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MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLRQRISELDHELGQARAGGAAA QPTQTIPAYEPEPEPAPEPEPEPVYEAPAPAAQQAAPATEDQHLRAAKVLSLAQDTADRLTSSAKAESEK MLADARAQADQLVTEARQTAETTVTEARQRADAMLADAQSRSETQLRQAQEKADALQADAERKHSEIMGT INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGTRGSAAPVDTGANNDGGVNQFNRGNN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2996 | - | - | 100% (274) | DivIVA family protein |
| M. gilvum PYR-GCK | Mflv_4194 | - | 5e-12 | 36.36% (121) | hypothetical protein Mflv_4194 |
| M. gilvum PYR-GCK | Mflv_0782 | - | 5e-06 | 47.50% (40) | hypothetical protein Mflv_0782 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2169c | wag31 | 1e-111 | 77.74% (274) | hypothetical protein Mb2169c |
| M. tuberculosis H37Rv | Rv2145c | wag31 | 1e-111 | 77.74% (274) | hypothetical protein Rv2145c |
| M. leprae Br4923 | MLBr_00922 | ag84 | 1e-104 | 73.02% (278) | immunogenic protein, antigen 84 |
| M. abscessus ATCC 19977 | MAB_2017 | - | 1e-115 | 77.78% (279) | immunogenic protein antigen 84 |
| M. marinum M | MMAR_3185 | wag31 | 1e-116 | 80.14% (277) | secreted antigen Wag31 |
| M. avium 104 | MAV_2345 | - | 1e-105 | 78.03% (264) | Wag31 protein |
| M. smegmatis MC2 155 | MSMEG_4217 | - | 1e-123 | 82.25% (276) | DivIVA protein |
| M. thermoresistible (build 8) | TH_2373 | wag31 | 1e-117 | 78.18% (275) | CONSERVED HYPOTHETICAL PROTEIN WAG31 |
| M. ulcerans Agy99 | MUL_3493 | wag31 | 1e-116 | 80.14% (277) | secreted antigen Wag31 |
| M. vanbaalenii PYR-1 | Mvan_3515 | - | 1e-134 | 89.42% (274) | DivIVA family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2996|M.gilvum_PYR-GCK MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLR
Mvan_3515|M.vanbaalenii_PYR-1 MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLR
TH_2373|M.thermoresistible__bu MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELARLIEENTDLR
MSMEG_4217|M.smegmatis_MC2_155 MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENADLR
MMAR_3185|M.marinum_M MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MUL_3493|M.ulcerans_Agy99 MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MAV_2345|M.avium_104 ----------MAFSKPPIGKRGYNEDEVDAFLDLVEAELTRLIEENSDLR
Mb2169c|M.bovis_AF2122/97 MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
Rv2145c|M.tuberculosis_H37Rv MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MLBr_00922|M.leprae_Br4923 MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTQLIEENSDLR
MAB_2017|M.abscessus_ATCC_1997 MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELARLIEENSDLR
:************************* **::*****:***
Mflv_2996|M.gilvum_PYR-GCK QRISELDHELGQARAGGAAA----QPTQTIPAYEPEPEPAPE-PEPEPVY
Mvan_3515|M.vanbaalenii_PYR-1 QRVAELDQELSAARRGEGGV----QATQTLPVYEPEPEPAPA-PEP--VY
TH_2373|M.thermoresistible__bu QRVAELDQELQAARAAAGGG----QSTQAIPLYQPEPEPEPA-PQP----
MSMEG_4217|M.smegmatis_MC2_155 QRVAELDQELAAARSGAGASS---QATSSIPLYEPEPEPAPAPPQP----
MMAR_3185|M.marinum_M QRIAELDQELAAGAGGGAAVT--AQPTQAMPVY--EPEPEPAKPAA----
MUL_3493|M.ulcerans_Agy99 QRIAELDQELAAGAGGGAAVT--AQPTQAMPVY--EPEPEPAKPAA----
MAV_2345|M.avium_104 QRIEELDQELAAGGGAAAPAA--AAPTQAIPVA--EPEPVKAAPAA----
Mb2169c|M.bovis_AF2122/97 QRINELDQELAAGGGAGVTP----QATQAIPAY--EPE--PGKPAP----
Rv2145c|M.tuberculosis_H37Rv QRINELDQELAAGGGAGVTP----QATQAIPAY--EPE--PGKPAP----
MLBr_00922|M.leprae_Br4923 QRIEELDHELAAGGGTGAGPVIAVQPTQALSTF--EPELVSAKQAP----
MAB_2017|M.abscessus_ATCC_1997 QRVQELDQELAEARKGGGAAPVYEAPKPEKKPEPAKPEPTPAPVVA----
**: ***:** . .. :** .
Mflv_2996|M.gilvum_PYR-GCK EAPAPAAQQAAPATEDQHLRAAKVLSLAQDTADRLTSSAKAESEKMLADA
Mvan_3515|M.vanbaalenii_PYR-1 EA-APTPAPAAPVTEDQHLRAAKVLSLAQDTADRLTSSAKAESEKMLSDA
TH_2373|M.thermoresistible__bu -------EQSTAVSEDQHLKAAKVLSLAQDTADRLTSTAKAESEKMLADA
MSMEG_4217|M.smegmatis_MC2_155 -VYEAPAQPAAPQSEDTAVRAARVLSLAQDTADRLTSTAKAEADKLLSDA
MMAR_3185|M.marinum_M ------PVASAATNEEQAMKAARVLSLAQDTADRLTSTAKAESDKMLSDA
MUL_3493|M.ulcerans_Agy99 ------PVASAATNEEQAMKAARVLSLAQDTADRLTSTAKAESDKMLSDA
MAV_2345|M.avium_104 ------AVS----NEEQAIKAARVLSLAQDTADRLTSTAQAESEKMLADA
Mb2169c|M.bovis_AF2122/97 ------AAVSAGMNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADA
Rv2145c|M.tuberculosis_H37Rv ------AAVSAGMNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADA
MLBr_00922|M.leprae_Br4923 ------VAAVAETAEELAMKATRVLSLAQDTADQLTSTAKVESDKMLADA
MAB_2017|M.abscessus_ATCC_1997 ------AAPAGASTEEHHVRAAKILGLAQDTADRLTGNAKSESEKMLADA
*: ::*:::*.*******:**..*: *::*:*:**
Mflv_2996|M.gilvum_PYR-GCK RAQADQLVTEARQTAETTVTEARQRADAMLADAQSRSETQLRQAQEKADA
Mvan_3515|M.vanbaalenii_PYR-1 RAQADQMVTEARQTAETTVAEARQRADAMLADAQNRSETQLRQAQEKADA
TH_2373|M.thermoresistible__bu RAQADAMIAEARSTAETTIADARQRSEAMLNDAKTRSEAQLRQAQEKADA
MSMEG_4217|M.smegmatis_MC2_155 RAQAEAMVSDARQTAETTVSEARQRADAMLADAQTRSEAQLRQAQEKADA
MMAR_3185|M.marinum_M RANADQILSEARHTAETTVTEARQRADGMLADAQARSESQLRQAQEKADA
MUL_3493|M.ulcerans_Agy99 RANADQILSEARHTAETTVTEARQRADGMLADAQARSESQLRQAQEKADA
MAV_2345|M.avium_104 RANADQILSEARSTAETTVAEARQRADAMLADAQARSEAQLRQAQEKADA
Mb2169c|M.bovis_AF2122/97 RANAEQILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADA
Rv2145c|M.tuberculosis_H37Rv RANAEQILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADA
MLBr_00922|M.leprae_Br4923 RVNADQILGEARLTAEATVAEAQQRADAMLADAQTRSEVQSRQAQEKADA
MAB_2017|M.abscessus_ATCC_1997 RANADQIVSEARATAEKTVTEARTKAEALLSDAQTRSETQLRQAQEKADA
*.:*: :: :** **: *:::*: :::.:* **: *** * *********
Mflv_2996|M.gilvum_PYR-GCK LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
Mvan_3515|M.vanbaalenii_PYR-1 LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
TH_2373|M.thermoresistible__bu LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MSMEG_4217|M.smegmatis_MC2_155 LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MMAR_3185|M.marinum_M LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MUL_3493|M.ulcerans_Agy99 LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MAV_2345|M.avium_104 LQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
Mb2169c|M.bovis_AF2122/97 LQADAERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLE
Rv2145c|M.tuberculosis_H37Rv LQADAERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLE
MLBr_00922|M.leprae_Br4923 LQAEAERKHSEIMGAISQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
MAB_2017|M.abscessus_ATCC_1997 LQSDAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLE
**::**********:*.***:*****************************
Mflv_2996|M.gilvum_PYR-GCK ELGTRGSAAPVDTGA----NND-GGVNQFNRGNN-
Mvan_3515|M.vanbaalenii_PYR-1 ELGQRGSAAPVDSGA----NND-GGFNQFNRGNN-
TH_2373|M.thermoresistible__bu ELGQRGSAAPVDSTA----NSDSGAFNQFTRGSN-
MSMEG_4217|M.smegmatis_MC2_155 ELGQRGSAAPVDSSA----NSDASGFGQFNRGNN-
MMAR_3185|M.marinum_M ELGQRGSAAPVDS------SADAGGFEQFNRGNN-
MUL_3493|M.ulcerans_Agy99 ELGQRGSAAPVDS------SADAGGFEQFNRGNN-
MAV_2345|M.avium_104 ELGQRGSAAPVDS------SADAGGFDQFNRGNN-
Mb2169c|M.bovis_AF2122/97 ELGQRGSAAPVDS------NADAGGFDQFNRGKN-
Rv2145c|M.tuberculosis_H37Rv ELGQRGSAAPVDS------NADAGGFDQFNRGKN-
MLBr_00922|M.leprae_Br4923 ELGQRGSAAPVDS------NADAGGFDQFNRGNN-
MAB_2017|M.abscessus_ATCC_1997 ELGQRGSAAPVDAGASNENASKEAGFGQFNRGNNY
*** ********: . ... **.**.*