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M. thermoresistible (build 8) TH_2373 (wag31)

annotation: CONSERVED HYPOTHETICAL PROTEIN WAG31
coordinates: 4645667 - 4646461
length: 265

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2373wag31-100% (265)CONSERVED HYPOTHETICAL PROTEIN WAG31
M. thermoresistible (build 8)TH_1226-4e-1229.78% (178) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2169cwag311e-11078.79% (264) hypothetical protein Mb2169c
M. gilvum PYR-GCKMflv_2996-1e-11778.18% (275) DivIVA family protein
M. tuberculosis H37RvRv2145cwag311e-11078.79% (264) hypothetical protein Rv2145c
M. leprae Br4923MLBr_00922ag841e-10171.27% (268) immunogenic protein, antigen 84
M. abscessus ATCC 19977MAB_2017-1e-10572.99% (274) immunogenic protein antigen 84
M. marinum MMMAR_3185wag311e-11378.81% (269) secreted antigen Wag31
M. avium 104MAV_2345-1e-10277.34% (256) Wag31 protein
M. smegmatis MC2 155MSMEG_4217-1e-11880.51% (272) DivIVA protein
M. ulcerans Agy99MUL_3493wag311e-11478.81% (269) secreted antigen Wag31
M. vanbaalenii PYR-1Mvan_3515-1e-12282.35% (272) DivIVA family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2996|M.gilvum_PYR-GCK          MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLR
Mvan_3515|M.vanbaalenii_PYR-1       MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLR
TH_2373|M.thermoresistible__bu      MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELARLIEENTDLR
MSMEG_4217|M.smegmatis_MC2_155      MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENADLR
MMAR_3185|M.marinum_M               MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MUL_3493|M.ulcerans_Agy99           MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MAV_2345|M.avium_104                ----------MAFSKPPIGKRGYNEDEVDAFLDLVEAELTRLIEENSDLR
Mb2169c|M.bovis_AF2122/97           MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
Rv2145c|M.tuberculosis_H37Rv        MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MLBr_00922|M.leprae_Br4923          MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTQLIEENSDLR
MAB_2017|M.abscessus_ATCC_1997      MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELARLIEENSDLR
                                              :************************* **::*****:***

Mflv_2996|M.gilvum_PYR-GCK          QRISELDHELGQARAGGAAA----QPTQTIPAYEPEPEPAPE-PEPEPVY
Mvan_3515|M.vanbaalenii_PYR-1       QRVAELDQELSAARRGEGGV----QATQTLPVYEPEPEPAPA-PEP--VY
TH_2373|M.thermoresistible__bu      QRVAELDQELQAARAAAGGG----QSTQAIPLYQPEPEPEPA-PQP----
MSMEG_4217|M.smegmatis_MC2_155      QRVAELDQELAAARSGAGASS---QATSSIPLYEPEPEPAPAPPQP----
MMAR_3185|M.marinum_M               QRIAELDQELAAGAGGGAAVT--AQPTQAMPVY--EPEPEPAKPAA----
MUL_3493|M.ulcerans_Agy99           QRIAELDQELAAGAGGGAAVT--AQPTQAMPVY--EPEPEPAKPAA----
MAV_2345|M.avium_104                QRIEELDQELAAGGGAAAPAA--AAPTQAIPVA--EPEPVKAAPAA----
Mb2169c|M.bovis_AF2122/97           QRINELDQELAAGGGAGVTP----QATQAIPAY--EPE--PGKPAP----
Rv2145c|M.tuberculosis_H37Rv        QRINELDQELAAGGGAGVTP----QATQAIPAY--EPE--PGKPAP----
MLBr_00922|M.leprae_Br4923          QRIEELDHELAAGGGTGAGPVIAVQPTQALSTF--EPELVSAKQAP----
MAB_2017|M.abscessus_ATCC_1997      QRVQELDQELAEARKGGGAAPVYEAPKPEKKPEPAKPEPTPAPVVA----
                                    **: ***:**  .            ..        :**       .    

Mflv_2996|M.gilvum_PYR-GCK          EAPAPAAQQAAPATEDQHLRAAKVLSLAQDTADRLTSSAKAESEKMLADA
Mvan_3515|M.vanbaalenii_PYR-1       EA-APTPAPAAPVTEDQHLRAAKVLSLAQDTADRLTSSAKAESEKMLSDA
TH_2373|M.thermoresistible__bu      -------EQSTAVSEDQHLKAAKVLSLAQDTADRLTSTAKAESEKMLADA
MSMEG_4217|M.smegmatis_MC2_155      -VYEAPAQPAAPQSEDTAVRAARVLSLAQDTADRLTSTAKAEADKLLSDA
MMAR_3185|M.marinum_M               ------PVASAATNEEQAMKAARVLSLAQDTADRLTSTAKAESDKMLSDA
MUL_3493|M.ulcerans_Agy99           ------PVASAATNEEQAMKAARVLSLAQDTADRLTSTAKAESDKMLSDA
MAV_2345|M.avium_104                ------AVS----NEEQAIKAARVLSLAQDTADRLTSTAQAESEKMLADA
Mb2169c|M.bovis_AF2122/97           ------AAVSAGMNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADA
Rv2145c|M.tuberculosis_H37Rv        ------AAVSAGMNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADA
MLBr_00922|M.leprae_Br4923          ------VAAVAETAEELAMKATRVLSLAQDTADQLTSTAKVESDKMLADA
MAB_2017|M.abscessus_ATCC_1997      ------AAPAGASTEEHHVRAAKILGLAQDTADRLTGNAKSESEKMLADA
                                                  *:  ::*:::*.*******:**..*: *::*:*:**

Mflv_2996|M.gilvum_PYR-GCK          RAQADQLVTEARQTAETTVTEARQRADAMLADAQSRSETQLRQAQEKADA
Mvan_3515|M.vanbaalenii_PYR-1       RAQADQMVTEARQTAETTVAEARQRADAMLADAQNRSETQLRQAQEKADA
TH_2373|M.thermoresistible__bu      RAQADAMIAEARSTAETTIADARQRSEAMLNDAKTRSEAQLRQAQEKADA
MSMEG_4217|M.smegmatis_MC2_155      RAQAEAMVSDARQTAETTVSEARQRADAMLADAQTRSEAQLRQAQEKADA
MMAR_3185|M.marinum_M               RANADQILSEARHTAETTVTEARQRADGMLADAQARSESQLRQAQEKADA
MUL_3493|M.ulcerans_Agy99           RANADQILSEARHTAETTVTEARQRADGMLADAQARSESQLRQAQEKADA
MAV_2345|M.avium_104                RANADQILSEARSTAETTVAEARQRADAMLADAQARSEAQLRQAQEKADA
Mb2169c|M.bovis_AF2122/97           RANAEQILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADA
Rv2145c|M.tuberculosis_H37Rv        RANAEQILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADA
MLBr_00922|M.leprae_Br4923          RVNADQILGEARLTAEATVAEAQQRADAMLADAQTRSEVQSRQAQEKADA
MAB_2017|M.abscessus_ATCC_1997      RANADQIVSEARATAEKTVTEARTKAEALLSDAQTRSETQLRQAQEKADA
                                    *.:*: :: :** **: *:::*: :::.:* **: *** * *********

Mflv_2996|M.gilvum_PYR-GCK          LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
Mvan_3515|M.vanbaalenii_PYR-1       LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
TH_2373|M.thermoresistible__bu      LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MSMEG_4217|M.smegmatis_MC2_155      LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MMAR_3185|M.marinum_M               LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MUL_3493|M.ulcerans_Agy99           LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MAV_2345|M.avium_104                LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
Mb2169c|M.bovis_AF2122/97           LQADAERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLE
Rv2145c|M.tuberculosis_H37Rv        LQADAERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLE
MLBr_00922|M.leprae_Br4923          LQAEAERKHSEIMGAISQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MAB_2017|M.abscessus_ATCC_1997      LQSDAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
                                    **::**********:*.***:*****************************

Mflv_2996|M.gilvum_PYR-GCK          ELGTRGSAAPVDTGA----NND-GGVNQFNRGNN-
Mvan_3515|M.vanbaalenii_PYR-1       ELGQRGSAAPVDSGA----NND-GGFNQFNRGNN-
TH_2373|M.thermoresistible__bu      ELGQRGSAAPVDSTA----NSDSGAFNQFTRGSN-
MSMEG_4217|M.smegmatis_MC2_155      ELGQRGSAAPVDSSA----NSDASGFGQFNRGNN-
MMAR_3185|M.marinum_M               ELGQRGSAAPVDS------SADAGGFEQFNRGNN-
MUL_3493|M.ulcerans_Agy99           ELGQRGSAAPVDS------SADAGGFEQFNRGNN-
MAV_2345|M.avium_104                ELGQRGSAAPVDS------SADAGGFDQFNRGNN-
Mb2169c|M.bovis_AF2122/97           ELGQRGSAAPVDS------NADAGGFDQFNRGKN-
Rv2145c|M.tuberculosis_H37Rv        ELGQRGSAAPVDS------NADAGGFDQFNRGKN-
MLBr_00922|M.leprae_Br4923          ELGQRGSAAPVDS------NADAGGFDQFNRGNN-
MAB_2017|M.abscessus_ATCC_1997      ELGQRGSAAPVDAGASNENASKEAGFGQFNRGNNY
                                    *** ********:        . ... **.**.*