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VFGVAMCGPSHDSSSSSAPPAVTAVPPPAPSAAPPASPAPPPAGRDYVEGMVQSNSDGTIALRTRTGSAT VDYTPQTRVVQVGPAKLADVTPGSCVNVRATPQSAPPPGAITAQSVTVTPAADGKCPPPTGFFGTVASVD GNTIAVTGLRPGGPTNVTVADSTSYQKQTPSDAQAITNGKCLGANGTQDGGVLHATMISLETCPPMGHPH HHLHLPHLPLHL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3312 | - | - | 100% (222) | hypothetical protein MAV_3312 |
| M. avium 104 | MAV_3310 | - | 3e-30 | 38.05% (226) | 27 kDa lipoprotein antigen |
| M. avium 104 | MAV_1296 | - | 2e-07 | 28.57% (147) | hypothetical protein MAV_1296 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3377c | PE_PGRS50a | 2e-05 | 30.30% (132) | hypothetical protein Mb3377c |
| M. gilvum PYR-GCK | Mflv_0271 | - | 2e-05 | 26.35% (167) | hypothetical protein Mflv_0271 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2743 | - | 3e-32 | 36.89% (244) | hypothetical protein MAB_2743 |
| M. marinum M | MMAR_4294 | - | 4e-05 | 27.88% (165) | hypothetical protein MMAR_4294 |
| M. smegmatis MC2 155 | MSMEG_6099 | - | 3e-05 | 25.58% (129) | transmembrane protein rich in alanine |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1096 | mmpL3 | 3e-05 | 29.47% (190) | transmembrane transport protein MmpL3 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1096|M.ulcerans_Agy99 MFAWWGRTVYRYRFIVIGVTVALCLGGGVFGLSLGKHVTQSGFYDEGSQS
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1096|M.ulcerans_Agy99 VTASILGDEVYGRDRTGHIVAVFKAPDGKTVNDPAWSKKITDQLNQFVKD
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1096|M.ulcerans_Agy99 HPDQVLGWAGYLRAPDSTSPVIKGMATDDKKYTFVSIPLKGDDDDTILNN
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1096|M.ulcerans_Agy99 YKDIAPSLQKLDGGTVQLAGLEPVAEGLIGTIATDQRRMEVLALPLVAVV
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1096|M.ulcerans_Agy99 LFLVFGGAVAACLPVMVGGLSIAGALGILRLVAVFGPVHFFAQPVVSLIG
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
Mb3377c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0271|M.gilvum_PYR-GCK -----------------------------------------------MRS
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1096|M.ulcerans_Agy99 LGIAVDYGLFVVSRFREEIAEGYDTETAVRRTVMTAGRTVAFSAVLIMAS
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M ------------MASTWSLSKGLAAVVVTSAAAFG--------LCPGAAA
Mb3377c|M.bovis_AF2122/97 MVMSLMVAPELVAAAAADLTGIGQAISAANAAAAG--------PTTQVLA
Mflv_0271|M.gilvum_PYR-GCK CLGVSLGTANLVAVADGRATVRPAAVTVPSGLSVTGFVERVGDPVPLVLA
MSMEG_6099|M.smegmatis_MC2_155 ----MLLVLAILASSALVFTNRVELLKLAVILALWAAVVAAFVSVIYRRQ
MUL_1096|M.ulcerans_Agy99 GASLLMLPQGFVKSLTYALLAAVGLAALLSITLLPACLGVLGRHVDALGV
MAV_3312|M.avium_104 -------------------------------MFG----------------
MAB_2743|M.abscessus_ATCC_1997 ---------------------MTPTQTLAQPRFARGA-------------
MMAR_4294|M.marinum_M DPAAPQPNPNPQLPGLPALAQLSPIIQQAAGNPEQAT-------------
Mb3377c|M.bovis_AF2122/97 AAGDEVSAAIAALFGTHAQEYQALSARVATFHEQFVR-------------
Mflv_0271|M.gilvum_PYR-GCK DHSVHRPETLAAAAVEDLTRWASPQRRPDLVTVAVPA-------------
MSMEG_6099|M.smegmatis_MC2_155 SDLDQAKARDLKLVYDLQLDREISARREYELTVETQL-------------
MUL_1096|M.ulcerans_Agy99 RTAFRVPFLRNWKVSRAYLNWLADRLQKTKTREEVEAGFWGNLTNRVMRR
MAV_3312|M.avium_104 -----------------------VAMCGPSHDSSSSSAPPAVTAVPP---
MAB_2743|M.abscessus_ATCC_1997 ----------------------LLAFAGLTAFSVAACGTHGDTNAAS---
MMAR_4294|M.marinum_M ----------------------QLLMAAAQAFAHNPAAPTESRNVASSVN
Mb3377c|M.bovis_AF2122/97 ----------------------SLTAAGSAYATAEAANASPLQALEQQVL
Mflv_0271|M.gilvum_PYR-GCK ----------------------HWSGAAIGAFRSAAPHVTVVSEVSAAVT
MSMEG_6099|M.smegmatis_MC2_155 ----------------------RRELASELRAQAADEVAALRAELAALRA
MUL_1096|M.ulcerans_Agy99 PLVFAIPIVLGMILLVIPLFNLSLGGMSEKYLPPNNAVRQSQEHFDQLFP
.
MAV_3312|M.avium_104 --------------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4294|M.marinum_M QFVQEPVNPAPGSPPLGV--------------------------------
Mb3377c|M.bovis_AF2122/97 GAINAPTQLWLGRPLIGDGVHGAPGTGQPGGAGGLLWG--NGGNGGSGAA
Mflv_0271|M.gilvum_PYR-GCK ALQASPGLPTRGVIALCDLGAGGSSITLVDAGNGFAPVGDTVRLDVLSGD
MSMEG_6099|M.smegmatis_MC2_155 NLEILFDADLAHRPALETDRAAARPAGRVHASRLDVPDVETTDIRDYRSE
MUL_1096|M.ulcerans_Agy99 GYRTNPLTLVIKSTNNQPVTDQQIADIRSKAMSISGFIDQDNDADSMWQE
MAV_3312|M.avium_104 --------------PAPSAAPPASPAPPPAG--RDYVEG-MVQSNSDGTI
MAB_2743|M.abscessus_ATCC_1997 --------------TRSSAPTTSSSAPHGEHNEKGHVSG-LIVSVSGNSV
MMAR_4294|M.marinum_M ---PAPAAAPVEVAPPASAPVPHVPAPGAEPGTLAHLPAGIDPAHAAGPA
Mb3377c|M.bovis_AF2122/97 GQVGGPGGAAGLFGNGGSGGSGGAGAAGGVGGSGGWLNGNGGAGGAGGTG
Mflv_0271|M.gilvum_PYR-GCK GVDGAVLQHVLAEIETDPGGTAHVAALSGLRDRCRAAKERLSVETATGLV
MSMEG_6099|M.smegmatis_MC2_155 RTEESPIIDVPAEPHPPEDEWSFDRRPADGGFDRRPADGGFDRRPADGGF
MUL_1096|M.ulcerans_Agy99 RSYAPGGSKDPSVRVLQNGLINPGDAPTKLAELRAITPPKGLEIFVGGTP
.
MAV_3312|M.avium_104 ALRTRTGS------------------------------------------
MAB_2743|M.abscessus_ATCC_1997 EVTKQNGN------------------------------------------
MMAR_4294|M.marinum_M PVAAPAGAPPAS--------------------------------------
Mb3377c|M.bovis_AF2122/97 ANGGAGGNAWLFGAGGSGGAGTNGGVGGSGGFVYGNGGAGGIGGIGGIGG
Mflv_0271|M.gilvum_PYR-GCK WGRTTVRLTRPELEALIDDAVGGFVDAVVTTLHRYGVSPAALAAVATVGG
MSMEG_6099|M.smegmatis_MC2_155 DRRPADGGAHRFPS------------------------------------
MUL_1096|M.ulcerans_Agy99 ALEQDSIHSLFENMPAMLVILLTTTTLLMFLAFGSVVLPIKAAVMSALTL
MAV_3312|M.avium_104 --------------------------------ATVDYT------------
MAB_2743|M.abscessus_ATCC_1997 --------------------------------ATVSFG------------
MMAR_4294|M.marinum_M -----------------------APAPAAAAPASAPGT------------
Mb3377c|M.bovis_AF2122/97 NGGDAGLFGNGGAGGPGPRACRVPPASTAATAATAATA------------
Mflv_0271|M.gilvum_PYR-GCK GARIPLVTERLSEALQRPVITTPGAALAAAAGAELLAR------------
MSMEG_6099|M.smegmatis_MC2_155 ------------------QPTPQPGPQFTPQPSDEPRR------------
MUL_1096|M.ulcerans_Agy99 GSTMGILTWIFVDGHGSGVLNFTATPLTAPVIALVVAVGYGLATDYEVFL
:
MAV_3312|M.avium_104 -PQTRVV-----------QVGPAKLADVTPGSCVNVRATP----------
MAB_2743|M.abscessus_ATCC_1997 -QSTKVS-----------EIFAAQLSDVTAGSCIAAMTPP----------
MMAR_4294|M.marinum_M -APAPAA-----------APGPAPAAPAPAPAAAAPAPAP----------
Mb3377c|M.bovis_AF2122/97 -EPAATAGAAGYWLATAGPAGPAASAATVVRAALAIRVSP----------
Mflv_0271|M.gilvum_PYR-GCK -RGAEPVAQTVSVAAPMTAANATVAAPVTPLAWSAEADDPGAHAVFEDET
MSMEG_6099|M.smegmatis_MC2_155 -RRRRRLDEEQAPAPQAERQPTPPAPPQTPPPAAPPQAPP----------
MUL_1096|M.ulcerans_Agy99 ISRMVEARENGMSTQEAIRIGTATTGRLITAAALVLAVVAGSFVFSDLVM
.. . .
MAV_3312|M.avium_104 --------------------------------------QSAPPPG-----
MAB_2743|M.abscessus_ATCC_1997 --------------------------------------DSNPPTARRVMM
MMAR_4294|M.marinum_M --------------------------------------APAAPPAAPVAA
Mb3377c|M.bovis_AF2122/97 --------------------------------------STTVPAVTAVTA
Mflv_0271|M.gilvum_PYR-GCK VYATAYARPDVHFEPDEIDEADVEPLGWYRRPGVLFAAAACLAAVATTGL
MSMEG_6099|M.smegmatis_MC2_155 --------------------------------------RQAEPERAPEPQ
MUL_1096|M.ulcerans_Agy99 MKYLAFG--------------LMAALLLDATVVRMFLVPSVMKLLGDDCW
MAV_3312|M.avium_104 -----------AITAQSVTVTPAADGKCPPPTGF----------------
MAB_2743|M.abscessus_ATCC_1997 WPSADGSCVREHPKEQQSTSPAPTSGKRPEHEGI----------------
MMAR_4294|M.marinum_M PAPVPAPAPAAAPAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPS--
Mb3377c|M.bovis_AF2122/97 ATPAWAGPVGPAACWRVRTVPPAPPPPAAATAAMAASAPPPTHPYKPAGP
Mflv_0271|M.gilvum_PYR-GCK VLTAQVGPVEADASDIAAPVATAPVQAPTMPVEIAPPPPPVTETVAAAPA
MSMEG_6099|M.smegmatis_MC2_155 PAPQPAPQPAPQPAPEPVSAWAPPPPPPSMPPLQPSPTIEGGGWQPAPAE
MUL_1096|M.ulcerans_Agy99 WAPRWMRRLQTRIGLGEIQLPDERKRPANNGSARPPVKAALAAATARAPH
MAV_3312|M.avium_104 --------FGTVASVDG-NTIAVTGLRPG------------GPTNVTVAD
MAB_2743|M.abscessus_ATCC_1997 --------RGTVASVSG-NAITVTGTDPNGTA--------TGPTTVTVNN
MMAR_4294|M.marinum_M --------IGTNCLADG-SNIIATALSVAGPA--------TIPTPGPGPG
Mb3377c|M.bovis_AF2122/97 AVMAVMAGWSATAAPAA-PAVPVMRVPPALPVPPYNRRAVTAPMAAPGAT
Mflv_0271|M.gilvum_PYR-GCK PRVVQAAPQSPAPQRVV-AKQAAPQAVPRPAAPATETVAAPAPSTTPTPT
MSMEG_6099|M.smegmatis_MC2_155 GQWIPAGAPGSNWAAPV-QPQNGASTESAPETSTEYVGRRRAPEPAENPE
MUL_1096|M.ulcerans_Agy99 DPTHPSAPEAARPSRSGGPARTELGSAQSGPSSAGTKEIQTRASQPSDPP
.. .
MAV_3312|M.avium_104 STSYQKQTP-----------------------------SDAQAITNGKCL
MAB_2743|M.abscessus_ATCC_1997 DTTYAKRAP-----------------------------VDQNAIATGKCM
MMAR_4294|M.marinum_M QTAYVFTAVGTPGPAEVQRLPLNVTWVNLTTG-----KSGSVTLKPRSDI
Mb3377c|M.bovis_AF2122/97 AVMAEMAAPSTATAASAARAVPAVAAAPAETDSTPPPWVRPVPMAVWAAT
Mflv_0271|M.gilvum_PYR-GCK PTPSSTPTPTPSSTPTPTPTPSSTPTPTPTPTPTPTPTPTPTPTPTPTPT
MSMEG_6099|M.smegmatis_MC2_155 PTPPAEPAPEPVPEQSAPVPPVMAPPEPPERPERPRGRHYAAGADAESAA
MUL_1096|M.ulcerans_Agy99 TTRLTAPGAPPARGSSNPAPPAQTRPTTPAPPAPAPPPAPSAGQTRAMQI
.
MAV_3312|M.avium_104 GANGTQDG-GVLHATMISL-----ETCPPMGHPHHHLHLPHLPLHL----
MAB_2743|M.abscessus_ATCC_1997 AAHGTDDASGNLQATSITLRAARDGSCDGGGHEGHHQR------------
MMAR_4294|M.marinum_M NPEGPTTLTGIADTGSGSIMSTIFGQVTTKERQCQFMPTIGSTVVP----
Mb3377c|M.bovis_AF2122/97 AARAVTAVVAAPAAPRSPAPPARPGTAAPAVTAARPVMAEPVPPVM----
Mflv_0271|M.gilvum_PYR-GCK PTSTPAPTSTPPPVTSQPVPVETPTATQEPAPAETPVTEIPVTETPATET
MSMEG_6099|M.smegmatis_MC2_155 AEQDDTGETTPADAAAPALAAESATPPAPRRHRGADEEPRGQHANGQSAA
MUL_1096|M.ulcerans_Agy99 PTNRSSDTGGDPADPTAALPIQRPEGTDTEAATEQLNARGGQPDGGENPR
.
MAV_3312|M.avium_104 ------------------------
MAB_2743|M.abscessus_ATCC_1997 ------------------------
MMAR_4294|M.marinum_M ------------------------
Mb3377c|M.bovis_AF2122/97 ------------------------
Mflv_0271|M.gilvum_PYR-GCK PATECVPTAELAC-----------
MSMEG_6099|M.smegmatis_MC2_155 ELLARFQAAPTTGGRRRRRDE---
MUL_1096|M.ulcerans_Agy99 PRRRGAGGAGGLSAQDLLRREGRL