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RIAIVSGDDVVGEDPEQLGAALAAQGHDVTTCLRRAGRRRGGSAPDGYRRVSVPVGPRDAAAPVDVLPYV GDWAGALERIWSKDRPDVVHAYGWLGGLAAQLAARRRHIPTVQSFLGLAATARGHDGERGTERQRIEPLL ARSANWVTGESSADVDALARLRRRRVRVSALTCGVDAERYTPTGPADSRGALQRILYVAPNPLWHNGIDL AIRALPKVRGAELVIAETDPGGDGHDGARARLLRLSVHLGVADRVRFAGPVGGDELPRLLRSADVLVCTP RRPPRPTPVLQAMASGVVVVVATVGVLSDVVLDDITGIVVSPENPARLAAALRRLLAQKFQCESMGAAGR SRAQSRFAWQRIALDALNIYQSLGVHEPAAPLDGDAVLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4064 | - | - | 100% (390) | glycosyl transferase, group 1 family protein |
| M. avium 104 | MAV_4082 | - | 3e-69 | 41.99% (381) | transferase |
| M. avium 104 | MAV_3879 | - | 1e-21 | 25.89% (394) | glycosyl transferase, group 1 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 8e-22 | 27.44% (390) | transferase |
| M. gilvum PYR-GCK | Mflv_3449 | - | 3e-51 | 38.34% (373) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv3032 | - | 8e-22 | 27.44% (390) | transferase |
| M. leprae Br4923 | MLBr_01715 | - | 9e-21 | 25.32% (391) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3366 | - | 2e-24 | 29.02% (386) | glycosyltransferase |
| M. marinum M | MMAR_1681 | - | 8e-21 | 25.77% (388) | transferase |
| M. smegmatis MC2 155 | MSMEG_0933 | - | 9e-15 | 27.05% (292) | hypothetical protein MSMEG_0933 |
| M. thermoresistible (build 8) | TH_3188 | - | 1e-72 | 41.41% (384) | PUTATIVE glycosyl transferase, group 1 |
| M. ulcerans Agy99 | MUL_1919 | - | 9e-21 | 25.52% (388) | transferase |
| M. vanbaalenii PYR-1 | Mvan_3205 | - | 2e-54 | 37.90% (372) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1681|M.marinum_M ------------------------MKILMVSWEYP---PVVIGGLGRHVH
MUL_1919|M.ulcerans_Agy99 ------------------------MKILMVSWEYP---PVVIGGLGRHVH
Mb3058|M.bovis_AF2122/97 ------------------------MRILMVSWEYP---PVVIGGLGRHVH
Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYP---PVVIGGLGRHVH
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYP---PVVIGGLGRHVH
MAB_3366|M.abscessus_ATCC_1997 ------------------------MRILMVSWEYP---PVVIGGLGRHVH
MAV_4064|M.avium_104 ------------------------MRIAIVSGDD-------VVGE--DPE
TH_3188|M.thermoresistible__bu ------------------MVSEHASPLAALGGVD-------AGGQNVHVA
Mflv_3449|M.gilvum_PYR-GCK ------------------------MRLAVVGDLSGVGATDRGGGGRYGIA
Mvan_3205|M.vanbaalenii_PYR-1 ------------------------MKLALVGELP--------GGHGYDLT
MSMEG_0933|M.smegmatis_MC2_155 -----------MRLATDLETPRRVAVLSVHTSPLAQPGTGDAGGMNVYVL
: *
MMAR_1681|M.marinum_M HLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEF
MUL_1919|M.ulcerans_Agy99 HLATALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEF
Mb3058|M.bovis_AF2122/97 HLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEF
Rv3032|M.tuberculosis_H37Rv HLSTALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEF
MLBr_01715|M.leprae_Br4923 HLSTALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDPHEF
MAB_3366|M.abscessus_ATCC_1997 HLSTELAAAGHDVVVLTRRPSGTDPSSHPTSDEISEGVRVVAAAEDPHDF
MAV_4064|M.avium_104 QLGAALAAQGHDVTTCLRRAGRRRGG------SAPDGYRRVSVPVGPRDA
TH_3188|M.thermoresistible__bu ELSAALTRRGHEVTVYTRRDDRGLPDRV----DTPLGYTVVHVPAGPAEQ
Mflv_3449|M.gilvum_PYR-GCK DLAQALARRGHEVRVHTALPHPAGVQ--------PTGVAVDHVPVATVAV
Mvan_3205|M.vanbaalenii_PYR-1 RLGDALVGRGHKVQVFTATVPAMRYT--------PAGAAVQRLPVDTTGV
MSMEG_0933|M.smegmatis_MC2_155 QTALQLARRGVEVEVFTRATSSADAPVVP----VAPGVLVRNVVAGPFEG
. *. * .* . . * .
MMAR_1681|M.marinum_M SFGSDMMAWTLAMGHAMVRAGLTLSGPGAEQPWQPDIVHAHDWLVAHPAI
MUL_1919|M.ulcerans_Agy99 SFGSDMMAWTLAMGHAMVRAGLTLSGPGAEQPWQPDIVHAHDWLVAHPAI
Mb3058|M.bovis_AF2122/97 TFGNDMMAWTLAMGHAMIRAGLRLKKLGTDRSWRPDVVHAHDWLVAHPAI
Rv3032|M.tuberculosis_H37Rv TFGNDMMAWTLAMGHAMIRAGLRLKKLGTDRSWRPDVVHAHDWLVAHPAI
MLBr_01715|M.leprae_Br4923 TFSNDMMAWTLAMGHAMIRTGLSLTRHSSDLPWRPDVVHAHDWLVAHPAI
MAB_3366|M.abscessus_ATCC_1997 DFGTDMMAWTLAMGHAMVRAGLALGLKGSGD-WRPDVVHAHDWLVAHPAI
MAV_4064|M.avium_104 AAPVDVLPYVGDWAGALERIWSKD---------RPDVVHAYGWLGGLAAQ
TH_3188|M.thermoresistible__bu LPKDELLPYMGPFAQFLDAEWSAH---------RPDVVHAHFWMSGIATQ
Mflv_3449|M.gilvum_PYR-GCK ETSPELMPAIGEISRHLVDVWRRD---------TPDVVHCHGWVYGMAAQ
Mvan_3205|M.vanbaalenii_PYR-1 ESSEDLMPLIGEMGRHLVDVWEAD---------GPDVVHCHGWVYGMAAQ
MSMEG_0933|M.smegmatis_MC2_155 LDKNDLPTQLCAFTAGVLRAEATHEPG------YYDVVHSHYWLSGQVGW
:: . : *:**.: *: .
MMAR_1681|M.marinum_M ALADYYDVPMVSTIHATEAGRHSGWVSGDLS--RQVHAVESWLVRESDSL
MUL_1919|M.ulcerans_Agy99 ALADYYDVPMVSTIHATEAGRHSGWVSGDLS--RQVHAVESWLVRESDSL
Mb3058|M.bovis_AF2122/97 ALAQFYDVPMVSTIHATEAGRHSGWVSGALS--RQVHAVESWLVRESDSL
Rv3032|M.tuberculosis_H37Rv ALAQFYDVPMVSTIHATEAGRHSGWVSGALS--RQVHAVESWLVRESDSL
MLBr_01715|M.leprae_Br4923 TLAQFYDVPMVSTIHATEAGRHSGWVSGALS--RQVHAVESWLVRESDSL
MAB_3366|M.abscessus_ATCC_1997 ALAEHFDVPLVSTLHATEAGRHSGWVSGRIS--RQVHSVEWWLARESDSL
MAV_4064|M.avium_104 LAARRRHIPTVQSFLGLAATARGHDGERGT----ERQRIEPLLARSANWV
TH_3188|M.thermoresistible__bu LASRHLDLPAVQTFHALGVVKKRHQGAEDTSP-QERLQLEAMVARGANWV
Mflv_3449|M.gilvum_PYR-GCK LAAKKTPVPIVQTFHELSTPGRRESAGGQAA---TAAKLEALLARNATAL
Mvan_3205|M.vanbaalenii_PYR-1 LAARRCRIPTVQSFPELSVSAGGDRGEGLAD---KRIQLEALLARNATAV
MSMEG_0933|M.smegmatis_MC2_155 LARDRWAVPLVHTAHTLAAVKNAALAAGDAPEPPLRAVGEQQVVDEADRL
:* * : . * :. : :
MMAR_1681|M.marinum_M ITCSGSMSDEITELFGPGLAETAVIRNGIDAAR-WPFAVRKPRTG-----
MUL_1919|M.ulcerans_Agy99 ITCSGSMSDEITELFGPGLAETAVIRNGIDVAR-WPFAVRKPRTG-----
Mb3058|M.bovis_AF2122/97 ITCSASMNDEITELFGPGLAEITVIRNGIDAAR-WPFAARRPRTG-----
Rv3032|M.tuberculosis_H37Rv ITCSASMNDEITELFGPGLAEITVIRNGIDAAR-WPFAARRPRTG-----
MLBr_01715|M.leprae_Br4923 ITCSASMCNEIIELFGPGLAEITVIRNGIDPAR-WPFAARRARTG-----
MAB_3366|M.abscessus_ATCC_1997 ITCSASMLDEVTQLFGPELPQVHVIRNGIDVTR-WVFAPRPPADGT----
MAV_4064|M.avium_104 TGESSADVDALARLRRR-RVRVSALTCGVDAERYTPTGPADSRGAL----
TH_3188|M.thermoresistible__bu AATCTDEVFELMRMGRS-RSRISVVPCGVDLDLFTPDGPQAPRGER----
Mflv_3449|M.gilvum_PYR-GCK TAGCHDDVQTLIRLGCP-RAKVSVLSAGVEVDD--AVEIESRGGDV----
Mvan_3205|M.vanbaalenii_PYR-1 TVACNDDMREIIRLGCT-RAKASVLAPGIDVDDVCAEEIVFRHGES----
MSMEG_0933|M.smegmatis_MC2_155 IVNTEVEAQQLVSLHNADRSRIDVVHPGVDLDVFTPGSRDAARAVFGLPT
: : . .: *::
MMAR_1681|M.marinum_M PPELLYVG-RLEYEKGVHNAIAALPRIRRAHPGTTLTIAG----EGTQQD
MUL_1919|M.ulcerans_Agy99 PPELLYVG-RLEYEKGVHNAIAALPRIRRAHPGTTLTIAG----EGTQQD
Mb3058|M.bovis_AF2122/97 PAELLYVG-RLEYEKGVHDAIAALPRLRRTHPGTTLTIAG----EGTQQD
Rv3032|M.tuberculosis_H37Rv PAELLYVG-RLEYEKGVHDAIAALPRLRRTHPGTTLTIAG----EGTQQD
MLBr_01715|M.leprae_Br4923 PAELLYVG-RLEYEKGVHDVIAALPRIRRSYPGTTLTIAG----EGTQQD
MAB_3366|M.abscessus_ATCC_1997 PPVLLFVG-RLEYEKGIHDAIAALPKIRRAHPGTVLAVAG----DGTQQD
MAV_4064|M.avium_104 Q-RILYVAPNPLWHNGIDLAIRALPKVRGAELVIAETDPGGDGHDGARAR
TH_3188|M.thermoresistible__bu R-RIVTVG-RFVPRKGFDTLVRALPAIPNAELVVVGGPRRSQLRTEPEAR
Mflv_3449|M.gilvum_PYR-GCK PPRIVAVARDFGAEQGLADVVAALPSLGAADLTLVATDP-----TGPDAG
Mvan_3205|M.vanbaalenii_PYR-1 SGRVVAVARDFSPQQGLGQVLRVFPSSNAAELVLVTREPD----DGPDYD
MSMEG_0933|M.smegmatis_MC2_155 DQKIVAFVGRIQPLKAPDILLRAAAKLPGVRVLIAGGPSGS---GLAQPD
:: . :. : . . . .
MMAR_1681|M.marinum_M WLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHYEPFGLVAL
MUL_1919|M.ulcerans_Agy99 WLVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPSHYEPFGLVAL
Mb3058|M.bovis_AF2122/97 WLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFGLVAL
Rv3032|M.tuberculosis_H37Rv WLIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPSHYEPFGLVAL
MLBr_01715|M.leprae_Br4923 WLVDQARKYKVIKATRFVGHLNHNELLAALQRADAAVLPSHYEPFGLVAL
MAB_3366|M.abscessus_ATCC_1997 WLLEQARKYKVVKSVQFLGTLDHSELLHWLHHADAILLPSHYEPFGIVAL
MAV_4064|M.avium_104 -LLRLSVHLGVADRVRFAGPVGGDELPRLLRSADVLVCTPRRPPRPTPVL
TH_3188|M.thermoresistible__bu RLCTLAEELGVADRVQLYGSVARADMPAVLRSADVVACTPWYEPFGIVPL
Mflv_3449|M.gilvum_PYR-GCK HLGDVARRLRVADRVRMMRGDECPELAALLPSADVVVLPARYEPSSEFVL
Mvan_3205|M.vanbaalenii_PYR-1 DILSLAREKKAAKRVNLVAGAAGDDLTTLFRSADVVVAPARYEPSCATVL
MSMEG_0933|M.smegmatis_MC2_155 TLVRLADELGISDRVTFLPPQSREQLVNVYRAADLVAVPSYSESFGLVAV
: : . . : :: ** .. . :
MMAR_1681|M.marinum_M EAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVLDDPA
MUL_1919|M.ulcerans_Agy99 EAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVLDDPA
Mb3058|M.bovis_AF2122/97 EAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPA
Rv3032|M.tuberculosis_H37Rv EAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPA
MLBr_01715|M.leprae_Br4923 EAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVLEDPD
MAB_3366|M.abscessus_ATCC_1997 EAAAAGTPLVTSTVGGLGEAVIDGETGMSFAPRDVAGIAEAVTRTLDDPA
MAV_4064|M.avium_104 QAMASGVVVVVATVGVLSDVVLDDITGIVVSPENPARLAAALRRLLAQKF
TH_3188|M.thermoresistible__bu EAMACGVPVVAAAVGGMLDTVVHDVTGRLVPPRRPAELADTINQLLRDSF
Mflv_3449|M.gilvum_PYR-GCK QAMACGAPVVAFAAGGARDAVIEDVTGLLVQPGDVNALGRAVRTALSQPV
Mvan_3205|M.vanbaalenii_PYR-1 QAMACGAPIVATSAGGARDAVIGEVTGLLVPPGNADALGRALRSTLGQMV
MSMEG_0933|M.smegmatis_MC2_155 EAQACGTPVVAAAVGGLPVAVADGVSGALVDGHDIGDWADTISEVLDREP
:* *.*. :*. * .* :* . : *
MMAR_1681|M.marinum_M AAQQRARAARERLNSDFDWQTVAEQTAQVYLAAKRGERQPLPRLPIVEHA
MUL_1919|M.ulcerans_Agy99 AAQQRARAARERLNSNFDWQTVAEQTAQVYLAAKRGERQPLPRLPIVEHA
Mb3058|M.bovis_AF2122/97 AAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHA
Rv3032|M.tuberculosis_H37Rv AAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHA
MLBr_01715|M.leprae_Br4923 AAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRLPIVEHA
MAB_3366|M.abscessus_ATCC_1997 AAAERAVAARARLTADFDWATVADETAQVYLAAKRREREPLGRSVIVERP
MAV_4064|M.avium_104 QCESMGAAGRSRAQSRFAWQRIALDALNIYQSLGVHEPAAPLDGDAVLR-
TH_3188|M.thermoresistible__bu LRQSLGAAGRDRARARYSWDRVATDTQRIYDRLVPADYRSATASQMSSG-
Mflv_3449|M.gilvum_PYR-GCK LRQGMGLAGRSRARSRYSWDRIATDAEVAYLAAAARHSGQAPAGDRGPGT
Mvan_3205|M.vanbaalenii_PYR-1 LREGMGLAGRSRARSRYSWDRIATDAEVVYASATTRESAFAC--------
MSMEG_0933|M.smegmatis_MC2_155 AALSRASAEH---AAQFSWAHTVDALLASYSRAMSDYRARHPRPAARRSG
. * : : : * . *
MMAR_1681|M.marinum_M LPDR-----------
MUL_1919|M.ulcerans_Agy99 LPDR-----------
Mb3058|M.bovis_AF2122/97 LPDR-----------
Rv3032|M.tuberculosis_H37Rv LPDR-----------
MLBr_01715|M.leprae_Br4923 LPDR-----------
MAB_3366|M.abscessus_ATCC_1997 LPDR-----------
MAV_4064|M.avium_104 ---------------
TH_3188|M.thermoresistible__bu ---------------
Mflv_3449|M.gilvum_PYR-GCK RGSLRPQSCSPVTRK
Mvan_3205|M.vanbaalenii_PYR-1 ---------------
MSMEG_0933|M.smegmatis_MC2_155 RRFSMRRGVRT----