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M. avium 104 MAV_2192 (-)

annotation: 3-oxoacyl-(acyl carrier protein) synthase II
coordinates: 2197533 - 2198783
length: 416

SKPSTANGGYPSVVVTAVTATTSIAPDVESTWKGLLAGESGIHVLEDDYITKWDLPVRIGGHLKEPIDER
MSRLDLRRMSYVQRLAKLLSTQLWETAGNPELDPDRFSVVVGTGLGGAERIVESYDLMNEGGPRKVSPLA
VQMIMPNGAAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFS
MMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLMGAGITSDAFHMVAPA
ADGVRAGRAMTRSLELAGLSPKDVDHVNAHGTATPIGDTAEANAIRVAGCQEAAVYAPKSALGHSIGAVG
ALESVLTVLTLRDGVIPPTLNYETPDPEIDLDIVAGEPRYGDYQYAINNSFGFGGHNVALAFGRY*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2192--100% (416)3-oxoacyl-(acyl carrier protein) synthase II
M. avium 104MAV_2191-e-15364.79% (409) 3-oxoacyl-(acyl carrier protein) synthase II
M. avium 104MAV_4343-e-14963.81% (409) 3-oxoacyl-(acyl carrier protein) synthase II

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2269kasA0.091.35% (416) 3-oxoacyl-(acyl carrier protein) synthase II
M. gilvum PYR-GCKMflv_2777-0.084.86% (416) 3-oxoacyl-(acyl carrier protein) synthase II
M. tuberculosis H37RvRv2245kasA0.091.35% (416) 3-oxoacyl-(acyl carrier protein) synthase II
M. leprae Br4923MLBr_01655kasA0.091.59% (416) 3-oxoacyl-(acyl carrier protein) synthase II
M. abscessus ATCC 19977MAB_1877c-0.080.34% (417) 3-oxoacyl-(acyl carrier protein) synthase II
M. marinum MMMAR_3338kasA0.092.07% (416) 3-oxoacyl-
M. smegmatis MC2 155MSMEG_4327-0.087.26% (416) 3-oxoacyl-(acyl carrier protein) synthase II
M. thermoresistible (build 8)TH_3425-0.088.56% (402) PUTATIVE beta-ketoacyl synthase
M. ulcerans Agy99MUL_1304kasA0.091.35% (416) 3-oxoacyl-(acyl carrier protein) synthase II
M. vanbaalenii PYR-1Mvan_3756-0.085.10% (416) 3-oxoacyl-(acyl carrier protein) synthase II

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4327|M.smegmatis_MC2_155      MTRPSTANGGYPNVVVTAVTATTSIAPDIESTWKGLLAGESGIRVLEDEF
Mvan_3756|M.vanbaalenii_PYR-1       MTRPSTANGGFPNVVVTAIEATTALAADIESTWKGLLAGESGIRILEDDF
Mflv_2777|M.gilvum_PYR-GCK          MTRPSTANGGFPNVVVTAVTATTSIAPDIESTWKGLLAGESGIRILEDEF
TH_3425|M.thermoresistible__bu      --------------VVTAVTATTSIAPDVEGTWKGLLAGESGIHVLEDDF
MMAR_3338|M.marinum_M               MTKPSTANGGYPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLDDEY
MUL_1304|M.ulcerans_Agy99           MTKPSTANGGYPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLDDEY
Mb2269|M.bovis_AF2122/97            MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEF
Rv2245|M.tuberculosis_H37Rv         MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEF
MLBr_01655|M.leprae_Br4923          MTMPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLEDEY
MAV_2192|M.avium_104                MSKPSTANGGYPSVVVTAVTATTSIAPDVESTWKGLLAGESGIHVLEDDY
MAB_1877c|M.abscessus_ATCC_199      MTLPSTANGGFPNVVVTALAATTSIAPDIEGTWKGLIAGESGIEVLEDEF
                                                  ****: ***:::.*:*.*****:******. *:*::

MSMEG_4327|M.smegmatis_MC2_155      VTKWDLPVRIGGHLVDNIDDHMTRLDMRRMSYVQRMSKFLSKQLWENAGA
Mvan_3756|M.vanbaalenii_PYR-1       VDKWDLPVRIGGHLVDDIDSHMTRIDKRRMSYVQRMSKLLARRLWDNAGT
Mflv_2777|M.gilvum_PYR-GCK          VEKWDLAVKIGGHLKEPLDPLMSRLEMRRMSYVQRMSKYLGNQLWDSIGR
TH_3425|M.thermoresistible__bu      IEKWDLPVRIGGHLKEAVDDHMTRIDIRRMSYVQRMAKLLSGRVWDAAGN
MMAR_3338|M.marinum_M               LTKWDLPVKIGGHLKDPVDNHMGRLDMRRMSYVQRMAKFLSGQLWESAGS
MUL_1304|M.ulcerans_Agy99           LTKWDLPVKIGGHLKDPVDNHMGRLDIRRMSYVQRMAKFLSGQLWESAGS
Mb2269|M.bovis_AF2122/97            VTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGS
Rv2245|M.tuberculosis_H37Rv         VTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGS
MLBr_01655|M.leprae_Br4923          ITKWDLPVKIGGHLKEPVDSHMSRLDLRRMSYVQRMSKLLSGRLWESTGS
MAV_2192|M.avium_104                ITKWDLPVRIGGHLKEPIDERMSRLDLRRMSYVQRLAKLLSTQLWETAGN
MAB_1877c|M.abscessus_ATCC_199      VEKFGLPVWIGGHLKEPIDNHMTRLELRRMAYVQRMALHVGRQVWQNAGS
                                    : *:.*.* ***** : :*  * *:: ***:****:.  :. ::*:  * 

MSMEG_4327|M.smegmatis_MC2_155      PE-VDPDRFAVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
Mvan_3756|M.vanbaalenii_PYR-1       PE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
Mflv_2777|M.gilvum_PYR-GCK          PE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
TH_3425|M.thermoresistible__bu      PE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
MMAR_3338|M.marinum_M               PE-VDPDRFTVVVGTGLGGAERIVESYDLMNEGGPRKVSPLAVQMIMPNG
MUL_1304|M.ulcerans_Agy99           PE-VDPDRFTVVVGTGLGGAERIVESYDLMNEGGPRKVSPLTVQMIMPNG
Mb2269|M.bovis_AF2122/97            PE-VDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNG
Rv2245|M.tuberculosis_H37Rv         PE-VDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNG
MLBr_01655|M.leprae_Br4923          PE-VDPDRFTVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNG
MAV_2192|M.avium_104                PE-LDPDRFSVVVGTGLGGAERIVESYDLMNEGGPRKVSPLAVQMIMPNG
MAB_1877c|M.abscessus_ATCC_199      PDDIDKDRLGVVIGTGLGGGERIVETYDTMNEHGIRKVSPLAVQMCMPNG
                                    *: :* **: **:******.*:***:** **  * ******:*** ****

MSMEG_4327|M.smegmatis_MC2_155      AAAVVGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGVE
Mvan_3756|M.vanbaalenii_PYR-1       AAAVAGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGVE
Mflv_2777|M.gilvum_PYR-GCK          AAAVVGLELGARAGVITPVSACSSGSEGIAHAWRQIVMGDADIAVCGGVE
TH_3425|M.thermoresistible__bu      AAAVVGLQLGARAGVITPVSACASGSEAIAHGWRQIVMGDADIAVVGGVE
MMAR_3338|M.marinum_M               AAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MUL_1304|M.ulcerans_Agy99           AAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
Mb2269|M.bovis_AF2122/97            AAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
Rv2245|M.tuberculosis_H37Rv         AAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MLBr_01655|M.leprae_Br4923          AAATVGLQLGACAGVMTPVSACSSGSEAIAHAWRQIIMGDADVAVCGGVE
MAV_2192|M.avium_104                AAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MAB_1877c|M.abscessus_ATCC_199      AAAVVGLEIGARAGVITPVSACSSGSEAIAHAWRQIVMGDADMIVCGGVE
                                    ***. **::** ***:******:****.***.****:*****. * ****

MSMEG_4327|M.smegmatis_MC2_155      GGIEALPIAAFSMMRAMSTRNDDPQGASRPFDKDRDGFVFGEAGAMMIIE
Mvan_3756|M.vanbaalenii_PYR-1       GGIEALPIAAFSMMRAMSTRNDDPAGASRPFDKDRDGFVFGEAGVMMIIE
Mflv_2777|M.gilvum_PYR-GCK          GGIEALPIAAFSMMRAMSTRNEDPEGASRPFDKNRDGFVFGEAGALMVIE
TH_3425|M.thermoresistible__bu      GGIEALPIAAFSMMRAMSTRNDDPEGASRPFDKDRDGFVFGEAGALMVIE
MMAR_3338|M.marinum_M               GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALLLIE
MUL_1304|M.ulcerans_Agy99           GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALLLIE
Mb2269|M.bovis_AF2122/97            GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIE
Rv2245|M.tuberculosis_H37Rv         GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIE
MLBr_01655|M.leprae_Br4923          GPIEALPIAAFSMMRAMSTRNDDPEGASRPFDKNRDGFVFGEAGALMLIE
MAV_2192|M.avium_104                GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIE
MAB_1877c|M.abscessus_ATCC_199      GMIEALPIAAFSMMRAMSTRNDEPEKASRPFDKDRDGFVFGEAGALMVIE
                                    * *******************::*  *******:**********.:::**

MSMEG_4327|M.smegmatis_MC2_155      TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGLRAGQAMKRAMETAG
Mvan_3756|M.vanbaalenii_PYR-1       TEEHAKARGATPLARLMGAGITSDAFHMVAPAADGVRAGHAMKRAMETAG
Mflv_2777|M.gilvum_PYR-GCK          TEEHALARGAKPLARLLGAGITSDAFHMVAPASDGQRAGSAMKRAMETAG
TH_3425|M.thermoresistible__bu      TEEHAKARGAQPLARLLGAGITSDAFHMVAPASDGVRAGHAMKRAMETAG
MMAR_3338|M.marinum_M               TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMQRSMELAG
MUL_1304|M.ulcerans_Agy99           TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMQRSMELAG
Mb2269|M.bovis_AF2122/97            TEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
Rv2245|M.tuberculosis_H37Rv         TEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
MLBr_01655|M.leprae_Br4923          TEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
MAV_2192|M.avium_104                TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
MAB_1877c|M.abscessus_ATCC_199      TEEHAKARGAQIIGRVMGAGITSDAYHMVAPGPDGIRAGAAMTRAIQTAG
                                    ***** ****  :.*::********:*****..** *** ** *::: **

MSMEG_4327|M.smegmatis_MC2_155      LDPKDIDHVNAHATATPIGDTAEANALRVAGVEHAAVYAPKSALGHSIGA
Mvan_3756|M.vanbaalenii_PYR-1       LSPKDISHVNAHATATPIGDTAEANAIRVAGVEHAAVYAPKSALGHSIGA
Mflv_2777|M.gilvum_PYR-GCK          LSPKDIDHVNAHATSTSIGDVAEANAIRVAGVEHAAVYAPKSALGHSIGA
TH_3425|M.thermoresistible__bu      LSPKDIDHVNAHATGTPIGDTAEANAIRVAGVEHAPVYAPKSALGHSIGA
MMAR_3338|M.marinum_M               LSPKDIDHVNAHGTATPIGDSAEANAIRVAGCENAAIYAPKSALGHSIGA
MUL_1304|M.ulcerans_Agy99           LSPTDIDHVNAHGTATPIGDSAEANAIRVAGFENAAIYAPKSALGHSIGA
Mb2269|M.bovis_AF2122/97            LSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGA
Rv2245|M.tuberculosis_H37Rv         LSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGA
MLBr_01655|M.leprae_Br4923          LSAKDVDHVNAHGTATPIGDSAEANAIRVAGCEQAAVYAPKSALGHSIGA
MAV_2192|M.avium_104                LSPKDVDHVNAHGTATPIGDTAEANAIRVAGCQEAAVYAPKSALGHSIGA
MAB_1877c|M.abscessus_ATCC_199      LSPKDIDHINAHGTATPIGDVAEANAIHVAGVQHAAVYAPKSALGHSIGA
                                    *.. *:.*:***.*.*.*** *****::*** :.*.:*************

MSMEG_4327|M.smegmatis_MC2_155      VGALESILTVLALRDGVIPPTLNYETPDPEIDLDIVAGEPRYGEYKYAIN
Mvan_3756|M.vanbaalenii_PYR-1       VGALESALTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYQYAIN
Mflv_2777|M.gilvum_PYR-GCK          VGALESILTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYKYAIN
TH_3425|M.thermoresistible__bu      VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDIVAGEPRYGDYRYAIN
MMAR_3338|M.marinum_M               VGALESALTVLSLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGEFQYAIN
MUL_1304|M.ulcerans_Agy99           VGALESALTVLSLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGEFQYAIN
Mb2269|M.bovis_AF2122/97            VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVN
Rv2245|M.tuberculosis_H37Rv         VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVN
MLBr_01655|M.leprae_Br4923          VGALESVLTVLALRDGVIPPTLNYQTPDPEIDLDIVAGEPRYGDYRYAIN
MAV_2192|M.avium_104                VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDIVAGEPRYGDYQYAIN
MAB_1877c|M.abscessus_ATCC_199      VGALESVLTVLALRDGVIPPTLNLDNLDPEIDLDVVAGEPRHGDFKYAIN
                                    ****** ****:*********** :. *******:******:*:::**:*

MSMEG_4327|M.smegmatis_MC2_155      NSFGFGGHNVALAFGRY
Mvan_3756|M.vanbaalenii_PYR-1       NSFGFGGHNVALAFGRY
Mflv_2777|M.gilvum_PYR-GCK          NSFGFGGHNVALAFGRY
TH_3425|M.thermoresistible__bu      NSFGFGGHNVALAFGRY
MMAR_3338|M.marinum_M               NSFGFGGHNVALAFGRY
MUL_1304|M.ulcerans_Agy99           NSFGFGGHNVALAFGRY
Mb2269|M.bovis_AF2122/97            NSFGFGGHNVALAFGRY
Rv2245|M.tuberculosis_H37Rv         NSFGFGGHNVALAFGRY
MLBr_01655|M.leprae_Br4923          NSFGFGGHNVALAFGRY
MAV_2192|M.avium_104                NSFGFGGHNVALAFGRY
MAB_1877c|M.abscessus_ATCC_199      NSFGFGGHNVALAFGKY
                                    ***************:*