEAGALMLIETEDSAKARSANILARIMGASITSDGFH
MAV_4343|M.avium_104                CRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYH
MSMEG_4328|M.smegmatis_MC2_155      CKPFDKDRNGFVFGEAGALMVIETEEHAKARGANILGRLMGASVTSDGYH
TH_2837|M.thermoresistible__bu      CKPFDKDRNGFVFGEAGALMVIETEEHAKARGANILGRLMGASITSDGYH
MAB_4608|M.abscessus_ATCC_1997      SRPFDKNRTGFVFGEGGALMVIETEEHAKARGARIYARLLGAGITSDGFH
                                    .:***::* ******.***::****: *:**.*   .*::**.:****:*

Mflv_2776|M.gilvum_PYR-GCK          MVAPDPDGERAGYAMTRAIELAGLTPTDIDHVNAHATGTSVGDVAEGRAI
Mvan_3757|M.vanbaalenii_PYR-1       MVAPDPNGERAGYAITRAIELAGLKPTDIDHVNAHATGTSVGDLAEGHAI
MMAR_3339|M.marinum_M               MVAPDPNGERAGHAITRAVQLAGLQPSDIDHVNAHATGTQVGDVAEGRAI
MUL_1303|M.ulcerans_Agy99           MVAPDPNGERAGHAITRAVQLAGLQPSDIDHVNAHATGTQVGDVAEGRAI
Mb2270|M.bovis_AF2122/97            MVAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAI
Rv2246|M.tuberculosis_H37Rv         MVAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAI
MLBr_01656|M.leprae_Br4923          MVAPDPNGERAGHAIARAVHLAGLSPSDIDHVNAHATGTQVGDLAEAKAI
MAV_4343|M.avium_104                MVAPDPNGERAGHAMSRAIQLAGLTPKDITHVNAHATGTSVGDVAEGKAI
MSMEG_4328|M.smegmatis_MC2_155      IVAPDPNGEQAGYAMTRAIELAGLKPTDIDHVNAHATGTNVGDVAESKAI
TH_2837|M.thermoresistible__bu      IVAPDPNGEQAGWAMTRAIELAGLQPSDIDHVNAHATGTTVGDVAEGKAI
MAB_4608|M.abscessus_ATCC_1997      VVAPHPDGIGAAKAMNRALETAGLDAKDIDHVNAHATATSVGDVAEGRAI
                                    :***.*:*  *. *: **:. *** . ** *******.* ***:**.:**

Mflv_2776|M.gilvum_PYR-GCK          NRALGGH--RPAVYAPKSALGHSVGAVGAVESILTVQALRDGVVPPTLNL
Mvan_3757|M.vanbaalenii_PYR-1       NLAMGGH--RPAVYAPKSALGHSVGAVGAVESILTVQSLRDGIIPPTLNL
MMAR_3339|M.marinum_M               NNALGSH--KPAVYAPKSALGHSVGAVGAVESILTVLALRDQVVPPTLNL
MUL_1303|M.ulcerans_Agy99           NNALGSH--KPAVYAPKSALGHSVGAVGAVESILTVLALRDQVVPPTLNL
Mb2270|M.bovis_AF2122/97            NNALGGN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNL
Rv2246|M.tuberculosis_H37Rv         NNALGGN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNL
MLBr_01656|M.leprae_Br4923          NKALCNN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNL
MAV_4343|M.avium_104                NNALGPHGGNAAVYAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNL
MSMEG_4328|M.smegmatis_MC2_155      NNAMGGH--KPAVYAPKGALGHSVGAVGAVESILTVLALRDGIIPPTRNL
TH_2837|M.thermoresistible__bu      NNAMKGH--RPAVYAPKAALGHSVGAVGAVESILTVFALRDGVIPPTLNL
MAB_4608|M.abscessus_ATCC_1997      HKSGLQH---AAVYAPKGALGHSVGAVGAVEAVITVKSLQEGIIPPTLNY
                                    : :   :   .******.*************:::** :*:: ::*** * 

Mflv_2776|M.gilvum_PYR-GCK          KNQDPEIDLDVVAGSPRPGNYNYALNNSFGFGGHNVALAFGKY
Mvan_3757|M.vanbaalenii_PYR-1       KNLDPEIDLDVVAGGPRPGNYEYAINNSFGFGGHNVALAFGKY
MMAR_3339|M.marinum_M               VNLDPEIDLDVVAGKPRPGNYRYAVNNSFGFGGHNVAITFGRY
MUL_1303|M.ulcerans_Agy99           VNLDPEIDLDVVAGKPRPGNYRYAVNNSFGFGGHNVAITFGRY
Mb2270|M.bovis_AF2122/97            VNLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
Rv2246|M.tuberculosis_H37Rv         VNLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
MLBr_01656|M.leprae_Br4923          VNLDPDIDLDVVAGKPRPGDYRYAVNNSFGFGGHNVAIAFGCY
MAV_4343|M.avium_104                ENLDPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY
MSMEG_4328|M.smegmatis_MC2_155      NNLDPEIDLDVVAGEPRQGDYKYAINNSFGFGGHNVALAFGKY
TH_2837|M.thermoresistible__bu      KNQDPEIDLDVVAGEPRTGDFKYAINNSFGFGGHNVALAFGKY
MAB_4608|M.abscessus_ATCC_1997      ETPDPEIDLDIVSKEPRKGDYKYAVNNSFGFGGHNVAIALGKY
                                     . **:****:*:  ** *::.**:************:::* *