For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAKPSTANGGFPNIVVTGMAMTTSIAPDVEGTWKGLLNGESGIRVLDDDFVAQYDLPVKIGGHLKVRDFD KDMTKIELRRLSYVQRLAAILGRQVWEDAGAPEDIDLERLTVSVGTGLGGGEKLVEAYDEMRARGTKAVS PLTVQMFMPNGPAAVIGLERKARGGVITPVSACASGNEGIAHAWRQIAYGDADIAICGGIEAAIEAAPIA AFANMRIVMSTDNDNPAGASRPFDKNRTGFVFGEGGALMVIETEEHAKARGARIYARLLGAGITSDGFHV VAPHPDGIGAAKAMNRALETAGLDAKDIDHVNAHATATSVGDVAEGRAIHKSGLQHAAVYAPKGALGHSV GAVGAVEAVITVKSLQEGIIPPTLNYETPDPEIDLDIVSKEPRKGDYKYAVNNSFGFGGHNVAIALGKY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4608 | - | - | 100% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. abscessus ATCC 19977 | MAB_1877c | - | e-172 | 69.71% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. abscessus ATCC 19977 | MAB_2030 | - | 6e-54 | 33.18% (425) | 3-oxoacyl-(Acyl-carrier-protein) synthase II KasA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2269 | kasA | 1e-166 | 67.54% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. gilvum PYR-GCK | Mflv_2777 | - | 1e-173 | 69.93% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. tuberculosis H37Rv | Rv2245 | kasA | 1e-166 | 67.54% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. leprae Br4923 | MLBr_01655 | kasA | 1e-167 | 67.55% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. marinum M | MMAR_3338 | kasA | 1e-165 | 66.35% (419) | 3-oxoacyl- |
| M. avium 104 | MAV_2192 | - | 1e-168 | 68.26% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. smegmatis MC2 155 | MSMEG_4327 | - | 1e-174 | 69.21% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. thermoresistible (build 8) | TH_2837 | - | 1e-166 | 68.80% (407) | PUTATIVE beta-ketoacyl synthase |
| M. ulcerans Agy99 | MUL_1304 | kasA | 1e-165 | 66.35% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. vanbaalenii PYR-1 | Mvan_3756 | - | 1e-170 | 68.26% (419) | 3-oxoacyl-(acyl carrier protein) synthase II |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2269|M.bovis_AF2122/97 MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEF
Rv2245|M.tuberculosis_H37Rv MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEF
MLBr_01655|M.leprae_Br4923 MTMPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLEDEY
MMAR_3338|M.marinum_M MTKPSTANGGYPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLDDEY
MUL_1304|M.ulcerans_Agy99 MTKPSTANGGYPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLDDEY
MAV_2192|M.avium_104 MSKPSTANGGYPSVVVTAVTATTSIAPDVESTWKGLLAGESGIHVLEDDY
MSMEG_4327|M.smegmatis_MC2_155 MTRPSTANGGYPNVVVTAVTATTSIAPDIESTWKGLLAGESGIRVLEDEF
Mvan_3756|M.vanbaalenii_PYR-1 MTRPSTANGGFPNVVVTAIEATTALAADIESTWKGLLAGESGIRILEDDF
Mflv_2777|M.gilvum_PYR-GCK MTRPSTANGGFPNVVVTAVTATTSIAPDIESTWKGLLAGESGIRILEDEF
MAB_4608|M.abscessus_ATCC_1997 MAKPSTANGGFPNIVVTGMAMTTSIAPDVEGTWKGLLNGESGIRVLDDDF
TH_2837|M.thermoresistible__bu -------------VVVTGVAMTTALATDAEGTWKKLLDGQSGIRLLEDDF
:***.: **:::.* *.*** ** *:***: *:*::
Mb2269|M.bovis_AF2122/97 VTKWDLAVKIGGHL-KDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAG
Rv2245|M.tuberculosis_H37Rv VTKWDLAVKIGGHL-KDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAG
MLBr_01655|M.leprae_Br4923 ITKWDLPVKIGGHL-KEPVDSHMSRLDLRRMSYVQRMSKLLSGRLWESTG
MMAR_3338|M.marinum_M LTKWDLPVKIGGHL-KDPVDNHMGRLDMRRMSYVQRMAKFLSGQLWESAG
MUL_1304|M.ulcerans_Agy99 LTKWDLPVKIGGHL-KDPVDNHMGRLDIRRMSYVQRMAKFLSGQLWESAG
MAV_2192|M.avium_104 ITKWDLPVRIGGHL-KEPIDERMSRLDLRRMSYVQRLAKLLSTQLWETAG
MSMEG_4327|M.smegmatis_MC2_155 VTKWDLPVRIGGHL-VDNIDDHMTRLDMRRMSYVQRMSKFLSKQLWENAG
Mvan_3756|M.vanbaalenii_PYR-1 VDKWDLPVRIGGHL-VDDIDSHMTRIDKRRMSYVQRMSKLLARRLWDNAG
Mflv_2777|M.gilvum_PYR-GCK VEKWDLAVKIGGHL-KEPLDPLMSRLEMRRMSYVQRMSKYLGNQLWDSIG
MAB_4608|M.abscessus_ATCC_1997 VAQYDLPVKIGGHLKVRDFDKDMTKIELRRLSYVQRLAAILGRQVWEDAG
TH_2837|M.thermoresistible__bu IEKYDLPVRIGGHL-LEDFDSELTRVELRRLSYLQKMSTVLSRRVWENAG
: ::**.*:***** .* : ::: **:**:*::. *. ::*: *
Mb2269|M.bovis_AF2122/97 SPE-VDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPN
Rv2245|M.tuberculosis_H37Rv SPE-VDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPN
MLBr_01655|M.leprae_Br4923 SPE-VDPDRFTVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPN
MMAR_3338|M.marinum_M SPE-VDPDRFTVVVGTGLGGAERIVESYDLMNEGGPRKVSPLAVQMIMPN
MUL_1304|M.ulcerans_Agy99 SPE-VDPDRFTVVVGTGLGGAERIVESYDLMNEGGPRKVSPLTVQMIMPN
MAV_2192|M.avium_104 NPE-LDPDRFSVVVGTGLGGAERIVESYDLMNEGGPRKVSPLAVQMIMPN
MSMEG_4327|M.smegmatis_MC2_155 APE-VDPDRFAVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPN
Mvan_3756|M.vanbaalenii_PYR-1 TPE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPN
Mflv_2777|M.gilvum_PYR-GCK RPE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPN
MAB_4608|M.abscessus_ATCC_1997 APEDIDLERLTVSVGTGLGGGEKLVEAYDEMRARGTKAVSPLTVQMFMPN
TH_2837|M.thermoresistible__bu SPE-VDPRRLMVSIGTGMGSTEELVFSYDDMRAKGLKAVSPLAVQKYMPN
** :* *: * :***:*. *.:* :** *. * : ****:** ***
Mb2269|M.bovis_AF2122/97 GAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGV
Rv2245|M.tuberculosis_H37Rv GAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGV
MLBr_01655|M.leprae_Br4923 GAAATVGLQLGACAGVMTPVSACSSGSEAIAHAWRQIIMGDADVAVCGGV
MMAR_3338|M.marinum_M GAAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGV
MUL_1304|M.ulcerans_Agy99 GAAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGV
MAV_2192|M.avium_104 GAAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGV
MSMEG_4327|M.smegmatis_MC2_155 GAAAVVGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGV
Mvan_3756|M.vanbaalenii_PYR-1 GAAAVAGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGV
Mflv_2777|M.gilvum_PYR-GCK GAAAVVGLELGARAGVITPVSACSSGSEGIAHAWRQIVMGDADIAVCGGV
MAB_4608|M.abscessus_ATCC_1997 GPAAVIGLERKARGGVITPVSACASGNEGIAHAWRQIAYGDADIAICGGI
TH_2837|M.thermoresistible__bu AAAAAVGLERKARAGVITPVSACASGSEGIAHAWRNIVLGEADIAICGGV
..**. **: * .**:******:**.*.******:* *:**.*:***:
Mb2269|M.bovis_AF2122/97 EGPIEALPIAAFSMMR-AMSTRNDEPERASRPFDKDRDGFVFGEAGALML
Rv2245|M.tuberculosis_H37Rv EGPIEALPIAAFSMMR-AMSTRNDEPERASRPFDKDRDGFVFGEAGALML
MLBr_01655|M.leprae_Br4923 EGPIEALPIAAFSMMR-AMSTRNDDPEGASRPFDKNRDGFVFGEAGALML
MMAR_3338|M.marinum_M EGPIEALPIAAFSMMR-AMSTRNDEPERASRPFDKDRDGFVFGEAGALLL
MUL_1304|M.ulcerans_Agy99 EGPIEALPIAAFSMMR-AMSTRNDEPERASRPFDKDRDGFVFGEAGALLL
MAV_2192|M.avium_104 EGPIEALPIAAFSMMR-AMSTRNDEPERASRPFDKDRDGFVFGEAGALML
MSMEG_4327|M.smegmatis_MC2_155 EGGIEALPIAAFSMMR-AMSTRNDDPQGASRPFDKDRDGFVFGEAGAMMI
Mvan_3756|M.vanbaalenii_PYR-1 EGGIEALPIAAFSMMR-AMSTRNDDPAGASRPFDKDRDGFVFGEAGVMMI
Mflv_2777|M.gilvum_PYR-GCK EGGIEALPIAAFSMMR-AMSTRNEDPEGASRPFDKNRDGFVFGEAGALMV
MAB_4608|M.abscessus_ATCC_1997 EAAIEAAPIAAFANMRIVMSTDNDNPAGASRPFDKNRTGFVFGEGGALMV
TH_2837|M.thermoresistible__bu ETKIEAVPIAGFAQMRIVLSTTNDDPPGACKPFDKDRNGFVFGEAGALMV
* *** ***.*: ** .:** *::* *.:****:* ******.*.:::
Mb2269|M.bovis_AF2122/97 IETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLEL
Rv2245|M.tuberculosis_H37Rv IETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLEL
MLBr_01655|M.leprae_Br4923 IETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLEL
MMAR_3338|M.marinum_M IETEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMQRSMEL
MUL_1304|M.ulcerans_Agy99 IETEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMQRSMEL
MAV_2192|M.avium_104 IETEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMTRSLEL
MSMEG_4327|M.smegmatis_MC2_155 IETEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGLRAGQAMKRAMET
Mvan_3756|M.vanbaalenii_PYR-1 IETEEHAKARGATPLARLMGAGITSDAFHMVAPAADGVRAGHAMKRAMET
Mflv_2777|M.gilvum_PYR-GCK IETEEHALARGAKPLARLLGAGITSDAFHMVAPASDGQRAGSAMKRAMET
MAB_4608|M.abscessus_ATCC_1997 IETEEHAKARGARIYARLLGAGITSDGFHVVAPHPDGIGAAKAMNRALET
TH_2837|M.thermoresistible__bu IETEEHAKARGANILGRLMGASITSDGYHIVAPDPNGEQAGWAMTRAIEL
******* **** .**:**.****.:*:*** .:* *. ** *::*
Mb2269|M.bovis_AF2122/97 AGLSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQ-AAVYAPKSALGHS
Rv2245|M.tuberculosis_H37Rv AGLSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQ-AAVYAPKSALGHS
MLBr_01655|M.leprae_Br4923 AGLSAKDVDHVNAHGTATPIGDSAEANAIRVAGCEQ-AAVYAPKSALGHS
MMAR_3338|M.marinum_M AGLSPKDIDHVNAHGTATPIGDSAEANAIRVAGCEN-AAIYAPKSALGHS
MUL_1304|M.ulcerans_Agy99 AGLSPTDIDHVNAHGTATPIGDSAEANAIRVAGFEN-AAIYAPKSALGHS
MAV_2192|M.avium_104 AGLSPKDVDHVNAHGTATPIGDTAEANAIRVAGCQE-AAVYAPKSALGHS
MSMEG_4327|M.smegmatis_MC2_155 AGLDPKDIDHVNAHATATPIGDTAEANALRVAGVEH-AAVYAPKSALGHS
Mvan_3756|M.vanbaalenii_PYR-1 AGLSPKDISHVNAHATATPIGDTAEANAIRVAGVEH-AAVYAPKSALGHS
Mflv_2777|M.gilvum_PYR-GCK AGLSPKDIDHVNAHATSTSIGDVAEANAIRVAGVEH-AAVYAPKSALGHS
MAB_4608|M.abscessus_ATCC_1997 AGLDAKDIDHVNAHATATSVGDVAEGRAIHKSGLQH-AAVYAPKGALGHS
TH_2837|M.thermoresistible__bu AGLQPSDIDHVNAHATGTTVGDVAEGKAINNAMKGHRPAVYAPKAALGHS
***.. *:.*****.*.*.:** **..*:. : . .*:****.*****
Mb2269|M.bovis_AF2122/97 IGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRY
Rv2245|M.tuberculosis_H37Rv IGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRY
MLBr_01655|M.leprae_Br4923 IGAVGALESVLTVLALRDGVIPPTLNYQTPDPEIDLDIVAGEPRYGDYRY
MMAR_3338|M.marinum_M IGAVGALESALTVLSLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGEFQY
MUL_1304|M.ulcerans_Agy99 IGAVGALESALTVLSLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGEFQY
MAV_2192|M.avium_104 IGAVGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDIVAGEPRYGDYQY
MSMEG_4327|M.smegmatis_MC2_155 IGAVGALESILTVLALRDGVIPPTLNYETPDPEIDLDIVAGEPRYGEYKY
Mvan_3756|M.vanbaalenii_PYR-1 IGAVGALESALTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYQY
Mflv_2777|M.gilvum_PYR-GCK IGAVGALESILTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYKY
MAB_4608|M.abscessus_ATCC_1997 VGAVGAVEAVITVKSLQEGIIPPTLNYETPDPEIDLDIVSKEPRKGDYKY
TH_2837|M.thermoresistible__bu VGAVGAVESILTVFALRDGVIPPTLNLKNQDPEIDLDVVAGEPRTGDFKY
:*****:*: :** :*::*:****** :. *******:*: *** *:::*
Mb2269|M.bovis_AF2122/97 AVNNSFGFGGHNVALAFGRY
Rv2245|M.tuberculosis_H37Rv AVNNSFGFGGHNVALAFGRY
MLBr_01655|M.leprae_Br4923 AINNSFGFGGHNVALAFGRY
MMAR_3338|M.marinum_M AINNSFGFGGHNVALAFGRY
MUL_1304|M.ulcerans_Agy99 AINNSFGFGGHNVALAFGRY
MAV_2192|M.avium_104 AINNSFGFGGHNVALAFGRY
MSMEG_4327|M.smegmatis_MC2_155 AINNSFGFGGHNVALAFGRY
Mvan_3756|M.vanbaalenii_PYR-1 AINNSFGFGGHNVALAFGRY
Mflv_2777|M.gilvum_PYR-GCK AINNSFGFGGHNVALAFGRY
MAB_4608|M.abscessus_ATCC_1997 AVNNSFGFGGHNVAIALGKY
TH_2837|M.thermoresistible__bu AINNSFGFGGHNVALAFGKY
*:************:*:*:*